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1. 发明公开

EP2938367A1 METHODS, COMPOSITIONS AND KITS FOR SURGICAL REPAIR 有权转让
标题翻译： VERFAHREN，ZUSAMMENSETZUNGEN UND KITSFÜRCHIRCHGISCHE REPARATUR
公开(公告)号：EP2938367A1
公开(公告)日：2015-11-04
申请号：EP13824260.7
申请日：2013-12-23
申请人： Boston Scientific Scimed, Inc. , Nagale, Sandra , Boden, Mark, W. , Dolan, Andrew
发明人： The designation of the inventor has not yet been filed
IPC分类号： A61L27/52 , A61L27/54
CPC分类号： A61L31/16 , A61K9/0034 , A61L27/52 , A61L27/54 , A61L31/042 , A61L31/044 , A61L31/045 , A61L31/047 , A61L31/048 , A61L31/06 , A61L31/145 , A61L2400/06
摘要： In some aspects, the present invention provides surgical procedures that comprise applying compositions into and/or onto tissue, including supporting tissues (e.g., ligaments, connective tissue, muscles, etc.) for pelvic organs, among other tissues. In other aspects, the present disclosure pertains to compositions that are useful for performing such procedures. In still other aspects, the present disclosure pertains to kits that are useful for performing such procedures.
摘要翻译：在一些方面，本发明提供包括将组合物施加到组织中和/或组织上的外科手术，包括用于盆腔器官的支撑组织（例如韧带，结缔组织，肌肉等）等组织。在其他方面，本公开涉及可用于进行这些程序的组合物。在另外的方面，本公开涉及可用于执行这种程序的试剂盒。

2. 发明专利

AU2013370469A1 Methods, compositions and kits for surgical repair 未知
公开(公告)号：AU2013370469A1
公开(公告)日：2015-04-16
申请号：AU2013370469
申请日：2013-12-23
申请人： DOLAN ANDREW , NAGALE SANDRA , BODEN MARK , BOSTON SCIENT SCIMED INC
发明人： NOT GIVEN
IPC分类号： A61L27/52 , A61L27/54
摘要： In some aspects, the present invention provides surgical procedures that comprise applying compositions into and/or onto tissue, including supporting tissues (e.g., ligaments, connective tissue, muscles, etc.) for pelvic organs, among other tissues. In other aspects, the present disclosure pertains to compositions that are useful for performing such procedures. In still other aspects, the present disclosure pertains to kits that are useful for performing such procedures.

3. 发明公开

EP1960748A4 METHOD AND SYSTEM OF ARRAY IMAGING 审中-公开
标题翻译：方法和系统阵成像
公开(公告)号：EP1960748A4
公开(公告)日：2012-05-02
申请号：EP06851638
申请日：2006-08-21
申请人： UNIV TUFTS , BENCIC NAGALE SANDRA
发明人： WALT DAVID R
IPC分类号： G01J3/30 , G01N21/76 , H01J3/14
CPC分类号： G01J3/2803 , G01J3/02 , G01J3/0213 , G01J3/0229 , G01J3/10 , G01J3/4406 , G01J2001/0276 , G01N21/6428 , G01N21/6458 , G01N2021/6441 , G01N2021/6484 , G01N2201/08 , G01N2201/088

4. 发明公开

EP2816948A1 IMAGING DEVICE AND METHODS OF USING THE SAME 审中-公开
标题翻译：成像装置及其使用方法
公开(公告)号：EP2816948A1
公开(公告)日：2014-12-31
申请号：EP13708578.3
申请日：2013-02-21
申请人： Boston Scientific Scimed, Inc. , Nagale, Sandra
发明人： NAGALE, Sandra
IPC分类号： A61B1/06 , A61B1/07 , A61B5/00
CPC分类号： A61B5/0084 , A61B1/00165 , A61B1/0623 , A61B1/0638 , A61B1/07 , A61B5/0035 , A61B5/0075 , A61B5/6885 , A61B5/6886 , A61B2562/0238
摘要： In one embodiment, a medical device includes a first optical fiber, a second optical fiber, a third optical fiber, and a fourth optical fiber. The first optical fiber is operatively coupled to a first electromagnetic radiation source and is configured to transmit electromagnetic radiation to bodily tissue. The second optical fiber is configured to receive electromagnetic radiation from the first electromagnetic radiation source scattered by the bodily tissue. The third optical fiber is operatively coupled to a second electromagnetic radiation source and is configured to transmit electromagnetic radiation to bodily tissue. The second electromagnetic radiation source is different than the first electromagnetic radiation source. The fourth optical fiber is configured to receive electromagnetic radiation from the second electromagnetic radiation source scattered by the bodily tissue.

