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1. 外观设计

USD673292S1 Multilayer cell culture flask 有权
标题翻译：多层细胞培养瓶
公开(公告)号：USD673292S1
公开(公告)日：2012-12-25
申请号：US29364108
申请日：2010-06-18
申请人： Phillip Clark , Kurt E. Greenizen
设计人： Phillip Clark , Kurt E. Greenizen

2. 发明授权

US09751084B2 Biological culture assembly 有权
公开(公告)号：US09751084B2
公开(公告)日：2017-09-05
申请号：US12589369
申请日：2009-10-22
申请人： Kurt E. Greenizen , Phillip Clark , John J. Doyle
发明人： Kurt E. Greenizen , Phillip Clark , John J. Doyle
IPC分类号： G01N1/30 , C12N5/02 , B01L3/00
CPC分类号： B01L3/5085 , B01L3/50853 , B01L2200/028 , B01L2200/0689 , B01L2300/0822 , B01L2300/0829
摘要： The invention relates to a single use cell culture assembly for use in carrying out bioreactions and growing microorganisms, and tissue and cell cultures. The cell culture assembly is designed to receive an insert having a microscope slide upper surface, and includes a well frame having a plurality of partitioned well compartments, adapted to be positioned on the upper surface of the insert, and includes a liquid-impermeable releasable seal positioned on or within the lower edge of the well frame for maintaining a liquid-impermeable barrier between well compartments.

3. 外观设计

USD662603S1 Magnetic rack 有权
标题翻译：磁架
公开(公告)号：USD662603S1
公开(公告)日：2012-06-26
申请号：US29358973
申请日：2010-04-02
申请人： Kurt E. Greenizen
设计人： Kurt E. Greenizen

4. 发明申请

US20100151511A1 Biological culture assembly 有权
标题翻译：生物文化大会
公开(公告)号：US20100151511A1
公开(公告)日：2010-06-17
申请号：US12589369
申请日：2009-10-22
申请人： Kurt E. Greenizen , Phillip Clark , John J. Doyle
发明人： Kurt E. Greenizen , Phillip Clark , John J. Doyle
IPC分类号： G01N1/30 , C12M1/22 , C12N5/02
CPC分类号： B01L3/5085 , B01L3/50853 , B01L2200/028 , B01L2200/0689 , B01L2300/0822 , B01L2300/0829
摘要： The invention relates to a resealable or a single use cell culture assembly for use in growing, storing and transporting, cell and tissue cultures. The assembly includes a support frame for receiving a base member insert having an upper surface, such as a microscope slide, and a well frame, preferably partitioned into a plurality of well compartments having sidewalls with upper and lower surfaces, upper and lower edges, and upper and lower well openings. The well frame is adapted to be operatively positioned on the upper surface of the base member, and includes a sealing means positioned on or within the lower edge of the well frame. The sealing means is adapted to operatively create a liquid-impermeable releasable seal or barrier when the lower surface of the well frame is positioned on the upper surface of the base member, such that the sealing means is releasably positioned on the upper surface of the base member for maintaining a liquid-impermeable barrier between well compartments. The assembly may include a cover or lid positioned over the upper opening of the well frame. When the assembly is in a closed position, the well frame can be secured to the support frame by a variety of closure means.
摘要翻译：本发明涉及用于生长，储存和运输细胞和组织培养物的可再密封或单次使用的细胞培养组合物。该组件包括用于接收具有上表面的基底构件插入件的支撑框架，例如显微镜载玻片和井眼框架，优选地分隔成具有具有上表面和下表面的侧壁，多个上下边缘的多个井室，以及上下孔开口。井眼框架适于可操作地定位在基部构件的上表面上，并且包括位于井眼框架的下边缘上或内部的密封装置。密封装置适于当井眼框架的下表面位于基部构件的上表面上时可操作地产生液体不可渗透的可释放的密封件或阻挡件，使得密封装置可释放地定位在基座的上表面上用于在井室之间保持液体不可渗透的屏障的构件。组件可以包括位于井架的上开口上方的盖或盖。当组件处于关闭位置时，井架可以通过各种关闭装置固定到支撑框架上。

