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1. 发明申请

US20150191409A1 Process 审中-公开
标题翻译：处理
公开(公告)号：US20150191409A1
公开(公告)日：2015-07-09
申请号：US14148974
申请日：2014-01-07
申请人： NATURALLY SCIENTIFIC TECHNOLOGIES LIMITED
发明人： Glenn RICHARDS
IPC分类号： C07C51/00 , C07C67/03 , B01F5/00 , C07C29/09
CPC分类号： C07C67/03 , C07C29/00 , C07C29/1285 , C07C51/295 , Y02E50/13 , C07C31/125 , C07C31/225 , C07C69/52 , C07C55/20
摘要： The present invention relates to a process, which is particularly suitable for the production of sebacic acid and/or 2-octanol, and also for the production of biodiesel, wherein the process is a process for the reaction of a fatty acid ester (such as castor oil, or canola or rapeseed oil) and/or a fatty acid (such as riconleic acid) with an inorganic base (such as sodium hydroxide), the process comprising the following steps: (i) providing a pressurised and heated stream of fatty acid ester and/or fatty acid; (ii) providing an inorganic base; (iii) combining the stream obtained from step (i) with the inorganic base obtained in step (ii), in the presence of water, in a reaction vessel, by injection, thereby to produce reaction mixture in the form of a pressurised and heated stream; (iv) optionally maintaining the stream obtained in step (iii) at a selected temperature and pressure; and (v) thereby obtaining a reaction product.
摘要翻译：本发明涉及一种特别适用于生产癸二酸和/或2-辛醇以及生产生物柴油的方法，其中该方法是一种脂肪酸酯（如蓖麻油或油菜籽油或菜籽油）和/或与无机碱（如氢氧化钠）的脂肪酸（如微康酸），该方法包括以下步骤：（i）提供加压和加热的脂肪酸酯和/或脂肪酸; （ii）提供无机碱; （iii）将由步骤（ⅰ）获得的物流与步骤（ⅱ）中获得的无机碱在水存在下，在反应容器中通过注射混合，由此产生加压和加热的形式的反应混合物流; （iv）任选地将步骤（iii）中获得的物流保持在选定的温度和压力下; 和（v），从而得到反应产物。

2. 发明申请

US20170067083A1 PRODUCTION OF BIOFUEL FROM TISSUE CULTURE SOURCES 审中-公开
标题翻译：从组织文化来源生产生物燃料
公开(公告)号：US20170067083A1
公开(公告)日：2017-03-09
申请号：US15231681
申请日：2016-08-08
申请人： NATURALLY SCIENTIFIC TECHNOLOGIES LIMITED
发明人： Peter Andrew WHITTON , Geoffrey Robert DIXON , William Timothy MERRELL
IPC分类号： C12P7/64
CPC分类号： C12P7/649 , C12N9/18 , C12N9/20 , C12P7/6409 , C12P7/6463 , Y02E50/13 , Y02P20/52
摘要： The present invention provides a method for the production of at least one fatty acid and/or oil from a plant cell suspension culture, the method comprising (i) maintaining a cell suspension culture of oil-producing plant cells under conditions such that the cultured cells synthesise and secrete at least one fatty acid and/or oil into the cell suspension culture medium; and (ii) extracting the thus secreted at least one fatty acid and/or oil from the cell suspension culture medium.
摘要翻译：本发明提供从植物细胞悬浮培养物生产至少一种脂肪酸和/或油的方法，所述方法包括（i）在产生培养细胞的条件下维持产油植物细胞的细胞悬浮培养合成并将至少一种脂肪酸和/或油分泌到细胞悬浮培养基中; 和（ii）从细胞悬浮培养基中提取由此分泌的至少一种脂肪酸和/或油。

