专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08822674B2 Crystal form of 4-isopropylphenyl glucitol compound and process for production thereof 有权
标题翻译： 4-异丙基苯基硬糖醇化合物的结晶形式及其生产方法
公开(公告)号：US08822674B2
公开(公告)日：2014-09-02
申请号：US13816647
申请日：2011-08-19
申请人： Yoshihiro Kimura , Koreaki Imura , Naoto Osaki , Ayumi Matsushima
发明人： Yoshihiro Kimura , Koreaki Imura , Naoto Osaki , Ayumi Matsushima
IPC分类号： C07H7/04
CPC分类号： C07H15/203 , C07D309/10 , C07H1/00
摘要： A highly stable crystal of (1S)-1,5-anhydro-1-[5-(4-{(1E)-4-[(1-{[2-(dimethylamino)ethyl]amino}-2-methyl-1-oxopropan-2-yl)amino]-3,3-dimethyl-4-oxobut-1-en-1-yl}benzyl)-2-methoxy-4-(propan-2-yl)phenyl]-D-glucitol, and a process for producing the crystal are provided. Specifically, an ethanolate having the following physical properties, and a plurality of other crystal forms transformed from the ethanolate are provided: (a) Having peaks at 2θ=5.9 degrees, 17.1 degrees, 17.6 degrees and 21.5 degrees in X-ray powder diffraction (Cu—Kα); (b) Showing characteristic absorption bands at 3538 cm−1, 3357 cm−1, 2964 cm−1, 1673 cm−1, 1634 cm−1 and 1505 cm−1 in an infrared absorption spectrum; and (c) Having a melting point in a vicinity of 111° C.
摘要翻译：（1S）-1,5-脱水-1- [5-（4 - {（1E）-4 - [（1 - {[2-（二甲基氨基）乙基]氨基} -2-甲基 - -1-氧代丙-2-基）氨基] -3,3-二甲基-4-氧代丁-1-烯-1-基}苄基）-2-甲氧基-4-（丙-2-基）苯基] 葡萄糖醇，以及晶体的制造方法。具体地说，提供具有以下物理性质的乙醇化物和从乙醇化物转化的多种其它晶体形式：（a）在X射线粉末衍射中在2θ= 5.9度，17.1度，17.6度和21.5度处具有峰值（Cu-Kα）; （b）在红外吸收光谱中显示在3538cm-1,3337cm-1,2964cm-1,1673cm -1，1634cm -1和1505cm -1处的特征吸收带; 和（c）熔点在111℃附近

2. 发明申请

US20130144050A1 CRYSTAL FORM OF 4-ISOPROPYLPHENYL GLUCITOL COMPOUND AND PROCESS FOR PRODUCTION THEREOF 有权
标题翻译： 4-异丙基苯酚化合物的晶体形式及其生产方法
公开(公告)号：US20130144050A1
公开(公告)日：2013-06-06
申请号：US13816647
申请日：2011-08-19
申请人： Yoshihiro Kimura , Koreaki Imura , Naoto Osaki , Ayumi Matsushima
发明人： Yoshihiro Kimura , Koreaki Imura , Naoto Osaki , Ayumi Matsushima
IPC分类号： A61K31/7028 , C07H15/203 , C07H1/00
CPC分类号： C07H15/203 , C07D309/10 , C07H1/00
摘要： A highly stable crystal of (1S)-1,5-anhydro-1-[5-(4-{(1E)-4-[(1-{[2-(dimethylamino)ethyl]amino}-2-methyl-1-oxopropan-2-yl)amino]-3,3-dimethyl-4-oxobut-1-en-1-yl}benzyl)-2-methoxy-4-(propan-2-yl)phenyl]-D-glucitol, and a process for producing the crystal are provided. Specifically, an ethanolate having the following physical properties, and a plurality of other crystal forms transformed from the ethanolate are provided: (a) Having peaks at 2θ=5.9 degrees, 17.1 degrees, 17.6 degrees and 21.5 degrees in X-ray powder diffraction (Cu—Kα); (b) Showing characteristic absorption bands at 3538 cm−1, 3357 cm−1, 2964 cm−1, 1673 cm−1, 1634 cm−1 and 1505 cm−1 in an infrared absorption spectrum; and (c) Having a melting point in a vicinity of 111° C.
摘要翻译：（1S）-1,5-脱水-1- [5-（4 - {（1E）-4 - [（1 - {[2-（二甲基氨基）乙基]氨基} -2-甲基 - -1-氧代丙-2-基）氨基] -3,3-二甲基-4-氧代丁-1-烯-1-基}苄基）-2-甲氧基-4-（丙-2-基）苯基] 葡萄糖醇，以及晶体的制造方法。具体地，提供具有以下物理性质的乙醇化物和从乙醇化物转化的多种其它晶体形式：（a）在X射线粉末衍射（2θ= 5.9度，17.1度，17.6度和21.5度）处具有峰值 Cu-Kalpha）; （b）在红外吸收光谱中显示在3538cm-1,3337cm-1,2964cm-1,1673cm -1，1634cm -1和1505cm -1处的特征吸收带; 和（c）熔点在111℃附近

3. 发明授权

US4163863A Process for preparing a methylphenol 失效
公开(公告)号：US4163863A
公开(公告)日：1979-08-07
申请号：US877890
申请日：1978-02-15
申请人： Takeo Ikarashi , Mikio Goto , Kozo Sano , Naoto Osaki , Tetsuo Aoyama , Shigeru Horie
发明人： Takeo Ikarashi , Mikio Goto , Kozo Sano , Naoto Osaki , Tetsuo Aoyama , Shigeru Horie
IPC分类号： C07C37/08 , C07C39/07 , C07C39/06
CPC分类号： C07C37/08
摘要： A process for preparing a methylphenol from an alkylbenzene which process comprises oxidizing by molecular oxygen an alkylbenzene having one secondary alkyl group and 1-3 methyl groups of the general formula I ##STR1## where R is a secondary alkyl group and n is an integer of 1-3, acid-decomposing the oxidation product solution in the presence of an acid catalyst, stopping the acid-decomposition reaction before its completion, hydrogenating the acid decomposition product solution in the presence of a hydrogenation catalyst in the presence or absence of a solvent, and recovering the resulting methylphenol of the general formula II ##STR2## where n is an integer of 1-3 from the hydrogenation product solution.

4. 发明授权

US4013725A Process for preparing hydroperoxide 失效
标题翻译：制备氢过氧化物的方法
公开(公告)号：US4013725A
公开(公告)日：1977-03-22
申请号：US574898
申请日：1975-05-06
申请人： Eiichi Yonemitsu , Takeo Igarashi , Naoto Osaki , Tetsuo Aoyama , Yukiya Nakazato
发明人： Eiichi Yonemitsu , Takeo Igarashi , Naoto Osaki , Tetsuo Aoyama , Yukiya Nakazato
IPC分类号： C07C409/08 , C07C179/02 , C07C179/04
CPC分类号： C07C409/08 , C07C407/00
摘要： A process for preparing hydroperoxide by autoxidizing secondary alkyl group-substituted methylbenzenes in the presence of water comprises using as a catalyst a water-soluble chelate compound in which multidentate ligands are coordinated to at least one member selected from the class of cobalt, nickel, manganese, copper and iron.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式