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1. 发明授权

US06452920B1 Mobile terminating L2TP using mobile IP data 有权
标题翻译：使用移动IP数据的移动端接L2TP
公开(公告)号：US06452920B1
公开(公告)日：2002-09-17
申请号：US09223187
申请日：1998-12-30
申请人： David R. Comstock
发明人： David R. Comstock
IPC分类号： H04J324
CPC分类号： H04L12/4633 , H04L69/16 , H04L69/161 , H04L69/168 , H04L69/324 , H04W80/04 , Y10S370/901
摘要： In accordance with embodiments of the invention, Mobile IP binding information is used to deliver mobile terminating packets using layer-2 tunneling. When terminating packets destined for a mobile node are received by a home network for the mobile node, the Mobile IP binding is used to obtain the address of a foreign network to which the mobile node is attached. A Layer 2 Tunneling Protocol tunnel is created between the home network and the foreign network, and an outgoing L2TP call is made from the home network to the foreign network. A call is made from the foreign network to the mobile node, and a PPP session is established between the home network and the mobile node, via the Layer 2 Tunneling Protocol tunnel between the home network and the foreign network. After the PPP session is established the home network can optionally assign the mobile node a private IP address, and translate the home IP address labeling the terminating packets to the private IP address.
摘要翻译：根据本发明的实施例，移动IP绑定信息用于使用第2层隧道传送移动终端分组。当终止移动节点的分组由移动节点的归属网络接收时，移动IP绑定用于获得移动节点附加到的外部网络的地址。在家庭网络和外部网络之间创建二层隧道协议隧道，从家庭网络到外部网络进行外向L2TP呼叫。通过国外网络向移动节点进行呼叫，并通过家庭网络与外部网络之间的二层隧道协议隧道，在家庭网络与移动节点之间建立PPP会话。在建立PPP会话之后，家庭网络可以选择性地为移动节点分配私有IP地址，并将归属IP地址转换为将终止分组标记为私有IP地址。

2. 发明授权

US4288571A Polyester compositions 失效
标题翻译：聚酯组合物
公开(公告)号：US4288571A
公开(公告)日：1981-09-08
申请号：US336120
申请日：1973-02-26
申请人： Lowell R. Comstock , Percy L. Smith
发明人： Lowell R. Comstock , Percy L. Smith
IPC分类号： C08L67/06
CPC分类号： C08L67/06
摘要： The disclosure of this application is directed to unsaturated polyester compositions, containing as a low-profile additive a carboxyl containing thermoplastic polymer of a vinyl ester of an aliphatic, saturated monocarboxylic acid, which have particular utility in molding applications to form aesthetically attractive thermoset articles characterized by excellent physical properties, as for example, impact strength and by excellent surface properties such as excellent smoothness and gloss, excellent receptiveness to paints and excellent reproduction of the surface contours of the mold in which they are formed into shaped, thermoset articles.
摘要翻译：本申请的公开内容涉及不饱和聚酯组合物，其包含脂肪族饱和一元羧酸的乙烯基酯的含羧基的热塑性聚合物作为低轮廓添加剂，其在模塑应用中具有特殊用途以形成美观吸引的热固性物品，其特征在于通过优异的物理性能，例如冲击强度和优异的表面性能，例如优异的光滑度和光泽度，对油漆的接受性以及模具的表面轮廓的优异再现，其中它们形成成型的热固性制品。

