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1. 发明公开

EP2995587A1 GRAPHENE MATERIAL AND METHOD OF PREPARING THE SAME 审中-公开
标题翻译：维多利亚州立大学DAVON
公开(公告)号：EP2995587A1
公开(公告)日：2016-03-16
申请号：EP15184220.0
申请日：2015-09-08
申请人： Liu, Jianhong
发明人： LIU, Jianhong , ZHANG, Qianling , HE, Chuanxin , XU, Jian , HU, Chao
IPC分类号： C01B31/04
CPC分类号： C01B31/0446 , C01B32/182 , C01B32/184
摘要： A method of preparing a graphene material. The method includes: (1) preparing a liquid polyacrylonitrile (LPAN) solution, stirring the LPAN solution to yield a cyclized polyacrylonitrile solution; (2) stirring the cyclized LPAN solution at between 200 and 300°C to yield a thermally-oxidized polyacrylonitrile; (3) grinding and sieving the thermally-oxidized polyacrylonitrile, and drying a resulting product at room temperature, to yield a thermally-oxidized precursor; (4) calcining the thermally-oxidized precursor in the presence of an inert gas flow of between 10 and 500 mL/min for between 1 and 24 hrs at the temperature of between 400 and 1000°C, to yield a carbonized precursor; and (5) calcining the carbonized precursor in the presence of an inert gas flow of between 10 and 500 mL/min for between 1 and 10 hrs at the temperature of between 1000 and 3000°C, to yield a graphene material.
摘要翻译：一种制备石墨烯材料的方法。该方法包括：（1）制备液态聚丙烯腈（LPAN）溶液，搅拌LPAN溶液，得到环化聚丙烯腈溶液; （2）在200-300℃之间搅拌环化的LPAN溶液，得到热氧化聚丙烯腈; （3）研磨和筛分热氧化聚丙烯腈，并在室温下干燥所得产物，得到热氧化前体; （4）在惰性气体流量为10-500mL / min的条件下，在400-1000℃的温度下煅烧热氧化的前体1至24小时，得到碳化前体; 和（5）在1000-3000℃的温度下，在10-500mL / min的惰性气体流动存在下煅烧碳化前体1至10小时，得到石墨烯材料。

2. 发明申请

WO2008012692A3 ASSAY FOR EFFICACY OF HISTONE DEACETYLASE INHIBITORS 审中-公开
标题翻译： HISTONE脱乙酰酶抑制剂效能测定
公开(公告)号：WO2008012692A3
公开(公告)日：2008-12-31
申请号：PCT/IB2007003186
申请日：2007-05-25
申请人： METHYLGENE INC , LI ZUOMEI , MAROUN CHRISTIANE R , LIU JIANHONG , BESTERMAN JEFFREY
发明人： LI ZUOMEI , MAROUN CHRISTIANE R , LIU JIANHONG , BESTERMAN JEFFREY
IPC分类号： C12Q1/68 , C12N9/16 , C12N9/99 , C12Q1/44 , G01N33/50 , G01N33/68
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158
摘要： The invention provides methods for assessing the efficacy of histone deacetylase inhibitors using biomarkers which can be used in human clinical trials and which are more quantitive, easy to be used and more relevant to clinical outcome for PD monitoring than existing assays. The method according to the invention utilizes biomarkers from blood cells from patients treated with HDAC inhibitors which are easy to assay.
摘要翻译：本发明提供了使用生物标志物评估组蛋白脱乙酰酶抑制剂的功效的方法，所述生物标志物可用于人类临床试验，并且比现有测定法更有量化，易于使用并且与PD监测的临床结果更相关。根据本发明的方法利用易于测定的用HDAC抑制剂治疗的患者的血细胞的生物标志物。

