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    • 4. 发明专利
    • Improvements in Thermal Switches.
    • GB191220464A
    • 1913-07-03
    • GB191220464D
    • 1912-09-09
    • MCPHERSON ANDREW
    • MCPHERSON ANDREW
    • H01H71/20
    • 20,464. McPherson, A. Sept. 9. Automatic circuit-breakers; thermal cut-outs. -A switch is opened automatically by a spring in consequence of the heating effect of the current upon another spring which is located in the circuit and normally helps to maintain the switch closed. An arm pivoted at 3 is jointed at 4 to another arm carrying the movable contact 6 which touches the fixed contact 5 when the two arms lie in a straight line. A fixed stop 9 lies at one end of a slot 7 in the arm 6, and the two arms are acted upon by springs 11, 13, respectively, which normally keep the parts in the position shown. The spring 11, traversed by the circuit current, slackens when the current is excessive, and the preponderating action of the other spring then breaks the circuit, the arms moving to the dotted-line position. To prevent the spring 11 from being unduly stretched, it is arranged to work in a slot 8 and is fitted with a retracting- spring 15. The switch may be provided with a handle for resetting.
    • 8. 发明申请
    • PYRROLOPYRIMIDINE COMPOUNDS AND THEIR USE AS JANUS KINASE MODULATORS
    • 吡咯啉化合物及其作为JANUS KINASE调节剂的用途
    • WO2009049028A1
    • 2009-04-16
    • PCT/US2008/079315
    • 2008-10-09
    • TARGEGEN INC.NORONHA, GlennCAO, JianguoCHOW, Chun, P.MAK, Chi ChingPALANKI, Moorthy, S.S.DNEPROVSKAIA, ElenaMCPHERSON, AndrewPATHAK, Ved, PrakashRENICK, JoelZENG, Binqi
    • NORONHA, GlennCAO, JianguoCHOW, Chun, P.MAK, Chi ChingPALANKI, Moorthy, S.S.DNEPROVSKAIA, ElenaMCPHERSON, AndrewPATHAK, Ved, PrakashRENICK, JoelZENG, Binqi
    • C07D487/04C07D519/00A61K31/519
    • C07D487/04
    • Provided herein are pyrrolopyrimidine compounds of Formula (I) wherein R1 is a heteroaryl containing at least one S atom, and optionally substituted on a ring carbon by one, two, or three substituents each independently selected from the group consisting of : halo, hydroxyl, nitro, formyl, formamido, cyano, sulfonyl, carboxy, amino, amido, acylamino, carbamoyl, sulphamoyl, alkyl, alkenyl, CF3, ureido, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, carbaldehyde oxime, N -alkylsulphamoyl, N-alkylcarbamoyl, -OR13R11 or -R13R11; R2 is phenyl or pyridinyl, wherein R2 optionally substituted on a ring carbon by one, two, or three substituents each indenpendently selected from the group consisting of : halo, hydroxyl, cyano, nitro, formyl, formamido, carboxy, sulfonyl, amino, amido, -N- alkyl -amino, carbamoyl, sulphamoyl, CF3, ureido, alkyl, alkenyl, alkynyl, alkoxy, alkanoyl, alkoxycarbonyl, N-alkylsulphamoyl, N-alkylcarbamoyl, -OR11, -OR12R11, or -R12R11; and methods of making and using the same. Such compounds may be used in inflammatory or myeloproliferative disorders. The disclosure also provides for treating cancer.
    • 本文提供了式(I)的吡咯并嘧啶化合物,其中R 1是含有至少一个S原子的杂芳基,并且任选地在环碳上被一个,两个或三个取代基取代,所述取代基各自独立地选自:卤素,羟基, 硝基,甲酰基,甲酰氨基,氰基,磺酰基,羧基,氨基,酰氨基,酰氨基,氨基甲酰基,氨磺酰基,烷基,烯基,CF 3,脲基,炔基,烷氧基,烷酰基,烷氧羰基,甲醛肟,N-烷基氨磺酰,N-烷基氨基甲酰基, OR13R11或-R13R11; R2是苯基或吡啶基,其中R2任选地在环碳上被一个,两个或三个取代基取代,每个独立地选自:卤素,羟基,氰基,硝基,甲酰基,甲酰氨基,羧基,磺酰基,氨基,酰氨基 ,-N-烷基氨基,氨基甲酰基,氨磺酰基,CF 3,脲基,烷基,烯基,炔基,烷氧基,烷酰基,烷氧基羰基,N-烷基氨磺酰基,N-烷基氨基甲酰基,-OR 11,-OR 12 R 11或-R 12 R 11; 以及制作和使用它们的方法。 这些化合物可用于炎性或骨髓增生性疾病。 本公开还提供治疗癌症。
    • 10. 发明申请
    • MULTI-TOUCH PIANO KEYBOARD
    • 多触摸PIANO键盘
    • WO2013006746A1
    • 2013-01-10
    • PCT/US2012/045649
    • 2012-07-06
    • DREXEL UNIVERSITYMCPHERSON, AndrewKIM, Youngmoo
    • MCPHERSON, AndrewKIM, Youngmoo
    • G10H1/02G10H1/34
    • G10H7/06G06F3/044G06F2203/04104G10H1/02G10H1/344G10H2220/221G10H2220/275
    • A musical keyboard touch sensor pad having a plurality of integrated sensors disposed in an array is disclosed. The plurality of integrated sensors represents a keyboard key. A processor is electronically coupled to the plurality of integrated sensors. The processor is programmed to receive signals from several of the plurality of integrated sensors and to generate a sound signal based on input from the several of the plurality of integrated sensors. The output is variable based on the number in the plurality and the location of the plurality in the array. An audio output device is electronically coupled to the processor to generate a sound based on the sound signal. A keyboard using a plurality of the sensor pads as well as a method of generating sounds from the keyboard are also disclosed.
    • 公开了一种具有设置在阵列中的多个集成传感器的音乐键盘触摸传感器垫。 多个集成传感器表示键盘键。 处理器电耦合到多个集成传感器。 处理器被编程为从多个集成传感器中的若干个传感器接收信号,并根据来自多个集成传感器中的几个的输入产生声音信号。 基于多个中的数字和阵列中的多个的位置,输出是可变的。 音频输出设备电连接到处理器以基于声音信号产生声音。 还公开了使用多个传感器焊盘的键盘以及从键盘产生声音的方法。