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1. 发明申请

WO2010066813A1 STORAGE TANK MONITORING APPARATUS 审中-公开
标题翻译：储存罐监控装置
公开(公告)号：WO2010066813A1
公开(公告)日：2010-06-17
申请号：PCT/EP2009/066771
申请日：2009-12-09
申请人： SENTINEL IMPORT EXPORT (IRELAND) LIMITED , DENBY, Carl , KURT, Reinhardt
发明人： DENBY, Carl , KURT, Reinhardt
IPC分类号： G01F23/26
CPC分类号： G01F23/266 , G01F23/268
摘要： The present invention relates to a storage tank monitoring apparatus and in particular, but not limited to, a storage tank monitoring apparatus for detecting the presence of water in a tank containing a hydrocarbon. The storage tank monitoring apparatus comprises a measurement device for determining a level of a stored substance within in a storage tank, the measurement device being arranged to detect the presence of a second substance in the storage tank; and a processor arranged to generate a signal if the second substance is detected in the storage tank.
摘要翻译：储罐监视装置技术领域本发明涉及一种储罐监视装置，特别涉及包括但不限于用于检测含有碳氢化合物的罐中的水的存在的储罐监视装置。储罐监视装置包括：测量装置，用于确定存储罐内存储物质的含量;测量装置，用于检测存储罐中第二物质的存在; 以及处理器，其布置成在所述储存箱中检测到所述第二物质时产生信号。

2. 发明授权

US08048373B2 Automated high volume slide staining system 有权
标题翻译：自动化大容量载玻片染色系统
公开(公告)号：US08048373B2
公开(公告)日：2011-11-01
申请号：US11876059
申请日：2007-10-22
申请人： Kurt Reinhardt , Charles D. Lemme , Glen Ward , William Richards , Wayne Showalter
发明人： Kurt Reinhardt , Charles D. Lemme , Glen Ward , William Richards , Wayne Showalter
IPC分类号： G01N1/28
CPC分类号： B01L9/52 , B01L2300/0822 , G01N1/312 , G01N1/36 , Y10T436/11 , Y10T436/112499 , Y10T436/25
摘要： An automated slide processing apparatus includes a plurality of work stations arranged in a stack, and a transport/elevator for transporting slides between the various work stations.
摘要翻译：一种自动滑块处理装置，包括以堆叠方式布置的多个工作站，以及用于在各个工作站之间运送滑块的运输/升降机。

3. 发明授权

US07935534B2 Automated molecular pathology apparatus having fixed slide platforms 有权
标题翻译：具有固定滑动平台的自动分子病理装置
公开(公告)号：US07935534B2
公开(公告)日：2011-05-03
申请号：US12818369
申请日：2010-06-18
申请人： Charles Lemme , Devon Campbell , Andrew Ghusson , David Bryant , Kurt Reinhardt , William Richards , Vincent Rizzo , Wayne Showalter
发明人： Charles Lemme , Devon Campbell , Andrew Ghusson , David Bryant , Kurt Reinhardt , William Richards , Vincent Rizzo , Wayne Showalter
IPC分类号： G01N35/00
CPC分类号： G01N1/312 , Y10T436/11 , Y10T436/111666 , Y10T436/112499 , Y10T436/115831 , Y10T436/2575
摘要： Apparatus and methods for automatically staining or treating multiple tissue samples mounted on slides are provided, in which the slides and reagent bottles are held in fixed position, and the reagent, wash and coverslipping solutions brought to the slides. Alternatively, the slides are held in fixed position, while the reagent, wash and coverslipping solutions brought to the slides.
摘要翻译：提供了用于自动染色或处理安装在载玻片上的多个组织样品的装置和方法，其中载玻片和试剂瓶保持在固定位置，并将试剂，洗涤和盖玻片溶液带到载玻片上。或者，幻灯片保持在固定位置，同时将试剂，洗涤和盖玻片溶液带到载玻片上。

