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1. 发明专利

IL253204A Trifluoroacetyl hydrazide compounds and methods of preparation and uses thereof 未知
公开(公告)号：IL253204A
公开(公告)日：2020-05-31
申请号：IL25320417
申请日：2017-06-27
申请人： GUANGZHOU MAGPIE PHARMACEUTICALS CO LTD , YUQIANG WANG , PEI YU , YEWEI SUN , ZAIJUN ZHANG , GAOXIAO ZHANG , LUCHEN SHAN , HAIYUN CHEN , LIANG TAO
发明人： YUQIANG WANG , PEI YU , YEWEI SUN , ZAIJUN ZHANG , GAOXIAO ZHANG , LUCHEN SHAN , HAIYUN CHEN , LIANG TAO
IPC分类号： A61K31/4965
摘要： The present invention relates to trifluoroacetyl hydrazide compounds and methods of preparation and uses thereof. The compounds have a structure of the following formula: The compounds showed multifunctional mechanisms, including inhibition of glutamate excitotoxicity, activation of MEF2 transcriptional activity, clearance of free radicals, and promotion of nerve differentiation, and has a better protective effect on cells especially nerve cells.. The compound can be used to prepare prophylactic or therapeutic medicaments with cytoprotective effects, for the prevention or treatment of diseases related to glutamate receptor activation, MEF2 disorders or excessive free radicals generation. The diseases include neurodegenerative diseases such as Alzheimer's disease, Parkinson and stroke, and the free radicals related diseases such as heart disease, myocardial ischemia, diabetes and other cardiovascular and cerebrovascular diseases.

2. 发明专利

AU2018101873A4 Ultra-wide band (UWB) based distance keeping system for autonomous mobile robot 未知
公开(公告)号：AU2018101873A4
公开(公告)日：2019-01-17
申请号：AU2018101873
申请日：2018-11-30
申请人： LIANG TAO MR
发明人： LIANG TAO
IPC分类号： G05D1/00 , B25J5/00
摘要： This invention provides a system that allows a mobile robot platform to keep fixed distance from a fixed or moving system that controls the dynamics of the robot platform, hereafter named target, such as a person, so that the mobile robot platform switches behavior between moving away from the target and moving towards the target. The mobile robot platform continuously measures the distance between itself and a target such as a person, via ultra-wide band (UWB) ranging system, and moves to and from the target based on the measurement. The invention provided herein, without limiting its generality, can be readily applied to create systems such as hands-free pushing trolley, hands free autonomous cooler, hands free lawn mower and hands-free wheelbarrow. Page 1 of 4 Drawings Hands free pushing system Keep distance 6 : Hands free following system Keep distance If TL 7 -TR 8 >0 then Target to left UWB tag 2 the target is at right anchor TL 7 side of the robot Target to right The robot turns to UWB anchor TR 8 right to face the Anchor target Front 3 UWB Anchor left(L) 4 UWB Anchor Right(R) 5 At least 3 anchors on robot 33

3. 发明专利

IL253204D0 Trifluoroacetyl hydrazide compounds and methods of preparation and uses thereof 未知
公开(公告)号：IL253204D0
公开(公告)日：2017-08-31
申请号：IL25320417
申请日：2017-06-27
申请人： GUANGZHOU MAGPIE PHARMACEUTICALS CO LTD , YUQIANG WANG , PEI YU , YEWEI SUN , ZAIJUN ZHANG , GAOXIAO ZHANG , LUCHEN SHAN , HAIYUN CHEN , LIANG TAO
发明人： YUQIANG WANG , PEI YU , YEWEI SUN , ZAIJUN ZHANG , GAOXIAO ZHANG , LUCHEN SHAN , HAIYUN CHEN , LIANG TAO
IPC分类号： A61K20060101
摘要： The present invention relates to trifluoroacetyl hydrazide compounds and methods of preparation and uses thereof. The compounds have a structure of the following formula: The compounds showed multifunctional mechanisms, including inhibition of glutamate excitotoxicity, activation of MEF2 transcriptional activity, clearance of free radicals, and promotion of nerve differentiation, and has a better protective effect on cells especially nerve cells.. The compound can be used to prepare prophylactic or therapeutic medicaments with cytoprotective effects, for the prevention or treatment of diseases related to glutamate receptor activation, MEF2 disorders or excessive free radicals generation. The diseases include neurodegenerative diseases such as Alzheimer's disease, Parkinson and stroke, and the free radicals related diseases such as heart disease, myocardial ischemia, diabetes and other cardiovascular and cerebrovascular diseases.