3. 发明授权

US4284736A Unsaturated polyester compositions 失效
标题翻译：不饱和聚酯组合物
公开(公告)号：US4284736A
公开(公告)日：1981-08-18
申请号：US336121
申请日：1973-02-26
申请人： Lowell R. Comstock , Percy L. Smith
发明人： Lowell R. Comstock , Percy L. Smith
IPC分类号： C08L67/06
CPC分类号： C08L67/06
摘要： The disclosure of this application is directed to unsaturated polyester compositions, containing a thermoplastic terpolymer of a vinyl halide monomer, a vinyl ester of a saturated, monocarboxylic acid and as the third component, an unsaturated, dicarboxylic acid or anhydride thereof; or as the third component, a glycidyl ester of an unsaturated, monocarboxylic acid, which can be pigmented with organic and/or inorganic pigments and molded into shaped, thermoset articles such as housings for telephones, automobile heater ducts and the like which are characterized by excellent surface characteristics and color properties.
摘要翻译：本申请的公开内容涉及含有乙烯基卤单体的热塑性三元共聚物，饱和一元羧酸的乙烯基酯和作为第三组分的不饱和的二羧酸或其酸酐的不饱和聚酯组合物; 或者作为第三组分，可以用有机和/或无机颜料着色的不饱和单羧酸的缩水甘油酯，并且模制成成型的热固性制品，例如用于电话，汽车加热器管道等的外壳，其特征在于优异的表面特性和色泽特性。

4. 再颁专利

USRE31975E Polyester compositions 失效
标题翻译：聚酯组合物
公开(公告)号：USRE31975E
公开(公告)日：1985-08-27
申请号：US529737
申请日：1983-09-08
申请人： Lowell R. Comstock , Percy L. Smith
发明人： Lowell R. Comstock , Percy L. Smith
IPC分类号： C08L67/06
CPC分类号： C08L67/06
摘要： The disclosure of this application is directed to unsaturated polyester compositions, containing as a low-profile additive a carboxyl containing thermoplastic polymer of a vinyl ester of an aliphatic, saturated monocarboxylic acid, which have particular utility in molding applications to form aesthetically attractive thermoset articles characterized by excellent physical properties, as for example, impact strength and by excellent surface properties such as excellent smoothness and gloss, excellent receptiveness to paints and excellent reproduction of the surface contours of the mold in which they are formed into shaped, thermoset articles.

5. 发明授权

US07465544B2 Synthetic cofactor analogs of S-adenosylmethionine as ligatable probes of biological methylation and methods for their use 有权
标题翻译： S-腺苷甲硫氨酸的合成辅因子类似物作为生物甲基化的可连接探针及其使用方法
公开(公告)号：US07465544B2
公开(公告)日：2008-12-16
申请号：US11330370
申请日：2006-01-11
申请人： Scott R. Rajski , Lindsay R. Comstock , Rachel L. Weller
发明人： Scott R. Rajski , Lindsay R. Comstock , Rachel L. Weller
IPC分类号： C12Q1/68 , C07H21/00 , C07H19/16 , C07H19/20
CPC分类号： C07H19/16 , C07H19/20 , C07H21/04
摘要： The present invention discloses compounds and methods used to specifically target substrates of methylation by S-adenosyl-L-methionine (SAM)-dependent methyltransferases. The substrates can be peptides, single stranded nucleic acids or double stranded nucleic acids, including RNA, DNA and PNA or phospholipids. The compounds disclosed are SAM analogs that are ligated to a methylation site by the methyltransferase. Also disclosed, are reacting groups that are ligatable to the cofactor analogs and can also be used as detectable labels. The reacting group can be used to cleave the substrate providing a methylation footprint. The invention can be used clinically to determine methylation state of a gene or gene promoter such as those involved in imprinting and transcription. In some preferred embodiments, the invention includes a kit, which can include one or more suitable SAM analogs and may include one or more detectable labels. In other preferred embodiments, the invention includes a pharmaceutical composition.
摘要翻译：本发明公开了通过S-腺苷-L-甲硫氨酸（SAM）依赖性甲基转移酶特异性靶向甲基化底物的化合物和方法。底物可以是肽，单链核酸或双链核酸，包括RNA，DNA和PNA或磷脂。所公开的化合物是通过甲基转移酶连接到甲基化位点的SAM类似物。还公开的是可与辅因子类似物连接的反应基团，也可以用作可检测标记。反应基团可用于切割提供甲基化足迹的基材。本发明可用于临床确定基因或基因启动子的甲基化状态，例如涉及印记和转录的基因启动子。在一些优选实施方案中，本发明包括试剂盒，其可以包括一种或多种合适的SAM类似物，并且可以包括一种或多种可检测标记。在其它优选实施方案中，本发明包括药物组合物。

