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    • 4. 发明授权
    • Developing unit and image forming apparatus having the same
    • 显影单元及其成像装置
    • US08600261B2
    • 2013-12-03
    • US12632205
    • 2009-12-07
    • Min Su Han
    • Min Su Han
    • G03G15/08
    • G03G21/1832G03G15/0882G03G21/181
    • Disclosed are a developing unit and an image forming apparatus having the same. The developing unit includes a partition frame provided separately from the housing of the developing unit. The partition frame is supported within the housing of the developing unit in such a manner to define a path of movement of developer within the housing through an opening formed in the partition frame. A removable sealing member is detachably arranged on the partition frame to prevent developer leakage during storage or transporting of the developing unit. The installation of the removable sealing member is made easier by the partition frame provided separately from the housing.
    • 公开了一种显影单元和具有该显影单元的图像形成装置。 显影单元包括与显影单元的壳体分开设置的分隔框架。 分隔框架以这样的方式被支撑在显影单元的壳体内,即通过形成在分隔框架中的开口限定显影剂在壳体内移动的路径。 可移除的密封构件可拆卸地布置在分隔框架上,以防止在显影单元的储存或运输期间显影剂泄漏。 通过与壳体分开设置的分隔框架,更容易地安装可拆卸的密封构件。
    • 8. 发明申请
    • Nanoparticle-Based Gene Delivery Systems
    • 基于纳米粒子的基因递送系统
    • US20110229966A1
    • 2011-09-22
    • US12809996
    • 2010-03-18
    • Min Su HanKangseok LeeDong-Eun Kim
    • Min Su HanKangseok LeeDong-Eun Kim
    • C12N5/00
    • C12N15/113A61K31/7105A61K31/713A61K47/6923C12N15/111C12N15/87C12N15/89C12N2310/11C12N2310/127C12N2310/14C12N2310/351C12N2310/51C12N2310/531C12N2320/32Y10S977/773
    • The present invention provides a gene delivery system containing nanoparticles. In more detail, the present invention provides a gene delivery system containing (a) a nanomaterial; (b) an oligonucleotide as an universal binding partner covalently linked to the surface of the nanomaterial; and (c) a cargo comprising (i) a complementary oligonucleotide containing a nucleotide sequence complementary to the universal binding partner as a binding counter-partner, and (ii) an inhibitory molecule having a nucleotide sequence complementary to a target gene of interest to be inhibited or an inducible molecule having a nucleotide sequence of a target gene of interest to be expressed. The present invention is a gene delivery system capable of feasibly deliver aptamer, siRNA, shRNA, miRNA, ribozyme, DNAzyme, PNA or gene as well as antisense oligonucleotide into the cells. In addition, the present invention is more efficient than the commercially available gene transfer reagent in respect to the degree of knockdown of target protein expression.
    • 本发明提供含有纳米颗粒的基因递送系统。 更详细地,本发明提供了一种基因递送系统,其包含(a)纳米材料; (b)与纳米材料的表面共价连接的通用结合配偶体的寡核苷酸; (c)货物,其包含(i)含有与通用结合配偶体互补的核苷酸序列作为结合对配体的互补寡核苷酸,和(ii)具有与目的靶基因互补的核苷酸序列的抑制性分子, 或具有待表达的靶基因的核苷酸序列的诱导型分子。 本发明是能够将适体,siRNA,shRNA,miRNA,核酶,DNA酶,PNA或基因以及反义寡核苷酸可行地递送到细胞中的基因递送系统。 此外,与靶蛋白质表达的敲低程度相比,本发明比市售的基因转移试剂更有效。
    • 9. 发明申请
    • DEVELOPING UNIT AND IMAGE FORMING APPARATUS HAVING THE SAME
    • 开发单位和具有该图像的图像形成装置
    • US20100158574A1
    • 2010-06-24
    • US12632205
    • 2009-12-07
    • Min Su HAN
    • Min Su HAN
    • G03G15/08
    • G03G21/1832G03G15/0882G03G21/181
    • Disclosed are a developing unit and an image forming apparatus having the same. The developing unit includes a partition frame provided separately from the housing of the developing unit. The partition frame is supported within the housing of the developing unit in such a manner to define a path of movement of developer within the housing through an opening formed in the partition frame. A removable sealing member is detachably arranged on the partition frame to prevent developer leakage during storage or transporting of the developing unit. The installation of the removable sealing member is made easier by the partition frame provided separately from the housing.
    • 公开了一种显影单元和具有该显影单元的图像形成装置。 显影单元包括与显影单元的壳体分开设置的分隔框架。 分隔框架以这样的方式被支撑在显影单元的壳体内,即通过形成在分隔框架中的开口限定显影剂在壳体内移动的路径。 可移除的密封构件可拆卸地布置在分隔框架上,以防止在显影单元的储存或运输期间显影剂泄漏。 通过与壳体分开设置的分隔框架,更容易地安装可拆卸的密封构件。