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    • 8. 发明授权
    • Sensing switch and detecting method using the same
    • 感应开关及使用其的检测方法
    • US07790440B2
    • 2010-09-07
    • US12272183
    • 2008-11-17
    • Kyu-tae YooJoon-ho KimJun-hong MinSung-ouk JungJi-na NamgoongKui-hyun KimJeo-young ShimKak Namkoong
    • Kyu-tae YooJoon-ho KimJun-hong MinSung-ouk JungJi-na NamgoongKui-hyun KimJeo-young ShimKak Namkoong
    • C12M3/00
    • G01N33/54373
    • Provided are a sensing switch and a sensing method using the same. The sensing switch includes: a substrate; a supporter on the substrate; a sensing plate that is connected to a side of the supporter and is in parallel with the substrate by a predetermined distance; a receptor binding region on an upper surface of an end portion of the sensing plate; an electric or magnetic field generation device that induces deflection of the sensing plate when a receptor bound to the receptor binding region is selectively bound to an electrically or magnetically active ligand; and a pair of switching electrodes that are separated by a predetermined distance and is connected when the sensing plate contacts the substrate due to the deflection of the sensing plate. A target material need not be labelled, a signal processing of a fluorescent or electrical detection signal using an analysis apparatus is not required, and a signal can be directly decoded by confirming whether a current flows through the switch.
    • 提供了一种感测开关和使用该感测开关的感测方法。 感测开关包括:基板; 底物上的支撑物; 感测板,其与所述支撑体的一侧连接并且与所述基板平行预定距离; 在感测板的端部的上表面上的受体结合区域; 当与受体结合区结合的受体选择性地结合到电或磁性活性配体时,引起感测板偏转的电场或磁场产生装置; 以及一对分离预定距离的开关电极,并且当感测板由于感测板的偏转而与基板接触时被连接。 目标材料不需要标注,不需要使用分析装置的荧光或电检测信号的信号处理,并且可以通过确认电流是否流过开关直接解码信号。