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1. 发明专利

GB202015154D0 Intelligent database management platform 未知
公开(公告)号：GB202015154D0
公开(公告)日：2020-11-11
申请号：GB202015154
申请日：2020-09-25
申请人： LI YINGCHUN
摘要： The invention relates to an intelligent database management platform, and the platform comprises: network downloading equipment which is used for downloading the name of a current hot-broadcast film from the Internet, and outputting the name of the current hot-broadcast film as a to-be-processed film name; database search equipment which is used for searching one or more film names associated withthe to-be-processed film from a local film database to serve as one or more corresponding associated film names; and association degree acquisition equipment which is used for acquiring an association level of the associated film name and the to-be-processed film name based on the association degree of the film content of the associated film name and the film content of the to-be-processed film.The intelligent database management platform is reliable in design and convenient to operate. The higher the association level of the associated film name of the current hot-broadcast film is, the higher the VIP level of the user who can watch the associated film corresponding to the associated film name is, so that the graded film watching effect is achieved.

2. 发明专利

GB202013810D0 Recognition system and method based on signal analysis 未知
公开(公告)号：GB202013810D0
公开(公告)日：2020-10-21
申请号：GB202013810
申请日：2020-09-03
申请人： LI YINGCHUN

3. 发明申请

WO2011025964A3 THERAPEUTIC DLL4 BINDING PROTEINS 审中-公开
标题翻译：治疗DLL4结合蛋白
公开(公告)号：WO2011025964A3
公开(公告)日：2011-04-21
申请号：PCT/US2010047006
申请日：2010-08-27
申请人： ABBOTT LAB , BENATUIL LORENZO , BOGHAERT ERWIN R , GU JIJIE , HARRIS MARIA , HICKSON JONATHAN A , HSIEH CHUNG-MING , KUTSKOVA YULIYA , LI YINGCHUN , LIU ZHIHONG , MORGAN-LAPPE SUSAN
发明人： BENATUIL LORENZO , BOGHAERT ERWIN R , GU JIJIE , HARRIS MARIA , HICKSON JONATHAN A , HSIEH CHUNG-MING , KUTSKOVA YULIYA , LI YINGCHUN , LIU ZHIHONG , MORGAN-LAPPE SUSAN
IPC分类号： C07K16/28
CPC分类号： C07K16/22 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K7/06 , C07K7/08 , C07K14/47 , C07K16/18 , C07K2317/21 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： Improved DLL4 binding proteins are described, including antibodies, CDR-grafted antibodies, human antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis, and/or other angiogenesis-dependent diseases such as ocular neovascularization, or angiogenesis-independent diseases characterized by aberrant DLL4 expression or activity such as autoimmune disorders including multiple sclerosis.
摘要翻译：描述了改进的DLL4结合蛋白，包括抗体，CDR-移植抗体，人抗体和DLL4结合片段，以高亲和力结合DLL4的蛋白质，以及中和DLL4活性的DLL4结合蛋白。 DLL4结合蛋白可用于治疗或预防癌症和肿瘤，特别是用于治疗或预防肿瘤血管生成和/或其它血管发生依赖性疾病，例如眼新生血管形成或以异常DLL4表达或活性为特征的血管发生非依赖性疾病，例如自身免疫包括多发性硬化的疾病。

4. 发明申请

WO2011112566A3 BASIGIN BINDING PROTEINS 审中-公开
标题翻译： BASIGIN结合蛋白
公开(公告)号：WO2011112566A3
公开(公告)日：2011-10-27
申请号：PCT/US2011027521
申请日：2011-03-08
申请人： ABBOTT LAB , HSIEH CHUNG-MING , BARLOW EVE H , KINGSBURY GILLIAN ANN , REILLY EDWARD B , MORGAN-LAPPE SUSAN , KARAOGLU HANZATIAN DENISE D , BUCHANAN FRITZ G , LI YINGCHUN
发明人： HSIEH CHUNG-MING , BARLOW EVE H , KINGSBURY GILLIAN ANN , REILLY EDWARD B , MORGAN-LAPPE SUSAN , KARAOGLU HANZATIAN DENISE D , BUCHANAN FRITZ G , LI YINGCHUN
IPC分类号： C07K16/28 , C12P21/08
CPC分类号： C07K16/2803 , A61K2039/505 , C07K2317/24 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/92
摘要： Isolated binding proteins, e.g., antibodies, which bind to Basigin (BSG), e.g., human BSG2, and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies.
摘要翻译：公开了结合Basigin（BSG）（例如人BSG2）的分离的结合蛋白，例如抗体，以及相关的基于抗体的组合物和分子。还公开了包含抗体的药物组合物，以及使用该抗体的治疗和诊断方法。

