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1. 发明授权

US08048912B2 Benzopyran derivatives having inhibitory activities against liver fibrosis and cirrhosis and their pharmaceutical uses 有权
标题翻译：具有对肝纤维化和肝硬化的抑制活性的苯并吡喃衍生物及其药物用途
公开(公告)号：US08048912B2
公开(公告)日：2011-11-01
申请号：US11794564
申请日：2005-06-15
申请人： Young-Dae Gong , Jin-Soo Seo , Moon-Kook Jeon , Wie-Jong Kwak , Yong-Baik Cho , Nam Kyu Lee , Eun Ju Lee , Jung Bum Lee , Jun Won Lee , Sukho Lee , Mi-Sook Dong , Jeong-Ran Kim
发明人： Young-Dae Gong , Jin-Soo Seo , Moon-Kook Jeon , Wie-Jong Kwak , Yong-Baik Cho , Nam Kyu Lee , Eun Ju Lee , Jung Bum Lee , Jun Won Lee , Sukho Lee , Mi-Sook Dong , Jeong-Ran Kim
IPC分类号： A61K31/352 , C07D311/60 , C07D311/70
CPC分类号： C07D311/70
摘要： The present invention relates to a novel benzopyran derivative having goodantagonistic activity on TGF-β receptor which can be effectively used as a prophylactic and therapeutic agent for liver disease as well as several fibroplasiadiseases such as hepatic fibrosis, liver cirrhosis, pulmonary fibrosis, dermatosclerosis, glomerular fibrosis and the like; and a pharmaceutical use thereof.
摘要翻译：本发明涉及一种对TGF-βb具有优异活性的新型苯并吡喃衍生物。受体，其可以有效地用作肝脏疾病的预防和治疗剂以及若干纤维平滑酶如肝纤维化，肝硬化，肺纤维化，皮肤硬化，肾小球纤维化等; 及其药物用途。

2. 发明申请

US20100099773A1 INCLUSION COMPLEX OF SIBUTRAMINE AND BETA-CYCLODEXTRIN 审中-公开
标题翻译：包含SIBUTRAMINE和BETA-CYCLODEXTRIN的复合物
公开(公告)号：US20100099773A1
公开(公告)日：2010-04-22
申请号：US12444080
申请日：2007-11-22
申请人： Jae-Sun Kim , Nam Ho Kim , Jin Young Lee , Nam Kyu Lee , Joon Gyo Oh , Yong Youn Hwang , Dong-Chul Shin , Yoon-Jung Lee , Key An Um , Sun Ho Kim , Jin-Heung Sung
发明人： Jae-Sun Kim , Nam Ho Kim , Jin Young Lee , Nam Kyu Lee , Joon Gyo Oh , Yong Youn Hwang , Dong-Chul Shin , Yoon-Jung Lee , Key An Um , Sun Ho Kim , Jin-Heung Sung
IPC分类号： A61K31/135 , A61P25/00
CPC分类号： A61K31/135 , A61K47/6951 , B82Y5/00 , C08B37/0015
摘要： The present invention relates to a sibutramine-containing inclusion complex having superior storage stability, and particularly to a pharmaceutically stable inclusion complex suitable for the drug formulation, which prepared by reacting a sibutramine (N,N-dimethyl-1-[1-(4-chlorophenyl)-cyclobutyl]-3-methylbutylamine) of Formula 1 and beta-cyclodextrin in a predetermined ratio, its preparation method and a pharmaceutical composition comprising the same.
摘要翻译：本发明涉及具有优异储存稳定性的西布曲明含量复合物，特别涉及适用于药物制剂的药学上稳定的包合络合物，其通过使西布曲明（N，N-二甲基-1- [1-（4 - 氯苯基） - 环丁基] -3-甲基丁胺）和β-环糊精，其制备方法和包含其的药物组合物。

