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1. 发明授权

US5441667A Detergent composition 失效
标题翻译：水性非乳化皮肤清洁组合物的聚醚改性硅酮
公开(公告)号：US5441667A
公开(公告)日：1995-08-15
申请号：US229100
申请日：1994-04-18
申请人： Manabu Tonomura , Yasushi Kajihara
发明人： Manabu Tonomura , Yasushi Kajihara
IPC分类号： A61K8/58 , A61K8/894 , A61K8/898 , A61Q1/14 , A61Q19/10 , C11D3/37 , C11D3/02
CPC分类号： C11D3/3738 , A61K8/585 , A61K8/894 , A61Q1/14 , A61Q19/10 , C11D3/373 , Y10S514/846
摘要： A detergent composition comprising a polyether-modified silicone having a molecular weight of 3,500 or smaller as a detergent component is disclosed. The detergent composition can effectively eliminate oily residue such as the residues from makeup, e.g. lipsticks, foundations, etc., sebum, and the like in a short period of time, while imparting a pleasant sensation to the skin during and after cleansing.
摘要翻译：公开了一种洗涤剂组合物，其包含分子量为3,500以下的聚醚改性的硅氧烷作为洗涤剂成分。洗涤剂组合物可以有效地消除油性残留物，例如化妆品残留物，例如，口红，基础等，皮脂等，同时在清洁期间和之后赋予皮肤愉悦的感觉。

2. 发明授权

US5049375A Oral compositions containing colloidal fluoride 失效
标题翻译：含有胶态氟化物的口服组合物
公开(公告)号：US5049375A
公开(公告)日：1991-09-17
申请号：US527776
申请日：1990-05-24
申请人： Satoshi Tsujita , Manabu Tonomura , Shigeto Kayane , Takashi Imamura
发明人： Satoshi Tsujita , Manabu Tonomura , Shigeto Kayane , Takashi Imamura
IPC分类号： A61K8/21 , A61K33/16 , A61Q11/00
CPC分类号： A61Q11/00 , A61K8/21 , B82Y5/00 , A61K2800/413
摘要： A colloidal solution comprises a fluoride(s) being difficultiy soluble in water comprises colloidal particles of the fluoride having a particle size of 0.005 to 1 micron, said fluoride having a fluoride ion concentration of 1 to 10,000 ppm in the state of saturation.

3. 发明授权

US5693258A Method for improving foaming properties and foaming composition 失效
标题翻译：改善发泡性能和发泡组合物的方法
公开(公告)号：US5693258A
公开(公告)日：1997-12-02
申请号：US219937
申请日：1994-03-30
申请人： Manabu Tonomura , Tsuyoshi Ohtomo
发明人： Manabu Tonomura , Tsuyoshi Ohtomo
IPC分类号： A61K8/30 , A61K8/00 , A61K8/02 , A61K8/11 , A61K8/37 , A61K9/46 , A61Q5/02 , A61Q11/00 , A61Q19/10 , B01F17/34 , B01F17/42 , B01J13/00
CPC分类号： A61K8/90 , A61K8/375 , A61K8/86 , A61Q19/10 , A61K2800/596 , A61K2800/75 , Y10S516/01 , Y10S516/918 , Y10S516/92
摘要： A method for improving the foaming property of a nonionic surfactant having a straight-chain alkyl group containing from 10 to 16 carbon atoms, and an HLB value of about 13.5 or more is disclosed, which comprises adding (b) a fatty acid monoglyceride represented by formula (I): R.sup.1 --CO--OCH.sub.2 CH(OH)CH.sub.2 OH (I) wherein R.sup.1 represents a straight-chain alkyl group having from 9 to 15 carbon atoms, to (a) the nonionic surfactant in a (b)/(a) weight ratio of from 2/8 to 6/5. A low-irritating foaming composition is also disclosed, which comprises (a) a nonionic surfactant having a straight-chain alkyl group containing from 10 to 16 carbon atoms as a hydrophobic group, and an HLB value of about 13.5 or more and (b) a fatty acid monoglyceride represented by formula (I): R.sup.1 --CO--OCH.sub.2 CH(OH)CH.sub.2 OH (I) wherein R.sup.1 represents a straight chain alkyl group having from 9 to 15 carbon atoms, in a (b)/(a) weight ratio of from 2/8 to 6/5.
摘要翻译：公开了一种提高含有10〜16个碳原子的直链烷基，HLB值约为13.5以上的非离子性表面活性剂的发泡性的方法，该方法包括：（b）以（b）表示的脂肪酸单甘油酯式（I）：其中R 1表示具有9至15个碳原子的直链烷基的R1-CO-OCH2CH（OH）CH2OH（Ⅰ），（a）（b）/（a）中的非离子表面活性剂，重量比为2/8至6/5。还公开了一种低刺激性发泡组合物，其包含（a）具有含有10至16个碳原子的直链烷基作为疏水基团，HLB值为约13.5或更高的非离子表面活性剂和（b）由式（I）表示的脂肪酸单甘油酯：（b）/（a）重量比的R 1 -CO-OCH 2 CH（OH）CH 2 OH（I）其中R 1表示具有9至15个碳原子的直链烷基为2/8至6/5。

