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    • 5. 发明申请
    • Polysaccharide capsules and methods of preparation
    • 多糖胶囊及其制备方法
    • US20050106233A1
    • 2005-05-19
    • US10509980
    • 2003-04-04
    • Peder AndersenOlav GaserodChristian Larsen
    • Peder AndersenOlav GaserodChristian Larsen
    • A61K8/11A61K8/19A61K8/30A61K8/72A61K8/73A61K9/48A61K9/66A61K47/04A61K47/14A61K47/32A61K47/34A61K47/36A61K47/38B29C39/10
    • A61K9/4883A61K9/4816
    • The present invention is directed to seamless capsules and methods for making seamless capsules having a high oil content. More specifically, the present invention is directed to seamless capsules, and methods for making seamless capsules, made from a process involving the steps of: (a) preparing an emulsion comprising oil, water, an emulsifier, and at least one of a water-soluble monovalent metal salt, polyvalent metal salt, and an acid, wherein said oil is present in an amount of at least 50% by weight of said emulsion; with the proviso that said emulsion does not contain marmelo mucilage; and (b) adding portions of said emulsion to an aqueous gelling bath comprised of at least one ionic polysaccharide, thereby encapsulating said portions of said emulsion in a polysaccharide gel membrane, and optionally (c) drying the resulting capsules by removing water. The capsule is, for example, an alignate gel. The capsules of the invention are suitable for a variety of applications, e.g. pharmaceutical, nutraceutical, veterinay, agricultural, cosmetic, or food applications.
    • 本发明涉及无缝胶囊和制备具有高油含量的无缝胶囊的方法。 更具体地说,本发明涉及无缝胶囊和制造无缝胶囊的方法,该方法包括以下步骤:(a)制备包含油,水,乳化剂和至少一种水溶性乳液的乳液, 可溶性一价金属盐,多价金属盐和酸,其中所述油以所述乳液的至少50重量%的量存在; 条件是所述乳液不含马尔默粘液; 和(b)将所述乳液的一部分加入到由至少一种离子多糖组成的水性凝胶浴中,从而将所述乳液的所述部分包封在多糖凝胶膜中,并任选地(c)通过除去水干燥所得胶囊。 胶囊是例如对齐凝胶。 本发明的胶囊适用于各种应用,例如, 制药,营养保健,兽医,农业,化妆品或食品应用。