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1. 发明授权

US07227646B2 High-speed optical delay generating method by rotation reflector in optical coherence tomography and optical coherence tomography device 失效
标题翻译：光学相干断层扫描和光学相干断层扫描装置中的旋转反射器的高速光学延迟产生方法
公开(公告)号：US07227646B2
公开(公告)日：2007-06-05
申请号：US10474341
申请日：2002-04-11
申请人： Naohiro Tanno , Sumio Matsumura , Michiro Hasegawa , Yukinori Hino , Tohru Nakagawa , Masahiro Kohno
发明人： Naohiro Tanno , Sumio Matsumura , Michiro Hasegawa , Yukinori Hino , Tohru Nakagawa , Masahiro Kohno
IPC分类号： G01B9/02
CPC分类号： G01B9/02091 , G01B9/02003 , G01B2290/35 , G01N21/4795
摘要： A high-speed optical delay generating method by a rotation reflector in optical coherence tomography, capable of providing a sectional picture with a sufficiently long depth-direction (Z direction) scanning distance, and an optical coherence tomography device therefor are provided. The device comprises a low-coherence light source (1), a half mirror (2) for splitting light from the low-coherence light source (1) into two, that is, into object light towards an object (A) to be examined and reference light, a light delay mechanism (3) for delaying the reference light by means of a rotation reflector (12), a fixed mirror (4) for reflecting/returning the reference light from the light delay mechanism (3), the half-mirror (2) for combining the object light returning from the object (A) to be examined with the reference light returning from the light delay mechanism, and a light detector (11) for detecting interference light including a heterodyne interference beat signal combined at the half mirror (2).
摘要翻译：提供了一种能够提供具有足够长的深度方向（Z方向）扫描距离的截面图像和光学相干断层摄影装置的光学相干断层摄影中的旋转反射器的高速光学延迟产生方法。该装置包括低相干光源（1），用于将来自低相干光源（1）的光分成两个的半反射镜（2），即朝向要检查的物体（A）的物体光和参考光，用于通过旋转反射器（12）延迟参考光的光延迟机构（3），用于反射/返回来自光延迟机构（3）的参考光的固定镜（4），一半（2），用于将从被检查物体（A）返回的物体光与从光延迟机构返回的参考光组合;以及光检测器（11），用于检测包括外差干扰拍频信号的干涉光，半反射镜（2）。

2. 发明授权

US09498549B2 Sterilization method and sterilization processing apparatus 有权
标题翻译：灭菌方法和灭菌处理装置
公开(公告)号：US09498549B2
公开(公告)日：2016-11-22
申请号：US11992590
申请日：2007-08-24
申请人： Minoru Kanno , Masahiro Kohno , Atsuo Iwasawa , Takayuki Mokudai
发明人： Minoru Kanno , Masahiro Kohno , Atsuo Iwasawa , Takayuki Mokudai
IPC分类号： A61L2/03 , A61L2/16 , B08B3/08 , C02F1/467 , C02F1/461
CPC分类号： A61L2/035 , A61L2/16 , B08B3/08 , C02F1/4674 , C02F2001/46185
摘要： A sterilization method and sterilization processing apparatus having a high sterilization effect and capable of shortening a sterilization time are provided. An electrolysis apparatus 2 electrolyzes water in a reservoir 1 and generates strongly acidic electrolytic water in an anode chamber 11 and generates strongly alkaline electrolytic water in a cathode chamber 12. A first wash container 3 is provided with a drain having an on-off valve and retains the strongly alkaline electrolytic water in the cathode chamber 12. A second wash container 4 is hermetically sealable, provided with a drain having an on-off valve and retains the strongly acidic electrolytic water of the anode chamber 11. A gas jetting apparatus 5 has a collector pipe 51 communicating with the inside of the second wash container 4 and causes air or a chlorine gas collected from the inside of the second wash container 4 through the collector pipe 51 to jet in the strongly acidic electrolytic water inside the second wash container 4. A waste water container 6 receives waste water from a drain 31 of the first wash container 3 and a drain 41 of the second wash container 4.
摘要翻译：提供具有高灭菌效果并且能够缩短灭菌时间的灭菌方法和杀菌处理装置。电解装置2对储存器1中的水进行电解，并在阳极室11中产生强酸性电解水，并在阴极室12中产生强碱性电解水。第一洗涤容器3设置有具有开关阀的排水口，将强碱性电解水保持在阴极室12中。第二洗涤容器4是气密密封的，设置有具有开关阀的排水口并保持阳极室11的强酸性电解水。气体喷射装置5具有与第二洗涤容器4的内部连通并通过收集管51从第二洗涤容器4的内部收集的空气或氯气在第二洗涤容器4内的强酸性电解水中喷射的收集管51 废水容器6从第一洗涤容器3的排水管31和第二洗涤容器4的排水口41接收废水。

