专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明授权

US08656908B2 Aerosol delivery systems and methods 有权
标题翻译：气溶胶输送系统和方法
公开(公告)号：US08656908B2
公开(公告)日：2014-02-25
申请号：US13099261
申请日：2011-05-02
申请人： Mark J. Papania , James J. Barry , Mark C. Bagley , Nabil A. Elkouh , Darin Knaus , Robert Trabka
发明人： Mark J. Papania , James J. Barry , Mark C. Bagley , Nabil A. Elkouh , Darin Knaus , Robert Trabka
IPC分类号： A61M11/00 , A61M15/00 , B05B17/06
CPC分类号： B05B17/0638 , A61M15/0033 , A61M15/0065 , A61M15/0085 , A61M2205/07 , A61M2205/3306 , A61M2205/825 , B05B12/008 , B05B12/082 , B05B17/0623 , B05B17/0676
摘要： Methods and systems for aerosol delivery of agents to a patient are described herein. The present system can be used to administer various types of agents, such as a vaccine or other types of pharmaceutical substances. Certain embodiments of the present system utilize an actuator coupled to a disposable aerosolizing element that aerosolizes an agent for delivery to a patient when acted upon by the actuator. The aerosolizing element prevents the agent from contacting the actuator and other non-disposable components of the system so that little or no cleaning or maintenance is required. The present system also can include an aerosolization rate monitor that monitors the rate at which an agent is being aerosolized and provides feedback to the user to ensure that the proper dose is being administered.
摘要翻译：本文描述了将药剂气雾剂递送至患者的方法和系统。本系统可用于施用各种类型的试剂，例如疫苗或其他类型的药物。本系统的某些实施例利用联接到一次性雾化元件的致动器，其在由致动器作用时使药剂雾化以递送给患者。雾化元件防止试剂与系统的致动器和其他非一次性部件接触，从而不需要或不需要清洁或维护。本系统还可以包括气雾化速率监测器，其监测试剂被雾化的速率，并向使用者提供反馈以确保施用适当的剂量。

2. 发明授权

US06230539B1 Ultra precision net forming process employing controlled plastic deformation of metals at elevated temperatures 失效
标题翻译：超精密网形成工艺采用高温金属控制塑性变形
公开(公告)号：US06230539B1
公开(公告)日：2001-05-15
申请号：US09389626
申请日：1999-09-03
申请人： Jerry M. Dickson , William R. Baschnagel , Mark C. Bagley
发明人： Jerry M. Dickson , William R. Baschnagel , Mark C. Bagley
IPC分类号： B21J106
CPC分类号： B21J9/20 , B21J3/00 , B21J5/02 , B21J13/02 , B21K1/025 , F42B14/06 , F42B14/061 , F42B14/068
摘要： An ultra precision net shape forming process is disclosed which can satisfy the requirements of MMW and sub-MMW components and sabots for small caliber armor piercing ammunition. The process is well suited to both moderate and high volume applications, and offers the potential for dramatically reducing piece part fabrication costs. The process involves closely controlled high temperature compression forming of metals with cycle times of the order of one minute or less, precise replication of all die features, and very low residual stresses. The ultra precision net shape forming cycle starts following insertion of the billet/blank into an open die. In the preheat phase the press is closed to preheat position where the billet/blank is enclosed in both halves of the die but no force is applied. Following preheat the part is formed employing displacement and force control to insure a fully formed part. After holding for a preset time at the peak force, the press is then commanded back to the loading position. The process has many of the attributes of conventional compression molding of plastics and is well suited to high volume, automated production of complex precision parts.
摘要翻译：公开了一种超精密网形成型工艺，可以满足MMW和次MMW组件的要求，并能满足小口径穿甲弹药的要求。该工艺非常适合中等和高容量应用，并且具有显着降低零件制造成本的潜力。该方法包括精密控制的高温压缩成形金属，循环时间为1分钟或更短，精确复制所有模具特征，以及非常低的残余应力。在将坯料/坯料插入开模中之后开始超精密网状成形循环。在预热阶段，压机关闭到预热位置，其中坯料/坯料被封闭在模具的两半中，但不施加力。在预热之后，使用位移和力控制形成部件，以确保完全成形的部件。在峰值力保持预设时间后，再按下按钮返回装载位置。该方法具有传统的塑料压缩成型的许多属性，并且非常适合于大量自动化生产复杂的精密零件。

