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    • 1. 发明授权
    • 2-nitromethylidene/2-cyanimino/2-nitro-imino-pyrrolidines and piperidines, intermediates, and their use as pesticides
    • 2-硝基亚甲基/ 2-氰基亚氨基/ 2-硝基 - 亚氨基 - 吡咯烷酮和哌啶,中间体及其作为农药的用途
    • US06353001B1
    • 2002-03-05
    • US09501464
    • 2000-02-09
    • Peter MaienfischJozef GondaOlivier JacobLaurenz Gsell
    • Peter MaienfischJozef GondaOlivier JacobLaurenz Gsell
    • A61K3144
    • C07D401/06A01N43/40A01N47/38A01N51/00C07D417/06
    • Compounds of formula: wherein A is an unsubstituted or substituted aromatic or non-aromatic, monocyclic or bicyclic heterocyclic radical wherein a ring nitrogen atom may have been replaced by a group R1 is hydrogen or C1-C3alkyl; R2 is hydrogen or C1-C3alkyl; R3 is hydrogen, an unsubstituted or substituted C1-C6alkyl, C3-C6cycloalkyl, C2-C6alkenyl or C2-C6alkynyl group, or C(═O)—R5, R5 is C1-C4alkyl, C1-C4alkoxy, an unsubstituted or substituted phenyl, phenoxy or benzyloxy group, or N(R6)2, each R6, independently of the other, is hydrogen, C1-C4alkyl or unsubstituted or substituted phenyl, X is CH—NO2, N—CN or N—NO2 and n is from 1 to 3, in free form or in salt form, and, where appropriate, tautomers of those compounds and the salts thereof, can be used as agrochemical active ingredients and can be prepared in a manner known per se.
    • 下式的化合物:其中A是未取代或取代的芳环或非芳族单环或双环杂环基,其中环氮原子可以被基团R 1取代为氢或C 1 -C 3烷基; R 2是氢或C 1 -C 3烷基; R 3是 氢,未取代或取代的C1-C6烷基,C3-C6环烷基,C2-C6链烯基或C2-C6炔基,或C(= O)-R5,R5是C1-C4烷基,C1-C4烷氧基,未取代或取代的苯基,苯氧基或 苄基氧基或N(R6)2,各自独立地为氢,C1-C4烷基或未取代或取代的苯基,X为CH-NO2,N-CN或N-NO2,n为1至3, 游离形式或盐形式,并且在适当时,这些化合物及其盐的互变异构体可用作农业化学活性成分,并且可以以本身已知的方式制备。
    • 4. 发明授权
    • Process for preparing spheroids of plant origin
    • 制备植物来源的球体的方法
    • US5733551A
    • 1998-03-31
    • US495964
    • 1995-06-28
    • Maurice JacobBernard BatailleOlivier JacobMichel Iderne
    • Maurice JacobBernard BatailleOlivier JacobMichel Iderne
    • A61K9/16A61K35/78
    • A61K9/1652
    • Compositions of natural, especially plant, constituents in the form of spheroids in particular of the medicinal type and formulations necessary to their preparation by a technical extrusion and spheronization system. Compositions characterized by the direct use of large quantities of solutions of natural, especially plant, origin such as liquid extracts adsorbed by natural or synthetic polymer-type substances. These various components are selected so that their combination permits the obtainment of a mass of a plasticity compatible with the technical extrusion and spheronization system. According to the process, liquid extract is prepared, this extract is incorporated in a substance of a polymeric type, the correctly moistened mass is extruded by micro-extrusion techniques and the extrudates are spheronized and then dried and calibrated.