5. 发明公开

EP1960748A2 METHOD AND SYSTEM OF ARRAY IMAGING 审中-公开
标题翻译：方法和系统阵成像
公开(公告)号：EP1960748A2
公开(公告)日：2008-08-27
申请号：EP06851638.4
申请日：2006-08-21
申请人： TUFTS UNIVERSITY , Bencic-Nagale, Sandra
发明人： WALT, David R.
IPC分类号： G01J1/32 , H01J40/14
CPC分类号： G01J3/2803 , G01J3/02 , G01J3/0213 , G01J3/0229 , G01J3/10 , G01J3/4406 , G01J2001/0276 , G01N21/6428 , G01N21/6458 , G01N2021/6441 , G01N2021/6484 , G01N2201/08 , G01N2201/088
摘要： The present invention relates to a method and system of array imaging that extends or maximizes the longevity of the sensor array b minimizing the effects of photobleaching. The imaging system has a light source (12), a variable exposure aperture (14), and a varia filter system (16). The system extends the longevity of sensors (28) by 1) using the variable exposure aperture to selectively expose sections of the sensor array containing representative numbers of each type of sensor, and/or 2) using the variable filter system to control the intensity of the excitation light, providing only the intensity required to induce the appropriate excitation and increasing intensity over time as necessary to counteract the effects of photobleaching.

6. 发明申请

WO2013119830A1 SURGICAL SCAFFOLDS 审中-公开
标题翻译：外科手术
公开(公告)号：WO2013119830A1
公开(公告)日：2013-08-15
申请号：PCT/US2013/025171
申请日：2013-02-07
申请人： BOSTON SCIENTIFIC SCIMED, INC. , NAGALE, Sandra , BODEN, Mark W.
发明人： NAGALE, Sandra , BODEN, Mark W.
IPC分类号： A61L27/50 , A61L31/14 , A61F2/00
CPC分类号： A61F2/0063 , A61F2/0045 , A61F2230/006 , A61L31/06 , A61L31/146 , A61L31/16 , A61L2300/43 , A61L2430/30 , A61L2430/34 , F04C2270/041 , C08L75/04
摘要： According to an aspect of the present invention, surgical scaffolds for soft tissue repair are provided. The surgical scaffolds comprise a sheet of a material within which through-holes are formed. Further aspects of the invention, among others, pertain to methods of using such surgical scaffolds and to kits containing such surgical scaffolds.
摘要翻译：根据本发明的一个方面，提供了用于软组织修复的手术支架。手术支架包括形成通孔的材料片。本发明的其它方面以及其它方面涉及使用这种手术支架的方法和含有这种手术支架的试剂盒。

7. 发明申请

WO2013126576A1 IMAGING DEVICE AND METHODS OF USING THE SAME 审中-公开
标题翻译：成像装置及其使用方法
公开(公告)号：WO2013126576A1
公开(公告)日：2013-08-29
申请号：PCT/US2013/027143
申请日：2013-02-21
申请人： BOSTON SCIENTIFIC SCIMED, INC. , NAGALE, Sandra
发明人： NAGALE, Sandra
IPC分类号： A61B1/06 , A61B1/07 , A61B5/00
CPC分类号： A61B5/0084 , A61B1/00165 , A61B1/0623 , A61B1/0638 , A61B1/07 , A61B5/0035 , A61B5/0075 , A61B5/6885 , A61B5/6886 , A61B2562/0238
摘要： In one embodiment, a medical device includes a first optical fiber, a second optical fiber, a third optical fiber, and a fourth optical fiber. The first optical fiber is operatively coupled to a first electromagnetic radiation source and is configured to transmit electromagnetic radiation to bodily tissue. The second optical fiber is configured to receive electromagnetic radiation from the first electromagnetic radiation source scattered by the bodily tissue. The third optical fiber is operatively coupled to a second electromagnetic radiation source and is configured to transmit electromagnetic radiation to bodily tissue. The second electromagnetic radiation source is different than the first electromagnetic radiation source. The fourth optical fiber is configured to receive electromagnetic radiation from the second electromagnetic radiation source scattered by the bodily tissue.
摘要翻译：在一个实施例中，医疗装置包括第一光纤，第二光纤，第三光纤和第四光纤。第一光纤可操作地耦合到第一电磁辐射源并且被配置为将电磁辐射传输到身体组织。第二光纤被配置为接收来自由身体组织散射的第一电磁辐射源的电磁辐射。第三光纤可操作地耦合到第二电磁辐射源，并且被配置为将电磁辐射传输到身体组织。第二电磁辐射源与第一电磁辐射源不同。第四光纤被配置为从由身体组织散射的第二电磁辐射源接收电磁辐射。