4. 发明申请

WO2018112165A1 METHODS FOR LIPID EXTRACTION AND IDENTIFICATION OF MICROBES USING SAME VIA MASS SPECTROMETRY 审中-公开
公开(公告)号：WO2018112165A1
公开(公告)日：2018-06-21
申请号：PCT/US2017/066342
申请日：2017-12-14
申请人： UNIVERSITY OF MARYLAND, BALTIMORE , GOODLETT, David R. , ERNST, Robert K. , LIANG, Tao , FONDRIE, William , NILSSON, Erik
发明人： GOODLETT, David R. , ERNST, Robert K. , LIANG, Tao , FONDRIE, William , NILSSON, Erik
IPC分类号： C11B1/10 , C11B1/02
CPC分类号： C11B1/02 , C11B1/10
摘要： A rapid lipid extraction protocol is provided. The protocol allows extraction of bacterial and fungal lipids from samples and purification of the same within one hour or less. The lipids produced using the protocol are of sufficient quality and purity that they can be analyzed using mass spectral analysis, and the data from such analysis can be used to identify the particular bacterial or fungal species from which the lipids are derived.

5. 发明申请

WO2006050286A3 AN APPARATUS AND METHOD FOR IMPROVING PRINTED CIRCUIT BOARD SIGNAL LAYER TRANSITIONS 审中-公开
公开(公告)号：WO2006050286A3
公开(公告)日：2006-05-11
申请号：PCT/US2005/039316
申请日：2005-10-27
申请人： INTEL CORPORATION , WIG, Timothy , LIANG, Tao
发明人： WIG, Timothy , LIANG, Tao
IPC分类号： H05K3/40 , H05K1/02
摘要： A method and apparatus for improving printed circuit board signal layer transitions are described. In one embodiment, the method includes the formation of a first via within a printed circuit board (PCB). A second via is formed concurrently within the PCB. In one embodiment, the second via is positioned proximate the first via to enable electromagnetic coupling between the first and second vias. Following formation of the second via, the first and second vias are connected to provide a series connection between the first and second vias. In one embodiment, the series connection between the first and second vias reduces a stub length with respect to the first via to reduce and potentially eliminate stub resonance for, for example, short signal layer transitions. Other embodiments are described and claimed.

6. 发明申请

WO2007109483A1 SHIFTED SEGMENT LAYOUT FOR DIFFERENTIAL SIGNAL TRACES TO MITIGATE BUNDLE WEAVE EFFECT 审中-公开
标题翻译：用于不同信号的移位部分布局以缓解整体效果
公开(公告)号：WO2007109483A1
公开(公告)日：2007-09-27
申请号：PCT/US2007/064015
申请日：2007-03-14
申请人： INTEL CORPORATION , LIANG, Tao , HALL, Stephen , HECK, Howard , BRIST, Gary , HORINE, Bryce
发明人： LIANG, Tao , HALL, Stephen , HECK, Howard , BRIST, Gary , HORINE, Bryce
IPC分类号： H05K3/46
CPC分类号： H05K1/0245 , H05K1/0366 , H05K2201/029 , H05K2201/09236
摘要： An article of manufacture includes a circuit board and a pair of traces on or in the circuit board. The pair of traces includes a first trace and a second trace. The first trace includes a first segment and a second segment continuously joined to the first segment. The first segment coincides with a first longitudinal axis. The second trace includes a first segment that runs alongside the first segment of the first trace. The second trace also includes a second segment that runs alongside the second segment of the first trace. The second segment of the second trace is continuously joined to the first segment of the second trace. The second segment of the second trace coincides with the first longitudinal axis.
摘要翻译：制造品包括电路板和电路板上或电路板中的一对迹线。该对轨迹包括第一轨迹和第二轨迹。第一迹线包括连续地连接到第一段的第一段和第二段。第一段与第一纵向轴线重合。第二个跟踪包括与第一个跟踪的第一个段一起运行的第一个段。第二轨迹还包括与第一轨迹的第二段一起运行的第二段。第二迹线的第二段连续地连接到第二迹线的第一段。第二轨迹的第二段与第一纵向轴线重合。