    • 天然的,特别是植物的组成成分的球形,特别是药物类型和通过技术挤出和滚圆系统制备所需的配方。 组合物的特征在于直接使用大量天然的,特别是植物来源的溶液,例如由天然或合成聚合物型物质吸附的液体提取物。 选择这些各种组分使得它们的组合允许获得与技术挤出和滚圆系统相容的塑性质量。 根据该方法,制备液体提取物,将该提取物加入到聚合物类型中,通过微挤出技术挤出正确润湿的物质,并将挤出物滚圆,然后干燥和校准。
    • 5. 发明授权
    • 2-nitromethylidene/2-cyanimino/2-nitro-imino-pyrrolidines and piperidines, intermediates, and their use as pesticides
    • 2-硝基亚甲基/ 2-氰基亚氨基/ 2-硝基 - 亚氨基 - 吡咯烷酮和哌啶,中间体及其作为农药的用途
    • US06664248B2
    • 2003-12-16
    • US10341555
    • 2003-01-13
    • Peter MaienfischJozef GondaOlivier JacobLaurenz Gsell
    • Peter MaienfischJozef GondaOlivier JacobLaurenz Gsell
    • A61K3133
    • C07D401/06A01N43/40A01N47/38A01N51/00C07D417/06
    • Compounds of formula wherein A is an unsubstituted or substituted aromatic or non-aromatic, monocyclic or bicyclic heterocyclic radical wherein a ring nitrogen atom may have been replaced by a group R1 is hydrogen or C1-C3alkyl; R2 is hydrogen or C1-C3alkyl; R3 is hydrogen an unsubstituted or substituted C1-C6alkyl, C3-C6cycloalkyl, C2-C6alkenyl or C2-C6alkynyl group, or C(═O)—R5, R5 is C1-C4alkyl, C1-C4alkoxy, an unsubstituted or substituted phenyl, phenoxy or benzyloxy group, or N(R6)2, each R6, independently of the other, is hydrogen, C1-C4alkyl or unsubstituted or substituted phenyl, X is CH—NO2, N—CN or N—NO2 and n is from 1 to 3, in free form or in salt form, and, where appropriate, tautomers of those compounds and the salts thereof, can be used as agrochemical active ingredients and can be prepared in a manner known per se
    • 马来酰亚胺A的化合物是未取代或取代的芳族或非芳族单环或双环杂环基,其中环氮原子可以被基团R 1取代为氢或C 1 -C 3烷基; R 2是氢或C 1 -C 3烷基; R 3是氢 未取代或取代的C 1 -C 6烷基,C 3 -C 6环烷基,C 2 -C 6烯基或C 2 -C 6炔基,或C(= O)-R 5,R 5是C 1 -C 4烷基,C 1 -C 4烷氧基,未取代或取代的苯基,苯氧基或苄氧基, 或N(R 6)2,每个R 6彼此独立地为氢,C 1 -C 4烷基或未取代或取代的苯基,X为CH-NO 2,N-CN或N-NO 2,n为1至3,为游离形式 或盐形式,并且在适当的情况下,这些化合物及其盐的互变异构体可用作农业化学活性成分,并且可以以本身已知的方式制备
    • 6. 发明授权
    • 2-nitromethylidene/2-cyanimino/2-nitro-imino-pyrrolidines and piperidines, intermediates, and their use as pesticides
    • 2-硝基亚甲基/ 2-氰基亚氨基/ 2-硝基 - 亚氨基 - 吡咯烷酮和哌啶,中间体及其作为农药的用途
    • US06506743B2
    • 2003-01-14
    • US10013778
    • 2001-12-11
    • Peter MaienfischJozef GondaOlivier JacobLaurenz Gsell
    • Peter MaienfischJozef GondaOlivier JacobLaurenz Gsell
    • C07D4006
    • C07D401/06A01N43/40A01N47/38A01N51/00C07D417/06
    • Compounds of formula wherein A is an unsubstituted or substituted aromatic or non-aromatic, monocyclic or bicyclic heterocyclic radical wherein a ring nitrogen atom may have been replaced by a group R1 is hydrogen or C1-C3alkyl; R2 is hydrogen or C1-C3alkyl; R3 is hydrogen, an unsubstituted or substituted C1-C3-C6alkyl, C6cycloalkyl, C2-C6alkenyl or C2-C6alkynyl group, or C(═O)—R5, R5 is C1-C4alkyl, C1-C4alkoxy, an unsubstituted or substituted phenyl, phenoxy or benzyloxy group, or N(R6)2, each R6, independently of the other, is hydrogen, C1-C4alkyl or unsubstituted or substituted phenyl, X is CH—NO2, N—CN or N—NO2 and n is from 1 to 3, in free form or in salt form, and, where appropriate, tautomers of those compounds and the salts thereof, can be used as agrochemical active ingredients and can be prepared in a manner known per se.