3. 发明授权

US09492068B2 Nasal aerosol delivery system 有权
标题翻译：鼻气雾剂输送系统
公开(公告)号：US09492068B2
公开(公告)日：2016-11-15
申请号：US13701992
申请日：2011-06-03
申请人： Mark J. Papania , James J. Barry , Mark C. Bagley , Eric M. Friets , Darin A. Knaus
发明人： Mark J. Papania , James J. Barry , Mark C. Bagley , Eric M. Friets , Darin A. Knaus
IPC分类号： A61M15/08 , A61B1/233 , A61M11/00 , A61B1/04 , A61B1/06 , A61M15/00 , A61M16/04 , A61M16/00
CPC分类号： A61B1/233 , A61B1/00045 , A61B1/04 , A61B1/06 , A61M11/00 , A61M11/005 , A61M11/006 , A61M11/007 , A61M15/0098 , A61M15/08 , A61M16/0488 , A61M16/107 , A61M31/00 , A61M2016/0024 , A61M2016/0042 , A61M2205/3365 , A61M2205/3375 , A61M2205/43 , A61M2205/502 , A61M2205/581 , A61M2205/6036 , A61M2205/6054 , A61M2205/6063
摘要： A nasal delivery device can include a nasal prong and an activation member. The nasal prong can comprises an opening at a top and bottom portion of the prong to allow for the passage of an aerosolized treatment agent through the nasal prong. The activation member can be positioned on the nasal delivery device at a location that is spaced apart from the subject's oral cavity when the nasal prong is received into the nostril of the subject. The activation member can be configured to detect a desired exhalation state of the subject and upon detection of the desired exhalation state, the activation member activates the delivery of the aerosolized treatment agent.
摘要翻译：鼻输送装置可以包括鼻针和激活构件。鼻插管可以包括在插脚的顶部和底部的开口，以允许雾化处理剂通过鼻插管。当鼻塞被插入到受试者的鼻孔中时，激活构件可以在与受试者的口腔间隔开的位置处定位在鼻输送装置上。激活构件可以被配置为检测对象的期望呼气状态，并且在检测到所需的呼气状态时，激活构件激活雾化处理剂的输送。

4. 发明申请

US20120118283A1 Systems and methods for aerosol delivery of agents 有权
标题翻译：用于药剂气溶胶输送的系统和方法
公开(公告)号：US20120118283A1
公开(公告)日：2012-05-17
申请号：US11796313
申请日：2007-04-27
申请人： Mark James Papania , James J. Barry , Nabil A. Elkouh , Mark C. Bagley
发明人： Mark James Papania , James J. Barry , Nabil A. Elkouh , Mark C. Bagley
IPC分类号： A61M11/02
CPC分类号： A61M11/005 , A61M11/001 , A61M11/06 , A61M15/0033 , A61M15/0066 , A61M15/0085 , A61M15/08 , A61M16/0057 , A61M16/0666 , A61M16/107 , A61M16/14 , A61M2205/07 , A61M2205/071 , A61M2205/3606 , A61M2205/8206 , A61M2205/8225 , A61M2205/825
摘要： Aerosol delivery systems and methods for delivering an agent to a patient are described herein. The present invention includes embodiments comprising an insulated receptacle connected to a body to hold a vial of an agent to be delivered to a patient. The vial is located in an inverted position within the receptacle and connected to the housing. One or more reusable thermal packs can be located on the inner sides of the receptacle, to maintain a selected temperature surrounding the vial. The agent is administered to a patient by placing a prong into one of the patient's orifices and then activating an aerosol delivery system. Such systems comprise jet aerosolization and pneumatic and ultrasonic nebulizers and preferably are portable.
摘要翻译：本文描述了用于将药剂递送至患者的气溶胶递送系统和方法。本发明包括实施例，该实施例包括连接到身体的绝缘插座，用于保持要递送给患者的药剂瓶。小瓶位于插座内的倒置位置并连接到外壳。一个或多个可重复使用的热包装可以位于容器的内侧，以保持围绕小瓶的选定温度。通过将一个插入物插入患者的一个孔中，然后激活气雾剂输送系统，向患者施用该药剂。这样的系统包括喷雾雾化和气动和超声雾化器，并且优选是便携式的。