4. 发明授权

US08673271B2 Compositions for mouth containing an anionic surfactant having reduced astringency 有权
标题翻译：含有减少涩味的阴离子表面活性剂的口服组合物
公开(公告)号：US08673271B2
公开(公告)日：2014-03-18
申请号：US10497849
申请日：2002-12-20
申请人： Kazuhiko Kato , Manabu Tonomura
发明人： Kazuhiko Kato , Manabu Tonomura
IPC分类号： A61Q11/00 , A61K8/02
CPC分类号： A61Q11/00 , A61K8/19 , A61K8/24 , A61K8/362 , A61K8/365 , A61K8/375 , A61K8/39 , A61K8/4973 , A61K8/86 , A61K8/90
摘要： The present invention relates to an oral care composition, which contains the following components (A), (B) and (C): (A) an inorganic acid and/or an organic acid, (B) an anionic surfactant, (C) at least one compound selected from polyglycerin fatty acid esters, sorbitan fatty acid esters, polyoxyethylene higher alcohol ethers having from 6 to 14 carbon atoms, polyoxyethylene fatty acid esters and polyoxyethylene polyoxypropylene copolymers. The oral care composition according to the present invention is significantly excellent in reducing astringency and bitterness inherent in anionic surfactants.
摘要翻译：本发明涉及含有以下组分（A），（B）和（C）的口腔护理组合物：（A）无机酸和/或有机酸，（B）阴离子表面活性剂，（C）至少一种选自聚甘油脂肪酸酯，脱水山梨糖醇脂肪酸酯，具有6至14个碳原子的聚氧乙烯高级醇醚，聚氧乙烯脂肪酸酯和聚氧乙烯聚氧丙烯共聚物的化合物。根据本发明的口腔护理组合物在减少阴离子表面活性剂固有的涩味和苦味方面显着优异。

5. 发明申请

US20050042183A1 Compositions for mouth 有权
标题翻译：嘴的组成
公开(公告)号：US20050042183A1
公开(公告)日：2005-02-24
申请号：US10497849
申请日：2002-12-20
申请人： Kazuhiko Kato , Manabu Tonomura
发明人： Kazuhiko Kato , Manabu Tonomura
IPC分类号： A61K8/19 , A61K8/24 , A61K8/362 , A61K8/365 , A61K8/37 , A61K8/39 , A61K8/49 , A61K8/86 , A61K8/90 , A61Q11/00 , A61K7/16
CPC分类号： A61Q11/00 , A61K8/19 , A61K8/24 , A61K8/362 , A61K8/365 , A61K8/375 , A61K8/39 , A61K8/4973 , A61K8/86 , A61K8/90
摘要： The present invention relates to an oral care composition, which contains the following components (A), (B) and (C): (A) an inorganic acid and/or an organic acid, (B) an anionic surfactant, (C) at least one compound selected from polyglycerin fatty acid esters, sorbitan fatty acid esters, polyoxyethylene higher alcohol ethers having from 6 to 14 carbon atoms, polyoxyethylene fatty acid esters and polyoxyethylene polyoxypropylene copolymers. The oral care composition according to the present invention is significantly excellent in reducing astringency and bitterness inherent in anionic surfactants.
摘要翻译：本发明涉及含有以下组分（A），（B）和（C）的口腔护理组合物：（A）无机酸和/或有机酸，（B）阴离子表面活性剂，（C）至少一种选自聚甘油脂肪酸酯，脱水山梨糖醇脂肪酸酯，具有6至14个碳原子的聚氧乙烯高级醇醚，聚氧乙烯脂肪酸酯和聚氧乙烯聚氧丙烯共聚物的化合物。根据本发明的口腔护理组合物在减少阴离子表面活性剂固有的涩味和苦味方面显着优异。