3. 发明授权

US5737251A Rank order filter 失效
公开(公告)号：US5737251A
公开(公告)日：1998-04-07
申请号：US851463
申请日：1997-05-05
申请人： Masahiro Kohno , Hiroshi Nittaya , Masahiro Kato
发明人： Masahiro Kohno , Hiroshi Nittaya , Masahiro Kato
IPC分类号： G06F7/22 , G06F17/18 , G06T5/20 , H03H17/02 , G06F7/00 , G05B1/00
CPC分类号： G06F9/30021 , G06F17/18 , G06F7/22 , H03H17/0263
摘要： A rank order filter is disclosed in which the maximum value, the minimum value and the median value are determined in a 3.times.3 local area having three sample values in each of column and row. The three sample values in the 3.times.3 local area are rearranged in descending order of magnitude by column, and the maximum values or the minimum values in each column are compared with each other thereby to determine the maximum value or the minimum value in the 3.times.3 local area. Also, after comparing the median values with each other in each column, the maximum value in the column having the minimum median value, the minimum value in the column having the maximum median value and the median value in the column having the median median value are compared with each other. The result of comparison is used to determine the median value in the 3.times.3 local area.

4. 发明授权

US5532948A Rank order filter 失效
标题翻译：排序顺序过滤器
公开(公告)号：US5532948A
公开(公告)日：1996-07-02
申请号：US177989
申请日：1994-01-06
申请人： Masahiro Kohno , Hiroshi Nittaya , Masahiro Kato
发明人： Masahiro Kohno , Hiroshi Nittaya , Masahiro Kato
IPC分类号： G06F7/22 , G06F17/18 , G06T5/20 , H03H17/02 , G06F7/00 , G06F7/02
CPC分类号： G06F9/30021 , G06F17/18 , G06F7/22 , H03H17/0263
摘要： A rank order filter is disclosed in which the maximum value, the minimum value and the median value are determined in a 3.times.3 local area having three sample values in each of column and row. The three sample values in the 3.times.3 local area are rearranged in descending order of magnitude by column, and the maximum values or the minimum values in each column are compared with each other thereby to determine the maximum value or the minimum value in the 3.times.3 local area. Also, after comparing the median values with each other in each column, the maximum value in the column having the minimum median value, the minimum value in the column having the maximum median value and the median value in the column having the median median value are compared with each other. The result of comparison is used to determine the median value in the 3.times.3 local area.
摘要翻译：公开了一种等级阶滤波器，其中在具有列和行的每一列中的三个采样值的3×3局部区域中确定最大值，最小值和中值。 3x3局部区域中的三个采样值按列逐个降序排列，并将每列中的最大值或最小值进行比较，从而确定3x3局部区域中的最大值或最小值。此外，在比较各列中的中值之后，具有最小中值，具有最大中值的列中的最小值和具有中值中值的列中的中值的列中的最大值为相互比较。比较结果用于确定3x3局部区域的中值。

5. 发明授权

US4856765A Spring apparatus 失效
标题翻译：弹簧装置
公开(公告)号：US4856765A
公开(公告)日：1989-08-15
申请号：US105599
申请日：1987-10-05
申请人： Masahiro Kohno , Akira Obata , Takayuki Kitamura , Kakuma Okazaki
发明人： Masahiro Kohno , Akira Obata , Takayuki Kitamura , Kakuma Okazaki
IPC分类号： B64G1/00 , A47C3/20 , B64G99/00 , B66F3/00 , F02K9/84 , F02K9/97 , F16F1/02 , F16F3/04 , F16M11/24
CPC分类号： B64G9/00 , A47C3/20 , B66F3/00 , F02K9/976 , F16F1/02 , F16M11/046 , F16M11/16 , F16M11/40 , F16M2200/065
摘要： A spring apparatus has a spring body including a plurality of elastic longitudinal beam members and a coupling beam member for holding the elastic longitudinal beam members at a predetermined interval. The apparatus further has a pair of spring retaining members for supporting the both ends of the spring body, and a rotary member rotatable provided around the central axis of the spring body as a center at least one one spring retaining member. At least one of the elastic longitudinal beam member is provided at one end of the rotary member. This spring apparatus is a tightly wound coil and made of the elastic longitudinal beam members in fully compressed state. When extended, each elastic longitudinal beam member is sequentially spirally deformed at larger pitch from the end. The twisting deformation of the elastic longitudinal beam member is released by rotation of the rotary member.
摘要翻译：弹簧装置具有包括多个弹性纵向梁构件的弹簧体和用于以预定间隔保持弹性纵向梁构件的联接梁构件。该装置还具有用于支撑弹簧体的两端的一对弹簧保持构件，以及以弹簧体的中心轴线为中心设置的至少一个弹簧保持构件的旋转构件。弹性纵向梁构件中的至少一个设置在旋转构件的一端。该弹簧装置是紧密缠绕的线圈，并由完全压缩状态的弹性纵向梁构件制成。当延伸时，每个弹性纵向梁构件从端部以较大的间距顺序地螺旋形变形。通过旋转构件的旋转来释放弹性纵向梁构件的扭转变形。

