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    • 1. 发明申请
    • A NOVEL ANTI-AGING SKINCARE CREAM, THE COSMETIC DEVICE AND CREAM WITHIN
    • 一种新型抗衰老皮肤霜,化妆品和奶油
    • WO2009132585A1
    • 2009-11-05
    • PCT/CN2009/071549
    • 2009-04-29
    • YOLARE DERMACEUTICALS, LLC.LAN, HuangYONG, CangJOSE, Renato
    • LAN, HuangYONG, CangJOSE, Renato
    • C07K5/097C07K5/083A61K8/64A61Q19/08A61N5/06
    • A61K8/64A61K38/06A61K2800/782A61N5/0616A61N2005/0647A61N2005/0652A61N2005/0662A61Q19/08C07K5/06043C07K5/0823
    • This invention reveals a novel skin-rejuvenating method that combines the application of light physics (a Light emitting diode (LED) device with specific wavelength, intensity, and pulsing frequency) and biochemistry (a specific collagenase inhibitor). The programmed LED light can penetrate skin epidermis and activate the fibroblasts in dermis to produce new collagen. Meanwhile, the overproduction of collagen leads to the feedback activation of collagenase, which degrades collagen and eliminates the beneficiary effects of LED light. Hence, this invention also includes a topical cream containing a certain lipophilic collagenase inhibitor, which, when used alone or in combination with the light device, can maintain high levels of skin collagen, and eventually achieve the long term effects of reducing wrinkles, enhancing skin elasticity, and diminishing eye bags and dark circles. The light device and active-containing cream have achieved positive effects when tested in human trials.
    • 本发明揭示了将光物理学(具有特定波长,强度和脉冲频率的发光二极管(LED)器件)和生物化学(特定胶原酶抑制剂)的应用组合的新型皮肤恢复方法。 编程的LED灯可以穿透皮肤表皮并激活真皮中的成纤维细胞以产生新的胶原蛋白。 同时,胶原蛋白过多产生胶原酶的反馈活化,胶原蛋白降解,消除了LED光的受益。 因此,本发明还包括含有某种亲脂性胶原酶抑制剂的局部乳膏,其当单独使用或与轻装置组合使用时,可以保持高水平的皮肤胶原蛋白,并且最终实现减少皱纹,增强皮肤的长期效果 弹性,眼袋和黑眼圈减少。 当在人体试验中进行测试时,光装置和含活性乳膏已经获得了积极的作用。
    • 4. 发明授权
    • System and method for providing a virtual binding for a worm storage system on rewritable media
    • 用于为可重写介质上的蠕虫存储系统提供虚拟绑定的系统和方法
    • US07747661B2
    • 2010-06-29
    • US11244269
    • 2005-10-05
    • Windsor Wee Sun HsuLan Huang
    • Windsor Wee Sun HsuLan Huang
    • G06F17/30G06F17/00
    • G06F21/6218
    • A virtual binding system ensures that the WORM logic for protecting data immutability cannot be circumvented, effectively guaranteeing WORM property of a WORM storage system composed of rewritable magnetic hard disks. To close the security hole between the rewritable media and the WORM logic, virtual binding securely authenticates the legitimacy of a WORM logic controller before granting data access on a WORM storage media. Furthermore, the system verifies the legitimacy of the WORM logic controller during data access. This approach virtually binds together the WORM logic controller and the WORM storage media even though the WORM logic controller and the WORM storage media may be physically separate.
    • 虚拟绑定系统确保不能避免用于保护数据不变性的WORM逻辑,有效地保证由可重写磁性硬盘组成的WORM存储系统的WORM属性。 要关闭可重写介质和WORM逻辑之间的安全漏洞,虚拟绑定安全地验证WORM逻辑控制器的合法性,然后授予WORM存储介质上的数据访问权限。 此外,系统在数据访问期间验证WORM逻辑控制器的合法性。 即使WORM逻辑控制器和WORM存储介质可能是物理上分离的,这种方式实际上将WORM逻辑控制器和WORM存储介质绑定在一起。
    • 5. 发明申请
    • STORAGE DEVICE BACKPLANE AND IDENTIFICATION CIRCUIT
    • 存储设备背板和识别电路
    • US20090154088A1
    • 2009-06-18
    • US12025505
    • 2008-02-04
    • Lan HuangShih-Hao Liu
    • Lan HuangShih-Hao Liu
    • G06F1/16H01R12/16H05K7/00
    • G06F13/409G06F13/4247
    • A storage device backplane and an identification circuit for identifying using situations of the storage device backplane are provided. The storage device backplane possesses a first connection interface and a second connection interface, for being used as a first backplane supporting a motherboard, or a second backplane cascaded to the first backplane, or a first backplane supporting a daughterboard of the motherboard. The first and second backplanes possess the same storage device backplane structure. If the storage device backplane is used as the first backplane, a first connection interface of the first backplane is coupled to the motherboard or the daughterboard thereof; if the storage device backplane is used as the second backplane, a first connection interface of the second backplane is coupled to a second connection interface of the first backplane. The identification circuit identifies using situations of the storage device backplane and display corresponding correct indicator number.
