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1. 发明申请

US20070098806A1 Polymer-Based Antimicrobial Agents, Methods of Making Said Agents, and Products Incorporating Said Agents 失效
标题翻译：基于聚合物的抗微生物剂，制备所述试剂的方法和掺入所述试剂的产品
公开(公告)号：US20070098806A1
公开(公告)日：2007-05-03
申请号：US11558023
申请日：2006-11-09
申请人： Ashraf Ismail , Leonard Pinchuk , Orley Pinchuk , David Pinchuk
发明人： Ashraf Ismail , Leonard Pinchuk , Orley Pinchuk , David Pinchuk
IPC分类号： A61K9/14
CPC分类号： A61K9/145 , Y10S604/905
摘要： The present invention relates to antimicrobial agents, methods for the production of these agents, and the use of these agents. The antimicrobial agent of the present invention includes a water-soluble polymer and oligodynamic metal ions which interact with counter-ions of the polymer such that the metal ions are bound to corresponding counter-ions. The water-soluble polymer controls a sustained release of the metal ions. The oligodynamic metal ions preferably include small size metal particles (e.g., nano-sized silver particles) that interact to the water-soluble polymer as well as metal ions derived from one or more water-soluble oligodynamic metal compositions (e.g., metal sulfates and/or metal nitrates). The agent may also include one or more acids, including organic acids (such as sulfates, carboxylic acids, amines, hydroxyls, nitrates, and phosphates) and/or non-organic acids (such as boric acid and dioctylborate).
摘要翻译：本发明涉及抗微生物剂，这些制剂的制备方法以及这些试剂的用途。本发明的抗微生物剂包括与聚合物的抗衡离子相互作用的水溶性聚合物和低分子量金属离子，使得金属离子与相应的抗衡离子结合。水溶性聚合物控制金属离子的持续释放。低分子金属离子优选包括与水溶性聚合物相互作用的小尺寸金属颗粒（例如，纳米尺寸的银颗粒）以及衍生自一种或多种水溶性低分子量金属组合物的金属离子（例如金属硫酸盐和/ 或金属硝酸盐）。该试剂还可以包括一种或多种酸，包括有机酸（例如硫酸盐，羧酸，胺，羟基，硝酸盐和磷酸盐）和/或非有机酸（例如硼酸和二辛酯硼酸盐）。

2. 发明申请

US20070087023A1 Polymer-Based Antimicrobial Agents, Methods of Making Said Agents, and Applications Using Said Agents 审中-公开
标题翻译：基于聚合物的抗微生物剂，制备所述试剂的方法和使用所述试剂的应用
公开(公告)号：US20070087023A1
公开(公告)日：2007-04-19
申请号：US11558027
申请日：2006-11-09
申请人： Ashraf Ismail , Leonard Pinchuk , Orley Pinchuk , David Pinchuk
发明人： Ashraf Ismail , Leonard Pinchuk , Orley Pinchuk , David Pinchuk
IPC分类号： A01N59/16 , A01N25/00
CPC分类号： A01N59/16 , A01N59/20 , A01N25/10 , A01N2300/00
摘要： The present invention relates to antimicrobial agents, methods for the production of these agents, and the use of these agents. The antimicrobial agent of the present invention includes a water-soluble polymer and oligodynamic metal ions which interact with counter-ions of the polymer such that the metal ions are bound to corresponding counter-ions. The polymer controls a sustained release of the metal ions. The metal ions preferably include small size metal particles (e.g., nano-sized silver particles) that interact to the water-soluble polymer as well as metal ions derived from one or more water-soluble oligodynamic metal compositions (e.g., metal sulfates and/or metal nitrates). The agent may also include one or more acids, including organic acids and/or non-organic acids. In another aspect, antimicrobial agents that include a polymer and oligodynamic metal ions are used to treat or prevent citrus canker.
摘要翻译：本发明涉及抗微生物剂，这些制剂的制备方法以及这些试剂的用途。本发明的抗微生物剂包括与聚合物的抗衡离子相互作用的水溶性聚合物和低分子量金属离子，使得金属离子与相应的抗衡离子结合。聚合物控制金属离子的持续释放。金属离子优选包括与水溶性聚合物相互作用的小尺寸金属颗粒（例如，纳米尺寸的银颗粒）以及衍生自一种或多种水溶性低分子量金属组合物的金属离子（例如，金属硫酸盐和/或金属硝酸盐）。该试剂还可以包括一种或多种酸，包括有机酸和/或非有机酸。另一方面，包括聚合物和低分子动力学金属离子的抗微生物剂用于治疗或预防柑橘溃疡。

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