专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2011008581A3 DEVICES, METHODS, AND KITS FOR DETERMINING ANALYTE CONCENTRATIONS 审中-公开
标题翻译：用于确定分析物浓度的装置，方法和试剂盒
公开(公告)号：WO2011008581A3
公开(公告)日：2011-04-21
申请号：PCT/US2010040845
申请日：2010-07-01
申请人： FREELANCE CORP , FINKELSHTEIN IRINA V , MOYER JAMES W , POTTS RUSSEL O , SAGE BURTON H , SHARTLE ROBERT J , WILSON DONALD R , WONG BRUCE D
发明人： FINKELSHTEIN IRINA V , MOYER JAMES W , POTTS RUSSEL O , SAGE BURTON H , SHARTLE ROBERT J , WILSON DONALD R , WONG BRUCE D
IPC分类号： G01N33/48 , G01N21/25 , G01N21/78 , G01N33/487 , G01N33/52
CPC分类号： C12Q1/006 , A61B5/14517 , A61B5/14532 , A61B5/1455 , A61B10/0064 , G01N21/78 , G01N21/8483 , G01N33/52 , G01N2021/7786
摘要： Devices, methods, and kits for measuring or otherwise evaluating the concentration of one or more analytes in a body fluid are described. The devices, methods, and/or kits may be non-invasive. In some variations, a method for measuring the concentration of an analyte in sweat of a subject may comprise contacting a colorimetric membrane with a skin surface of the subject so that the membrane collects a volume of sweat from the skin surface, and analyzing the colorimetric membrane to determine the concentration of the analyte in the collected volume of sweat.
摘要翻译：描述了用于测量或以其他方式评估体液中一种或多种分析物的浓度的装置，方法和试剂盒。装置，方法和/或试剂盒可以是非侵入性的。在一些变型中，用于测量受试者的汗液中的分析物浓度的方法可以包括使比色膜与受试者的皮肤表面接触，使得膜从皮肤表面收集一定体积的汗液，并且分析比色膜以确定收集的汗液体积中分析物的浓度。

2. 发明申请

WO2011008581A2 DEVICES, METHODS, AND KITS FOR DETERMINING ANALYTE CONCENTRATIONS 审中-公开
标题翻译：用于确定分析浓度的装置，方法和试剂盒
公开(公告)号：WO2011008581A2
公开(公告)日：2011-01-20
申请号：PCT/US2010/040845
申请日：2010-07-01
申请人： FREELANCE CORPORATION , FINKELSHTEIN, Irina, V. , MOYER, James, W. , POTTS, Russel, O. , SAGE, Burton, H. , SHARTLE, Robert, J. , WILSON, Donald, R. , WONG, Bruce, D.
发明人： FINKELSHTEIN, Irina, V. , MOYER, James, W. , POTTS, Russel, O. , SAGE, Burton, H. , SHARTLE, Robert, J. , WILSON, Donald, R. , WONG, Bruce, D.
IPC分类号： G01N33/48 , G01N33/487 , G01N21/25 , G01N21/78 , G01N33/52
CPC分类号： C12Q1/006 , A61B5/14517 , A61B5/14532 , A61B5/1455 , A61B10/0064 , G01N21/78 , G01N21/8483 , G01N33/52 , G01N2021/7786
摘要： Devices, methods, and kits for measuring or otherwise evaluating the concentration of one or more analytes in a body fluid are described. The devices, methods, and/or kits may be non-invasive. In some variations, a method for measuring the concentration of an analyte in sweat of a subject may comprise contacting a colorimetric membrane with a skin surface of the subject so that the membrane collects a volume of sweat from the skin surface, and analyzing the colorimetric membrane to determine the concentration of the analyte in the collected volume of sweat.
摘要翻译：描述了用于测量或以其它方式评价体液中的一种或多种分析物的浓度的装置，方法和试剂盒。装置，方法和/或试剂盒可以是非侵入性的。在一些变型中，用于测量受试者汗液中分析物浓度的方法可以包括使比色膜与受试者的皮肤表面接触，使得膜从皮肤表面收集体积的汗液，并分析比色膜以确定所收集体积的汗液中分析物的浓度。