7. 发明申请

WO2006050286A2 AN APPARATUS AND METHOD FOR IMPROVING PRINTED CIRCUIT BOARD SIGNAL LAYER TRANSITIONS 审中-公开
标题翻译：改进印刷电路板信号层过渡的装置和方法
公开(公告)号：WO2006050286A2
公开(公告)日：2006-05-11
申请号：PCT/US2005039316
申请日：2005-10-27
申请人： INTEL CORP , WIG TIMOTHY , LIANG TAO
发明人： WIG TIMOTHY , LIANG TAO
CPC分类号： H05K1/115 , H05K1/0216 , H05K3/0047 , H05K3/3447 , H05K3/429 , H05K2201/09536 , H05K2201/09627 , H05K2203/0207 , Y10T29/49165
摘要： A method and apparatus for improving printed circuit board signal layer transitions are described. In one embodiment, the method includes the formation of a first via within a printed circuit board (PCB). A second via is formed concurrently within the PCB. In one embodiment, the second via is positioned proximate the first via to enable electromagnetic coupling between the first and second vias. Following formation of the second via, the first and second vias are connected to provide a series connection between the first and second vias. In one embodiment, the series connection between the first and second vias reduces a stub length with respect to the first via to reduce and potentially eliminate stub resonance for, for example, short signal layer transitions. Other embodiments are described and claimed.
摘要翻译：描述了用于改进印刷电路板信号层转变的方法和设备。在一个实施例中，该方法包括在印刷电路板（PCB）内形成第一通孔。在PCB内同时形成第二通孔。在一个实施例中，第二通路位于第一通路附近以实现第一通路和第二通路之间的电磁耦合。在形成第二通孔之后，第一和第二通孔被连接以提供第一和第二通孔之间的串联连接。在一个实施例中，第一和第二通孔之间的串联连接相对于第一通孔减小了短截线长度，以减少和潜在地消除例如短信号层转变的短截线谐振。描述并要求保护其他实施例。

8. 发明授权

US07214427B2 Composite beads comprising magnetizable substance and electro-conductive substance 有权
标题翻译：包含可磁化物质和导电物质的复合珠粒
公开(公告)号：US07214427B2
公开(公告)日：2007-05-08
申请号：US10104579
申请日：2002-03-21
申请人： Mingxian Huang , Lei Wu , Xiaobo Wang , Junquan Xu , Guo Liang Tao , Jing Cheng
发明人： Mingxian Huang , Lei Wu , Xiaobo Wang , Junquan Xu , Guo Liang Tao , Jing Cheng
IPC分类号： B32B5/16
CPC分类号： C40B70/00 , B01J19/0046 , B01J2219/00459 , B01J2219/005 , B01J2219/00545 , B01J2219/00551 , B01J2219/00585 , B01J2219/00596 , B01J2219/00655 , B01J2219/0072 , B01J2219/0074 , B03C1/02 , B03C5/026 , B03C5/028 , B82Y15/00 , C40B40/06 , C40B50/16 , G01N33/54326 , G01N33/588 , Y10S428/90 , Y10T428/2982 , Y10T428/2991 , Y10T428/32
摘要： This invention relates generally to the field of moiety or molecule isolation, detection and manipulation and library synthesis. In particular, the invention provides a bead, which bead comprises: a) a magnetizable substance; and b) an electrically conductive substance or an optical labeling substance. Methods and kits for isolating, detecting and manipulating moieties and synthesizing libraries using the beads are also provided.
摘要翻译：本发明一般涉及部分或分子分离，检测和操作以及文库合成领域。特别地，本发明提供了一种珠，该珠包括：a）可磁化物质; 和b）导电物质或光学标记物质。还提供了用于分离，检测和操作部分并使用珠的合成文库的方法和试剂盒。

