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1. 发明申请

US20130068632A1 METHODS AND APPARATUS FOR NANOMEMBRANE-BASED NUCLEIC ACID SENSING PLATFORM FOR PORTABLE DIAGNOSTICS 审中-公开
标题翻译：用于便携式诊断的基于纳米骨质系统的核酸感测平台的方法和装置
公开(公告)号：US20130068632A1
公开(公告)日：2013-03-21
申请号：US13476783
申请日：2012-05-21
申请人： Hsueh-Chia Chang , Zdenek Slouka , Satyajyoti Senapati , Li-Jing Cheng
发明人： Hsueh-Chia Chang , Zdenek Slouka , Satyajyoti Senapati , Li-Jing Cheng
IPC分类号： G01N27/414
CPC分类号： G01N27/44704 , B82Y30/00 , G01N27/3278 , G01N27/4146
摘要： A DNA/RNA detection technology is provided. The open flow detection technique includes a substrate defining a pair of opposing microchannels, a pair of opposing electrodes in the opposing microchannels, and at least one ion exchanging nanomembrane coupled between the opposing microchannels such that the opposing microchannels are connected to each other only through the nanomembrane, wherein the nanomembrane is functionalized with a probe complementary to the macromolecule. A voltammeter is provided to measure the electrical current or potential across the nanomembrane, and detect a change in the measured electrical current or potential to quantify the presence of the macromolecule
摘要翻译：提供DNA / RNA检测技术。开放流量检测技术包括限定一对相对的微通道的衬底，相对的微通道中的一对相对的电极，以及耦合在相对的微通道之间的至少一个离子交换纳米膜，使得相对的微通道仅通过纳米膜，其中纳米膜用与大分子互补的探针功能化。提供伏特计来测量纳米膜上的电流或电位，并检测所测量的电流或电位的变化以量化大分子的存在

2. 发明授权

US06432758B1 Recrystallization method of polysilicon film in thin film transistor 失效
标题翻译：薄膜晶体管中多晶硅薄膜的重结晶方法
公开(公告)号：US06432758B1
公开(公告)日：2002-08-13
申请号：US09781431
申请日：2001-02-13
申请人： Huang-Chung Cheng , Ching-Wei Lin , Li-Jing Cheng
发明人： Huang-Chung Cheng , Ching-Wei Lin , Li-Jing Cheng
IPC分类号： H01L2100
CPC分类号： H01L21/00 , H01L29/66757 , H01L29/78675
摘要： The present invention proposes a crystallization method of the poly-Si thin film in a thin film transistor. A substrate having an insulator layer is provided. An amorphous silicon layer or a micro-crystalline silicon layer having two thickness is first formed on the insulator layer. The region of thinner is defined as the channel region of the TFT, while the region of thicker can be defined as the source/drain regions of the TFT. Next, an excimer laser is used for crystallization. During the excimer laser irradiation, the amorphous silicon layer of thinner is completely melted, and the amorphous silicon layer of thicker is partially melted. The partially melted amorphous silicon layer is used as crystallization seeds. Through formation of the temperature gradient between the completely melted amorphous silicon layer and the partially melted amorphous silicon layer, longitudinal growth of silicon grains in the completely melted region will be performed to grow a poly-Si layer having good homogeneity and large grains.
摘要翻译：本发明提出了薄膜晶体管中的多晶硅薄膜的结晶方法。提供具有绝缘体层的基板。首先在绝缘体层上形成具有两个厚度的非晶硅层或微晶硅层。较薄的区域被定义为TFT的沟道区域，而较厚的区域可以被定义为TFT的源极/漏极区域。接下来，使用准分子激光器进行结晶。在准分子激光照射期间，较薄的非晶硅层完全熔化，较厚的非晶硅层部分熔化。部分熔融的非晶硅层用作结晶种子。通过形成完全熔融的非晶硅层和部分熔融的非晶硅层之间的温度梯度，将完成完全熔融区域中的硅晶粒的纵向生长，以生长具有良好均匀性和大晶粒的多晶硅层。

3. 发明授权

US07344847B2 Nanoscale patterning and immobilization of bio-molecules 有权
标题翻译：生物分子的纳米图案化和固定化
公开(公告)号：US07344847B2
公开(公告)日：2008-03-18
申请号：US11066804
申请日：2005-02-25
申请人： Alan J. Hunt , Lingjie J. Guo , Jeremy Damon Hoff , Li-Jing Cheng , Edgar Meyhofer
发明人： Alan J. Hunt , Lingjie J. Guo , Jeremy Damon Hoff , Li-Jing Cheng , Edgar Meyhofer
IPC分类号： G01N33/53 , H01C17/075 , C23C22/00
CPC分类号： G01N33/54366 , B01J19/0046 , B01J2219/00382 , B01J2219/00385 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00617 , B01J2219/0063 , B01J2219/00632 , B01J2219/00635 , B01J2219/00659 , B01J2219/00722 , B01J2219/00725 , B82Y10/00 , B82Y30/00 , B82Y40/00 , G03F7/0002
摘要： A support for immobilizing target molecules comprises a substrate having a plurality of binding regions for binding select target molecules, with target-molecule-capturing agent immobilized at the binding regions. The binding regions are intersperse among other non-binding regions. The binding regions are of sub-micron size, have high selectivity and high binding capacity, and prevent or at least minimize loss of target molecule activity.
摘要翻译：用于固定靶分子的载体包括具有多个用于结合选择性靶分子的结合区域的底物和固定在结合区域的靶分子捕获剂。结合区域在其他非结合区域之间是散在的。结合区具有亚微米尺寸，具有高选择性和高结合能力，并且防止或至少最小化靶分子活性的损失。

4. 发明申请

US20060194252A1 Nanoscale patterning and immobilization of bio-molecules 有权
标题翻译：生物分子的纳米图案化和固定化
公开(公告)号：US20060194252A1
公开(公告)日：2006-08-31
申请号：US11066804
申请日：2005-02-25
申请人： Alan Hunt , Lingjie Guo , Jeremy Hoff , Li-Jing Cheng , Edgar Meyhofer
发明人： Alan Hunt , Lingjie Guo , Jeremy Hoff , Li-Jing Cheng , Edgar Meyhofer
IPC分类号： G01N33/53 , C12M1/34
CPC分类号： G01N33/54366 , B01J19/0046 , B01J2219/00382 , B01J2219/00385 , B01J2219/00596 , B01J2219/00605 , B01J2219/00612 , B01J2219/00617 , B01J2219/0063 , B01J2219/00632 , B01J2219/00635 , B01J2219/00659 , B01J2219/00722 , B01J2219/00725 , B82Y10/00 , B82Y30/00 , B82Y40/00 , G03F7/0002
摘要： A support for immobilizing target molecules comprises a substrate having a plurality of binding regions for binding select target molecules, with target-molecule-capturing agent immobilized at the binding regions. The binding regions are intersperse among other non-binding regions. The binding regions are of sub-micron size, have high selectivity and high binding capacity, and prevent or at least minimize loss of target molecule activity.
摘要翻译：用于固定靶分子的载体包括具有多个用于结合选择性靶分子的结合区域的底物和固定在结合区域的靶分子捕获剂。结合区域在其他非结合区域之间是散在的。结合区具有亚微米尺寸，具有高选择性和高结合能力，并且防止或至少最小化靶分子活性的损失。

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