3. 发明申请

WO2010030609A1 SWEAT COLLECTION DEVICES FOR GLUCOSE MEASUREMENT 审中-公开
标题翻译：用于葡萄糖测量的SWEAT收集装置
公开(公告)号：WO2010030609A1
公开(公告)日：2010-03-18
申请号：PCT/US2009/056265
申请日：2009-09-08
申请人： VIVOMEDICAL, INC. , POTTS, Russell, O. , MOYER, James, W. , YANAZAWA, Hiroshi , FINKELSHTEIN, Irina , YE, Shuying
发明人： POTTS, Russell, O. , MOYER, James, W. , YANAZAWA, Hiroshi , FINKELSHTEIN, Irina , YE, Shuying
IPC分类号： A61B5/00
CPC分类号： A61B5/6833 , A61B5/14521 , A61B5/14532 , A61B5/14865
摘要： Devices, methods, and kits for collecting sweat that has come to the surface of the skin are provided. The sweat may be collected for measuring sweat glucose levels. Because sweat glucose levels correlate to blood glucose levels, the provided devices, methods, and kits may be used by diabetic patients to non-invasively monitor blood glucose levels. Sweat collection devices may be attachable to the surface of the skin and may collect about one microliter or less of sweat. Because only a small, fixed volume of sweat may be collected, the sweat glucose level may be measured in a matter of minutes. Further, as a fixed volume of sweat is tested, inaccuracies due to estimates of the sweat volume being tested are less likely to cause an inaccurate glucose measurement.
摘要翻译：提供了收集到皮肤表面的汗液的装置，方法和试剂盒。可以收集汗液来测量汗水葡萄糖水平。由于汗葡萄糖水平与血糖水平相关，糖尿病患者可使用所提供的装置，方法和试剂盒非侵入性地监测血糖水平。汗液收集装置可以附着到皮肤表面，并且可以收集大约一微升或更少的汗液。因为只能收集少量固定量的汗液，所以可以在几分钟内测量出汗糖水平。此外，当测试固定体积的汗液时，由于测试的汗液体积的估计导致的不准确度不太可能导致不准确的葡萄糖测量。

4. 发明申请

WO2007146514A3 SYSTEM FOR MONITORING OF PATIENTS 审中-公开
标题翻译：系统监测患者
公开(公告)号：WO2007146514A3
公开(公告)日：2008-03-20
申请号：PCT/US2007068560
申请日：2007-05-09
申请人： VIVOMEDICAL INC , BERMAN HERBERT L , BLAIR ROBERT N , MOYER JAMES W , POTTS RUSSELL O
发明人： BERMAN HERBERT L , BLAIR ROBERT N , MOYER JAMES W , POTTS RUSSELL O
IPC分类号： A61B5/00 , A61K9/22 , G01N21/55
CPC分类号： A61B5/02028 , A61B5/002 , A61B5/0022 , A61B5/14532 , A61B5/1455 , A61B5/1477 , A61B5/1486 , A61B2560/0412 , G06F19/3418
摘要： A patient monitoring system implemented by a service provider for users via recording a patient's analytes measurements by non-invasively interrogating a skin patch placed upon the patient's skin surface. The system includes an input module to provide a device to measure analytes from a patient, such as a measurement of the blood glucose level. The measurement is shared among a plurality of output devices such as computers, personal digital assistants (PDAs), cellular phones, and pagers that are stationed or held by various users, such as doctors, patients, researchers, pharmacies, labs, and health insurers. In addition, behavioral attributes are recorded and correlated with the analytes measurements to generate a profile. The profile is selectively sent to output devices based on the user profile corresponding to the output device. Also, access to the profile is monitored by a security module that encrypts the profile to prevent access by un-authorized users.
摘要翻译：由服务提供商为用户实施的患者监测系统，其通过非侵入式询问放置在患者皮肤表面上的皮肤贴片来记录患者的分析物测量值。该系统包括输入模块，用于提供测量来自患者的分析物的装置，例如测量血糖水平。诸如医生，病人，研究人员，药房，实验室和健康保险公司等各种用户所驻扎或持有的多个输出设备如计算机，个人数字助理（PDA），蜂窝电话和寻呼机共享测量。。此外，记录行为属性并与分析物测量相关联以生成轮廓。基于与输出设备相对应的用户简档，该配置文件被选择性地发送到输出设备。此外，对配置文件的访问由加密配置文件以防止未授权用户访问的安全模块来监视。