    • 提供了存储设备背板和用于识别存储设备背板的使用情况的识别电路。 存储设备背板具有第一连接接口和第二连接接口,用于作为支撑母板的第一背板或级联到第一背板的第二背板或支撑母板的子板的第一背板。 第一和第二背板具有相同的存储设备背板结构。 如果存储设备背板用作第一背板,则第一背板的第一连接接口耦合到主板或其母板; 如果存储设备背板用作第二背板,则第二背板的第一连接接口耦合到第一背板的第二连接接口。 识别电路识别存储设备背板的使用情况,并显示相应的正确指示器编号。
    • 7. 发明申请
    • Synthesis of (1)-beta-elemene, (-)-beta-elemenal, (-)-beta-elemenol, (-)-beta-elemene fluoride and their analogues, intermediates, and composition and uses thereof
    • ( - ) - β-榄香烯,( - ) - β-榄香烯,( - ) - β-榄香烯氟化物及其类似物,中间体及其组成和用途的合成
    • US20070135526A1
    • 2007-06-14
    • US11649558
    • 2007-01-04
    • Lan Huang
    • Lan Huang
    • A61K31/11A61K31/045A61K31/025A61K31/015
    • C07F9/65848C07C1/324C07C13/19C07C17/16C07C33/14C07C35/18C07C45/298C07C45/30C07C47/21C07C49/557C07C49/647C07C2601/14C07C2601/16C07C22/00C07C47/225
    • The present invention provides convergent processes for preparing (−)-beta-elemene, (−)-beta-elemenal, (−)-beta-elemenol, and (−)-beta-elemene fluoride and analogues thereof. Also provided are intermediates useful for preparing (−)-beta-elemene. The present invention further provides novel compositions based on analogues of (−)-beta-elemene, (−)-beta-elemenal, (−)-beta-elemenol, (−)-beta-elemene fluoride and methods for the treatment of cancer, such as brain tumor, lung cancer, breast cancer, prostate cancer, ovarian cancer, colorectal cancer, gastric intestional cancer, and stomach cancer. The inventors propose a combination therapy using 1) one or more of the following anti-cancer agents: including, but not limited to, Cisplatin, 5-FU, Taxol, Taxol derivatives, and any anti-cancer agent, and 2) one or more of the following (−)-beta-elemene and its analogs, including (−)-beta-elemene, (−)-beta-elemenal, (−)-beta-elemenol, (−)-beta-elemene fluoride, and their analogs, and (−)-beta-elemene's intermediate in its chemical synthesis, for the treatment of cancer, especially for the treatment of brain tumor, lung cancer, ovarian cancer, bladder cancer, cervical cancer, colon cancer, breast cancer, and prostate cancer.
    • 本发明提供( - ) - β-榄香烯,( - ) - β-元素,( - ) - β-榄香烯和( - ) - β-榄香烯氟化物及其类似物的收敛方法。 还提供了可用于制备( - ) - β-榄香烯的中间体。 本发明还提供了基于( - ) - β-榄香烯,( - ) - β-元素,( - ) - β-榄香烯,( - ) - β-榄香烯氟化物类似物和治疗癌症的新方法 ,如脑肿瘤,肺癌,乳腺癌,前列腺癌,卵巢癌,结肠直肠癌,胃肠癌和胃癌。 本发明人提出了使用以下1种或多种抗癌药物的组合疗法:包括但不限于顺铂,5-FU,紫杉醇,紫杉醇衍生物和任何抗癌剂,以及2)一种或多种 ( - ) - β-榄香烯及其类似物,包括( - ) - β-榄香烯,( - ) - β-元素,( - ) - β-榄香烯,( - ) - 他们的类似物和( - ) - β-榄香烯在其化学合成中的中间体,用于治疗癌症,特别是用于治疗脑肿瘤,肺癌,卵巢癌,膀胱癌,子宫颈癌,结肠癌,乳腺癌和 前列腺癌。
    • 9. 发明申请
    • System and method for providing a virtual binding for a worm storage system on rewritable media
    • 用于为可重写介质上的蠕虫存储系统提供虚拟绑定的系统和方法
    • US20070079146A1
    • 2007-04-05
    • US11244269
    • 2005-10-05
    • Windsor HsuLan Huang
    • Windsor HsuLan Huang
    • G06F12/14
    • G06F21/6218
    • A virtual binding system ensures that the WORM logic for protecting data immutability cannot be circumvented, effectively guaranteeing WORM property of a WORM storage system composed of rewritable magnetic hard disks. To close the security hole between the rewritable media and the WORM logic, virtual binding securely authenticates the legitimacy of a WORM logic controller before granting data access on a WORM storage media. Furthermore, the system verifies the legitimacy of the WORM logic controller during data access. This approach virtually binds together the WORM logic controller and the WORM storage media even though the WORM logic controller and the WORM storage media may be physically separate.
    • 虚拟绑定系统确保不能避免用于保护数据不变性的WORM逻辑,有效地保证由可重写磁性硬盘组成的WORM存储系统的WORM属性。 要关闭可重写介质和WORM逻辑之间的安全漏洞,虚拟绑定安全地验证WORM逻辑控制器的合法性,然后授予WORM存储介质上的数据访问权限。 此外,系统在数据访问期间验证WORM逻辑控制器的合法性。 即使WORM逻辑控制器和WORM存储介质可能是物理上分离的,这种方式实际上将WORM逻辑控制器和WORM存储介质绑定在一起。