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1. 发明授权

US10368777B2 Non-contrast dynamic MRI myocardial perfusion analysis and visualization 有权
公开(公告)号：US10368777B2
公开(公告)日：2019-08-06
申请号：US13618001
申请日：2012-09-14
申请人： Xiangzhi Zhou , Mitsue Miyazaki , Tsutomu Hoshino
发明人： Xiangzhi Zhou , Mitsue Miyazaki , Tsutomu Hoshino
IPC分类号： A61B5/00 , A61B5/026 , A61B5/055 , G01R33/56 , G01R33/385 , G01R33/483 , G01R33/563
摘要： Black blood time to inversion (BBTI) tag-on and tag-off images acquired by magnetic resonance imaging (MRI) are analyzed to produce difference magnitude 3D images as a function of time (BBTI values) representing blood perfusion in a region of interest (ROI). Perfusion data of the ROI having values which are different for normal and abnormal myocardial tissues are displayed for plural slices of a 3D image and for plural BBTI values in a single display panel.

2. 发明授权

US09134394B2 Magnetic resonance imaging apparatus and image processing apparatus 有权
标题翻译：磁共振成像装置和图像处理装置
公开(公告)号：US09134394B2
公开(公告)日：2015-09-15
申请号：US11896941
申请日：2007-09-06
申请人： Mitsue Miyazaki
发明人： Mitsue Miyazaki
IPC分类号： A61B5/05 , G01R33/563 , A61B5/055 , A61B5/00 , G01R33/483 , G01R33/567 , G01R33/561
CPC分类号： A61B5/0263 , A61B5/004 , A61B5/0044 , A61B5/0402 , A61B5/055 , A61B5/7285 , G01R33/4835 , G01R33/4838 , G01R33/5611 , G01R33/5635 , G01R33/5673
摘要： A magnetic resonance imaging apparatus includes a first data acquisition unit, a second data acquisition unit and an image data generating unit. The first data acquisition unit acquires first data from a slice to be a target after a first delay time from a reference of a first heart rate in synchronization with an electrocardiogram. The second data acquisition unit acquires second data from the slice after a second delay time from a reference of a second heart rate which is different from the first heart rate. The image data generating unit generates image data with image reconstruction processing using the first data and the second data.
摘要翻译：磁共振成像装置包括第一数据获取单元，第二数据获取单元和图像数据生成单元。第一数据获取单元从与心电图同步的第一心率的参考的第一延迟时间之后从切片获取第一数据作为目标。第二数据获取单元从与第一心率不同的第二心率的参考的第二延迟时间之后从切片获取第二数据。图像数据生成单元使用第一数据和第二数据生成具有图像重构处理的图像数据。

3. 发明申请

US20140062474A1 ENHANCED FAT SATURATION IN MYOCARDIAL INFARCTION MRI 有权
标题翻译：心肌梗死MRI增强脂肪饱和度
公开(公告)号：US20140062474A1
公开(公告)日：2014-03-06
申请号：US13598435
申请日：2012-08-29
申请人： Xiangzhi ZHOU , Mitsue MIYAZAKI
发明人： Xiangzhi ZHOU , Mitsue MIYAZAKI
IPC分类号： G01R33/56 , G01R33/34
CPC分类号： A61B5/055 , A61B5/0044 , G01R33/5607
摘要： MRI k-space data is acquired for a patient ROI during data acquisition sequences including a nuclear magnetic resonance (NMR) signal readout period using a late gadolinium enhanced (LGE) data acquisition sequence including at least one fat-specific RF NMR magnetization inversion pulse imposed (a) after a water-specific RF NMR magnetization inversion pulse timed to cause a substantial null in NMR magnetization of normal tissue protons near a center of the readout period and (b) before the readout period center, which fat-specific inversion pulse is also timed to cause a substantial null in NMR magnetization of fat tissue protons near the readout period center. The acquired MR image data is reconstructed into a contrast enhanced LGE image of tissues within the ROI but having substantially suppressed normal and fat components therein.
摘要翻译：在包括使用晚期钆增强（LGE）数据采集序列的核磁共振（NMR）信号读出周期的数据采集序列的数据采集序列期间获取MRI k空间数据，其包括至少一个脂肪特异性RF NMR磁化反转脉冲（a）在水特异性RF核磁共振磁化反转脉冲之后，定时地使读出周期中心附近的正常组织质子的NMR磁化大致为零，和（b）在读出周期中心之前，脂肪特异性反转脉冲也定时导致在读出周期中心附近的脂肪组织质子的NMR磁化中基本上为零。所获取的MR图像数据被重建成ROI内的组织的对比度增强的LGE图像，但是基本上抑制了其中的正常和脂肪成分。