5. 发明申请

WO2011112566A2 BASIGIN BINDING PROTEINS 审中-公开
标题翻译：基因结合蛋白
公开(公告)号：WO2011112566A2
公开(公告)日：2011-09-15
申请号：PCT/US2011/027521
申请日：2011-03-08
申请人： ABBOTT LABORATORIES , HSIEH, Chung-Ming , BARLOW, Eve H. , KINGSBURY, Gillian Ann , REILLY, Edward B. , MORGAN-LAPPE, Susan , KARAOGLU HANZATIAN, Denise D. , BUCHANAN, Fritz G. , LI, Yingchun
发明人： HSIEH, Chung-Ming , BARLOW, Eve H. , KINGSBURY, Gillian Ann , REILLY, Edward B. , MORGAN-LAPPE, Susan , KARAOGLU HANZATIAN, Denise D. , BUCHANAN, Fritz G. , LI, Yingchun
IPC分类号： A61K39/395 , C07K16/28 , C07K16/46 , C07H21/04 , C12N15/63 , C12N5/16 , C12N5/22 , A61P35/00 , G01N33/574
CPC分类号： C07K16/2803 , A61K2039/505 , C07K2317/24 , C07K2317/565 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/92
摘要： Isolated binding proteins, e.g., antibodies, which bind to Basigin (BSG), e.g., human BSG2, and related antibody-based compositions and molecules are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, as well as therapeutic and diagnostic methods for using the antibodies.
摘要翻译：公开了分离的结合蛋白，例如结合Basigin（BSG）的抗体，例如人BSG2，以及相关的基于抗体的组合物和分子。还公开了包含抗体的药物组合物，以及使用抗体的治疗和诊断方法。

6. 发明申请

WO2011109298A2 THERAPEUTIC DLL4 BINDING PROTEINS 审中-公开
标题翻译：治疗性DLL4结合蛋白
公开(公告)号：WO2011109298A2
公开(公告)日：2011-09-09
申请号：PCT/US2011/026489
申请日：2011-02-28
申请人： ABBOTT LABORATORIES , LI, Yingchun , GU, Jijie, James , MORGAN-LAPPE, Susan , CHEN, Mingjiu , HSIEH, Chung-Ming
发明人： LI, Yingchun , GU, Jijie, James , MORGAN-LAPPE, Susan , CHEN, Mingjiu , HSIEH, Chung-Ming
IPC分类号： A61K49/00 , C07K16/00 , C07K17/00 , C07H21/00 , A61K39/395 , A61P35/00 , A61P43/00 , A61P9/00 , A61P25/28 , A61P17/06 , C12N9/96 , C12N15/63 , C12N1/21 , C12N5/10 , C12N1/15 , C12N1/19 , C12N1/00 , C12P21/00
CPC分类号： C07K16/28 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K2317/24 , C07K2317/73 , C07K2317/76 , C07K2317/92
摘要： DLL4 binding proteins are described herein, including antibodies, CDR-grafted antibodies, humanized antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 and/or VEGF activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis.
摘要翻译：本文描述了DLL4结合蛋白，包括抗体，CDR移植抗体，人源化抗体和其DLL4结合片段，以高亲和力结合DLL4的蛋白，以及中和DLL4的DLL4结合蛋白和/或 VEGF活性。 DLL4结合蛋白可用于治疗或预防癌症和肿瘤，尤其用于治疗或预防肿瘤血管生成。

7. 发明申请

WO2011050262A3 DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF 审中-公开
公开(公告)号：WO2011050262A3
公开(公告)日：2011-06-30
申请号：PCT/US2010053730
申请日：2010-10-22
申请人： ABBOTT LAB , GHAYUR TARIQ , MORGAN-LAPPE SUSAN E , REILLY EDWARD B , KINGSBURY GILLIAN A , PHILLIPS ANDREW , WANG JIEYI , BELL RANDY L , NORVELL SUZANNE M , LI YINGCHUN , LIU JUNJIAN , YING HUA , LIU ZHIHONG
发明人： GHAYUR TARIQ , MORGAN-LAPPE SUSAN E , REILLY EDWARD B , KINGSBURY GILLIAN A , PHILLIPS ANDREW , WANG JIEYI , BELL RANDY L , NORVELL SUZANNE M , LI YINGCHUN , LIU JUNJIAN , YING HUA , LIU ZHIHONG
IPC分类号： C12P21/08
CPC分类号： C07K16/22 , A61K2039/505 , C07K16/28 , C07K16/2863 , C07K16/32 , C07K16/468 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/00
摘要： The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.

8. 发明申请

WO2011050262A2 DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF 审中-公开
公开(公告)号：WO2011050262A2
公开(公告)日：2011-04-28
申请号：PCT/US2010/053730
申请日：2010-10-22
申请人： ABBOTT LABORATORIES , GHAYUR, Tariq , MORGAN-LAPPE, Susan E. , REILLY, Edward B. , KINGSBURY, Gillian A. , PHILLIPS, Andrew , WANG, Jieyi , BELL, Randy L. , NORVELL, Suzanne M. , LI, Yingchun , LIU, Junjian , YING, Hua , LIU, Zhihong
发明人： GHAYUR, Tariq , MORGAN-LAPPE, Susan E. , REILLY, Edward B. , KINGSBURY, Gillian A. , PHILLIPS, Andrew , WANG, Jieyi , BELL, Randy L. , NORVELL, Suzanne M. , LI, Yingchun , LIU, Junjian , YING, Hua , LIU, Zhihong
IPC分类号： A61K51/10 , C07K16/46 , C07K16/32 , C07H21/04 , A61K39/395 , A61P29/00 , A61P21/02 , A61P25/20 , A61P17/06 , A61P19/02 , A61P1/00 , A61P11/00 , A61P1/16 , A61P25/28 , A61P15/00 , A61P3/10 , A61P35/00 , A61P37/06 , A61P9/00 , A61P7/00 , A61P17/00 , C12N15/63 , C12N1/21 , C12N1/11 , C12N5/10 , C12N1/15 , C12N1/19 , C12P21/00
CPC分类号： C07K16/22 , A61K2039/505 , C07K16/28 , C07K16/2863 , C07K16/32 , C07K16/468 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/00 , Y02A50/386 , Y02A50/41 , Y02A50/412 , Y02A50/58
摘要： The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.

