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1. 发明申请

US20070097494A1 Objective lens unit, objective lens insertion tool, microscope, objective optical system fixing device, and microscope system 审中-公开
标题翻译：物镜单元，物镜插入工具，显微镜，物镜光学系统固定装置和显微镜系统
公开(公告)号：US20070097494A1
公开(公告)日：2007-05-03
申请号：US11642436
申请日：2006-12-20
申请人： Kazunari Tokuda , Akihiro Horii , Yoshiyuki Kumada , Mitsuhiro Hara , Tadashi Hirata , Hiroya Fukuyama
发明人： Kazunari Tokuda , Akihiro Horii , Yoshiyuki Kumada , Mitsuhiro Hara , Tadashi Hirata , Hiroya Fukuyama
IPC分类号： G02B21/00
CPC分类号： G02B21/26 , G02B23/2476
摘要： The invention aims to make it unnecessary to reposition an objective lens when repeatedly carrying out examinations. It is possible to carry out in vivo examination of tissue such as cells and muscle tissue or various internal organs, such as the heart, liver, and so forth, of mammals, especially small experimental animals, over a comparatively long period of time. A microscope system having an objective optical system unit and a structure or member for fixing the objective optical system unit to a living body is provided.
摘要翻译：本发明的目的是在重复执行检查时不需要重新定位物镜。可以在比较长的时间内对哺乳动物，特别是小型实验动物等细胞，肌肉组织或各种内部器官（如心脏，肝脏等）的组织进行体内检查。提供了一种具有物镜光学系统单元和用于将物镜光学系统单元固定到生物体的结构或构件的显微镜系统。

2. 发明申请

US20080130103A1 Optical-Scanning Microscope Examination Apparatus 有权
标题翻译：光学扫描显微镜检查仪器
公开(公告)号：US20080130103A1
公开(公告)日：2008-06-05
申请号：US11628762
申请日：2005-06-09
申请人： Mitsuhiro Hara , Hiroshi Tosaka , Akihiro Horii , Yoshihisa Tanikawa
发明人： Mitsuhiro Hara , Hiroshi Tosaka , Akihiro Horii , Yoshihisa Tanikawa
IPC分类号： G02B21/06
CPC分类号： G02B21/22 , A61B5/0059 , A61B5/0068 , A61B2503/40 , G02B21/0036
摘要： A clear image having suppressed blurring due to pulsing is obtained by in-vivo examination of biological tissue or various internal organs of mammals, including small laboratory animals. The invention provides an optical-scanning microscope examination apparatus including a light source; a light-transmitting member for transmitting light from the light source; a collimator optical system for converting the transmitted light to a collimated beam; a beam-scanning unit for scanning the collimated beam on a subject; a focusing optical system for focusing the scanned beam onto the subject; a pupil-projection optical system; a light detector for detecting return light returning from the subject via the focusing optical system, the pupil-projection optical system, the beam-scanning unit, the collimator optical system, and the light-transmitting member; an actuator for moving the collimator optical system in an optical-axis direction; a control apparatus for controlling driving thereof; and a deflecting mechanism for deflecting the light issuing from the light-transmitting member in a direction intersecting the optical axis thereof, wherein the actuator is disposed in a space parallel to a plane including optical axes before and after deflection by the deflecting mechanism.
摘要翻译：通过对包括小实验室动物在内的哺乳动物的生物组织或各种内部器官的体内检查来获得抑制由于脉冲引起的模糊的清晰图像。本发明提供一种包括光源的光学扫描显微镜检查装置; 用于从光源透射光的透光构件; 用于将透射光转换成准直光束的准直器光学系统; 用于扫描被摄体上的准直光束的光束扫描单元; 用于将扫描光束聚焦到被摄体上的聚焦光学系统; 瞳孔投影光学系统; 光检测器，用于检测从对象经由聚焦光学系统，瞳孔投影光学系统，光束扫描单元，准直仪光学系统和透光元件返回的返回光; 用于沿准直光学系统沿光轴方向移动的致动器; 用于控制其驱动的控制装置; 以及偏转机构，用于偏转从所述透光部件发出的光沿与其光轴相交的方向，其中所述致动器设置在与所述偏转机构偏转前后包括光轴的平面平行的空间中。