6. 发明授权

US5554315A Foaming surfactant composition comprising fatty acid polyoxyalkylene lower alkyl ether and fatty acid monoglyceride 失效
标题翻译：发泡表面活性剂组合物，其包含脂肪酸聚氧化烯低级烷基醚和脂肪酸单甘油酯
公开(公告)号：US5554315A
公开(公告)日：1996-09-10
申请号：US364687
申请日：1994-12-28
申请人： Manabu Tonomura , Masaaki Iwahashi , Toyomi Koike
发明人： Manabu Tonomura , Masaaki Iwahashi , Toyomi Koike
IPC分类号： A61K8/00 , A61K8/11 , A61K8/37 , A61K8/39 , A61Q5/02 , A61Q11/00 , A61Q19/10 , B01F17/44 , C11D1/66 , C11D1/72 , C11D1/74 , C11D1/825 , C11D10/04 , C11D11/00
CPC分类号： C11D3/0094 , A61K8/375 , A61K8/86 , A61Q19/10 , C11D1/825 , A61Q5/02 , C11D1/721 , C11D1/74 , Y10S516/06
摘要： A surfactant composition containing a fatty acid polyoxyalkylene lower alkyl ether represented by formula (1):R(OR.sup.1).sub.n OR.sup.2 (1)wherein R represents an alkanoyl or alkenoyl group having from 10 to 18 carbon atoms;R.sup.1 represents an alkylene having from 2 to 4 carbon atoms;R.sup.2 represents a lower alkyl group; andn is from 5 to 100 on the average; and a fatty acid monoglyceride represented by formula (2):R.sup.3 OCH.sub.2 CH(OH)CH.sub.2 OH (2)wherein R.sup.3 represents an alkanoyl group having from 8 to 16 carbon atoms or an alkenoyl group having from 12 to 22 carbon atoms;are disclosed.The foaming properties of a fatty acid polyoxyalkylene lower alkyl ether of formula (1) are improved by adding a fatty acid monoglyceride represented by formula (2) to the fatty acid polyoxyalkylene lower alkyl ether of formula (1).
摘要翻译：含有式（1）表示的脂肪酸聚氧化烯低级烷基醚的表面活性剂组合物：R（OR1）nOR2（1）其中R表示碳原子数为10〜18的烷酰基或烯酰基; R1表示具有2至4个碳原子的亚烷基; R2表示低级烷基; n平均为5〜100; 和由式（2）表示的脂肪酸单甘油酯：R3OCH2CH（OH）CH2OH（2）其中R3表示碳原子数为8〜16的烷酰基或碳原子数为12〜22的链烯酰基; 被披露。通过向式（1）的脂肪酸聚氧化烯低级烷基醚加入由式（2）表示的脂肪酸单甘油酯来改善式（1）的脂肪酸聚氧化烯低级烷基醚的发泡性能。

7. 发明授权

US5130146A Fluoride colloid and oral composition 失效
标题翻译：氟化物胶体和口服组合物
公开(公告)号：US5130146A
公开(公告)日：1992-07-14
申请号：US712742
申请日：1991-06-10
申请人： Satoshi Tsujita , Manabu Tonomura , Shigeto Kayane , Takashi Imamura
发明人： Satoshi Tsujita , Manabu Tonomura , Shigeto Kayane , Takashi Imamura
IPC分类号： A61K8/21 , A61K33/16 , A61Q11/00
CPC分类号： A61Q11/00 , A61K8/21 , B82Y5/00 , A61K2800/413
摘要： A colloidal solution comprises a fluoride(s) being difficultly soluble in water comprises colloidal particles of the fluoride having a particle size of 0.005 to 1 micron, said fluoride having a fluoride ion concentration of 1 to 10,000 ppm in the state of saturation.