5. 发明授权

US07954486B2 Aerosol delivery systems and methods 有权
标题翻译：气溶胶输送系统和方法
公开(公告)号：US07954486B2
公开(公告)日：2011-06-07
申请号：US10587814
申请日：2005-04-01
申请人： Mark J. Papania , James J. Barry , Mark C. Bagley , Nabil A. Elkouh , Darin Knaus , Robert Trabka
发明人： Mark J. Papania , James J. Barry , Mark C. Bagley , Nabil A. Elkouh , Darin Knaus , Robert Trabka
IPC分类号： A61M11/00 , A61M15/00 , B05B17/06
CPC分类号： B05B17/0638 , A61M15/0033 , A61M15/0065 , A61M15/0085 , A61M2205/07 , A61M2205/3306 , A61M2205/825 , B05B12/008 , B05B12/082 , B05B17/0623 , B05B17/0676
摘要： Methods and systems for aerosol delivery of agents to a patient are described herein. The present system can be used to administer various types of agents, such as a vaccine or other types of pharmaceutical substances. Certain embodiments of the present system utilize an actuator coupled to a disposable aerosolizing element that aerosolizes an agent for delivery to a patient when acted upon by the actuator. The aerosolizing element prevents the agent from contacting the actuator and other non-disposable components of the system so that little or no cleaning or maintenance is required. The present system also can include an aerosolization rate monitor that monitors the rate at which an agent is being aerosolized and provides feedback to the user to ensure that the proper dose is being administered.
摘要翻译：本文描述了将药剂气雾剂递送至患者的方法和系统。本系统可用于施用各种类型的试剂，例如疫苗或其他类型的药物。本系统的某些实施例利用联接到一次性雾化元件的致动器，其在由致动器作用时使药剂雾化以递送给患者。雾化元件防止试剂与系统的致动器和其他非一次性部件接触，从而不需要或不需要清洁或维护。本系统还可以包括气雾化速率监测器，其监测试剂被雾化的速率，并向使用者提供反馈以确保施用适当的剂量。

6. 发明申请

US20130072755A1 NASAL AEROSOL DELIVERY SYSTEM 有权
标题翻译： NASAL AEROSOL交付系统
公开(公告)号：US20130072755A1
公开(公告)日：2013-03-21
申请号：US13701992
申请日：2011-06-03
申请人： Mark J. Papania , James J. Barry , Mark C. Bagley , Eric M. Friets , Darin A. Knaus
发明人： Mark J. Papania , James J. Barry , Mark C. Bagley , Eric M. Friets , Darin A. Knaus
IPC分类号： A61B1/233 , A61B1/06 , A61B1/04 , A61M11/00
CPC分类号： A61B1/233 , A61B1/00045 , A61B1/04 , A61B1/06 , A61M11/00 , A61M11/005 , A61M11/006 , A61M11/007 , A61M15/0098 , A61M15/08 , A61M16/0488 , A61M16/107 , A61M31/00 , A61M2016/0024 , A61M2016/0042 , A61M2205/3365 , A61M2205/3375 , A61M2205/43 , A61M2205/502 , A61M2205/581 , A61M2205/6036 , A61M2205/6054 , A61M2205/6063
摘要： A nasal delivery device can include a nasal prong and an activation member. The nasal prong can comprises an opening at a top and bottom portion of the prong to allow for the passage of an aerosolized treatment agent through the nasal prong. The activation member can be positioned on the nasal delivery device at a location that is spaced apart from the subject's oral cavity when the nasal prong is received into the nostril of the subject. The activation member can be configured to detect a desired exhalation state of the subject and upon detection of the desired exhalation state, the activation member activates the delivery of the aerosolized treatment agent.
摘要翻译：鼻输送装置可以包括鼻针和激活构件。鼻插管可以包括在插脚的顶部和底部的开口，以允许雾化处理剂通过鼻插管。当鼻塞被插入到受试者的鼻孔中时，激活构件可以在与受试者的口腔间隔开的位置处定位在鼻输送装置上。激活构件可以被配置为检测对象的期望呼气状态，并且在检测到所需的呼气状态时，激活构件激活雾化处理剂的输送。