6. 发明申请

US20070225246A1 O-acetyl-ADP-ribose non-hydrolyzable analogs 审中-公开
标题翻译： O-乙酰基-ADP-核糖不可水解类似物
公开(公告)号：US20070225246A1
公开(公告)日：2007-09-27
申请号：US11728503
申请日：2007-03-26
申请人： John M. Denu , Lindsay R. Comstock
发明人： John M. Denu , Lindsay R. Comstock
IPC分类号： A61K31/7076 , C07H19/04
CPC分类号： C07H19/04
摘要： Compounds, compositions and methods for modulating cell death in target cells, particularly cancer cells are provided. The compounds are analogs of O-acetyl-ADP-ribose (OAADPr).
摘要翻译：提供了用于调节靶细胞特别是癌细胞中的细胞死亡的化合物，组合物和方法。这些化合物是O-乙酰基-ADP-核糖（OAADPr）的类似物。

7. 发明申请

US20070157364A1 High-friction glove/wrist guards for ice skating 审中-公开
标题翻译：高摩擦手套/护腕用于溜冰
公开(公告)号：US20070157364A1
公开(公告)日：2007-07-12
申请号：US11652874
申请日：2007-01-11
申请人： R. Comstock , Christine Collins
发明人： R. Comstock , Christine Collins
IPC分类号： A63B71/14
CPC分类号： A63B71/141
摘要： A protective glove/wrist guard device is provided that prevents hands from slipping out from under a falling ice skater when the ice skater extends his or her hands to break a fall. The protective glove/wrist guard device may include a palm surface portion having a high-friction surface portion, to provide both high-friction when contacting ice, and wrist support to help prevent wrist and hand injuries. Alternatively, the protective device may be in the form of a glove with a high friction material disposed on a palm surface portion of the glove.
摘要翻译：提供防护手套/手腕防护装置，防止手上的滑冰手伸出手来摔倒，防止手从跌倒的滑冰运动员滑落。防护手套/护腕装置可以包括具有高摩擦表面部分的手掌表面部分，以在接触冰时提供高摩擦力和手腕支撑件，以帮助防止手腕和手部受伤。或者，保护装置可以是设置在手套的手掌表面部分上的具有高摩擦材料的手套的形式。

8. 发明授权

US06959605B2 Incremental pressurization fluctuation counter and methods therefor 有权
标题翻译：增压增压波动计数器及其方法
公开(公告)号：US06959605B2
公开(公告)日：2005-11-01
申请号：US10377273
申请日：2003-02-27
申请人： Shawn R. Comstock , George R. Melvick , Alan L. Godfrey
发明人： Shawn R. Comstock , George R. Melvick , Alan L. Godfrey
IPC分类号： G01L23/00 , G01M99/00 , G01L7/00
CPC分类号： G01M99/007 , G01L23/00 , G01M5/0041 , G01M10/00
摘要： Apparatus for repeatedly indicating incremental pressure fluctuations and methods employing same are disclosed. A chamber may be sealed at an initial pressure and configured to respond to a pressure difference between the initial pressure and subsequent pressure within a container. The container may be filled via a valve mechanism exhibiting a first operational state that may allow for entry of material into the container while sealing the chamber at the initial pressure of the container as it began to be filled. A movable element communicating with the sealed chamber and the container may respond to a pressure differential therebetween, thus causing an indicator to indicate an incremental pressure fluctuation. The valve mechanism may exhibit a second operating state that may allow for the chamber and container pressures to be substantially equalized.
摘要翻译：公开了用于重复地指示增加的压力波动的装置和使用其的方法。室可以在初始压力下被密封并且被配置为响应容器内的初始压力和随后的压力之间的压力差。容器可以通过表现出第一操作状态的阀机构填充，该第一操作状态可允许在容器开始填充时在容器的初始压力下密封室，从而允许材料进入容器。与密封室和容器连通的可移动元件可以响应于它们之间的压力差，从而使指示器指示增加的压力波动。阀机构可以表现出第二操作状态，其可以允许室和容器压力基本相等。