9. 发明申请

WO2011025964A2 THERAPEUTIC DLL4 BINDING PROTEINS 审中-公开
标题翻译：治疗性DLL4结合蛋白
公开(公告)号：WO2011025964A2
公开(公告)日：2011-03-03
申请号：PCT/US2010/047006
申请日：2010-08-27
申请人： ABBOTT LABORATORIES , BENATUIL, Lorenzo , BOGHAERT, Erwin, R. , GU, Jijie , HARRIS, Maria , HICKSON, Jonathan, A. , HSIEH, Chung-Ming , KUTSKOVA, Yuliya , LI, Yingchun , LIU, Zhihong , MORGAN-LAPPE, Susan
发明人： BENATUIL, Lorenzo , BOGHAERT, Erwin, R. , GU, Jijie , HARRIS, Maria , HICKSON, Jonathan, A. , HSIEH, Chung-Ming , KUTSKOVA, Yuliya , LI, Yingchun , LIU, Zhihong , MORGAN-LAPPE, Susan
IPC分类号： C07K16/28
CPC分类号： C07K16/22 , A61K39/3955 , A61K45/06 , A61K2039/505 , C07K7/06 , C07K7/08 , C07K14/47 , C07K16/18 , C07K2317/21 , C07K2317/33 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2317/94
摘要： Improved DLL4 binding proteins are described, including antibodies, CDR-grafted antibodies, human antibodies, and DLL4 binding fragments thereof, proteins that bind DLL4 with high affinity, and DLL4 binding proteins that neutralize DLL4 activity. The DLL4 binding proteins are useful for treating or preventing cancers and tumors and especially for treating or preventing tumor angiogenesis, and/or other angiogenesis-dependent diseases such as ocular neovascularization, or angiogenesis-independent diseases characterized by aberrant DLL4 expression or activity such as autoimmune disorders including multiple sclerosis.
摘要翻译：描述了改进的DLL4结合蛋白，包括抗体，CDR移植抗体，人抗体和其DLL4结合片段，以高亲和力结合DLL4的蛋白，以及中和DLL4活性的DLL4结合蛋白。 DLL4结合蛋白可用于治疗或预防癌症和肿瘤，尤其用于治疗或预防肿瘤血管生成和/或其他血管生成依赖性疾病，例如眼新血管形成或以异常DLL4表达或活性为特征的血管生成非依赖性疾病，如自身免疫包括多发性硬化症的疾病。

10. 发明申请

WO2009134776A3 DUAL VARIABLE DOMAIN IMMUNOGLOBULINS AND USES THEREOF 审中-公开
标题翻译：双变量域免疫球蛋白及其用途
公开(公告)号：WO2009134776A3
公开(公告)日：2009-12-23
申请号：PCT/US2009041945
申请日：2009-04-28
申请人： ABBOTT LAB , GHAYUR TARIQ , MORGAN-LAPPE SUSAN E , REILLY EDWARD B , KINGSBURY GILLIAN A , PHILLIPS ANDREW , WANG JIEYI , BELL RANDY L , NORVELL SUZANNE M , LI YINGCHUN , LIU JUNJIAN , YING HUA
发明人： GHAYUR TARIQ , MORGAN-LAPPE SUSAN E , REILLY EDWARD B , KINGSBURY GILLIAN A , PHILLIPS ANDREW , WANG JIEYI , BELL RANDY L , NORVELL SUZANNE M , LI YINGCHUN , LIU JUNJIAN , YING HUA
IPC分类号： A61K39/00
CPC分类号： C07K16/468 , A61K39/39533 , A61K45/06 , A61K2039/505 , C07K16/22 , C07K16/28 , C07K16/2863 , C07K16/32 , C07K2317/31 , C07K2317/565 , C07K2317/64 , C07K2317/71 , C07K2317/73 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/92 , C07K2319/00 , G01N33/6872 , G01N33/74 , G01N2333/515 , G01N2333/705 , Y10S435/81
摘要： The present invention relates to engineered multivalent and multispecific binding proteins, methods of making, and specifically to their uses in the prevention, diagnosis, and/or treatment of disease.
摘要翻译：本发明涉及工程化的多价和多特异性结合蛋白，制备方法，特别涉及它们在疾病的预防，诊断和/或治疗中的用途。

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