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    • 4. 发明申请
    • DEVICE AND METHOD FOR DETECTING AND/OR CHARACTERIZING FLUID-BORNE PARTICLES
    • US20190331601A1
    • 2019-10-31
    • US16310275
    • 2017-05-09
    • PLAIR SA
    • Denis KiselevSvetlana Kiseleva
    • G01N21/64G01N15/14
    • Measurement device for the detection and/or characterization of fluid-borne particles (9), the measurement device comprising means (1, 10) for producing a flow of fluid along a fluid flow path, a laser (2) positioned for emitting pulses of laser light polarized in a first direction of polarization, in a measurement volume of the fluid flow path, each pulse having a pulse duration, means (3) for directing pulses of laser light polarized in a second direction of polarization in the measurement volume, wherein the second direction of polarization is different from the first direction of polarization, a first optical spectrometer for capturing fluorescent light emitted by individual fluid-borne particles (9) in the measurement volume and measuring intensity of the captured fluorescent light at at least one determined wavelength at a sampling rate of at least three samples per pulse duration, wherein the means (3) for directing are configured such that they direct a pulse of laser light polarized in the second direction of polarization in the measurement volume each time a pulse of laser light emitted by the laser (2) and polarized in the first direction has crossed the measurement volume, the time delay between the moment of crossing the measurement volume by the pulse emitted by the laser and the moment of crossing the measurement volume by the pulse directed by the means (3) for directing is longer than the pulse duration and shorter than a travel time of the fluid in the measurement volume. Measurement method for the detection and/or characterization of fluid-borne particles (9) using the measurement device of the invention.
    • 6. 发明申请
    • METHOD AND DEVICE FOR DETECTION AND/OR MORPHOLOGIC ANALYSIS OF INDIVIDUAL FLUID-BORNE PARTICLES
    • 用于检测和/或形态学分析单个流体 - 颗粒粒子的方法和装置
    • WO2017129390A1
    • 2017-08-03
    • PCT/EP2017/050376
    • 2017-01-10
    • PLAIR SA
    • KISELEV, Denis
    • G01N15/02G01N15/14G01N15/10G01N21/47
    • G01N15/0211G01N15/1459G01N2015/1075G01N2015/1497G01N2021/4714
    • Measurement device for the detection and/or analysis of fluid-borne particles, the measurement device comprising means (1, 1') for producing a flow of fluid along a fluid flow path, a laser (2) positioned for emitting a beam (20) of laser light in a measurement volume of the fluid flow path; a lens set (3) for collecting laser light (23) scattered in the measurement volume by fluid-borne particles (9) contained in the flow of fluid, a photo-detector (4) positioned for the detection of scattered laser light (23) collected by the lens set (3), wherein the lens set (3) is configured for focusing the scattered light (23) in a line at a focal distance (f2) of the lens set (3), said line being perpendicular to a flow direction (y) of the flow of fluid in said measurement volume; and wherein the photo-detector (4) is a linear multipixel detector for capturing the laser light focused by the lens set (3), wherein said linear multipixel detector (4) is positioned at a distance from the focal distance (f2) of the lens set (3) and oriented with its longitudinal axis parallel to said line. Measurement method for the detection and/or analysis of fluid-borne particles, comprising the steps of producing a flow of fluid along a fluid flow path, said flow of fluid potentially containing fluid-borne particles (9) to be detected; emitting a beam (20) of laser light in a measurement volume of the fluid flow path; collecting laser light (23) scattered in the measurement volume by fluid-borne particles (9) contained in the flow of fluid and focusing said scattered light in a line at a focal distance (f2), said line being perpendicular to a flow direction (y) of the flow of fluid in said measurement volume; capturing the collected and focused scattered laser light (23) with a linear multipixel photo-detector (4) positioned at a distance from the focal distance (f2) and oriented with its longitudinal axis parallel to said line; repeating the steps of emitting, collecting and capturing a plurality of times during the time of crossing the measurement volume by an individual fluid-borne particle (9) of the smallest size measured by the measurement method.