3. 发明申请

US20140199726A1 PRODUCTION OF BIOFUEL FROM TISSUE CULTURE SOURCES 审中-公开
标题翻译：从组织文化来源生产生物燃料
公开(公告)号：US20140199726A1
公开(公告)日：2014-07-17
申请号：US14100197
申请日：2013-12-09
申请人： Naturally Scientific Technologies Limited
发明人： Peter Andrew WHITTON , Geoffrey Robert DIXON , William Timothy MERRELL
IPC分类号： C12P7/64
CPC分类号： C12P7/649 , C12N9/18 , C12N9/20 , C12P7/6409 , C12P7/6463 , Y02E50/13 , Y02P20/52
摘要： The present invention provides a method for the production of at least one fatty acid and/or oil from a plant cell suspension culture, the method comprising (i) maintaining a cell suspension culture of oil-producing plant cells under conditions such that the cultured cells synthesise and secrete at least one fatty acid and/or oil into the cell suspension culture medium; and (ii) extracting the thus secreted at least one fatty acid and/or oil from the cell suspension culture medium.
摘要翻译：本发明提供从植物细胞悬浮培养物生产至少一种脂肪酸和/或油的方法，所述方法包括（i）在产生培养细胞的条件下维持产油植物细胞的细胞悬浮培养合成并将至少一种脂肪酸和/或油分泌到细胞悬浮培养基中; 和（ii）从细胞悬浮培养基中提取由此分泌的至少一种脂肪酸和/或油。

4. 发明申请

WO2012160360A2 PHOTOSYNTHETIC PROCESS 审中-公开
标题翻译：光合作用
公开(公告)号：WO2012160360A2
公开(公告)日：2012-11-29
申请号：PCT/GB2012/051135
申请日：2012-05-18
申请人： NATURALLY SCIENTIFIC TECHNOLOGIES LIMITED , WHITTON, Peter Andrew
发明人： WHITTON, Peter Andrew
IPC分类号： C12P19/02 , C12P19/12 , C12P7/06 , C12P7/64 , C12R1/89 , C12R1/91
CPC分类号： C12P7/6409 , A01C3/023 , A01H4/001 , C12M1/002 , C12M3/02 , C12M21/02 , C12M23/58 , C12N1/12 , C12N5/04 , C12P7/06 , C12P7/64 , C12P19/02 , C12P19/12 , C12R1/89 , C12R1/91 , Y02E50/17
摘要： The present invention provides a method of producing a photosynthetic product, the method comprising maintaining a photosynthetic plant or algal cell suspension culture, in the presence of water, light and a carbonic acid-enriched growth medium. The carbonic acid may, for example be provided by feeding the photosynthetic plant cell suspension culture with a carbonic acid solution, a solid or liquid precursor thereof, or a gaseous mixture of carbon dioxide and one or more other gases. The invention also provides a method for producing a photosynthetic product, the method comprising maintaining a photosynthetic plant or algal cell suspension culture, in the presence of water, light and a carbon source selected from carbon dioxide and carbonic acid, wherein the culture is maintained at a pH of less than 7.0, preferably 4.5 to 5.5.
摘要翻译：本发明提供了一种生产光合产物的方法，该方法包括在水，光和富含碳酸的生长培养基的存在下保持光合植物或藻细胞悬浮培养物。碳酸可以例如通过用碳酸溶液，其固体或液体前体或二氧化碳和一种或多种其它气体的气体混合物进料光合植物细胞悬浮培养来提供。本发明还提供了一种生产光合产物的方法，该方法包括在水，光和选自二氧化碳和碳酸的碳源的存在下保持光合植物或藻细胞悬浮培养物，其中培养物保持在 pH小于7.0，优选4.5至5.5。

5. 发明授权

US10465215B2 Production of biofuel from tissue culture sources 有权
公开(公告)号：US10465215B2
公开(公告)日：2019-11-05
申请号：US15231681
申请日：2016-08-08
申请人： NATURALLY SCIENTIFIC TECHNOLOGIES LIMITED
发明人： Peter Andrew Whitton , Geoffrey Robert Dixon , William Timothy Merrell
IPC分类号： C12P7/64 , C12N9/18 , C12N9/20
摘要： The present invention provides a method for the production of at least one fatty acid and/or oil from a plant cell suspension culture, the method comprising (i) maintaining a cell suspension culture of oil-producing plant cells under conditions such that the cultured cells synthesize and secrete at least one fatty acid and/or oil into the cell suspension culture medium; and (ii) extracting the thus secreted at least one fatty acid and/or oil from the cell suspension culture medium.

