专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2011088806A2 A METHOD OF INDUSTRIAL PRODUCTION OF AN AMORPHOUS FORM OF ATORVASTATIN WITH A HIGH SPECIFIC SURFACE AREA AND ITS USE IN A DOSAGE FORM 审中-公开
标题翻译：一种工业生产具有高比表面积的阿托伐他汀的非晶形式的方法及其在剂型中的用途
公开(公告)号：WO2011088806A2
公开(公告)日：2011-07-28
申请号：PCT/CZ2011000003
申请日：2011-01-12
申请人： ZENTIVA K S , STACH JAN , HOLAN MARTIN , HAVLICEK JAROSLAV , SIMEK STANISLAV , LINEK JAN , BRUSOVA HANA , RADL STANISLAV , DUBOVSKA MICHAELA , PROKOPOVA ALENA , RIHA JAROSLAV , SEBEK PAVEL
发明人： STACH JAN , HOLAN MARTIN , HAVLICEK JAROSLAV , SIMEK STANISLAV , LINEK JAN , BRUSOVA HANA , RADL STANISLAV , DUBOVSKA MICHAELA , PROKOPOVA ALENA , RIHA JAROSLAV , SEBEK PAVEL
IPC分类号： C07D207/34 , A61K31/40 , A61P3/06
CPC分类号： C07D207/34
摘要： The invention deals with an amorphous form of the hemicalcium salt of (3R,5R) 7-[3-phenyl- 4-phenylcarbamoyl-2-(4-fluorophenyl)-5-isopropylpyrrol-1-y1]-3,5-dihydroxyheptanoic acid (atorvastatin of formula I) with a high specific surface area, based on controlled precipitation, and its use in a medical dosage form. (I)
摘要翻译：本发明涉及（3R，5R）7- [3-苯基-4-苯基氨基甲酰基-2-（4-氟苯基）-5-异丙基吡咯-1-基] -3,5-二羟基庚酸的半钙盐基于受控沉淀的具有高比表面积的酸（式I的阿托伐他汀）及其在医药剂型中的用途。（一世）

2. 发明申请

WO2011088806A3 A METHOD OF INDUSTRIAL PRODUCTION OF AN AMORPHOUS FORM OF ATORVASTATIN WITH A HIGH SPECIFIC SURFACE AREA AND ITS USE IN A DOSAGE FORM 审中-公开
公开(公告)号：WO2011088806A3
公开(公告)日：2011-07-28
申请号：PCT/CZ2011/000003
申请日：2011-01-12
申请人： ZENTIVA, K.S. , STACH, Jan , HOLAN, Martin , HAVLICEK, Jaroslav , SIMEK, Stanislav , LINEK, Jan , BRUSOVA, Hana , RADL, Stanislav , DUBOVSKA, Michaela , PROKOPOVA, Alena , RIHA, Jaroslav , SEBEK, Pavel
发明人： STACH, Jan , HOLAN, Martin , HAVLICEK, Jaroslav , SIMEK, Stanislav , LINEK, Jan , BRUSOVA, Hana , RADL, Stanislav , DUBOVSKA, Michaela , PROKOPOVA, Alena , RIHA, Jaroslav , SEBEK, Pavel
IPC分类号： C07D207/34 , A61K31/40 , A61P3/06
摘要： The invention deals with an amorphous form of the hemicalcium salt of (3R,5R) 7-[3-phenyl- 4-phenylcarbamoyl-2-(4-fluorophenyl)-5-isopropylpyrrol-1-y1]-3,5-dihydroxyheptanoic acid (atorvastatin of formula I) with a high specific surface area, based on controlled precipitation, and its use in a medical dosage form. (I)

3. 发明申请

WO2010057449A3 A SOLID PHARMACEUTICAL COMPOSITION WITH ATORVASTATIN AND TELMISARTAN AS THE ACTIVE SUBSTANCES 审中-公开
标题翻译：以ATORVASTATIN和TELMISARTAN为活性物质的固体药物组合物
公开(公告)号：WO2010057449A3
公开(公告)日：2011-03-17
申请号：PCT/CZ2009000138
申请日：2009-11-16
申请人： ZENTIVA K S , PROKOPOVA ALENA , LINEK JAN , GRYCZOVA EVA
发明人： PROKOPOVA ALENA , LINEK JAN , GRYCZOVA EVA
IPC分类号： A61K9/16 , A61K9/20 , A61K31/00
CPC分类号： A61K31/40 , A61K9/2009 , A61K9/2018 , A61K9/2086 , A61K9/5084 , A61K31/4184 , A61K45/06 , A61K2300/00
摘要： A solid pharmaceutical composition with the active substances telmisartan and atorvastatin, characterized by in that both the substances are in the form of alkali or alkaline earth salts and the composition further contains an organic or inorganic base selected from the substances meglumine, sodium or potassium hydroxide, calcium or magnesium or sodium or potassium hydroxide, oxide or carbonate, and further polyvinyl pyrrolidone and a filler selected either from: a) a mono- or oligosaccharide soluble in water, or an alcoholic sugar, the size of 95% by weight of all particles of the filler, which may be present in the composition either individually or combined in larger granules, 99% by weight of which are smaller than 1.0 mm, being in the range of 0.025 to 0.355 mm; b) or a polysaccharide insoluble in water, 95% by weight of all particles of the filler, which may be present in the composition either individually or combined in large granules, 75% by weight of which are smaller than 0.50 mm, being smaller than 0.25 mm.
摘要翻译：一种具有活性物质替米沙坦和阿托伐他汀的固体药物组合物，其特征在于两种物质均为碱金属盐或碱土金属盐，组合物还含有选自葡甲胺，氢氧化钠或氢氧化钾的有机或无机碱，钙或镁或氢氧化钠或氢氧化钾或氢氧化钾或碳酸钾，以及另外的聚乙烯吡咯烷酮和填料，其选自：a）可溶于水的单糖或寡糖或醇糖，所述颗粒的大小为所有颗粒的95重量％的填料，其可以单独存在或组合成较大颗粒，其中99重量％小于1.0mm，在0.025至0.355mm的范围内; b）或不溶于水的多糖，95重量％的所有填料颗粒，其可以单独存在或组合在大颗粒中，75重量％小于0.50毫米，小于0.50毫米 0.25毫米。