4. 发明授权

US08581582B2 MRI non-contrast time-slip angiography using variably positioned cine sub-sequence 有权
标题翻译： MRI非造影时间流行血管造影使用可变位置的电影子序列
公开(公告)号：US08581582B2
公开(公告)日：2013-11-12
申请号：US12946549
申请日：2010-11-15
申请人： Mitsue Miyazaki
发明人： Mitsue Miyazaki
IPC分类号： G01R33/48
CPC分类号： G01R33/5635 , A61B5/0555 , G01R33/4833 , G01R33/543 , G01R33/5601 , G01R33/5608 , G01R33/56366 , G06F19/00
摘要： A magnetic resonance imaging (MRI) system using an MRI gantry and controlling computer system includes at least one programmed computer configured to effect a cardiac-triggered time-SLIP (spatial labeling inversion pulse) MRI data acquisition sequence for imaging blood perfusion in imaged patient tissue and employing therewithin an MRI cine sub-sequence. The sub-sequence is positioned in the time domain to encompass at least part of a predetermined (e.g., diastolic) cardiac time interval of the patient. Processing acquired data from the time-SLIP data acquisition sequence generates a sequence of MRI cine frame images having respectively associated different effective BBTI (black blood time to inversion) time intervals. Identifying one of the MRI cine frame images as acceptable, thereby effectively also determines an appropriate BBTI time interval for the patient. The system then outputs a time-SLIP image based on the determined appropriate BBTI time interval to at least one of (a) a display, (b) a remote system or (c) a non-transitory storage medium.
摘要翻译：使用MRI台架和控制计算机系统的磁共振成像（MRI）系统包括至少一个编程计算机，其被配置为实现用于成像的患者组织中的血液灌注成像的心脏触发时间SLIP（空间标记反转脉冲）MRI数据采集序列并在其中使用MRI电影子序列。子序列位于时域中以包含患者的预定（例如舒张期）心脏时间间隔的至少一部分。从时间SLIP数据获取序列处理获取的数据产生具有分别相关联的不同有效BBTI（黑血时间到反转）时间间隔的MRI电影帧图像序列。将MRI电影帧图像中的一个识别为可接受的，从而有效地还确定了患者适当的BBTI时间间隔。系统然后基于所确定的适当BBTI时间间隔将（a）显示器，（b）远程系统或（c）非暂时性存储介质中的至少一个输出时间SLIP图像。

5. 发明申请

US20130285655A1 APPARATUS AND METHOD FOR MAGNETIC RESONANCE IMAGING 有权
标题翻译：用于磁共振成像的装置和方法
公开(公告)号：US20130285655A1
公开(公告)日：2013-10-31
申请号：US13677716
申请日：2012-11-15
申请人： Mitsue MIYAZAKI , Hidenori TAKESHIMA , Tsutomu HOSHINO , Satoshi SUGIURA
发明人： Mitsue MIYAZAKI , Hidenori TAKESHIMA , Tsutomu HOSHINO , Satoshi SUGIURA
IPC分类号： G01R33/54 , G01R33/34
CPC分类号： G01R33/543 , G01R33/34 , G01R33/5608 , G01R33/5611 , G01R33/5614 , G01R33/56325 , G01R33/56341 , G01R33/5673
摘要： A magnetic resonance imaging apparatus includes: a sequence controlling unit that, by controlling an execution of a pulse sequence, acquires magnetic resonance (MR) signals corresponding to a plurality of channels in the pulse sequence executed as a series, the MR signals being configured to be arranged into a first region of a k-space at first intervals and into a second region larger than the first region at second intervals larger than the first intervals; an arranging unit that arranges the MR signals corresponding to the channels into the k-space as k-space data; and an image generating unit that generates first-interval k-space data corresponding to the channels based on the second-interval k-space data acquired by executing the pulse sequence and generates a magnetic resonance image based on the generated first-interval k-space data, the first-interval k-space data acquired by executing the pulse sequence, and sensitivity distributions corresponding to the channels.
摘要翻译：磁共振成像装置包括：序列控制单元，其通过控制脉冲序列的执行获取与以串行执行的脉冲序列中的多个通道对应的磁共振（MR）信号，MR信号被配置为以第一间隔被布置到k空间的第一区域中，并且以大于第一间隔的第二间隔进入比第一区域大的第二区域; 布置单元，将与所述通道相对应的MR信号布置为k空间数据; 以及图像生成单元，其基于通过执行所述脉冲序列获取的所述第二间隔k空间数据生成与所述通道对应的第一间隔k空间数据，并且基于所生成的第一间隔k空间生成磁共振图像数据，通过执行脉冲序列获取的第一间隔k空间数据，以及对应于信道的灵敏度分布。

