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    • 6. 发明申请
    • METHODS FOR INTRACARDIAC SURGERY AND INTRACARDIAC DELIVERY OF THERAPIES AND DEVICES
    • 方法用于治疗和手术的输精管外科手术和输精管内输送
    • WO2015003183A1
    • 2015-01-08
    • PCT/US2014/045563
    • 2014-07-07
    • EMORY UNIVERSITYPUSKAS, John, D.
    • PUSKAS, John, D.
    • A61B17/00
    • A61N1/36114A61N1/36053
    • A method of performing an intracardiac procedure using controlled intermittent diastolic arrest (CIDA) to expand the chambers of the heart to a volume between about 75 to 200% of their normal end-diastolic volume. In one embodiment, CIDA is conducted so that cardiac arrest with cardiac distention is achieved in about 5 to 15 seconds and diastolic arrest is maintained for a time between about 5 and 90 seconds. Intracardiac procedures that are facilitated with CIDA include heart valve repair or replacement. The method involves the use of CIDA and wherein the procedure is performed in or on the heart with the use of a catheter or catheter-delivered device, therapy, or agent.
    • 使用受控的间歇性舒张停止(CIDA)进行心内手术以将心脏腔室扩张至其正常舒张末期容量的约75至200%之间的体积的方法。 在一个实施方案中,进行CIDA,使得心脏骤停在约5至15秒内达到心脏骤停,并且将舒张停止维持在约5至90秒之间的时间。 使用CIDA促进的心内手术包括心脏瓣膜修复或更换。 该方法涉及使用CIDA,并且其中使用导管或导管递送的装置,治疗剂或药剂在心脏中或心脏上进行该程序。