3. 发明授权

US07601736B2 Pyridine derivatives, a process for their preparation and a pharmaceutical composition containing the same 有权
标题翻译：吡啶衍生物，其制备方法和含有它们的药物组合物
公开(公告)号：US07601736B2
公开(公告)日：2009-10-13
申请号：US10585029
申请日：2004-12-30
申请人： Hyung Ook Kim , Nam Kyu Lee , Joo Hyon Kim , Hae In Rhee , Yong-Baik Cho , Je Ho Ryu , Nam Ho Kim , Keun Ho Ryu , Jung Bum Yi , Jae Yoon Jung
发明人： Hyung Ook Kim , Nam Kyu Lee , Joo Hyon Kim , Hae In Rhee , Yong-Baik Cho , Je Ho Ryu , Nam Ho Kim , Keun Ho Ryu , Jung Bum Yi , Jae Yoon Jung
IPC分类号： A01N43/42 , A61K31/44 , C07D471/02 , C07D491/02 , C07D498/02
CPC分类号： C07D471/04 , C07D491/052
摘要： The invention relates to novel pyridine derivatives having an inhibitory effect on production of cytokines, which are involved in inflammatory responses, thus suggesting its usefulness as therapeutic agents for treating diseases related to inflammation, immune, chronic inflammation as well as an agent having an anti-inflammatory and analgesic effect. Further, this invention relates to a method of manufacturing the same and a pharmaceutical composition containing the same.
摘要翻译：本发明涉及具有抑制细胞因子产生抑制作用的新型吡啶衍生物，其涉及炎性反应，因此表明其用作治疗与炎症，免疫，慢性炎症有关的疾病的治疗剂以及具有抗炎作用的药物，炎症和镇痛作用。此外，本发明涉及其制造方法和含有该组合物的药物组合物。

4. 发明申请

US20090163574A1 Stable Pharmaceutical Composition Containing Docetaxel and a Method of Manufacturing the Same 失效
标题翻译：含有多西紫杉醇的稳定药物组合物及其制造方法
公开(公告)号：US20090163574A1
公开(公告)日：2009-06-25
申请号：US12301700
申请日：2007-05-22
申请人： Nam Ho Kim , Jin Young Lee , Jae-Sun Kim , Nam Kyu Lee , Woo Jae Jang , Joon Gyo Oh , Yoon-Jung Lee , Woong Sik Kim , Jin-Heung Sung , Key An Um
发明人： Nam Ho Kim , Jin Young Lee , Jae-Sun Kim , Nam Kyu Lee , Woo Jae Jang , Joon Gyo Oh , Yoon-Jung Lee , Woong Sik Kim , Jin-Heung Sung , Key An Um
IPC分类号： A61K31/337
CPC分类号： A61K9/0019 , A61K9/19 , A61K31/337 , A61K31/724 , A61K47/10 , A61K47/32 , A61K47/38 , A61K47/40 , A61K2300/00
摘要： The present invention relates to a stable pharmaceutical composition for injection containing docetaxel and a method of preparing the same. More particularly, the present invention relates to a pharmaceutical composition for injection containing docetaxel having better storage stability than conventional medications, which is prepared by dissolving docetaxel, a water-insoluble compound, in distilled water after mixing it with cyclodextrin (CD) and a water-soluble polymer such as hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) and lyophilizing the mixture, and a method of preparing the same.
摘要翻译：本发明涉及含有多西紫杉醇的稳定的注射用药物组合物及其制备方法。更具体地说，本发明涉及含有多西紫杉醇的药物组合物，其具有比常规药物更好的储存稳定性，其通过将多巴紫杉醇，水不溶性化合物与环糊精（CD）和水混合后在蒸馏水中溶解而制备可溶性聚合物如羟丙基甲基纤维素（HPMC），聚乙二醇（PEG）或聚乙烯吡咯烷酮（PVP），并将混合物冷冻干燥及其制备方法。

5. 发明申请

US20080249314A1 Optical Resolution Method of Amlodipine 失效
标题翻译：氨氯地平的光学分辨方法
公开(公告)号：US20080249314A1
公开(公告)日：2008-10-09
申请号：US11792281
申请日：2005-12-02
申请人： Jae-Sun Kim , Jin Young Choi , Nam Ho Kim , Nam Kyu Lee
发明人： Jae-Sun Kim , Jin Young Choi , Nam Ho Kim , Nam Kyu Lee
IPC分类号： C07D213/803
CPC分类号： C07D211/90
摘要： The present invention relates to a method for optical resolution of amlodipines by using isopropanol solvent and optically active O,O′-dibenzoyl tartaric acid as chiral reagent. More particularly, the present invention relates to a method comprising (a) obtaining (R)— or (S)-amlodipine dibenzoyl tartrate salt or solvate thereof by reacting (R,S)-amlodipines with optically active O,O′-dibenzoyl tartaric acid in isopropanol solvent, and (b) treating the (R)— or (S)-amlodipine salt with a base, thus obtaining optically active amlodipine.
摘要翻译：本发明涉及通过使用异丙醇溶剂和光学活性的O，O-二苯甲酰基酒石酸作为手性试剂来旋光拆分氨氯地平的方法。更具体地说，本发明涉及一种方法，其包括（a）通过使（R，S） - 氨氯地平与光学活性的O，O-二苯甲酰基酒石酸盐反应获得（R） - 或（S） - 氨氯地平二苯甲酰酒石酸盐或其溶剂合物异丙醇溶剂中的酸，和（b）用碱处理（R） - 或（S） - 氨氯地平盐，从而得到光学活性的氨氯地平。