9. 发明授权

US06766041B2 Retinal vasculature image acquisition apparatus and method 有权
标题翻译：视网膜血管图像采集装置及方法
公开(公告)号：US06766041B2
公开(公告)日：2004-07-20
申请号：US09753973
申请日：2001-01-03
申请人： Bruce L. Golden , Bernard E. Rollin , Ralph v. Switzer, Jr. , Carlton R. Comstock, Jr.
发明人： Bruce L. Golden , Bernard E. Rollin , Ralph v. Switzer, Jr. , Carlton R. Comstock, Jr.
IPC分类号： G06K922
CPC分类号： A01K11/008 , A61B3/145 , A61B5/117 , A61B5/1171 , A61B5/411 , G06K9/00597 , G06K2009/00932
摘要： The present invention creates a permanent record of an animal through a series of steps including, preliminarily acquiring an image of the retinal vasculature of the animal of interest; digitizing that image if the image is not a digital image; analyzing the image to determine if the image is satisfactory for further analysis; storing the image; and analyzing the image for unique anatomical landmarks. The image and data gathered therefrom may be stored in a database for later retrieval and comparison against other images. The data gathered from the image may be compared against other stored data in the database to determine the identity of the animal. Preferably, the system would also include a global positioning system (“GPS”) device which would simultaneously time and date stamp the acquired image as well as stamp the image with the location where the imaging took place by recording the latitude and longitude of that location.
摘要翻译：本发明通过一系列步骤创建动物的永久记录，包括：初步获取感兴趣的动物的视网膜脉管系统的图像; 如果图像不是数字图像，则对该图像进行数字化; 分析图像以确定图像是否令人满意进一步分析; 存储图像; 并分析图像的独特解剖标志。从其收集的图像和数据可以存储在数据库中，以便稍后检索和与其他图像进行比较。从图像收集的数据可以与数据库中的其他存储数据进行比较，以确定动物的身份。优选地，该系统还将包括一个全球定位系统（“GPS”）设备，其将同时对获取的图像进行时间和日期标记，并且通过记录该位置的纬度和经度将图像与成像发生的位置进行印记。

10. 发明授权

US4160304A Hold-open accessory for a door closer 失效
标题翻译：用于闭门器的保持开启附件
公开(公告)号：US4160304A
公开(公告)日：1979-07-10
申请号：US868254
申请日：1978-01-10
申请人： Gordon S. Smith , Theodore R. Comstock
发明人： Gordon S. Smith , Theodore R. Comstock
IPC分类号： E05F3/10 , E05F3/22 , E05F3/16
CPC分类号： E05F3/221 , E05Y2900/132 , Y10T16/27 , Y10T16/2804 , Y10T16/293
摘要： An accessory for use with a conventional door closer having a body for mounting on a hinged door or the door jamb and a spring biased rotatable shaft constantly urging the door toward a closed position. The accessory comprises a first member having a reaction plate fixed with respect to the door closer body, a second member, such as an externally splined ring, fixed with respect to the door closer shaft, and a member, such as a flanged collar, rotatably interconnecting the first and second members. The collar is threaded into a hole in the reaction plate, and has an internally splined hole accommodating and meshing with the splined ring. The force of frictional engagement between the flange and the reaction plate progressively increases as the door is opened, and at an adjustable predetermined open position of the door the frictional resistance between the flange and reaction plate is stronger than the closing force of the door closer, so that the door is held open.
摘要翻译：用于与常规的门关闭器一起使用的附件具有用于安装在铰链门或门边框上的主体以及不断地将门推向关闭位置的弹簧偏压旋转轴。附件包括第一构件，其具有相对于门关闭体固定的反作用板，相对于闭门轴固定的第二构件，例如外花键环，以及诸如法兰环的构件，可旋转地互连第一和第二成员。轴环拧入反应板上的一个孔中，并具有一个内花键孔，与花键环一起容纳和啮合。凸缘和反应板之间的摩擦接合力随着门的打开而逐渐增加，并且在门的可调预定打开位置，凸缘和反作用板之间的摩擦阻力比门闭合器的闭合力更强，使门被打开。

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