4. 发明授权

US07820381B2 Method and apparatus for applying fluids to a biological sample 有权
标题翻译：将流体施加到生物样品的方法和装置
公开(公告)号：US07820381B2
公开(公告)日：2010-10-26
申请号：US11187183
申请日：2005-07-21
申请人： Charles Lemme , Kurt Reinhardt
发明人： Charles Lemme , Kurt Reinhardt
IPC分类号： C12Q1/68 , G01N33/53 , G01N35/00 , C12M1/34 , C12M3/00
CPC分类号： B01L3/0293 , B01L2300/0822 , B01L2400/0406 , B01L2400/0475 , G01N1/2813 , G01N1/30 , G01N1/312 , G01N33/543 , G01N33/54366 , Y10T436/112499
摘要： The invention is directed to a method of contacting a biological sample with a solution, comprising the steps of moving a curved surface wetted with the solution in proximity to the biological sample whereby the distance separating the wetted curved surface and the biological sample is sufficient to form a moving liquid meniscus layer between the two. The invention is also directed to an apparatus for contacting a biological sample suspected of containing a biomarker with a solution, comprising a platform for supporting a microscope slide having a biological sample thereon; a translating cap having a curved lower surface positioned above the platform, the curved lower surface being in proximity to a biological sample when in operation; means for moving the translating cap back and forth over the biological sample; and means for applying and removing liquid to and from the cap.
摘要翻译：本发明涉及一种使生物样品与溶液接触的方法，包括以下步骤：将溶液润湿的曲面移动到生物样品附近，由此分开润湿曲面和生物样品的距离足以形成两者之间移动的液体弯液面层。本发明还涉及一种用于使怀疑含有生物标志物的生物样品与溶液接触的装置，其包括用于支撑其上具有生物样品的显微镜载玻片的平台; 平移盖，其具有位于所述平台上方的弯曲下表面，所述弯曲下表面在操作时靠近生物样品; 用于使翻译盖在生物样品上来回移动的装置; 以及用于施加和去除帽子上的液体的装置。

5. 发明申请

US20100255532A1 Automated Molecular Pathology Apparatus Having Fixed Slide Platforms 有权
标题翻译：具有固定滑动平台的自动分子病理学装置
公开(公告)号：US20100255532A1
公开(公告)日：2010-10-07
申请号：US12818369
申请日：2010-06-18
申请人： Charles Lemme , Devon Campbell , Andrew Ghusson , David Bryant , Kurt Reinhardt , William Richards , Vincent Rizzo , Wayne Showalter
发明人： Charles Lemme , Devon Campbell , Andrew Ghusson , David Bryant , Kurt Reinhardt , William Richards , Vincent Rizzo , Wayne Showalter
IPC分类号： G01N1/28
CPC分类号： G01N1/312 , Y10T436/11 , Y10T436/111666 , Y10T436/112499 , Y10T436/115831 , Y10T436/2575
摘要： Apparatus and methods for automatically staining or treating multiple tissue samples mounted on slides are provided, in which the slides and reagent bottles are held in fixed position, and the reagent, wash and coverslipping solutions brought to the slides. Alternatively, the slides are held in fixed position, while the reagent, wash and coverslipping solutions brought to the slides.
摘要翻译：提供了用于自动染色或处理安装在载玻片上的多个组织样品的装置和方法，其中载玻片和试剂瓶保持在固定位置，并将试剂，洗涤和盖玻片溶液带到载玻片上。或者，幻灯片保持在固定位置，同时将试剂，洗涤和盖玻片溶液带到载玻片上。