4. 发明申请

WO2010057449A2 A SOLID PHARMACEUTICAL COMPOSITION WITH ATORVASTATIN AND TELMISARTAN AS THE ACTIVE SUBSTANCES 审中-公开
标题翻译：以ATORVASTATIN和TELMISARTAN为活性物质的固体药物组合物
公开(公告)号：WO2010057449A2
公开(公告)日：2010-05-27
申请号：PCT/CZ2009/000138
申请日：2009-11-16
申请人： ZENTIVA, K.S. , PROKOPOVA Alena , LINEK Jan , GRYCZOVA Eva
发明人： PROKOPOVA Alena , GRYCZOVA Eva
IPC分类号： A61K9/16 , A61K9/20 , A61K31/00
CPC分类号： A61K31/40 , A61K9/2009 , A61K9/2018 , A61K9/2086 , A61K9/5084 , A61K31/4184 , A61K45/06 , A61K2300/00
摘要： A solid pharmaceutical composition with the active substances telmisartan and atorvastatin, characterized by in that both the substances are in the form of alkali or alkaline earth salts and the composition further contains an organic or inorganic base selected from the substances meglumine, sodium or potassium hydroxide, calcium or magnesium or sodium or potassium hydroxide, oxide or carbonate, and further polyvinyl pyrrolidone and a filler selected either from: a) a mono- or oligosaccharide soluble in water, or an alcoholic sugar, the size of 95% by weight of all particles of the filler, which may be present in the composition either individually or combined in larger granules, 99% by weight of which are smaller than 1.0 mm, being in the range of 0.025 to 0.355 mm; b) or a polysaccharide insoluble in water, 95% by weight of all particles of the filler, which may be present in the composition either individually or combined in large granules, 75% by weight of which are smaller than 0.50 mm, being smaller than 0.25 mm.
摘要翻译：一种具有活性物质替米沙坦和阿托伐他汀的固体药物组合物，其特征在于两种物质均为碱金属盐或碱土金属盐，组合物还含有选自葡甲胺，氢氧化钠或氢氧化钾的有机或无机碱，钙或镁或氢氧化钠或氢氧化钾或氢氧化钾或碳酸钾，以及另外的聚乙烯吡咯烷酮和填料，其选自：a）可溶于水的单糖或寡糖或醇糖，所述颗粒的大小为所有颗粒的95重量％的填料，其可以单独存在或组合成较大颗粒，其中99重量％小于1.0mm，在0.025至0.355mm的范围内; b）或不溶于水的多糖，95重量％的所有填料颗粒，其可以单独存在或组合在大颗粒中，75重量％小于0.50毫米，小于0.50毫米 0.25毫米。

5. 发明专利

CS257865B1 CONNECTION FOR TIME INTERVALS MEASURING BY MEANS OF PROGRAMMABLE COUNTERS AND COMPUTER 未知
公开(公告)号：CS257865B1
公开(公告)日：1988-06-15
申请号：CS554185
申请日：1985-07-29
申请人： LINEK JAN
发明人： LINEK JAN
IPC分类号： G06F7/38

6. 发明专利

CS257867B3 CONNECTION FOR TIME INTERVALS MEASURING BY MEANS OF PROGRAMMABLE COUNTERS AND COMPUTER 未知
公开(公告)号：CS257867B3
公开(公告)日：1988-06-15
申请号：CS696685
申请日：1985-09-28
申请人： LINEK JAN , KONECNY IVAN
发明人： LINEK JAN , KONECNY IVAN
IPC分类号： G06F7/38

7. 发明专利

CS554185A1 ZAPOJENI PRE MERENI CASOVYCH INTERVALU PROGRAMOVATELNYNI CITACI A POCITACEM 未知
公开(公告)号：CS554185A1
公开(公告)日：1987-11-12
申请号：CS554185
申请日：1985-07-29
申请人： LINEK JAN ING
发明人： LINEK JAN ING
IPC分类号： G06F7/38

8. 发明专利

CS208933B1 CONNECTION FOR IDENTIFICATION CHARACTER RECOGNITION 未知
公开(公告)号：CS208933B1
公开(公告)日：1981-10-30
申请号：CS175078
申请日：1978-03-20
申请人： LINEK JAN , HELCL JIRI
发明人： LINEK JAN , HELCL JIRI
IPC分类号： G06V30/224 , G06K9/18

9. 发明专利

CS191595B1 CONNECTION FOR DETERMINATION OF THE PROFILE OF THE QUASISTATIONARY FLUID SURFACE 未知
公开(公告)号：CS191595B1
公开(公告)日：1979-07-31
申请号：CS160377
申请日：1977-03-10
申请人： LINEK JAN
发明人： LINEK JAN
IPC分类号： G01F23/00

10. 发明专利

CS696685A1 ZAPOJENI PRO MERENI CASOVYCH INTERVALU PROGRAMOVATELNYMI CITACI A POCITACEM 未知
公开(公告)号：CS696685A1
公开(公告)日：1987-11-12
申请号：CS696685
申请日：1985-09-28
申请人： LINEK JAN ING , KONECNY IVAN ING
发明人： LINEK JAN ING , KONECNY IVAN ING
IPC分类号： G06F7/38

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式