    • 用于检测和/或分析流体运载颗粒的测量装置,所述测量装置包括用于沿着流体流动路径产生流体流的装置(1,1'),激光器(2) ),其定位成用于在流体流动路径的测量体积中发射激光束(20); 用于收集在流体流中包含的流体颗粒(9)在测量体积中散射的激光(23)的透镜组(3),设置用于检测散射激光(23)的光检测器(4) ),其中所述透镜组(3)被配置成用于将所述散射光(23)聚焦成所述透镜组(3)的焦距(f2)的直线,所述直线垂直于所述透镜组 所述测量体积中流体流动的流动方向(y); 并且其中所述光检测器(4)是用于捕获由所述透镜组(3)聚焦的激光的线性多像素检测器,其中所述线性多像素检测器(4)定位在与所述透镜组(3)的焦距(f2) 透镜组(3)并且其纵向轴线平行于所述线定向。 用于检测和/或分析流体携带颗粒的测量方法,包括以下步骤:沿流体流动路径产生流体流,所述流体流可能包含待检测的流体携带颗粒(9); 在流体流动路径的测量体积内发射激光束(20); 收集在流体流中包含的流体传播颗粒(9)散射在测量体积中的激光(23),并将所述散射光聚焦成焦距(f2)处的线,所述线垂直于流动方向( y)所述测量体积中的流体流量; 用线性多像素光电检测器(4)捕获收集并聚焦的散射激光(23),所述线性多像素光电检测器(4)定位在距焦距(f2)一定距离处并且其纵轴平行于所述线定向; 在通过由测量方法测量的最小尺寸的单个流体传播颗粒(9)越过测量容积的时间内重复发射,收集和捕获多次的步骤。
    • 9. 发明申请
    • METHOD AND DEVICE FOR DETECTION AND/OR MORPHOLOGIC ANALYSIS OF INDIVIDUAL FLUID-BORNE PARTICLES
    • US20190033191A1
    • 2019-01-31
    • US16072548
    • 2017-01-10
    • PLAIR SA
    • Denis Kiselev
    • G01N15/02G01N15/14
    • Measurement device for the detection and/or analysis of fluid-borne particles, the measurement device comprising means (1, 1′) for producing a flow of fluid along a fluid flow path, a laser (2) positioned for emitting a beam (20) of laser light in a measurement volume of the fluid flow path; a lens set (3) for collecting laser light (23) scattered in the measurement volume by fluid-borne particles (9) contained in the flow of fluid, a photo-detector (4) positioned for the detection of scattered laser light (23) collected by the lens set (3), wherein the lens set (3) is configured for focusing the scattered light (23) in a line at a focal distance (f2) of the lens set (3), said line being perpendicular to a flow direction (y) of the flow of fluid in said measurement volume; and wherein the photo-detector (4) is a linear multipixel detector for capturing the laser light focused by the lens set (3), wherein said linear multipixel detector (4) is positioned at a distance from the focal distance (f2) of the lens set (3) and oriented with its longitudinal axis parallel to said line. Measurement method for the detection and/or analysis of fluid-borne particles, comprising the steps of producing a flow of fluid along a fluid flow path, said flow of fluid potentially containing fluid-borne particles (9) to be detected; emitting a beam (20) of laser light in a measurement volume of the fluid flow path; collecting laser light (23) scattered in the measurement volume by fluid-borne particles (9) contained in the flow of fluid and focusing said scattered light in a line at a focal distance (f2), said line being perpendicular to a flow direction (y) of the flow of fluid in said measurement volume; capturing the collected and focused scattered laser light (23) with a linear multipixel photo-detector (4) positioned at a distance from the focal distance (f2) and oriented with its longitudinal axis parallel to said line; repeating the steps of emitting, collecting and capturing a plurality of times during the time of crossing the measurement volume by an individual fluid-borne particle (9) of the smallest size measured by the measurement method.