5. 发明申请

WO2007146047A1 PATCHES, SYSTEMS, AND METHODS FOR NON-INVASIVE GLUCOSE MEASUREMENT 审中-公开
标题翻译：用于非入侵葡萄糖测量的配件，系统和方法
公开(公告)号：WO2007146047A1
公开(公告)日：2007-12-21
申请号：PCT/US2007/013392
申请日：2007-06-06
申请人： VIVOMEDICAL, INC. , PEYSER, Thomas, A. , POTTS, Russell, O. , BERMAN, Herbert, L. , MOYER, James, W. , KOUCHNIR, Mikhail, A. , BLAIR, Robert, N.
发明人： PEYSER, Thomas, A. , POTTS, Russell, O. , BERMAN, Herbert, L. , MOYER, James, W. , KOUCHNIR, Mikhail, A. , BLAIR, Robert, N.
IPC分类号： A61B5/00
CPC分类号： G01N33/66 , A61B5/14521 , A61B5/14532 , A61B5/1486 , A61B5/6833 , A61B10/0064 , A61B2560/0412 , A61B2562/0295
摘要： Described here are patches, systems, and methods for measuring glucose. In general, the patches comprise a microfluidic collection layer and a detector, and the systems comprise a patch and a measurement device. Some methods for measuring glucose comprise cleaning the skin surface, collecting sweat from the skin surface using a microfluidic collection device, and measuring the collected glucose. Other methods comprise cleaning the skin surface, collecting sweat in a patch comprising a microfludic collection layer, and measuring glucose collected in the patch. Still other methods comprise cleaning the skin surface, collecting a first sweat sample from the skin surface in a patch comprising a microfludic collection layer and a detector layer, transferring the first sweat sample from the collection layer to the detector layer, measuring glucose in the first sweat sample, and repeating the collection, transferring, and measuring steps at least once.
摘要翻译：这里描述了用于测量葡萄糖的补丁，系统和方法。通常，贴片包括微流体收集层和检测器，并且系统包括贴片和测量装置。用于测量葡萄糖的一些方法包括清洁皮肤表面，使用微流体收集装置从皮肤表面收集汗液，并测量收集的葡萄糖。其他方法包括清洁皮肤表面，在包含微量收集层的贴片中收集汗液，以及测量在贴片中收集的葡萄糖。还有其它方法包括清洁皮肤表面，在包括微量收集层和检测器层的贴片中从皮肤表面收集第一汗液样品，将第一汗液样品从收集层转移到检测器层，测量第一汗液样品中的葡萄糖汗液样品，并重复收集，转移和测量步骤至少一次。

6. 发明申请

WO2006007472B1 NON-INVASIVE GLUCOSE MEASUREMENT 审中-公开
标题翻译：非入侵葡萄糖测量
公开(公告)号：WO2006007472B1
公开(公告)日：2006-07-06
申请号：PCT/US2005022139
申请日：2005-06-22
申请人： VIVOMEDICAL INC , PEYSER THOMAS A , POTTS RUSSEL O , BERMAN HERBERT L , MOYER JAMES W , KOUCHNIR MIKHAIL A
发明人： PEYSER THOMAS A , POTTS RUSSEL O , BERMAN HERBERT L , MOYER JAMES W , KOUCHNIR MIKHAIL A
IPC分类号： A61B5/00 , A61B10/00 , C12Q1/54 , G01N33/50
CPC分类号： A61B5/1455 , A61B5/14521 , A61B5/14532 , A61B2562/0295 , G01N33/66
摘要： Described are devices, methods, and kits for non-invasively measuring glucose. In general, the devices comprise skin patches for placement on a skin surface and measurement devices for measuring glucose collected in the patches. The patches may include an adhesive material, a collection layer, an interface layer, and a sweat-permeable membrane. The sweat-permeable membrane is configured to act as a barrier to epidermal contaminants and glucose brought to the skin surface via diffusion. In this way, non-correlatable skin surface glucose will not be measured. The patches may further include components to induce a local sweat response. The measurement device typically includes a display, a processor, and a measurement mechanism. The methods typically include the steps of wiping the skin surface with a wipe containing at least one solvent for removing glucose, placing a patch on a skin surface, and measuring glucose collected in the patch. Kits comprising the patch and measurement device are also described.
摘要翻译：描述了用于非侵入性测量葡萄糖的装置，方法和试剂盒。通常，这些装置包括用于放置在皮肤表面上的皮肤贴片和用于测量在贴片中收集的葡萄糖的测量装置。贴剂可以包括粘合剂材料，收集层，界面层和汗液渗透膜。透汗膜构造成作为通过扩散带到皮肤表面的表皮污染物和葡萄糖的屏障。以这种方式，不能测量不相关的皮肤表面葡萄糖。补片还可以包括诱导局部汗水反应的组件。测量装置通常包括显示器，处理器和测量机构。所述方法通常包括以下步骤：用含有至少一种用于去除葡萄糖的溶剂的擦拭物擦拭皮肤表面，将贴片置于皮肤表面上，并测量在贴剂中收集的葡萄糖。还描述了包括贴片和测量装置的套件。