6. 发明授权

US06405609B1 System and method of aspirating and dispensing reagent 有权
标题翻译：抽吸和分配试剂的系统和方法
公开(公告)号：US06405609B1
公开(公告)日：2002-06-18
申请号：US09259238
申请日：1999-02-26
申请人： William Richards , Anthony Ford , Vince Rizzo , Darin McDaniel , Kurt Reinhardt
发明人： William Richards , Anthony Ford , Vince Rizzo , Darin McDaniel , Kurt Reinhardt
IPC分类号： B01L302
CPC分类号： G01N35/1002 , G01N1/31 , G01N1/312 , Y10T436/114998 , Y10T436/119163 , Y10T436/25625 , Y10T436/2575
摘要： Apparatus and methods for aspirating and dispensing reagents are provided. Aspirating of reagents is accomplished by a probe, a vial insert and reagent vial according to the present invention wherein a seal is formed between the probe and the vial insert when the probe engages the vial insert. Dispensing of reagents is accomplished by a probe and a probe dispense and wash station according to the present invention wherein a seal is formed between the probe and the vial insert when the probe engages the probe dispense and wash station.
摘要翻译：提供了用于抽吸和分配试剂的装置和方法。通过根据本发明的探针，小瓶插入物和试剂小瓶实现试剂的吸入，其中当探针接合小瓶插入物时，在探针和小瓶插入物之间形成密封。试剂的分配是通过根据本发明的探针和探针分配和洗涤台实现的，其中当探头接合探针分配和洗涤站时，在探针和小瓶插入物之间形成密封。

7. 发明授权

US07727774B2 Method and apparatus for automated coverslipping 有权
标题翻译：自动封盖的方法和装置
公开(公告)号：US07727774B2
公开(公告)日：2010-06-01
申请号：US11838104
申请日：2007-08-13
申请人： Kurt Reinhardt , Anthony Ford , Mirek Holubec
发明人： Kurt Reinhardt , Anthony Ford , Mirek Holubec
IPC分类号： G01N1/10
CPC分类号： B65H3/46 , B65H1/08 , B65H3/0816 , B65H2301/5121 , B65H2301/5133 , G01N1/2813 , G01N2035/00059 , G01N2035/00079 , G02B21/34 , Y10T156/1132 , Y10T156/1195 , Y10T156/1944 , Y10T156/1983 , Y10T156/1994 , Y10T436/11 , Y10T436/112499 , Y10T436/2575
摘要： An apparatus and method for selecting and dispensing coverglasses over specimens on slides for the purpose of viewing specimens through a microscope. The selecting device contains a suctioning mechanism for picking up a coverglass from a stack of coverglasses. It also contains the ability to bend the coverglass to assist in separating the coverglasses. The apparatus further contains a matched barrier to eliminate any coverglasses that may stick to the selected coverglass. The selecting device also contains spring members which aid in the dispensing of the coverglass. After the suctioning mechanism releases the coverglass, the spring members exert a force onto the coverglass to insure that it is released from the selecting device and placed onto the slide. After placement of the coverglass onto the slide, capillary action pushes air bubbles out from underneath the coverglass.
摘要翻译：用于在载玻片上的样品上选择和分配覆盖物以便通过显微镜观察标本的装置和方法。选择装置包括用于从一叠盖子拾起盖玻片的抽吸机构。它还包含弯曲覆盖层以帮助分离覆盖层的能力。该装置还包含匹配的屏障，以消除可能粘附到所选择的覆盖层的任何覆盖物。选择装置还包含有助于分配盖玻片的弹簧构件。在抽吸机构释放盖玻片之后，弹簧构件向盖玻片施加力以确保其从选择装置释放并放置在载玻片上。将玻璃盖放置在玻片上之后，毛细管作用会从盖玻片下方推出气泡。