8. 发明申请

WO2008048698A2 CHEMICAL SWITCHES FOR DETECTING REACTIVE CHEMICAL AGENTS 审中-公开
标题翻译：用于检测活性化学试剂的化学开关
公开(公告)号：WO2008048698A2
公开(公告)日：2008-04-24
申请号：PCT/US2007/062568
申请日：2007-02-22
申请人： TRUSTEES OF TUFTS COLLEGE , WALT, David, R. , BENCIC-NAGALE, Sandra
发明人： WALT, David, R. , BENCIC-NAGALE, Sandra
IPC分类号： C07D215/02
CPC分类号： G01N33/0057 , C07D219/06 , G01N21/643 , Y10T436/16 , Y10T436/163333
摘要： Certain embodiments of the present invention relate to the preparation of microbeads that exhibit a "turn on" fluorescence response within seconds of exposure to an analyte vapor (e.g., a chemical warfare agent or a reactive stimulant). This sensing approach is modeled after the mechanism for inhibition of acetylcholinesterase enzyme activity, and utilizes a specific and irreversible reaction between phosphonyl halides and a fluorescent indicator. The present invention also relates to a sensor and a method for sensing an analyte through detection of changes in the fluorescing properties of the inventive microbeads.
摘要翻译：本发明的某些实施方案涉及制备显示“开启”的微珠，在暴露于分析物蒸汽（例如化学战剂或反应性兴奋剂）的秒内的荧光响应。这种传感方法模仿抑制乙酰胆碱酯酶活性的机制，并利用膦酰卤和荧光指示剂之间的特异性和不可逆反应。本发明还涉及用于通过检测本发明的微珠的荧光性质的变化来感测分析物的传感器和方法。

9. 发明申请

WO2017024135A1 SMART DEVICE FOR BLADDER MAPPING 审中-公开
标题翻译：用于刀片映射的SMART设备
公开(公告)号：WO2017024135A1
公开(公告)日：2017-02-09
申请号：PCT/US2016/045555
申请日：2016-08-04
申请人： BOSTON SCIENTIFIC SCIMED, INC. , NAGALE, Sandra , SHOME, Shibaji , HARRAH, Timothy , BODEN, Mark , SHUROS, Allan , CLARK, Bryan , CHIAVETTA, Amedeo , SWANSON, Lynne , WEMER, Dennis
发明人： NAGALE, Sandra , SHOME, Shibaji , HARRAH, Timothy , BODEN, Mark , SHUROS, Allan , CLARK, Bryan , CHIAVETTA, Amedeo , SWANSON, Lynne , WEMER, Dennis
IPC分类号： A61B5/20 , A61B5/00 , A61B5/053 , A61B5/107
CPC分类号： A61B5/202 , A61B1/00045 , A61B1/04 , A61B1/07 , A61B1/307 , A61B5/04882 , A61B5/0538 , A61B5/1076 , A61B5/20 , A61B5/205 , A61B5/4836 , A61B5/6852 , A61B5/6853 , A61B5/6858 , A61B5/6874 , A61B5/6885 , A61B5/74 , A61B18/1492 , A61B2018/0022 , A61B2018/00267 , A61B2018/00517 , A61B2018/00577 , A61B2562/166 , A61N1/36007
摘要： Systems, devices and methods for the treatment of bladder conditions using bladder visualization without the need for optical elements and for subsequent direct electrical pacing are provided. The systems, devices and methods generally apply pacing stimulus directly to the bladder wall, from one or more of the inner and outer bladder surfaces.
摘要翻译：提供了使用膀胱可视化治疗膀胱状况的系统，装置和方法，而不需要光学元件和随后的直接起搏。系统，装置和方法通常将起搏刺激直接从膀胱壁的一个或多个施加到膀胱壁上。

10. 发明申请

WO2014164333A2 IMPLANTABLE MEDICAL DEVICE AND METHODS OF DELIVERING THE IMPLANTABLE MEDICAL DEVICE 审中-公开
标题翻译：可植入医疗装置和递送可植入医疗装置的方法
公开(公告)号：WO2014164333A2
公开(公告)日：2014-10-09
申请号：PCT/US2014021957
申请日：2014-03-07
申请人： BOSTON SCIENT SCIMED INC , PALMISANO BRENT , NAGALE SANDRA , BODEN MARK W , HARRAH TIMOTHY P , LI JAMIE
发明人： PALMISANO BRENT , NAGALE SANDRA , BODEN MARK W , HARRAH TIMOTHY P , LI JAMIE
IPC分类号： A61F2/00
CPC分类号： A61F2/0063 , A61B2017/06052 , A61B2017/06176 , A61F2/0045 , A61F2002/0072 , A61F2220/0016 , A61F2230/006
摘要： In one general aspect, an apparatus can include a mesh having an edge, a loop coupled to the edge of the mesh, and a suture coupled to at least one of the loop or the edge of the mesh, the suture having a barb. The loop can have an inner diameter smaller than a combined width of the suture and at least a portion of an outer portion of the barb.
摘要翻译：在一个一般方面，装置可以包括具有边缘的网，耦合到网的边缘的环以及联接到网的环或边缘中的至少一个的缝线，缝合线具有倒钩。该环可以具有小于缝合线的组合宽度和倒钩的外部部分的至少一部分的内径。

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