7. 发明申请

WO2006007472A3 NON-INVASIVE GLUCOSE MEASUREMENT 审中-公开
标题翻译：非侵入性的葡萄糖测量
公开(公告)号：WO2006007472A3
公开(公告)日：2006-06-08
申请号：PCT/US2005022139
申请日：2005-06-22
申请人： VIVOMEDICAL INC , PEYSER THOMAS A , POTTS RUSSEL O , BERMAN HERBERT L , MOYER JAMES W , KOUCHNIR MIKHAIL A
发明人： PEYSER THOMAS A , POTTS RUSSEL O , BERMAN HERBERT L , MOYER JAMES W , KOUCHNIR MIKHAIL A
IPC分类号： A61B5/00 , A61B10/00 , C12Q1/54 , G01N33/50
CPC分类号： A61B5/1455 , A61B5/14521 , A61B5/14532 , A61B2562/0295 , G01N33/66
摘要： Described are devices, methods, and kits for non-invasively measuring glucose. In general, the devices comprise skin patches for placement on a skin surface and measurement devices for measuring glucose collected in the patches. The patches may include an adhesive material, a collection layer, an interface layer, and a sweat-permeable membrane. The sweat-permeable membrane is configured to act as a barrier to epidermal contaminants and glucose brought to the skin surface via diffusion. In this way, non-correlatable skin surface glucose will not be measured. The patches may further include components to induce a local sweat response. The measurement device typically includes a display, a processor, and a measurement mechanism. The methods typically include the steps of wiping the skin surface with a wipe containing at least one solvent for removing glucose, placing a patch on a skin surface, and measuring glucose collected in the patch. Kits comprising the patch and measurement device are also described.
摘要翻译：描述了用于无创测量葡萄糖的装置，方法和试剂盒。通常，这些装置包括用于放置在皮肤表面上的皮肤贴片和用于测量在贴片中收集的葡萄糖的测量装置。贴片可以包括粘合材料，收集层，界面层和汗液可渗透膜。汗渗透膜被配置成充当对表皮污染物和葡萄糖经由扩散而带到皮肤表面的屏障。以这种方式，不可测量不可相关的皮肤表面葡萄糖。贴片可进一步包括诱导局部汗液反应的组分。测量装置通常包括显示器，处理器和测量机构。该方法通常包括用含有至少一种溶剂的擦拭物擦拭皮肤表面以去除葡萄糖，将贴片放置在皮肤表面上，并测量在贴片中收集的葡萄糖的步骤。还描述了包含贴片和测量装置的套件。

8. 发明申请

WO2009025698A1 DEVICES, SYSTEMS, AND METHODS FOR THE MEASUREMENT OF ANALYTES 审中-公开
标题翻译：用于测量分析仪的设备，系统和方法
公开(公告)号：WO2009025698A1
公开(公告)日：2009-02-26
申请号：PCT/US2008/007932
申请日：2008-06-25
申请人： VIVOMEDICAL, INC. , POTTS, Russell, O. , MOYER, James, W.
发明人： POTTS, Russell, O. , MOYER, James, W.
IPC分类号： A61B10/00 , A61B5/00
CPC分类号： A61B5/1486 , A61B5/14514 , A61B5/14521 , A61B5/14532 , A61B5/1455 , A61B5/1491 , A61B5/4266 , A61B5/4881 , A61B5/6833 , A61B5/6896 , A61B10/0064 , A61B2562/0295
摘要： Devices, systems, and methods for measuring analytes such as glucose are described herein. Some variations of the systems described herein are configured to collect sweat, and comprise a sweat collection device comprising a gradient and defining a collection location, where the gradient is configured to direct sweat toward the collection location when the sweat collection device is applied to a skin surface. Certain variations of the methods described herein comprise applying a system comprising a sweat collection device to a skin surface, where the sweat collection device comprises a gradient configured to direct sweat toward a collection location.
摘要翻译：本文描述了用于测量分析物（例如葡萄糖）的装置，系统和方法。本文描述的系统的一些变型被配置为收集汗液，并且包括汗液收集装置，其包括梯度并限定收集位置，其中渐变被配置为当将汗液收集装置施加到皮肤时将汗液引向收集位置表面。本文描述的方法的某些变型包括将包括汗液收集装置的系统应用于皮肤表面，其中汗液收集装置包括被配置为将汗液引向收集位置的渐变。

