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    • 5. 发明授权
    • Flow detection appartus and method
    • 流量检测系统和方法
    • US5736404A
    • 1998-04-07
    • US579367
    • 1995-12-27
    • Zia YassinzadehPaul J. Lingane
    • Zia YassinzadehPaul J. Lingane
    • G01N11/04G01N33/49G01N35/00G01N33/86G01N21/03
    • G01N11/04G01N33/4905G01N2035/00425Y10T436/117497Y10T436/25Y10T436/25625
    • Fluid sample tester assembly (12) comprises a cartridge (6) having a pressure chamber (22) and entrance port (20) connected by a passageway (24). An analyte reagent (36) is positioned along the fluid passageway so that when a liquid sample (28) is drawn through the entrance port into the passageway, the analyte reagent mixes with the sample. The sample is preferably drawn into the cartridge by temporarily reducing the volume of the pressure chamber, applying the sample to the entrance port and then returning the pressure chamber to its initial volume; this can also be done by heating the chamber, contacting the sample and then cooling the chamber. The end of the sample defines a boundary surface (30) along the fluid passageway. Positive and negative pressure is applied to the sample to cause the boundary surface to oscillate within the passageway. The position of the boundary surface is continuously monitored so that continuous boundary position data is obtained and is analyzed to obtain a flow-related characteristic, typically speed of coagulation, of the sample.
    • 流体样品测试器组件(12)包括具有通过通道(24)连接的压力室(22)和入口(20)的盒(6)。 分析物试剂(36)沿着流体通道定位,使得当液体样品(28)通过入口进入通道时,分析物试剂与样品混合。 样品优选通过临时减小压力室的体积,将样品施加到入口端口,然后使压力室返回到其初始体积而被吸入筒中; 这也可以通过加热室,接触样品然后冷却室完成。 样品的末端限定沿着流体通道的边界表面(30)。 对样品施加正压和负压,使得边界面在通道内振荡。 连续监测边界面的位置,以获得连续的边界位置数据并进行分析,以获得样品的流动相关特性,即凝固速度。
    • 10. 发明授权
    • Flow detection apparatus and method
    • 流量检测装置及方法
    • US6103196A
    • 2000-08-15
    • US53195
    • 1998-04-01
    • Zia YassinzadehPaul J. Lingane
    • Zia YassinzadehPaul J. Lingane
    • G01N11/04G01N33/49G01N35/00G01N33/86G01N21/03
    • G01N11/04G01N33/4905G01N2035/00425Y10T436/117497Y10T436/25Y10T436/25625
    • Fluid sample tester assembly (12) comprises a cartridge (6) having a pressure chamber (22) and entrance port (20) connected by a passageway (24). An analyte reagent (36) is positioned along the fluid passageway so that when a liquid sample (28) is drawn through the entrance port into the passageway, the analyte reagent mixes with the sample. The sample is preferably drawn into the cartridge by temporarily reducing the volume of the pressure chamber, applying the sample to the entrance port and then returning the pressure chamber to its initial volume; this can also be done by heating the chamber, contacting the sample and then cooling the chamber. The end of the sample defines a boundary surface (30) along the fluid passageway. Positive and negative pressure is applied to the sample to cause the boundary surface to oscillate within the passageway. The position of the boundary surface is continuously monitored so that continuous boundary position data is obtained and is analyzed to obtain a flow-related characteristic, typically speed of coagulation, of the sample.
    • 流体样品测试器组件(12)包括具有通过通道(24)连接的压力室(22)和入口(20)的盒(6)。 分析物试剂(36)沿着流体通道定位,使得当液体样品(28)通过入口进入通道时,分析物试剂与样品混合。 样品优选通过临时减小压力室的体积,将样品施加到入口端口,然后使压力室返回到其初始体积而被吸入筒中; 这也可以通过加热室,接触样品然后冷却室完成。 样品的末端限定沿着流体通道的边界表面(30)。 对样品施加正压和负压,使得边界面在通道内振荡。 连续监测边界面的位置,以获得连续的边界位置数据并进行分析,以获得样品的流动相关特性,即凝固速度。