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1. 发明申请

WO2006119475A2 THREE DIMENSIONAL MAGNETIC RESONANCE MOTION ESTIMATION ON A SINGLE IMAGE PLANE 审中-公开
标题翻译：单一图像平面上的三维磁共振运动估计
公开(公告)号：WO2006119475A2
公开(公告)日：2006-11-09
申请号：PCT/US2006017304
申请日：2006-05-04
申请人： UNIV JOHNS HOPKINS , PRINCE JERRY L , STUBER MATTHIAS , OSMAN NAEL FAKHRY , ABD-ELMONIEM KHALED ZAKARYA
发明人： PRINCE JERRY L , STUBER MATTHIAS , OSMAN NAEL FAKHRY , ABD-ELMONIEM KHALED ZAKARYA
IPC分类号： A61B5/00
CPC分类号： G01R33/56333 , A61B5/055 , G01R33/56316
摘要： Three-dimensional MR motion estimation on a single image plane based on tagged MRI and HARP processing. Tagged magnetic resonance imaging technique encodes and automatically tracks displacement of spatially modulated object in three dimensions, encoding both in plane and through-plane motion in a single image plane without affecting acquisition speed. Post processing unravels encoding in order to directly track 3-D displacement of points within the image plane throughout image sequence. The invention is particularly suited to use on a heart for tracking and determining myocardial displacement. In one embodiment, an MR pulse sequence extends a slice following complementary spatial modulation of magnetization (CSPAMM) pulse sequence with two small z-encoding gradients immediately before the readouts in successive CSPAMM acquisitions, thereby adding a through-plane encoding from which through-plane motion can be computed from acquired images. HARP processing is used to determine in-plane motion, after which through-plane position can be determined using phase encodings. Use of balanced encodings and horizontal and vertical tags permits cancellation of systematic phase artifacts present in CSPAMM acquisitions.
摘要翻译：基于标记MRI和HARP处理的单个图像平面上的三维MR运动估计。标记的磁共振成像技术编码并自动跟踪三维空间调制对象的位移，在单个图像平面中对平面和平面运动进行编码，而不影响采集速度。后处理解开编码，以直接跟踪整个图像序列中图像平面内的点的三维位移。本发明特别适用于心脏跟踪和确定心肌位移。在一个实施例中，在连续的CSPAMM采集之前，MR脉冲序列在紧邻读出之前的两个小的z编码梯度的磁化（CSPAMM）脉冲序列的互补空间调制之后扩展切片，由此添加通过平面编码运动可以从获得的图像计算。 HARP处理用于确定面内运动，之后可以使用相位编码确定平面位置。使用平衡编码和水平和垂直标签可以取消CSPAMM采集中存在的系统相位伪影。

2. 发明申请

WO2006119475A3 THREE DIMENSIONAL MAGNETIC RESONANCE MOTION ESTIMATION ON A SINGLE IMAGE PLANE 审中-公开
公开(公告)号：WO2006119475A3
公开(公告)日：2006-11-09
申请号：PCT/US2006/017304
申请日：2006-05-04
申请人： JOHNS HOPKINS UNIVERSITY , PRINCE, Jerry L. , STUBER, Matthias , OSMAN, Nael Fakhry , ABD-ELMONIEM, Khaled Zakarya
发明人： PRINCE, Jerry L. , STUBER, Matthias , OSMAN, Nael Fakhry , ABD-ELMONIEM, Khaled Zakarya
IPC分类号： A61B3/16
摘要： Three-dimensional MR motion estimation on a single image plane based on tagged MRI and HARP processing. Tagged magnetic resonance imaging technique encodes and automatically tracks displacement of spatially modulated object in three dimensions, encoding both in plane and through-plane motion in a single image plane without affecting acquisition speed. Post processing unravels encoding in order to directly track 3-D displacement of points within the image plane throughout image sequence. The invention is particularly suited to use on a heart for tracking and determining myocardial displacement. In one embodiment, an MR pulse sequence extends a slice following complementary spatial modulation of magnetization (CSPAMM) pulse sequence with two small z-encoding gradients immediately before the readouts in successive CSPAMM acquisitions, thereby adding a through-plane encoding from which through-plane motion can be computed from acquired images. HARP processing is used to determine in-plane motion, after which through-plane position can be determined using phase encodings. Use of balanced encodings and horizontal and vertical tags permits cancellation of systematic phase artifacts present in CSPAMM acquisitions.