9. 发明申请

WO2010045247A1 SWEAT GLUCOSE SENSORS AND COLLECTION DEVICES FOR GLUCOSE MEASUREMENT 审中-公开
标题翻译：用于葡萄糖测量的SWEAT GLUCOSE传感器和收集装置
公开(公告)号：WO2010045247A1
公开(公告)日：2010-04-22
申请号：PCT/US2009/060528
申请日：2009-10-13
申请人： VIVOMEDICAL, INC. , POTTS, Russell, O. , MOYER, James, W.
发明人： POTTS, Russell, O. , MOYER, James, W.
IPC分类号： A61B5/00
CPC分类号： A61B5/14532 , A61B5/14521 , A61B5/1486 , A61B5/6833 , A61B10/0064 , A61B2562/0295 , A61B2562/125
摘要： A sweat glucose sensor for determining the glucose concentration in a volume of sweat is disclosed. The sweat glucose sensor may comprise two or more electrodes in contact with sweat in a container defined by two or more layers of a skin patch. The container may additionally contain a glucose enzyme that reacts with glucose in sweat collected by the container. The reaction of the glucose in the sweat with the glucose enzyme may affect an electrical signal passed by the two or more electrodes. The electrical signal may then be used to determine a sweat glucose concentration. The sweat glucose sensor may comprise two or more fill electrodes, also positioned to contact sweat collected by the container. The fill electrodes may be used, for example, to determine whether the skin patch contains a requisite volume of sweat to perform an accurate glucose measurement. Devices, methods, and kits for collecting sweat that has come to a skin surface are also disclosed.
摘要翻译：公开了一种用于测定一定体积汗液中葡萄糖浓度的汗葡萄糖传感器。汗葡萄糖传感器可以包括两个或更多个与由两层或更多层皮肤贴片限定的容器中的汗液接触的电极。容器还可以含有与容器收集的汗液中的葡萄糖反应的葡萄糖酶。汗液中的葡萄糖与葡萄糖酶的反应可能影响由两个或多个电极通过的电信号。然后可以使用电信号来确定汗葡萄糖浓度。汗葡萄糖传感器可以包括两个或更多个填充电极，其也定位成接触容器收集的汗液。例如，填充电极可以用于确定皮肤贴片是否含有必需的汗液体积以执行准确的葡萄糖测量。还公开了用于收集已经到达皮肤表面的汗液的装置，方法和试剂盒。

10. 发明申请

WO2007146514A2 SYSTEM FOR MONITORING OF PATIENTS 审中-公开
标题翻译：系统监测患者
公开(公告)号：WO2007146514A2
公开(公告)日：2007-12-21
申请号：PCT/US2007/068560
申请日：2007-05-09
申请人： VIVOMEDICAL, INC. , BERMAN, Herbert, L. , BLAIR, Robert, N. , MOYER, James, W. , POTTS, Russell, O.
发明人： BERMAN, Herbert, L. , BLAIR, Robert, N. , MOYER, James, W. , POTTS, Russell, O.
IPC分类号： A61B5/05 , A61B5/00
CPC分类号： A61B5/02028 , A61B5/002 , A61B5/0022 , A61B5/14532 , A61B5/1455 , A61B5/1477 , A61B5/1486 , A61B2560/0412 , G06F19/00 , G06F19/3418
摘要： A patient monitoring system implemented by a service provider for users via recording a patient's analytes measurements by non-invasively interrogating a skin patch placed upon the patient's skin surface. The system includes an input module to provide a device to measure analytes from a patient, such as a measurement of the blood glucose level. The measurement is shared among a plurality of output devices such as computers, personal digital assistants (PDAs), cellular phones, and pagers that are stationed or held by various users, such as doctors, patients, researchers, pharmacies, labs, and health insurers. In addition, behavioral attributes are recorded and correlated with the analytes measurements to generate a profile. The profile is selectively sent to output devices based on the user profile corresponding to the output device. Also, access to the profile is monitored by a security module that encrypts the profile to prevent access by un-authorized users.
摘要翻译：由服务提供商为用户实施的患者监测系统，其通过非侵入式询问放置在患者皮肤表面上的皮肤贴片来记录患者的分析物测量值。该系统包括输入模块，用于提供测量来自患者的分析物的装置，例如测量血糖水平。诸如医生，病人，研究人员，药房，实验室和健康保险公司等各种用户所驻扎或持有的多个输出设备如计算机，个人数字助理（PDA），蜂窝电话和寻呼机共享测量。。此外，记录行为属性并与分析物测量相关联以生成轮廓。基于与输出设备相对应的用户简档，该配置文件被选择性地发送到输出设备。此外，对配置文件的访问由加密配置文件以防止未授权用户访问的安全模块来监视。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式