3. 发明授权

US07283247B2 Optical probe system 有权
标题翻译：光探头系统
公开(公告)号：US07283247B2
公开(公告)日：2007-10-16
申请号：US10667773
申请日：2003-09-22
申请人： Atsushi Okawa , Akihiro Horii , Tianyu Xie , Mitsuhiro Hara
发明人： Atsushi Okawa , Akihiro Horii , Tianyu Xie , Mitsuhiro Hara
IPC分类号： G01B9/02
CPC分类号： A61B1/00045 , A61B1/00009 , A61B1/00096 , A61B1/00172 , A61B1/04 , A61B5/0066 , A61B5/0084 , A61B5/7232 , G02B21/365 , G02B23/2484 , G06T5/009 , G06T5/40
摘要： An optical probe system comprises an optical probe that is inserted into a body cavity, a light source that generates light which is irradiated to an object, and a high-magnification observation unit included in the distal section of the optical probe. The optical probe system further comprises: an image digitization unit that digitizes a luminance signal produced by the high-magnification observation unit; an image parameter sampling unit that samples an image parameter from an image; an optimization parameter calculation unit that calculates an optimization parameter on the basis of the image parameter; an image optimization unit that optimizes an image according to the optimization parameter; an image display device on which an optimized image is displayed; and a digital image preservation unit in which a digitized image is preserved.
摘要翻译：光探头系统包括插入体腔的光学探针，产生照射到物体的光的光源和包括在光学探针的远端部分中的高倍率观察单元。光探头系统还包括：数字化由高倍率观察单元产生的亮度信号的图像数字化单元; 图像参数取样单元，对来自图像的图像参数进行采样; 优化参数计算单元，其基于所述图像参数计算优化参数; 图像优化单元，其根据优化参数优化图像; 显示优化图像的图像显示装置; 以及保存数字化图像的数字图像保存单元。

4. 发明授权

US07158234B2 Optical scanning observation apparatus 有权
标题翻译：光学扫描观察装置
公开(公告)号：US07158234B2
公开(公告)日：2007-01-02
申请号：US10808857
申请日：2004-03-25
申请人： Akio Uchiyama , Akihiro Horii , Shuhei Iizuka , Tadashi Hirata , Mitsuhiro Hara , Yoshiyuki Kumada , Kazunari Tokuda
发明人： Akio Uchiyama , Akihiro Horii , Shuhei Iizuka , Tadashi Hirata , Mitsuhiro Hara , Yoshiyuki Kumada , Kazunari Tokuda
IPC分类号： G01B9/02 , G01B11/02
CPC分类号： A61B1/07 , A61B1/0008 , A61B1/00165 , A61B1/00172 , A61B1/00183 , A61B5/0066 , A61B5/0084 , B82Y35/00 , G01B9/02002 , G01B9/0205 , G01B9/02064 , G01B9/02091 , G01B2290/35 , G01N21/474 , G01N21/4795
摘要： Before performing observation with an optical scanning probe using a low-coherence light source and the like, a shutter is inserted in a reference light side optical path to create a state wherein interference light does not occur, in which state a reference member is set to a focal position of a converging optical system such that the output of a light detector is maximal by moving the reference member by a driving device at an observation light optical path side of an optical scanning probe, following which the shutter is opened, and the position of a mirror at the reference light side is moved and set such that the output of the light detecting means is maximal, thereby enabling the optical scanning observation apparatus to be set to a state of suitable optical properties, easily and smoothly.
摘要翻译：在使用低相干光源等的光学扫描探针进行观察之前，将快门插入参考光侧光路中以产生不发生干涉光的状态，在该状态下将基准部件设置为会聚光学系统的焦点位置，使得光检测器的输出通过在光扫描探针的观察光光路侧处的驱动装置移动参考构件而最大化，随后开启快门，位置在参考光侧的反射镜的移动和设置使得光检测装置的输出最大，从而使光学扫描观察装置能够容易且平稳地设置为适当的光学特性的状态。