6. 发明授权

US4782168A 2,3-dihydro-2,3,5-trimethyl-4H-pyran-4-one derivative and sex attractant for drugstore beetles 失效
标题翻译： 2,3-二氢-2,3,5-三甲基-4H-吡喃-4-酮衍生物和用于药店甲虫的性引诱剂
公开(公告)号：US4782168A
公开(公告)日：1988-11-01
申请号：US844598
申请日：1986-03-27
申请人： Hisashi Kodama , Keiko Mochizuki , Masahiro Kohno , Akio Ohnishi , Mikio Ono
发明人： Hisashi Kodama , Keiko Mochizuki , Masahiro Kohno , Akio Ohnishi , Mikio Ono
IPC分类号： A01N43/16 , A01N49/00 , C07D309/32 , C07D309/30
CPC分类号： A01N49/00 , A01N43/16 , C07D309/32
摘要： A 2,3-dihydro-2,3,5-trimethyl-4H-pyran-4-one derivative represented by general formula: ##STR1## where R is ##STR2## --CH(OCH.sub.3).sub.2, --CH(OC.sub.2 H.sub.5).sub.2, --CHO, --CH.sub.2 OH, --CH.dbd.CH.sub.2, .dbd.CHCH.sub.2 CH.sub.3, --CH.dbd.CHCH.sub.3 or ##STR3## The derivative is useful as a sex attractant for drugstore beetles.
摘要翻译：其中R为-CH（OCH 3）2，-CH（OC 2 H 5）2）表示的2,3-二氢-2,3,5-三甲基-4H-吡喃-4-酮衍生物，其通式如下：，-CHO，-CH 2 OH，-CH = CH 2，= CHCH 2 CH 3，-CH = CHCH 3或该衍生物可用作药物甲虫的性引诱剂。

7. 发明授权

US4696905A Method for diagnosing cancer using ESR 失效
标题翻译：使用ESR诊断癌症的方法
公开(公告)号：US4696905A
公开(公告)日：1987-09-29
申请号：US608996
申请日：1984-05-10
申请人： Masaaki Aoyama , Mitsuharu Itabashi , Mariko Miura , Masahiro Kohno
发明人： Masaaki Aoyama , Mitsuharu Itabashi , Mariko Miura , Masahiro Kohno
IPC分类号： G01R33/60 , G01N24/00 , G01N33/48 , G01N33/50
CPC分类号： G01R33/60 , Y10T436/145555 , Y10T436/146666 , Y10T436/24
摘要： A method for diagnosis of cancer utilizing an ESR spectrometer comprised a first step for mixing cells from a patient with a solution of hematoporphyrin or hematoporphyrin derivative, a second step for isolating said cells from unreacted reagent and obtaining ESR spectral signal on said cells, a third step for finding quantity S.sub.x of the radicals contained in said cells on the basis of the ESR signal, and a fourth step for comparing value S.sub.x at a predetermined level.
摘要翻译：利用ESR光谱仪诊断癌症的方法包括将来自患者的细胞与血卟啉或血卟啉衍生物溶液混合的第一步骤，用于从所述细胞中分离所述细胞并获得ESR光谱信号的第二步骤，第三步基于ESR信号求出包含在所述单元格中的自由基的量Sx的步骤，以及用于比较预定水平的值Sx的第四步骤。