6. 发明授权

US07138994B2 Energy recovering circuit with boosting voltage-up and energy efficient method using the same 有权
标题翻译：能量回收电路采用升压升压和节能方法
公开(公告)号：US07138994B2
公开(公告)日：2006-11-21
申请号：US10416286
申请日：2001-11-09
申请人： Jang-Hwan Cho , Nam-Kyu Lee , Cheul-U Kim , Feel-Soon Kang , Eung-Kwan Lee , Jae-Hwa Ryu , Sung-Ho Kang
发明人： Jang-Hwan Cho , Nam-Kyu Lee , Cheul-U Kim , Feel-Soon Kang , Eung-Kwan Lee , Jae-Hwa Ryu , Sung-Ho Kang
IPC分类号： G09G3/28 , G09G5/00
CPC分类号： G09G3/2965 , G09G2310/06
摘要： There is disclosed an energy recovering circuit with boosting voltage-up and an energy efficient method using the same that are capable of boosting the voltage factor of an energy recovered from the panel to rapidly re-appl it to the panel, to thereby reduce the charging time of a panel capacitor and improve its energy recovery efficiency. An energy recovering circuit according to the present invention includes a voltage boosting circuit for boosting a voltage factor of an energy recovered from a panel and supplying the boosted energy to the panel. An energy efficient method according to the present invention includes steps of recovering an energy from a panel to a closed loop; and a controlling the closed loop in order to supplying the energy with its voltage factor boosted to the panel.
摘要翻译：公开了一种具有升压升压的能量回收电路和使用该能量回收电路的能量回收电路，其能够提高从面板回收的能量的电压因子，以快速地将其重新应用于面板，从而减少充电面板电容器的时间并提高其能量回收效率。根据本发明的能量恢复电路包括升压电路，用于升高从面板回收的能量的电压因数并将升压的能量提供给面板。根据本发明的能量效率方法包括将能量从面板回收到闭环的步骤; 并且控制闭环以便向能量提供其升压到面板的电压因数。

7. 发明申请

US20060142050A1 Method and device for telephone number search in a mobile terminal 失效
公开(公告)号：US20060142050A1
公开(公告)日：2006-06-29
申请号：US11312135
申请日：2005-12-20
申请人： Nam-Kyu Lee
发明人： Nam-Kyu Lee
IPC分类号： H04M1/00
CPC分类号： H04M1/274558
摘要： Disclosed is a method and device for searching for a telephone number in a mobile terminal having a direction key that consists of a left arrow, a right arrow, an up arrow and a down arrow. The method includes displaying one or more consecutive digits input by a user in a standby mode of the mobile terminal; and when a quick search key and any arrow of the direction key are pressed simultaneously, searching for a telephone number including the displayed digits in a position corresponding to the pressed arrow.

8. 发明授权

US08355697B2 Apparatus and method for providing broadcast service in mobile communication system 有权
标题翻译：在移动通信系统中提供广播服务的装置和方法
公开(公告)号：US08355697B2
公开(公告)日：2013-01-15
申请号：US12018633
申请日：2008-01-23
申请人： Yong-Seock Choi , Nam-Kyu Lee
发明人： Yong-Seock Choi , Nam-Kyu Lee
IPC分类号： H04M1/66
CPC分类号： H04L63/08 , H04H20/57 , H04H60/15 , H04N7/17318 , H04N21/25875 , H04N21/41407 , H04N21/6334 , H04W4/06 , H04W12/06
摘要： A user authentication process when a portable terminal receives multimedia broadcasting requiring authentication is provided. The broadcasting is provided by a mobile communication system including a portable terminal capable of a user authentication process if a message indicating that broadcasting requires the authentication process is received while using the broadcast service, the portable terminal provides the broadcast service if the authentication process is successful, and stops the broadcast service if the authentication process fails; and a multimedia broadcast server for transmitting to the portable terminal the message, which indicates that the broadcasting requires the authentication process, when the broadcasting requires the authentication process while the broadcast service is being provided to the portable terminal.
摘要翻译：提供便携式终端接收需要认证的多媒体广播时的用户认证处理。如果在使用广播服务的情况下接收到指示广播需要认证处理的消息，那么广播由包括能够进行用户认证处理的便携式终端的移动通信系统提供，便携式终端如果认证过程成功则提供广播服务如果认证过程失败，则停止广播业务; 以及多媒体广播服务器，用于当广播服务被提供给便携式终端时，当广播需要认证过程时，向便携式终端发送指示广播需要认证过程的消息。