3. 发明申请

WO2005010711A2 ROBOTIC 5-DIMENSIONAL ULTRASOUND 审中-公开
标题翻译：机械五维超声波
公开(公告)号：WO2005010711A2
公开(公告)日：2005-02-03
申请号：PCT/US2004/023384
申请日：2004-07-21
申请人： JOHNS HOPKINS UNIVERSITY , BOCTOR, Emad, M. , CHOTI, Michael , FICHTINGER, Gabor , TAYLOR, Russell , PRINCE, Jerry, L.
发明人： BOCTOR, Emad, M. , CHOTI, Michael , FICHTINGER, Gabor , TAYLOR, Russell , PRINCE, Jerry, L.
IPC分类号： G06F
CPC分类号： A61B8/08 , A61B8/4209 , A61B8/4245 , A61B8/483 , A61B8/485
摘要： A robotic 5D ultrasound system and method, for use in a computer integrated surgical system, wherein 3D ultrasonic image data is integrated over time with strain (i.E., elasticity) image data. By integrating the ultrasound image data and the strain image data, the present invention is capable of accurately identifying a target tissue in surrounding tissue; segmenting, monitoring and tracking the target tissue during the surgical procedure; and facilitating proper planning and execution of the surgical procedure, even where the surgical environment is noisy and the target tissue is isoechoic.
摘要翻译：一种用于计算机集成手术系统的机器人5D超声系统和方法，其中3D超声图像数据随着时间的推移与应变（即，弹性）图像数据一体化。通过整合超声图像数据和应变图像数据，本发明能够准确地识别周围组织中的目标组织; 在外科手术过程中分割，监测和跟踪目标组织; 并且促进外科手术的适当规划和执行，即使在手术环境有噪声并且目标组织是等回声的情况下也是如此。

4. 发明申请

WO2005010711A3 ROBOTIC 5-DIMENSIONAL ULTRASOUND 审中-公开
标题翻译：机械五维超声波
公开(公告)号：WO2005010711A3
公开(公告)日：2005-03-17
申请号：PCT/US2004023384
申请日：2004-07-21
申请人： UNIV JOHNS HOPKINS , BOCTOR EMAD M , CHOTI MICHAEL , FICHTINGER GABOR , TAYLOR RUSSELL , PRINCE JERRY L
发明人： BOCTOR EMAD M , CHOTI MICHAEL , FICHTINGER GABOR , TAYLOR RUSSELL , PRINCE JERRY L
IPC分类号： A61B8/00 , A61B8/12 , A61B8/14 , G06F20060101
CPC分类号： A61B8/08 , A61B8/4209 , A61B8/4245 , A61B8/483 , A61B8/485
摘要： A robotic 5D ultrasound system and method, for use in a computer integrated surgical system (100), wherein 3D ultrasonic image data is integrated over time with strain (i.E., elasticity) image data. By integrating the ultrasound image data and the strain image data, the present invention is capable of accurately identifying a target tissue in surrounding tissue; segmenting, monitoring and tracking the target tissue during the surgical procedure; and facilitating proper planning and execution of the surgical procedure, even where the surgical environment is noisy and the target tissue is isoechoic.
摘要翻译：一种用于计算机集成手术系统（100）的机器人5D超声系统和方法，其中3D超声图像数据随着时间的推移与应变（i.E.，弹性）图像数据一体化。通过整合超声图像数据和应变图像数据，本发明能够精确地识别周围组织中的目标组织; 在外科手术过程中分割，监测和跟踪目标组织; 并且促进外科手术的适当规划和执行，即使在手术环境有噪声并且目标组织是等回声的情况下也是如此。

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