8. 发明授权

US08206689B2 Oral preparation and chewing gum 有权
标题翻译：口服制剂和口香糖
公开(公告)号：US08206689B2
公开(公告)日：2012-06-26
申请号：US10533080
申请日：2003-10-31
申请人： Kazuhiko Kato , Yoshinori Murakami , Yoshiyuki Muroi , Manabu Tonomura , Mitsuyoshi Kashiwagi
发明人： Kazuhiko Kato , Yoshinori Murakami , Yoshiyuki Muroi , Manabu Tonomura , Mitsuyoshi Kashiwagi
IPC分类号： A61K8/00 , A61K8/21
CPC分类号： A61K8/365 , A61K8/19 , A61K8/21 , A61Q11/00
摘要： The invention provides an oral preparation or a chewing gum comprising an organic acid and/or inorganic acid and a fluoride ion supplying compound, wherein a light scattering layer is formed inside enamel of the teeth when the oral preparation or the chewing gum is applied to teeth. An internal tooth colored layer in the enamel is masked by the light scattering layer, and a white appearance is imparted to the teeth.
摘要翻译：本发明提供一种包含有机酸和/或无机酸和氟化物离子供给化合物的口腔制剂或口香糖，其中当将口腔制剂或口香糖施用于牙齿时，在牙釉质内形成光散射层。牙釉质中的内牙色层被光散射层掩蔽，并且赋予牙齿白色外观。

9. 发明申请

US20060099153A1 Oral preparation and chewing gum 有权
标题翻译：口服制剂和口香糖
公开(公告)号：US20060099153A1
公开(公告)日：2006-05-11
申请号：US10533080
申请日：2003-10-31
申请人： Kazuhiko Kato , Yoshinori Murakami , Yoshiyuki Muroi , Manabu Tonomura , Mitsuyoshi Kashiwagi
发明人： Kazuhiko Kato , Yoshinori Murakami , Yoshiyuki Muroi , Manabu Tonomura , Mitsuyoshi Kashiwagi
IPC分类号： A61K8/21
CPC分类号： A61K8/365 , A61K8/19 , A61K8/21 , A61Q11/00
摘要： The invention provides an oral preparation or a chewing gum comprising an organic acid and/or inorganic acid and a fluoride ion supplying compound, wherein a light scattering layer is formed inside enamel of the teeth when the oral preparation or the chewing gum is applied to teeth. An internal tooth colored layer in the enamel is masked by the light scattering layer, and a white appearance is imparted to the teeth.
摘要翻译：本发明提供一种包含有机酸和/或无机酸和氟化物离子供给化合物的口腔制剂或口香糖，其中当将口腔制剂或口香糖施用于牙齿时，在牙釉质内形成光散射层。牙釉质中的内牙色层被光散射层掩蔽，并且赋予牙齿白色外观。

10. 发明授权

US5972860A Framed soap composition containing non-ionic surfactant and inorganic salt 失效
标题翻译：含有非离子表面活性剂和无机盐的含皂组合物
公开(公告)号：US5972860A
公开(公告)日：1999-10-26
申请号：US988380
申请日：1997-12-10
申请人： Yoshiyuki Eshita , Manabu Tonomura , Toshio Nozaki , Hironobu Otani , Takeshi Hasegawa
发明人： Yoshiyuki Eshita , Manabu Tonomura , Toshio Nozaki , Hironobu Otani , Takeshi Hasegawa
IPC分类号： C11D1/04 , C11D1/12 , C11D1/29 , C11D1/72 , C11D1/74 , C11D3/02 , C11D10/04 , C11D13/00 , C11D13/16 , C11D17/00 , C11D17/02 , A61K7/50
CPC分类号： C11D3/046 , C11D10/04 , C11D10/045 , C11D17/006 , C11D17/02 , C11D1/04 , C11D1/126 , C11D1/29 , C11D1/72 , C11D1/74
摘要： A framed soap composition comprises (a) from 20 to 50% by weight of a fatty acid soap, (b) from 1 to 15% by weight of a nonionic surfactant, and (c) from 0.1 to 5% by weight of an inorganic salt. A framed soap composition incorporated with air bubbles is produced by melting a mixture containing these components while heating the mixture in the presence of water, subjecting the resultant molten material to aeration treatment to incorporate air bubbles, and pouring the resultant molten material incorporated with air bubbles, into a frame followed by cooling to harden the molten material.
摘要翻译：框架皂组合物包含（a）20至50重量％的脂肪酸皂，（b）1至15重量％的非离子表面活性剂，和（c）0.1至5重量％的无机盐。通过在含水的情况下加热混合物来熔化含有这些组分的混合物，使所得到的熔融材料进行通气处理以引入气泡，并将所得的熔融材料注入气泡中，，进入框架，然后冷却以使熔融材料硬化。

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