3. 发明申请

WO2014074753A1 ORAL CARE COMPOSITION CONTAINING THEAFLAVIN EXTRACT 审中-公开
标题翻译：口服护理组合物含有阿司匹林提取物
公开(公告)号：WO2014074753A1
公开(公告)日：2014-05-15
申请号：PCT/US2013/069013
申请日：2013-11-07
申请人： XIAOWEI, Shi , LI, Shiming , REN, Xueyin , LIU, Jianhong
发明人： LI, Shiming , REN, Xueyin , LIU, Jianhong
IPC分类号： A61K31/351 , A61K31/352 , A61K31/353
CPC分类号： A61K31/353 , A61K8/498 , A61K8/97 , A61K9/006 , A61K36/82 , A61Q11/00
摘要： A composition for oral use for the treatment and alleviation of bad breath and related oral health problems in humans and animals, including gigivitus, dental caries, periodontal disease, tooth desensitization and mainainance of the microorganism balance in the oral cavity. The invention comprises a composition containing i and oral health effective amount of theaflavins, an effective amount of a buffer, from about 40% to 99% by weight of one or more pharmaceutically acceptable water-soluble carriers, wherein the total water content of the oral composition is from about 5%to 20%. A method for making the inventive composition by extracting black tea and a method for use of the inventive composition are also disclosed.
摘要翻译：口腔用组合物，用于治疗和减轻人体和动物中的口臭和相关的口腔健康问题，包括口臭，牙龈，牙周病，牙齿脱敏和口腔中微生物平衡的维持。本发明包括含有i和口服健康有效量的茶黄素的组合物，有效量的缓冲剂，约40-99重量％的一种或多种药学上可接受的水溶性载体，其中口服的总含水量组成为约5％至20％。还公开了通过提取红茶制备本发明组合物的方法和本发明组合物的使用方法。

4. 发明申请

WO1996003105A1 PORTABLE MASSAGE APPARATUS 审中-公开
标题翻译：便携式按摩器
公开(公告)号：WO1996003105A1
公开(公告)日：1996-02-08
申请号：PCT/CN1995000060
申请日：1995-07-12
申请人： LIU, Jianhong
IPC分类号： A61H09/00
CPC分类号： A61H9/005 , A61H9/0007 , A61H9/0071
摘要： Portable massage apparatus by which pulsating air blow and suction is applied to human body comprises base (10), electromagnet (12), permanent magnets (11), levers (5), diaphragms (4), air casing (3), air tubes (2) and massage heads (1). The permanent magnets (11) are each fixed to the respective levers (5) on one end of the levers (5) and opposing or face the magnetic pole of the electromagnet (12), and the diaphragms (4) are each fixed to the respective levers (5) on another end of the levers (5) and sealed with the respective openings of the air casing (3). Ball bearings (7) are each fixed to the respective levers (5) between the ends of their longitudinal portions and mounted on a bearing base (9) which is mounted on the base (10).
摘要翻译：便携式按摩装置，其向人体施加脉动空气吹吸和抽吸，包括基座（10），电磁体（12），永磁体（11），杠杆（5），隔膜（4），空气壳体（3），空气管（2）和按摩头（1）。永磁体（11）各自固定在杠杆（5）的一端上的相应的杠杆（5）上，与电磁体（12）的磁极相对或面对，并且隔膜（4）各自固定到在杠杆（5）的另一端上的相应的杠杆（5）并且用空气壳体（3）的相应开口密封。滚珠轴承（7）各自固定在其纵向部分的端部之间的相应的杠杆（5）上，并安装在安装在基座（10）上的轴承座（9）上。

5. 发明申请

WO2008012692A2 ASSAY FOR EFFICACY OF HISTONE DEACETYLASE INHIBITORS 审中-公开
标题翻译：测定HISTONE DEACETYLASE抑制剂的功效
公开(公告)号：WO2008012692A2
公开(公告)日：2008-01-31
申请号：PCT/IB2007/003186
申请日：2007-05-25
申请人： METHYLGENE, INC. , LI, Zuomei , MAROUN, Christiane, R. , LIU, Jianhong , BESTERMAN, Jeffrey
发明人： LI, Zuomei , MAROUN, Christiane, R. , LIU, Jianhong , BESTERMAN, Jeffrey
CPC分类号： C12Q1/6883 , C12Q2600/106 , C12Q2600/136 , C12Q2600/158
摘要： The invention provides methods for assessing the efficacy of histone deacetylase inhibitors using biomarkers which can be used in human clinical trials and which are more quantitive, easy to be used and more relevant to clinical outcome for PD monitoring than existing assays. The method according to the invention utilizes biomarkers from blood cells from patients treated with HDAC inhibitors which are easy to assay.
摘要翻译：本发明提供了使用生物标志物评估组蛋白脱乙酰酶抑制剂的功效的方法，所述生物标志物可用于人临床试验，并且其更加定量，易于使用并且与PD监测的临床结果更相关现有的分析。根据本发明的方法利用来自用易于测定的HDAC抑制剂治疗的患者的血细胞的生物标志物。

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