7. 发明授权

US07699804B2 Fluid ejection system 失效
标题翻译：流体喷射系统
公开(公告)号：US07699804B2
公开(公告)日：2010-04-20
申请号：US10768854
申请日：2004-01-30
申请人： James J. Barry , Mark C. Bagley , Peter L. Burghardt , Steven J. Fulton
发明人： James J. Barry , Mark C. Bagley , Peter L. Burghardt , Steven J. Fulton
IPC分类号： A61M37/00
CPC分类号： A61M5/30 , A61M5/204 , A61M5/286 , A61M5/31596 , A61M2005/312 , A61M2005/3128 , A61M2005/31598
摘要： A fluid ejection system (20) comprising a cartridge (24), an ejector (32, 300) and, optionally, a fill station (28) for filling the cartridge with a fluid, such as a vaccine. In some embodiments (52), the cartridge includes a transfer passageway (96) for receiving fluid from the fill station. In other embodiments (200, 400), the cartridge includes a vented fluid reservoir (208, 408) offset from an ejection chamber (224, 420). In yet other embodiments (500, 600), the cartridge includes a vented fluid reservoir chamber (512, 636) inline with the ejection chamber (508, 644). In still other embodiments (700, 1000, 1100), the cartridge includes first and second chambers (728, 736, 1036, 1048, 1136, 1148) initially fluidly sealed from on another by a valve, e.g., either a traveling valve (704, 800, 900, 1200, 1300) or a temporarily stationary valve (1004, 1104).
摘要翻译：流体喷射系统（20），其包括筒（24），喷射器（32,300）和可选地用于用诸如疫苗的流体填充盒的填充站（28）。在一些实施例（52）中，盒包括用于从填充站接收流体的传送通道（96）。在其他实施例（200,400）中，该盒包括从喷射室（224,420）偏移的排出的流体储存器（208,408）。在其它实施例（500,600）中，该盒包括与喷射室（508,644）成直线的通气的流体储存室（512,636）。在另外的其它实施例（700,1000,1100）中，盒包括首先和第二腔室（728,736,1036,1048,1136,1148），其通过阀例如流动阀（704），800,900,1200,1300）或临时固定的阀（1004,1104）。

8. 发明申请

US20090223513A1 Aerosol delivery systems and methods 有权
标题翻译：气溶胶输送系统和方法
公开(公告)号：US20090223513A1
公开(公告)日：2009-09-10
申请号：US10587814
申请日：2005-04-01
申请人： Mark J Papania , James J. Barry , Mark C. Bagley , Nabil A. Elkouh , Darin Knaus , Robert Trabka
发明人： Mark J Papania , James J. Barry , Mark C. Bagley , Nabil A. Elkouh , Darin Knaus , Robert Trabka
IPC分类号： A61M11/02 , A61M11/00
CPC分类号： B05B17/0638 , A61M15/0033 , A61M15/0065 , A61M15/0085 , A61M2205/07 , A61M2205/3306 , A61M2205/825 , B05B12/008 , B05B12/082 , B05B17/0623 , B05B17/0676
摘要： Methods and systems for aerosol delivery of agents to a patient are described herein. The present system can be used to administer various types of agents, such as a vaccine or other types of pharmaceutical substances. Certain embodiments of the present system utilize an actuator coupled to a disposable aerosolizing element that aerosolizes an agent for delivery to a patient when acted upon by the actuator. The aerosolizing element prevents the agent from contacting the actuator and other non-disposable components of the system so that little or no cleaning or maintenance is required. The present system also can include an aerosolization rate monitor that monitors the rate at which an agent is being aerosolized and provides feedback to the user to ensure that the proper dose is being administered.
摘要翻译：本文描述了将药剂气雾剂递送至患者的方法和系统。本系统可用于施用各种类型的试剂，例如疫苗或其他类型的药物。本系统的某些实施例利用联接到一次性雾化元件的致动器，其在由致动器作用时使药剂雾化以递送给患者。雾化元件防止试剂与系统的致动器和其他非一次性部件接触，从而不需要或不需要清洁或维护。本系统还可以包括气雾化速率监测器，其监测试剂被雾化的速率，并向使用者提供反馈以确保施用适当的剂量。