6. 发明授权

US09447442B2 Production of biofuel from tissue culture sources 有权
标题翻译：从组织培养来源生产生物燃料
公开(公告)号：US09447442B2
公开(公告)日：2016-09-20
申请号：US14100197
申请日：2013-12-09
申请人： Naturally Scientific Technologies Limited
发明人： Peter Andrew Whitton , Geoffrey Robert Dixon , William Timothy Merrell
IPC分类号： C12P7/64 , C12N9/18 , C12N9/20
CPC分类号： C12P7/649 , C12N9/18 , C12N9/20 , C12P7/6409 , C12P7/6463 , Y02E50/13 , Y02P20/52
摘要： A method for the production of at least one fatty acid and/or oil from a plant cell suspension culture includes (i) maintaining a cell suspension culture of oil-producing plant cells under conditions such that the cultured cells synthesize and secrete at least one fatty acid and/or oil into the cell suspension culture medium; and (ii) extracting the thus secreted at least one fatty acid and/or oil from the cell suspension culture medium.
摘要翻译：用于从植物细胞悬浮培养物生产至少一种脂肪酸和/或油的方法包括（i）在培养的细胞合成和分泌至少一种脂肪的条件下维持产油植物细胞的细胞悬浮培养物酸和/或油进入细胞悬浮培养基; 和（ii）从细胞悬浮培养基中提取由此分泌的至少一种脂肪酸和/或油。

7. 发明授权

EP2311970B1 Method for the production of bioproducts 有权
标题翻译：一种用于生产有机产品过程
公开(公告)号：EP2311970B1
公开(公告)日：2013-04-10
申请号：EP10075755.8
申请日：2009-04-28
申请人： Naturally Scientific Technologies Limited
发明人： Whitton, Peter Andrew , Dixon, Geoffrey Robert , Merrell, William Timothy
IPC分类号： C12P7/64
CPC分类号： C12P7/649 , C12N9/18 , C12N9/20 , C12P7/6409 , C12P7/6463 , Y02E50/13 , Y02P20/52

8. 发明公开

EP2311970A1 Method for the production of bioproducts 有权
标题翻译： Verfahren zur Herstellung von Bioprodukten
公开(公告)号：EP2311970A1
公开(公告)日：2011-04-20
申请号：EP10075755.8
申请日：2009-04-28
申请人： Naturally Scientific Technologies Limited
发明人： Whitton, Peter Andrew , Dixon, Geoffrey Robert , Merrell, William Timothy
IPC分类号： C12P7/64
CPC分类号： C12P7/649 , C12N9/18 , C12N9/20 , C12P7/6409 , C12P7/6463 , Y02E50/13 , Y02P20/52
摘要： The present invention relates to a method for the production of a biological product, the method comprising (i) maintaining a first cell suspension culture of photosynthetic non-algal plant cells under conditions that include the provision of light and carbon dioxide that allow the cultured cells to photosynthesise and thereby generate and release sugars, typically mono- and/or di-saccharides (for example glucose, sucrose, and/or fructose), into the surrounding culture medium; and (ii) maintaining a second cell culture in the presence of the sugar generated by the first cell suspension culture to allow growth of the second culture and the production of a biological product.
摘要翻译：本发明涉及一种用于生产生物制品的方法，所述方法包括（i）在包括提供光和二氧化碳的条件下保持光合非藻类植物细胞的第一细胞悬浮培养物，所述条件允许培养细胞进行光合作用，由此产生和释放糖，通常是单糖和/或二糖（例如葡萄糖，蔗糖和/或果糖）到周围的培养基中; 和（ii）在由第一细胞悬浮培养产生的糖的存在下保持第二细胞培养物，以允许第二培养物的生长和生物制品的生产。

