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1. 发明公开

EP2489331A2 Stent structures for use with valve replacement 有权转让
标题翻译： Stentstrukturen zur Verwendung mit Klappenersatz
公开(公告)号：EP2489331A2
公开(公告)日：2012-08-22
申请号：EP11275139.1
申请日：2011-11-04
申请人： Chuter, A. M. Timothy , Gopalakrishnamurthy, Sharath , Roeder, Blayne A. , Leewood, Alan R.
发明人： Chuter, A. M. Timothy , Gopalakrishnamurthy, Sharath , Roeder, Blayne A. , Leewood, Alan R.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2220/0016 , A61F2230/0019 , A61F2230/0078
摘要： A medical device for implantation in a patient comprises a stent (20) and a valve (120). The stent (20) comprises a proximal region (30) comprising a cylindrical shape having a first outer diameter when the stent is in an expanded state, and a distal region (70) comprising a cylindrical shape having a second outer diameter when the stent is in the expanded state. The second outer diameter is greater than the first outer diameter. A proximal region of the valve (130) is at least partially positioned within the proximal region of the stent, and the distal region (140) of the valve is at least partially positioned within one of tapered and distal regions of the stent. When implanted, the proximal region of the stent and the proximal region of the valve are aligned with a native valve, and the distal region of the valve is distally spaced-apart from the native valve.
摘要翻译：用于植入患者的医疗装置包括支架（20）和阀（120）。所述支架（20）包括近端区域（30），所述近端区域（30）包括当所述支架处于膨胀状态时具有第一外径的圆柱形形状，以及远端区域（70），当远端区域（70）包括具有第二外径的圆柱形状，处于扩张状态。第二外径大于第一外径。阀（130）的近侧区域至少部分地定位在支架的近侧区域内，并且阀的远侧区域（140）至少部分地定位在支架的锥形和远端区域之一内。当植入时，支架的近侧区域和瓣膜的近侧区域与天然瓣膜对准，并且瓣膜的远端区域与天然瓣膜远离间隔开。

2. 发明公开

EP2489331A3 Stent structures for use with valve replacement 有权转让
公开(公告)号：EP2489331A3
公开(公告)日：2012-11-07
申请号：EP11275139.1
申请日：2011-11-04
申请人： Chuter, A. M. Timothy , Gopalakrishnamurthy, Sharath , Roeder, Blayne A. , Leewood, Alan R.
发明人： Chuter, A. M. Timothy , Gopalakrishnamurthy, Sharath , Roeder, Blayne A. , Leewood, Alan R.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2220/0016 , A61F2230/0019 , A61F2230/0078
摘要： A medical device for implantation in a patient comprises a stent (20) and a valve (120). The stent (20) comprises a proximal region (30) comprising a cylindrical shape having a first outer diameter when the stent is in an expanded state, and a distal region (70) comprising a cylindrical shape having a second outer diameter when the stent is in the expanded state. The second outer diameter is greater than the first outer diameter. A proximal region of the valve (130) is at least partially positioned within the proximal region of the stent, and the distal region (140) of the valve is at least partially positioned within one of tapered and distal regions of the stent. When implanted, the proximal region of the stent and the proximal region of the valve are aligned with a native valve, and the distal region of the valve is distally spaced-apart from the native valve.

3. 发明公开

EP2478869A1 Aortic valve prosthesis 有权转让
标题翻译： Aortenklappenprothese
公开(公告)号：EP2478869A1
公开(公告)日：2012-07-25
申请号：EP11275138.3
申请日：2011-11-04
申请人： Chuter, A. M. Timothy , Gopalakrishnamurthy, Sharath , Roeder, Blayne A. , Leewood, Alan R.
发明人： Chuter, A. M. Timothy , Gopalakrishnamurthy, Sharath , Roeder, Blayne A. , Leewood, Alan R.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2250/0029
摘要： A valve (120) for implantation in a patient comprises a proximal region (130) comprising a cylindrical shape, and a distal region (170) having a generally rectangular shape comprising opposing flat surfaces (172, 174) that are separated by narrower flat sides (175a, 175b). A tapered region (150) is disposed between the proximal and distal regions, where the tapered region comprises two opposing flat surfaces (152, 154) that transition into the opposing flat surfaces of the distal region. The opposing flat surfaces of the tapered region are angled relative to the proximal and distal regions. The opposing flat surfaces at the distal end of the valve allow fluid flow therethrough during antegrade flow and are generally adjacent to one another to inhibit blood flow through the valve during retrograde flow. Optionally, at least one reinforcement member (185) may be coupled to the valve to prevent prolapse of the valve during retrograde flow.
摘要翻译：用于植入患者的瓣膜（120）包括包括圆柱形形状的近侧区域（130）和具有大致矩形形状的远侧区域（170），其包括相对的平坦表面（172,174），所述相对平坦表面由较窄的平坦侧面（175a，175b）。锥形区域（150）设置在近端区域和远端区域之间，其中锥形区域包括两个相对的平坦表面（152,154），其过渡到远端区域的相对的平坦表面。锥形区域的相对的平坦表面相对于近端区域和远端区域成一定角度。在阀的远端处的相对的平坦表面允许流体在顺行流动期间流过其中，并且通常彼此相邻，以在逆行流动期间抑制通过阀的血液流动。可选地，至少一个加强构件（185）可以联接到阀，以防止在逆行流动期间阀的脱垂。

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