9. 发明授权

US07225807B2 Systems and methods for aerosol delivery of agents 有权
标题翻译：用于药剂气溶胶输送的系统和方法
公开(公告)号：US07225807B2
公开(公告)日：2007-06-05
申请号：US10471620
申请日：2002-03-13
申请人： Mark James Papania , James J. Barry , Nabil A. Elkouh , Mark C. Bagley
发明人： Mark James Papania , James J. Barry , Nabil A. Elkouh , Mark C. Bagley
IPC分类号： A61M15/00 , A61M16/10 , A61M16/00 , A61M15/08 , A61M11/00 , F16K11/00 , G05D11/02
CPC分类号： A61M11/005 , A61M11/001 , A61M11/06 , A61M15/0033 , A61M15/0066 , A61M15/0085 , A61M15/08 , A61M16/0057 , A61M16/0666 , A61M16/107 , A61M16/14 , A61M2205/07 , A61M2205/071 , A61M2205/3606 , A61M2205/8206 , A61M2205/8225 , A61M2205/825
摘要： Aerosol delivery systems and methods for delivering an agent to a patient are described herein. The present invention includes embodiments comprising an insulated receptacle connected to a body to hold a vial of an agent to be delivered to a patient. The vial is located in an inverted position within the receptacle and connected to the housing. One or more reusable thermal packs can be located on the inner sides of the receptacle, to maintain a selected temperature surrounding the vial. The agent is administered to a patient by placing a prong into one of the patient's orifices and then activating an aerosol delivery system. Such systems comprise jet aerosolization and pneumatic and ultrasonic nebulizers and preferably are portable.
摘要翻译：本文描述了用于将药剂递送至患者的气溶胶递送系统和方法。本发明包括实施例，该实施例包括连接到身体的绝缘插座，用于保持要递送给患者的药剂瓶。小瓶位于插座内的倒置位置并连接到外壳。一个或多个可重复使用的热包装可以位于容器的内侧，以保持围绕小瓶的选定温度。通过将一个插入物插入患者的一个孔中，然后激活气雾剂输送系统，向患者施用该药剂。这种系统包括喷雾雾化和气动和超声雾化器，并且优选是便携式的。

10. 发明申请

US20110203580A1 AEROSOL DELIVERY SYSTEMS AND METHODS 有权
标题翻译：航空运输系统和方法
公开(公告)号：US20110203580A1
公开(公告)日：2011-08-25
申请号：US13099261
申请日：2011-05-02
申请人： Mark J. Papania , James J. Barry , Mark C. Bagley , Nabil A. Elkouh , Darin Knaus , Robert Trabka
发明人： Mark J. Papania , James J. Barry , Mark C. Bagley , Nabil A. Elkouh , Darin Knaus , Robert Trabka
IPC分类号： A61M11/00
CPC分类号： B05B17/0638 , A61M15/0033 , A61M15/0065 , A61M15/0085 , A61M2205/07 , A61M2205/3306 , A61M2205/825 , B05B12/008 , B05B12/082 , B05B17/0623 , B05B17/0676
摘要： Methods and systems for aerosol delivery of agents to a patient are described herein. The present system can be used to administer various types of agents, such as a vaccine or other types of pharmaceutical substances. Certain embodiments of the present system utilize an actuator coupled to a disposable aerosolizing element that aerosolizes an agent for delivery to a patient when acted upon by the actuator. The aerosolizing element prevents the agent from contacting the actuator and other non-disposable components of the system so that little or no cleaning or maintenance is required. The present system also can include an aerosolization rate monitor that monitors the rate at which an agent is being aerosolized and provides feedback to the user to ensure that the proper dose is being administered.
摘要翻译：本文描述了将药剂气雾剂递送至患者的方法和系统。本系统可用于施用各种类型的试剂，例如疫苗或其他类型的药物。本系统的某些实施例利用联接到一次性雾化元件的致动器，其在由致动器作用时使药剂雾化以递送给患者。雾化元件防止试剂与系统的致动器和其他非一次性部件接触，从而不需要或不需要清洁或维护。本系统还可以包括气雾化速率监测器，其监测试剂被雾化的速率，并向使用者提供反馈以确保施用适当的剂量。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式