6. 发明申请

US20120095326A1 Velocity measurement of MR-Imaged fluid flows 有权
标题翻译： MR成像流体流速测量
公开(公告)号：US20120095326A1
公开(公告)日：2012-04-19
申请号：US12923894
申请日：2010-10-13
申请人： Mitsue Miyazaki
发明人： Mitsue Miyazaki
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , A61B5/0263 , G01R33/4838 , G01R33/56308 , G01R33/5635
摘要： Velocity of MR-imaged fluid flows is measured. Data representing a measure of distance traveled by flowing fluid appearing in at least two MR images of a subject's tissue taken at different respective imaging times is generated. Data representing at least one fluid velocity measurement of the flowing fluid is generated by calculating at least one instance of distance traveled by the fluid divided by elapsed time during travel based on different respective imaging times. Data representing at least one fluid velocity measurement is then output to at least one of: (a) a display screen, (b) a non-transitory data storage medium, and (c) a remotely located site.
摘要翻译：测量MR成像流体流速。产生表示通过在不同的各个成像时间拍摄的被摄体组织的至少两个MR图像中出现的流体流动所行进的距离的量度的数据。表示流体流体的至少一个流体速度测量的数据是通过基于不同的各自的成像时间计算由流体划分的行驶距离除以行驶中的经过时间的至少一个情况而产生的。然后将代表至少一个流体速度测量的数据输出到以下中的至少一个：（a）显示屏，（b）非瞬时数据存储介质和（c）位于远处的位置。

7. 发明授权

US08131338B2 MR imaging providing tissue/blood contrast image 有权
标题翻译： MR成像提供组织/血液对比图像
公开(公告)号：US08131338B2
公开(公告)日：2012-03-06
申请号：US11819655
申请日：2007-06-28
申请人： Yoshimori Kassai , Mitsue Miyazaki , Satoshi Sugiura
发明人： Yoshimori Kassai , Mitsue Miyazaki , Satoshi Sugiura
IPC分类号： A61B5/05
CPC分类号： A61B5/055 , A61B5/0456 , A61B5/7207 , A61B5/7257 , A61B5/7285 , G01R33/4828 , G01R33/5605 , G01R33/5607 , G01R33/5615 , G01R33/5617 , G01R33/5635 , G01R33/5673
摘要： A magnetic resonance imaging (MRI) system includes an ECG detector for the patient object being imaged and an element for performing an MRI pulse sequence. An imaging unit defined by the pulse sequence is longer in temporal length than one heart beat represented by the ECG signal. An MR signal is acquired from the object in response to the pulse sequence and an MR image based on the acquired MR signal is produced. A plurality of divided MT pulses can be applied instead of the conventional single MT pulse. In this case, an SE-system pulse sequence having a shorter echo train spacing is used, to generate sounds by applying gradient pulses incorporated in an imaging pulse sequence so as to automatically instruct a patient to perform an intermittent breath hold during three-dimensional scanning.
摘要翻译：磁共振成像（MRI）系统包括用于被成像的患者物体的ECG检测器和用于执行MRI脉冲序列的元件。由脉冲序列定义的成像单元在时间长度上比由ECG信号表示的一个心跳更长。响应于脉冲序列从对象获取MR信号，并且产生基于所获取的MR信号的MR图像。可以应用多个划分的MT脉冲来代替传统的单个MT脉冲。在这种情况下，使用具有更短回波串间距的SE系统脉冲序列，通过应用结合在成像脉冲序列中的梯度脉冲来产生声音，以便在三维扫描期间自动指示患者执行间歇性呼吸。

8. 发明申请

US20110148413A1 MAGNETIC RESONANCE IMAGING APPARATUS 有权
标题翻译：磁共振成像装置
公开(公告)号：US20110148413A1
公开(公告)日：2011-06-23
申请号：US12971517
申请日：2010-12-17
申请人： Mitsue MIYAZAKI , Satoshi Sugiura
发明人： Mitsue MIYAZAKI , Satoshi Sugiura
IPC分类号： G01R33/44
CPC分类号： G01R33/5635 , G01R33/482 , G01R33/56316
摘要： A magnetic resonance imaging apparatus according to an embodiment includes a data gathering unit and an image generating unit, the data gathering unit gathers magnetic resonance data in a non-contrast manner by applying a first readout gradient pulse having a zero-order moment of 0 and a second readout gradient pulse having a zero-order moment of 0 and a first-order moment of a value different from a value of a first-order moment of the first readout gradient pulse to a region of interest including a fluid in motion, and the image generating unit periodically arranges first magnetic resonance data read out with the first readout gradient pulse and second magnetic resonance data read out with the second readout gradient pulse in at least one of a phase encoding direction and a slice encoding direction in a k-space to generate k-space data and reconstructs the k-space data to generate an image in which a fluid image and a static part image surrounding the fluid are spatially separated from each other.
摘要翻译：根据实施例的磁共振成像装置包括数据采集单元和图像生成单元，数据采集单元以非对比度方式收集磁共振数据，通过应用零阶矩为0的第一读出梯度脉冲和具有零阶矩为0的第二读出梯度脉冲和不同于第一读出梯度脉冲的一阶矩的值与包括运动中的流体的感兴趣区域的值的一阶矩，以及图像生成单元将第一读出梯度脉冲读出的第一磁共振数据和第二读出梯度脉冲读出的第二磁共振数据周期性地排列在k空间中的相位编码方向和切片编码方向中的至少一个以产生k空间数据并重建k空间数据以生成其中流体图像和围绕流体的静态部分图像在空间上分离的图像fr 彼此之间。