5. 发明授权

US07154084B2 Optical-scanning microscope apparatus 有权
标题翻译：光学扫描显微镜装置
公开(公告)号：US07154084B2
公开(公告)日：2006-12-26
申请号：US11175619
申请日：2005-07-06
申请人： Mitsuhiro Hara
发明人： Mitsuhiro Hara
IPC分类号： G02B27/40
CPC分类号： G02B26/105 , G02B21/002
摘要： Compact design is achieved to minimize blocking of the field of view of a stereomicroscope apparatus. Furthermore, astigmatism is decreased to produce a high-quality image. An optical-scanning microscope apparatus includes a light source, a light-transmitting member for transmitting light from the light source, an apparatus main body for illuminating a subject with the light transmitted by the light-transmitting member, and a photodetector for detecting return light returning from the subject via the apparatus main body and the light-transmitting member. The apparatus main body includes a collimating optical system for converting the light transmitted by the light-transmitting member into collimated light, a scanning mirror for deflecting the collimated light emitted from the collimating optical system at a deflection angle smaller than 90° to scan the light over the subject, a focusing optical system for focusing the light scanned by the scanning mirror onto the subject, and a pupil-projection optical system disposed between the focusing optical system and the above-described scanning mirror.
摘要翻译：实现了紧凑的设计，以使立体显微镜装置的视场的阻挡最小化。此外，散光减少以产生高质量的图像。一种光学扫描显微镜装置，包括光源，用于透射来自光源的光的透光构件，用透光构件透射的光照射被摄体的装置主体，以及用于检测返回光的光检测器通过设备主体和透光部件从被摄体返回。该装置主体包括：准直光学系统，用于将由透光构件透射的光转换为准直光;扫描镜，用于以小于90°的偏转角偏转从准直光学系统发射的准直光，以扫描光在该对象上，用于将由扫描镜扫描的光聚焦到被摄体上的聚焦光学系统和设置在聚焦光学系统和上述扫描反射镜之间的瞳孔投影光学系统。

6. 发明申请

US20060118710A1 Optical-scanning microscope apparatus 有权
公开(公告)号：US20060118710A1
公开(公告)日：2006-06-08
申请号：US11175619
申请日：2005-07-06
申请人： Mitsuhiro Hara
发明人： Mitsuhiro Hara
IPC分类号： H01J3/14
CPC分类号： G02B26/105 , G02B21/002
摘要： Compact design is achieved to minimize blocking of the field of view of a stereomicroscope apparatus. Furthermore, astigmatism is decreased to produce a high-quality image. An optical-scanning microscope apparatus includes a light source, a light-transmitting member for transmitting light from the light source, an apparatus main body for illuminating a subject with the light transmitted by the light-transmitting member, and a photodetector for detecting return light returning from the subject via the apparatus main body and the light-transmitting member. The apparatus main body includes a collimating optical system for converting the light transmitted by the light-transmitting member into collimated light, a scanning mirror for deflecting the collimated light emitted from the collimating optical system at a deflection angle smaller than 90° to scan the light over the subject, a focusing optical system for focusing the light scanned by the scanning mirror onto the subject, and a pupil-projection optical system disposed between the focusing optical system and the above-described scanning mirror.

7. 发明授权

US4852932A Container device used in a vehicle 失效
标题翻译：在车辆中使用的集装箱装置
公开(公告)号：US4852932A
公开(公告)日：1989-08-01
申请号：US119858
申请日：1987-11-12
申请人： Seiji Komeya , Mitsuhiro Hara
发明人： Seiji Komeya , Mitsuhiro Hara
IPC分类号： B60N3/12
CPC分类号： B60N3/12
摘要： A container device used in a vehicle includes a retainer, a box, a power source for driving the box and a driving force transmission. The power source is provided on a back portion of the box itself or a back portion of the retainer as viewed along the direction of movement of the box. In the device the portion which has been a dead space in a conventional device is effectively utilized as a location of the power source. The device is constituted small-sized as a whole and the outer shape of the entire device is simplified.
摘要翻译：在车辆中使用的集装箱装置包括保持器，箱体，用于驱动箱的动力源和驱动力传递装置。电源设置在盒本身的后部或者沿着盒的移动方向观察时的保持器的后部。在设备中，常规设备中已经是死区的部分被有效地用作电源的位置。该装置整体尺寸小，整体装置的外形简化。