9. 发明申请

US20100069632A1 SALTS OF PYRROLOPYRIMIDINONE DERIVATIVES AND PROCESS FOR PREPARING THE SAME 审中-公开
标题翻译：吡咯烷酮衍生物的制备方法及其制备方法
公开(公告)号：US20100069632A1
公开(公告)日：2010-03-18
申请号：US12307144
申请日：2007-07-03
申请人： Nam Ho Kim , Jin-Young Lee , Jae-Sun Kim , Nam Kyu Lee , Woo Jae Jang , Joo Gyo Oh , Yoon-Jung Lee , Won-No Youn , Jin-Heung Sung , Key An Um
发明人： Nam Ho Kim , Jin-Young Lee , Jae-Sun Kim , Nam Kyu Lee , Woo Jae Jang , Joo Gyo Oh , Yoon-Jung Lee , Won-No Youn , Jin-Heung Sung , Key An Um
IPC分类号： C07D487/04
CPC分类号： C07D487/04
摘要： The present invention relates to salts of a pyrrolopyrimidinone derivative having superior PDE-5 inhibition activity and a process for preparing the same. More particularly, the present invention relates to a crystalline acid addition salt prepared by reacting a pyrrolopyrimidinone derivative with an acid selected from gentisic acid, maleic acid, citric acid, fumaric acid and tartaric acid. With no hygroscopic property and superior long-term storage stability, photostability and thermal stability, the salts of the pyrrolopyrimidinone derivative are appropriate to be prepared into medications and, with superior PDE-5 inhibition activity, are useful for the treatment and prevention of erectile dysfunction, pulmonary arterial hypertension, chronic obstructive pulmonary disease, benign prostatic hypertrophy and lower urinary tract diseases.
摘要翻译：本发明涉及具有优异的PDE-5抑制活性的吡咯并嘧啶酮衍生物的盐及其制备方法。更具体地，本发明涉及通过使吡咯并嘧啶酮衍生物与选自龙胆酸，马来酸，柠檬酸，富马酸和酒石酸的酸反应制备的结晶酸加成盐。无吸湿性和优异的长期储存稳定性，光稳定性和热稳定性，吡咯并嘧啶酮衍生物的盐适于制备成药物，并且具有优异的PDE-5抑制活性，可用于治疗和预防勃起功能障碍肺动脉高压，慢性阻塞性肺疾病，良性前列腺肥大和下尿路疾病。

10. 发明授权

US07605808B2 Energy recovery apparatus and method for plasma display panel 失效
标题翻译：等离子显示面板的能量回收装置及方法
公开(公告)号：US07605808B2
公开(公告)日：2009-10-20
申请号：US10942052
申请日：2004-09-16
申请人： Nam Kyu Lee , Bong Gyun Kim , Bong Hwan Kwon , Jang Hwan Cho
发明人： Nam Kyu Lee , Bong Gyun Kim , Bong Hwan Kwon , Jang Hwan Cho
IPC分类号： G09G5/00
CPC分类号： G09G3/2965
摘要： Disclosed are an energy recovery apparatus and method for a plasma display panel. The energy recovery apparatus includes a sustain voltage source for supplying a sustain voltage, a panel capacitor formed equivalently at a discharge cell, a first charging circuit for forming a first charging path when one side of the panel capacitor is charged, a second charging circuit for forming a second charging path when the other side of the panel capacitor is charged, a first power circuit for supplying the sustain voltage to the panel capacitor and forming the first charging path, and a second power circuit for supplying a ground voltage generated from a ground voltage source to the panel capacitor and forming the second charging path. The energy recovery apparatus and method according to the present invention can decrease components in number and reduce power consumption and manufacturing cost by charging the other side of the panel capacitor using a charging voltage of one side of the panel capacitor.
摘要翻译：公开了一种用于等离子体显示面板的能量回收装置和方法。能量回收装置包括用于提供维持电压的维持电压源，在放电单元等效地形成的面板电容器，用于在面板电容器的一侧被充电时形成第一充电路径的第一充电电路;第二充电电路，当面板电容器的另一侧被充电时，形成第二充电路径，用于向面板电容器提供维持电压并形成第一充电路径的第一电源电路和用于提供从地面产生的接地电压的第二电源电路电压源到面板电容器并形成第二充电路径。根据本发明的能量回收装置和方法可以通过面板电容器的一侧的充电电压对面板电容器的另一侧进行充电来减少数量的部件并降低功耗和制造成本。

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