8. 发明授权

US4386054A Spin immunoassay apparatus 失效
标题翻译：自旋免疫测定仪
公开(公告)号：US4386054A
公开(公告)日：1983-05-31
申请号：US310745
申请日：1981-10-13
申请人： Makoto Takeuchi , Ekuo Yoshida , Masahiro Kohno
发明人： Makoto Takeuchi , Ekuo Yoshida , Masahiro Kohno
IPC分类号： G01N24/10 , G01N33/53 , G01N33/536 , G01N33/16
CPC分类号： G01N33/5302 , Y10S436/808 , Y10T436/24
摘要： A spin immunoassay apparatus includes means for sampling one of a plurality of sample solutions, a system for measuring certain amounts of the sample solution, a reaction system for mixing the sample solution with reagent which consists of antibody coupled with spin labelled antigen by antigen-antibody reaction and incubating the mixture for a certain period of time, and an electron spin resonance device for measuring the concentration of a spin labelled material extricated. The electron spin resonance device has a cavity resonator including a fixed cell. A flow system transfers the mixed sample solution and reagent into the cell. The intensity of a magnetic field applied to the cell is adjusted so that the maximum differential value or the minimum differential value of the ESR signal of the spin labelled material will be detected.
摘要翻译：自旋免疫测定装置包括用于对多个样品溶液中的一个进行取样的装置，用于测量某些量的样品溶液的系统，用于将样品溶液与由抗体 - 抗体与旋转标记抗原偶联的抗体组合的试剂混合的反应体系反应并将混合物温育一定时间，以及用于测量自旋标记物质浓度的电子自旋共振装置。电子自旋共振装置具有包括固定电池的空腔谐振器。流动系统将混合的样品溶液和试剂转移到细胞中。调整施加到单元的磁场的强度，使得将检测自旋标记材料的ESR信号的最大微分值或最小微分值。

9. 发明授权

US08729464B2 Method for determining stage of chronic kidney disease, device therefor and method for operating the same 有权
标题翻译：用于确定慢性肾脏疾病阶段的方法，其装置及其操作方法
公开(公告)号：US08729464B2
公开(公告)日：2014-05-20
申请号：US13700795
申请日：2011-05-30
申请人： Noriaki Tanaka , Masahiro Kohno , Emiko Sato , Kouichi Fujiwara
发明人： Noriaki Tanaka , Masahiro Kohno , Emiko Sato , Kouichi Fujiwara
IPC分类号： H01J49/04
CPC分类号： H01J49/0431 , A61B5/0059 , G01N30/34 , G01N30/7233 , G01N33/6893 , G01N2030/045 , G01N2030/8813 , G01N2800/347
摘要： This invention provides a method or device for determining the stage of chronic kidney disease.The present invention relates to a method for determining a stage of chronic kidney disease in a subject suffering from kidney disease, the method comprising the steps of: (A-1) measuring the content of at least one marker selected from the group consisting of markers (1) to (16) in a specimen from the subject, (B-1) determining the stage indicated by each marker by comparing the content of the at least one marker in the specimen from the subject, which has been measured in step (A-1), with a reference content range determined in each stage, and (C-1) determining that when each marker indicates the same stage, which has been determined in step (A-1), the chronic kidney disease in the subject is in that stage.
摘要翻译：本发明提供了一种用于确定慢性肾脏疾病阶段的方法或装置。本发明涉及一种用于确定患有肾脏疾病的受试者的慢性肾脏疾病阶段的方法，所述方法包括以下步骤：（A-1）测量选自标记物中的至少一种标志物的含量（B-1）通过比较在步骤（1）中测量的来自受试者的标本中的至少一个标记物的含量来确定每个标记物指示的阶段（B-1） A-1），每个阶段确定参考含量范围，和（C-1）确定当每个标记指示在步骤（A-1）中确定的相同阶段时，受试者中的慢性肾脏疾病在那个阶段

10. 发明授权

US06531320B1 Method of monitoring redox of blood plasma using ESR and method of estimating progress of dialysis 失效
标题翻译：使用ESR监测血浆氧化还原的方法和估算透析进展的方法
公开(公告)号：US06531320B1
公开(公告)日：2003-03-11
申请号：US09244239
申请日：1999-02-03
申请人： Masahiro Kohno , Shigeru Ohwada
发明人： Masahiro Kohno , Shigeru Ohwada
IPC分类号： G01N3349
CPC分类号： G01N1/38 , G01N1/44 , G01N33/491 , G01R33/60 , Y10T436/203332 , Y10T436/24 , Y10T436/25
摘要： A method of judging the redox (oxidation-reduction) in human blood plasma precisely in a short time using electron spin resonance (ESR) spectroscopy is provided. Also, a method of evaluating the functions of human kidneys, judging whether a dialysis is necessary, determining the dialysis time and judging the usefulness of dialysis materials is offered. First, a spin-trapping agent such as PBN is added to a human blood plasma, resulting in hydroxyl radicals in the plasma. The radicals are trapped and converted into a stable spin adduct (PBN-OH). The amount of the spin adduct is measured by an ESR spectrometer.
摘要翻译：提供了使用电子自旋共振（ESR）光谱法在短时间内精确地判断人血浆中的氧化还原（氧化还原）的方法。另外，提供了评价人肾功能的判断方法，是否需要透析，判断透析时间，判断透析材料的用途。首先，将诸如PBN的自旋捕获剂添加到人血浆中，导致血浆中的羟基自由基。将基团捕获并转化成稳定的旋转加合物（PBN-OH）。通过ESR光谱仪测量旋转加合物的量。

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