8. 发明授权

US07852551B2 Optical-scanning microscope examination apparatus 有权
标题翻译：光学扫描显微镜检查仪
公开(公告)号：US07852551B2
公开(公告)日：2010-12-14
申请号：US11628762
申请日：2005-06-09
申请人： Mitsuhiro Hara , Hiroshi Tosaka , Akihiro Horii , Kazunari Tokuda , Yoshihisa Tanikawa
发明人： Mitsuhiro Hara , Hiroshi Tosaka , Akihiro Horii , Kazunari Tokuda , Yoshihisa Tanikawa
IPC分类号： G02B21/00
CPC分类号： G02B21/22 , A61B5/0059 , A61B5/0068 , A61B2503/40 , G02B21/0036
摘要： A clear image having suppressed blurring due to pulsing is obtained by in-vivo examination of biological tissue or various internal organs of mammals, including small laboratory animals. The invention provides an optical-scanning microscope examination apparatus including a light source; a light-transmitting member for transmitting light from the light source; a collimator optical system for converting the transmitted light to a collimated beam; a beam-scanning unit for scanning the collimated beam on a subject; a focusing optical system for focusing the scanned beam onto the subject; a pupil-projection optical system; a light detector for detecting return light returning from the subject via the focusing optical system, the pupil-projection optical system, the beam-scanning unit, the collimator optical system, and the light-transmitting member; an actuator for moving the collimator optical system in an optical-axis direction; a control apparatus for controlling driving thereof; and a deflecting mechanism for deflecting the light issuing from the light-transmitting member in a direction intersecting the optical axis thereof, wherein the actuator is disposed in a space parallel to a plane including optical axes before and after deflection by the deflecting mechanism.
摘要翻译：通过对包括小实验室动物在内的哺乳动物的生物组织或各种内部器官的体内检查来获得抑制由于脉冲引起的模糊的清晰图像。本发明提供一种包括光源的光学扫描显微镜检查装置; 用于从光源透射光的透光构件; 用于将透射光转换成准直光束的准直器光学系统; 用于扫描被摄体上的准直光束的光束扫描单元; 用于将扫描光束聚焦到被摄体上的聚焦光学系统; 瞳孔投影光学系统; 光检测器，用于检测从对象经由聚焦光学系统，瞳孔投影光学系统，光束扫描单元，准直仪光学系统和透光元件返回的返回光; 用于沿准直光学系统沿光轴方向移动的致动器; 用于控制其驱动的控制装置; 以及偏转机构，用于偏转从所述透光部件发出的光沿与其光轴相交的方向，其中所述致动器设置在与所述偏转机构偏转前后包括光轴的平面平行的空间中。

9. 发明申请

US20050094260A1 Objective lens unit, objective lens insertion tool, microscope, objective optical system fixing device, and microscope system 审中-公开
标题翻译：物镜单元，物镜插入工具，显微镜，物镜光学系统固定装置和显微镜系统
公开(公告)号：US20050094260A1
公开(公告)日：2005-05-05
申请号：US10964866
申请日：2004-10-14
申请人： Kazunari Tokuda , Akihiro Horii , Yoshiyuki Kumada , Mitsuhiro Hara , Tadashi Hirata , Hiroya Fukuyama
发明人： Kazunari Tokuda , Akihiro Horii , Yoshiyuki Kumada , Mitsuhiro Hara , Tadashi Hirata , Hiroya Fukuyama
IPC分类号： G02B21/26 , G02B23/24 , G02B21/00
CPC分类号： G02B21/26 , G02B23/2476
摘要： The invention aims to make it unnecessary to reposition an objective lens when repeatedly carrying out examinations. It is possible to carry out in vivo examination of tissue such as cells and muscle tissue or various internal organs, such as the heart, liver, and so forth, of mammals, especially small experimental animals, over a comparatively long period of time. A microscope system having an objective optical system unit and a structure or member for fixing the objective optical system unit to a living body is provided.
摘要翻译：本发明的目的是在重复执行检查时不需要重新定位物镜。可以在比较长的时间内对哺乳动物，特别是小型实验动物等细胞，肌肉组织或各种内部器官（如心脏，肝脏等）的组织进行体内检查。提供了一种具有物镜光学系统单元和用于将物镜光学系统单元固定到生物体的结构或构件的显微镜系统。

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