9. 发明申请

US20110080170A1 MRI NON-CONTRAST TIME-SLIP ANGIOGRAPHY USING VARIABLY POSITIONED CINE SUB-SEQUENCE 有权
标题翻译： MRI使用可变定位电影子序列的非对照时间滑移图
公开(公告)号：US20110080170A1
公开(公告)日：2011-04-07
申请号：US12946549
申请日：2010-11-15
申请人： Mitsue MIYAZAKI
发明人： Mitsue MIYAZAKI
IPC分类号： G01R33/48
CPC分类号： G01R33/5635 , A61B5/0555 , G01R33/4833 , G01R33/543 , G01R33/5601 , G01R33/5608 , G01R33/56366 , G06F19/00
摘要： A magnetic resonance imaging (MRI) system using an MRI gantry and controlling computer system includes at least one programmed computer configured to effect a cardiac-triggered time-SLIP (spatial labeling inversion pulse) MRI data acquisition sequence for imaging blood perfusion in imaged patient tissue and employing therewithin an MRI cine sub-sequence. The sub-sequence is positioned in the time domain to encompass at least part of a predetermined (e.g., diastolic) cardiac time interval of the patient. Processing acquired data from the time-SLIP data acquisition sequence generates a sequence of MRI cine frame images having respectively associated different effective BBTI (black blood time to inversion) time intervals. Identifying one of the MRI cine frame images as acceptable, thereby effectively also determines an appropriate BBTI time interval for the patient. The system then outputs a time-SLIP image based on the determined appropriate BBTI time interval to at least one of (a) a display, (b) a remote system or (c) a non-transitory storage medium.
摘要翻译：使用MRI台架和控制计算机系统的磁共振成像（MRI）系统包括至少一个编程计算机，其被配置为实现用于成像的患者组织中的血液灌注成像的心脏触发时间SLIP（空间标记反转脉冲）MRI数据采集序列并在其中使用MRI电影子序列。子序列位于时域中以包含患者的预定（例如舒张期）心脏时间间隔的至少一部分。从时间SLIP数据获取序列处理获取的数据产生具有分别相关联的不同有效BBTI（黑血时间到反转）时间间隔的MRI电影帧图像序列。将MRI电影帧图像中的一个识别为可接受的，从而有效地还确定患者适当的BBTI时间间隔。系统然后基于所确定的适当BBTI时间间隔将（a）显示器，（b）远程系统或（c）非暂时性存储介质中的至少一个输出时间SLIP图像。

10. 发明申请

US20100312098A1 MAGNETIC RESONANCE IMAGING APPARATUS AND IMAGE PROCESSING APPARATUS 有权
标题翻译：磁共振成像装置和图像处理装置
公开(公告)号：US20100312098A1
公开(公告)日：2010-12-09
申请号：US12857784
申请日：2010-08-17
申请人： Mitsue MIYAZAKI
发明人： Mitsue MIYAZAKI
IPC分类号： A61B5/055 , G06K9/00
CPC分类号： A61B5/0263 , A61B5/004 , A61B5/0044 , A61B5/0402 , A61B5/055 , A61B5/7285 , G01R33/4835 , G01R33/4838 , G01R33/5611 , G01R33/5635 , G01R33/5673
摘要： A magnetic resonance imaging apparatus includes a first data acquisition unit, a second data acquisition unit and an image data generating unit. The first data acquisition unit acquires first data from a slice to be a target after a first delay time from a reference of a first heart rate synchronized with an electrocardiogram. The second data acquisition unit acquires second data from the slice after a second delay time from a reference of a second heart rate which is different from the first heart rate. The image data generating unit generates image data with image reconstruction processing using the first data and the second data.
摘要翻译：磁共振成像装置包括第一数据获取单元，第二数据获取单元和图像数据生成单元。第一数据获取单元从与心电图同步的第一心率的参考的第一延迟时间之后，从切片获取第一数据作为目标。第二数据获取单元从与第一心率不同的第二心率的参考的第二延迟时间之后从切片获取第二数据。图像数据生成单元使用第一数据和第二数据生成具有图像重构处理的图像数据。

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