9. 发明授权

EP2664674B1 Method for the production of bioproducts 有权
标题翻译：生物制品的生产方法
公开(公告)号：EP2664674B1
公开(公告)日：2018-03-21
申请号：EP13160779.8
申请日：2009-04-28
申请人： Naturally Scientific Technologies Limited
发明人： Whitton, Peter Andrew , Dixon, Geoffrey Robert , Merrell, William Timothy
IPC分类号： C12P7/64 , C12N5/00 , C12N9/20 , C12N9/18
CPC分类号： C12P7/649 , C12N9/18 , C12N9/20 , C12P7/6409 , C12P7/6463 , Y02E50/13 , Y02P20/52
摘要： The present invention relates to a method for the production of a biological product, the method comprising (i) maintaining a first cell suspension culture of photosynthetic non-algal plant cells under conditions that include the provision of light and carbon dioxide that allow the cultured cells to photosynthesise and thereby generate and release sugars, typically mono- and/or di-saccharides (for example glucose, sucrose, and/or fructose), into the surrounding culture medium; and (ii) maintaining a second cell culture in the presence of the sugar generated by the first cell suspension culture to allow growth of the second culture and the production of a biological product.

10. 发明公开

EP2664674A2 Method for the production of bioproducts 有权
标题翻译：生物制品的生产方法
公开(公告)号：EP2664674A2
公开(公告)日：2013-11-20
申请号：EP13160779.8
申请日：2009-04-28
申请人： Naturally Scientific Technologies Limited
发明人： Whitton,, Peter Andrew , Dixon,, Geoffrey Robert , Merrell,, William Timothy
IPC分类号： C12P7/64 , C12N5/00 , C12N9/20 , C12N9/18
CPC分类号： C12P7/649 , C12N9/18 , C12N9/20 , C12P7/6409 , C12P7/6463 , Y02E50/13 , Y02P20/52
摘要： The present invention relates to an extract of at least one fatty acid and/or oil obtainable by the method comprising (i) maintaining a cell suspension culture of oil-producing plant cells under conditions such that the cultured cells synthesise and secrete at least one fatty acid and/or oil into the cell suspension culture medium; and (ii) extracting the thus secreted at least one fatty acid and/or oil from the cell suspension culture medium. The present invention also relates to a product comprising the extract, such as a food product, cosmetic, or lubricant, and to a biofuel obtainable by the further processing and conversion of the extract of at least one fatty acid and/or oil. The present invention further relates to a cell suspension culture of oil-producing plant cells comprising an inhibitor of fatty acid glyceration, the use of the cell suspension culture to produce at least one fatty acid, and to a plant cell suspension culture medium comprising an inhibitor of fatty acid glyceration. Additionally, the present invention relates to a method for producing biofuels from at least one fatty acid and/or mono-, di- and/or tri-glycerides comprising reacting a first volume of the at least one fatty acid and/or mono-, di- and/or tri-glycerides with a second volume of a reactant selected from an alcohol, alkane or alkene, in the presence of a base catalyst, thereby to form the biofuel, wherein the ratio of first volume to second volume is greater than 1:6, such as at least 1:5, 1:4, 1:3, 1:2, or 1:1.
摘要翻译：本发明涉及通过以下方法获得的至少一种脂肪酸和/或油的提取物，所述方法包括（i）在产生培养的细胞合成并分泌至少一种脂肪的条件下保持产油植物细胞的细胞悬浮培养物酸和/或油注入细胞悬液培养基中; 和（ii）从细胞悬浮培养基中提取如此分泌的至少一种脂肪酸和/或油。本发明还涉及包含提取物（例如食品，化妆品或润滑剂）的产品，并涉及通过进一步加工和转化至少一种脂肪酸和/或油的提取物可获得的生物燃料。本发明进一步涉及包含脂肪酸甘油化抑制剂的产油植物细胞的细胞悬浮培养物，使用细胞悬浮培养物产生至少一种脂肪酸，以及涉及包含抑制剂的植物细胞悬浮培养基的脂肪酸甘油酯。另外，本发明涉及由至少一种脂肪酸和/或甘油单酯，甘油二酯和/或甘油三酯制备生物燃料的方法，包括使第一体积的至少一种脂肪酸和/或单 - ，二 - 和/ 二 - 和/或三 - 甘油酯与第二体积的选自醇，烷烃或烯烃的反应物在碱催化剂存在下反应，从而形成生物燃料，其中第一体积与第二体积的比率大于 1：6，例如至少1：5,1：4,1：3,1：2或1：1。

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