    • 马来酰亚胺碱A的化合物是未取代或取代的芳族或非芳族单环或双环杂环基,其中环氮原子可以被基团R 1取代为氢或C 1 -C 3烷基; R 2是氢或C 1 -C 3烷基; R 3是氢, 未取代或取代的C1-C3-C6烷基,C6环烷基,C2-C6链烯基或C2-C6炔基,或C(= O)-R5,R5是C1-C4烷基,C1-C4烷氧基,未取代或取代的苯基,苯氧基或苄氧基 ,或N(R 6)2,每个R 6彼此独立地是氢,C 1 -C 4烷基或未取代或取代的苯基,X是CH-NO 2,N-CN或N-NO 2,并且n为1至3, 形式或盐形式,并且在适当的情况下,这些化合物及其盐的互变异构体可以用作农业化学活性成分,并且可以以本身已知的方式制备。
    • 7. 发明授权
    • 2-nitromethylidene/2-cyanimino/2-nitro-imino-pyrrolidines and
piperidines, intermediates, and their use as pesticides
    • 2-硝基亚甲基/ 2-氰基亚氨基/ 2-硝基 - 亚氨基 - 吡咯烷酮和哌啶,中间体及其作为农药的用途
    • US6048824A
    • 2000-04-11
    • US532553
    • 1995-11-22
    • Peter MaienfischJozef GondaOlivier JacobLaurenz Gsell
    • Peter MaienfischJozef GondaOlivier JacobLaurenz Gsell
    • A01N43/36A01N43/40A01N43/54A01N43/58A01N43/84A01N43/86A01N43/88A01N47/38A01N51/00C07D401/06C07D417/06
    • C07D401/06A01N43/40A01N47/38A01N51/00C07D417/06
    • Compounds of formula (I), wherein A is an unsubstituted or substituted aromatic or non-aromatic, monocyclic or bicyclic heterocyclic radical wherein a ring nitrogen atom may have been replaced by a group ##STR2## R.sub.1 is hydrogen or C.sub.1 -C.sub.3 alkyl; R.sub.2 is hydrogen or C.sub.1 -C.sub.3 alkyl; R.sub.3 is hydrogen, an unsubstituted or substituted C.sub.1 -C.sub.6 alkyl, C.sub.3 -C.sub.6 cycloalkyl C.sub.2 -C.sub.6 alkenyl or C.sub.2 -C.sub.6 alkynyl group, or C(.dbd.O)--R.sub.5, R.sub.5 is C.sub.1 -C.sub.4 alkyl C.sub.1 -C.sub.4 alkoxy, an unsubstituted or substituted phenyl, phenoxy or benzyloxy group, or N(R.sub.6).sub.2, each R.sub.6, independently of the other, is hydrogen, C.sub.1 -C.sub.4 alkyl or unsubstituted or substituted phenyl, X is CH--NO.sub.2, N--CN or N--NO.sub.2 and n is from 1 to 3, in free form or in salt form, and, where appropriate, tautomers of those compounds and the salts thereof, can be used as agrochemical active ingredients and can be prepared in a manner known per se.
    • PCT No.PCT / EP94 / 00963 Sec。 371日期:1995年11月22日 102(e)日期1995年11月22日PCT 1994年3月26日PCT公布。 出版物WO94 / 24124 日期:1994年10月27日,式(I)化合物其中A是未取代或取代的芳环或非芳香单环或双环杂环基,其中环氮原子可以被基团R 1取代为氢或C 1 -C 3烷基; R2是氢或C1-C3烷基; R3是氢,未取代或取代的C1-C6烷基,C3-C6环烷基C2-C6链烯基或C2-C6炔基,或C(= O)-R5,R5是C1-C4烷基C1-C4烷氧基,未取代或取代的苯基,苯氧基或 苄基氧基或N(R6)2,每个R6独立地为氢,C1-C4烷基或未取代或取代的苯基,X为CH-NO2,N-CN或N-NO2,n为1至3 ,以游离形式或盐形式,并且在适当时,这些化合物及其盐的互变异构体可以用作农业化学活性成分,并且可以以本身已知的方式制备。