9. 发明授权

US07262016B2 Microdevices having a preferential axis of magnetization and uses thereof 有权
标题翻译：具有优先磁化轴的微器件及其用途
公开(公告)号：US07262016B2
公开(公告)日：2007-08-28
申请号：US11230411
申请日：2005-09-20
申请人： Mingxian Huang , Lei Wu , Xiaobo Wang , Junquan Xu , Guo Liang Tao , David M. Rothwarf
发明人： Mingxian Huang , Lei Wu , Xiaobo Wang , Junquan Xu , Guo Liang Tao , David M. Rothwarf
IPC分类号： C12Q1/68
CPC分类号： C40B40/12 , B01J19/0046 , B01J2219/00457 , B01J2219/00468 , B01J2219/00497 , B01J2219/005 , B01J2219/00502 , B01J2219/0054 , B01J2219/00542 , B01J2219/00547 , B01J2219/00549 , B01J2219/00556 , B01J2219/00576 , B01J2219/00585 , B01J2219/0059 , B01J2219/00592 , B01J2219/00596 , B01J2219/00655 , B01J2219/00659 , B01J2219/00702 , B01J2219/00707 , B01J2219/0072 , B01J2219/00722 , B01J2219/00725 , B01J2219/00729 , B01J2219/00731 , B01J2219/00734 , B01J2219/0074 , B01J2219/00743 , B01L3/5027 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2300/0819 , B01L2400/0415 , B01L2400/043 , B03C5/028 , B82Y5/00 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07K1/047 , C40B40/06 , C40B40/10 , G01N33/54366 , G01N33/54386 , G06K19/06009 , G06K19/06046 , G06K19/06196 , Y10T428/24917
摘要： This invention relates generally to the field of moiety or molecule isolation, detection and manipulation and library synthesis. In particular, the invention provides a microdevice, which microdevice comprises: a) a magnetizable substance; and b) a photorecognizable coding pattern, wherein said microdevice has a preferential axis of magnetization. Systems and methods for isolating, detecting and manipulating moieties and synthesizing libraries using the microdevices are also provided.
摘要翻译：本发明一般涉及部分或分子分离，检测和操作以及文库合成领域。特别地，本发明提供一种微型装置，该微型装置包括：a）可磁化物质; 以及b）可识别的编码图案，其中所述微器件具有优先磁化轴。还提供了用于使用微器件分离，检测和操作部分和合成文库的系统和方法。

10. 发明申请

US20060024732A1 Microdevices having a preferential axis of magnetization and uses thereof 有权
公开(公告)号：US20060024732A1
公开(公告)日：2006-02-02
申请号：US11230411
申请日：2005-09-20
申请人： Mingxian Huang , Lei Wu , Xiaobo Wang , Junquan Xu , Guo Liang Tao , David Rothwarf
发明人： Mingxian Huang , Lei Wu , Xiaobo Wang , Junquan Xu , Guo Liang Tao , David Rothwarf
IPC分类号： C12Q1/68
CPC分类号： C40B40/12 , B01J19/0046 , B01J2219/00457 , B01J2219/00468 , B01J2219/00497 , B01J2219/005 , B01J2219/00502 , B01J2219/0054 , B01J2219/00542 , B01J2219/00547 , B01J2219/00549 , B01J2219/00556 , B01J2219/00576 , B01J2219/00585 , B01J2219/0059 , B01J2219/00592 , B01J2219/00596 , B01J2219/00655 , B01J2219/00659 , B01J2219/00702 , B01J2219/00707 , B01J2219/0072 , B01J2219/00722 , B01J2219/00725 , B01J2219/00729 , B01J2219/00731 , B01J2219/00734 , B01J2219/0074 , B01J2219/00743 , B01L3/5027 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2300/0819 , B01L2400/0415 , B01L2400/043 , B03C5/028 , B82Y5/00 , B82Y10/00 , B82Y30/00 , C07B2200/11 , C07K1/047 , C40B40/06 , C40B40/10 , G01N33/54366 , G01N33/54386 , G06K19/06009 , G06K19/06046 , G06K19/06196 , Y10T428/24917
摘要： This invention relates generally to the field of moiety or molecule isolation, detection and manipulation and library synthesis. In particular, the invention provides a microdevice, which microdevice comprises: a) a magnetizable substance; and b) a photorecognizable coding pattern, wherein said microdevice has a preferential axis of magnetization. Systems and methods for isolating, detecting and manipulating moieties and synthesizing libraries using the microdevices are also provided.

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