8. 发明授权

US07271006B2 Method and apparatus for automated coverslipping 有权
标题翻译：自动封盖的方法和装置
公开(公告)号：US07271006B2
公开(公告)日：2007-09-18
申请号：US10424335
申请日：2003-04-25
申请人： Kurt Reinhardt , Anthony Ford , Mirek Holubec
发明人： Kurt Reinhardt , Anthony Ford , Mirek Holubec
IPC分类号： G01N35/00
CPC分类号： B65H3/46 , B65H1/08 , B65H3/0816 , B65H2301/5121 , B65H2301/5133 , G01N1/2813 , G01N2035/00059 , G01N2035/00079 , G02B21/34 , Y10T156/1132 , Y10T156/1195 , Y10T156/1944 , Y10T156/1983 , Y10T156/1994 , Y10T436/11 , Y10T436/112499 , Y10T436/2575
摘要： An apparatus and method for selecting and dispensing coverglasses over specimens on slides for the purpose of viewing specimens through a microscope. The selecting device contains a suctioning mechanism for picking up a coverglass from a stack of coverglasses. It also contains the ability to bend the coverglass to assist in separating the coverglasses. The apparatus further contains a matched barrier to eliminate any coverglasses that may stick to the selected coverglass. The selecting device also contains spring members which aid in the dispensing of the coverglass. After the suctioning mechanism releases the coverglass, the spring members exert a force onto the coverglass to insure that it is released from the selecting device and placed onto the slide. After placement of the coverglass onto the slide, capillary action pushes air bubbles out from underneath the coverglass.
摘要翻译：用于在载玻片上的样品上选择和分配覆盖物以便通过显微镜观察标本的装置和方法。选择装置包括用于从一叠盖子拾起盖玻片的抽吸机构。它还包含弯曲覆盖层以帮助分离覆盖层的能力。该装置还包含匹配的屏障，以消除可能粘附到所选择的覆盖层的任何覆盖物。选择装置还包含有助于分配盖玻片的弹簧构件。在抽吸机构释放盖玻片之后，弹簧构件向盖玻片施加力以确保其从选择装置释放并放置在载玻片上。将玻璃盖放置在玻片上之后，毛细管作用会从盖玻片下方推出气泡。

9. 发明申请

US20070172911A1 Biological sample processing composition and method 审中-公开
标题翻译：生物样品处理组成及方法
公开(公告)号：US20070172911A1
公开(公告)日：2007-07-26
申请号：US11652915
申请日：2007-01-12
申请人： Michael Farrell , Christopher Bieniarz , Kurt Reinhardt , Glen Ward , Jerome Kosmeder , Andrew Ghusson , Eric Walk , Guadalupe Manriquez , Thomas Grogan
发明人： Michael Farrell , Christopher Bieniarz , Kurt Reinhardt , Glen Ward , Jerome Kosmeder , Andrew Ghusson , Eric Walk , Guadalupe Manriquez , Thomas Grogan
IPC分类号： G01N1/30 , G01N33/48
CPC分类号： G01N1/30
摘要： A method and composition are disclosed that are useful for processing biological samples. In one aspect, a biological sample such as a tissue section is treated using a histochemical technique and is contacted with a lipid compound during the process to enhance the definition of cellular and sub-cellular features that are observable in the sample when it is viewed microscopically. In other aspects, a coverslipping composition that includes a lipid compound and a method of coverslipping a sample using the coverslipping composition are disclosed.
摘要翻译：公开了可用于处理生物样品的方法和组合物。在一个方面，使用组织化学技术处理诸如组织切片的生物样品，并且在该过程期间与脂质化合物接触以增强在微观观察时在样品中可观察到的细胞和亚细胞特征的定义。在其它方面，公开了一种包括脂质化合物的覆盖组合物和使用盖玻片组合物覆盖样品的方法。

10. 发明授权

US07005110B2 Method and apparatus for preparing tissue samples for sectioning 有权
公开(公告)号：US07005110B2
公开(公告)日：2006-02-28
申请号：US10029658
申请日：2001-12-20
申请人： Scott Taft , Kurt Reinhardt , Miroslav Holubec , David Bryant
发明人： Scott Taft , Kurt Reinhardt , Miroslav Holubec , David Bryant
IPC分类号： A61B10/00
CPC分类号： G01N1/36 , G01N2001/315 , G01N2001/366 , Y10S436/807 , Y10T436/25 , Y10T436/2525
摘要： The present invention provides a more efficient and faster way to prepare tissue samples for sectioning. More particularly, in accordance with the present invention, a tissue sample is embedded in a porous embedding media in a desired orientation, processed, and sectioned all while being held in the porous embedding media. The post-tissue processing step of manual embedding in paraffin is eliminated from the process.

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