5. 发明授权

US07588728B2 Multifunctional vacuum manifold 有权
标题翻译：多功能真空歧管
公开(公告)号：US07588728B2
公开(公告)日：2009-09-15
申请号：US10780463
申请日：2004-02-17
申请人： Phillip Clark , Kurt E. Greenizen , John Doyle
发明人： Phillip Clark , Kurt E. Greenizen , John Doyle
IPC分类号： B01L3/02
CPC分类号： B01D61/18 , B01L3/50255 , B01L2200/023 , B01L2200/025 , B01L2200/141 , B01L2300/0829 , B01L2400/049 , Y10T436/25375 , Y10T436/255 , Y10T436/2575
摘要： A laboratory device design particularly for a multiplate format that includes a manifold wherein the position of the plate is not a function of gasket compression or vacuum rate applied. In one embodiment, the device has a modular design, wherein one or more removable inserts, preferably with different functionalities can be positioned between a base component and a collar component. The particular insert(s) chosen depend on the desired sample preparation or assay to be carried out. The insert(s) are stacked and are positioned between the base and collar as a unit, so that the stack within the manifold does not move during evacuation of the vacuum chamber. The consistent position of the insert(s) facilitates using vacuum sample processing with automated liquid handlers.
摘要翻译：一种特别用于包括歧管的多重格式的实验室装置，其中板的位置不是施加垫片压缩或真空率的函数。在一个实施例中，该装置具有模块化设计，其中优选地具有不同功能的一个或多个可移除插入件可以位于基座部件和套环部件之间。所选择的特定插入物取决于要进行的所需样品制备或测定。插入件被堆叠并且被定位在基座和套环之间作为一个单元，使得在抽真空室期间歧管内的叠层不移动。插入件的一致位置有助于使用自动化液体处理器进行真空样品处理。

6. 发明授权

US09272279B2 Immunoassay product and process 有权
标题翻译：免疫测定产品和方法
公开(公告)号：US09272279B2
公开(公告)日：2016-03-01
申请号：US13468258
申请日：2012-05-10
申请人： Chris Scott , Phillip Clark , Kurt E. Greenizen , Ryan A. Amara , Robert Colonna
发明人： Chris Scott , Phillip Clark , Kurt E. Greenizen , Ryan A. Amara , Robert Colonna
IPC分类号： G01N21/75 , B01L3/00 , G01N33/543 , G01N33/569 , B01J20/28
CPC分类号： G01N33/558 , B01J20/28033 , B01J20/28035 , B01J20/2804 , B01L3/5023 , B01L9/52 , B01L2200/025 , B01L2300/0609 , B01L2300/0681 , B01L2300/069 , B01L2300/0809 , B01L2300/12 , B01L2300/126 , B01L2400/0487 , B01L2400/049 , G01N33/54366 , G01N33/56911 , G01N2469/10 , G01N2469/20
摘要： The embodiments disclosed herein are directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.
摘要翻译：本文公开的实施方案涉及用于在印迹膜上进行化合物检测的装置。该装置包括多个层，包括印迹膜下面的多孔支撑层，印迹膜上方的流量分布器，以及任选的流量分配器上的孔，以将液体包含到期望的区域并允许降低这种液体的起始体积。优选地，流动分配器是非结合或低结合的亲水性多孔膜，例如0.22微米的膜，并且支撑层是格栅或烧结的多孔材料。分配器和支撑件保持在一起以在膜周围形成一个信封。在这样做时优选使用铰链，夹子和其它这样的装置。

7. 外观设计

USD679829S1 Multilayer cell culture flask 有权
标题翻译：多层细胞培养瓶
公开(公告)号：USD679829S1
公开(公告)日：2013-04-09
申请号：US29364106
申请日：2010-06-18
申请人： Phillip Clark , Kurt E. Greenizen
设计人： Phillip Clark , Kurt E. Greenizen

8. 发明申请

US20120315189A1 Immunoassay Product And Process 有权
标题翻译：免疫测定产品和方法
公开(公告)号：US20120315189A1
公开(公告)日：2012-12-13
申请号：US13468258
申请日：2012-05-10
申请人： Chris Scott , Phillip Clark , Kurt E. Greenizen , Ryan A. Amara , Robert Colonna
发明人： Chris Scott , Phillip Clark , Kurt E. Greenizen , Ryan A. Amara , Robert Colonna
IPC分类号： G01N33/53
CPC分类号： G01N33/558 , B01J20/28033 , B01J20/28035 , B01J20/2804 , B01L3/5023 , B01L9/52 , B01L2200/025 , B01L2300/0609 , B01L2300/0681 , B01L2300/069 , B01L2300/0809 , B01L2300/12 , B01L2300/126 , B01L2400/0487 , B01L2400/049 , G01N33/54366 , G01N33/56911 , G01N2469/10 , G01N2469/20
摘要： The embodiments disclosed herein are directed to an apparatus useful in conducting detection of compounds on blotting membranes. The device is comprised of several layers including a porous support layer below the blotting membrane(s), a flow distributor above the blotting membrane(s) and optionally a well on the flow distributor to contain the liquid to the desired area and to allow for lower starting volumes of such liquid. Preferably, the flow distributor is a non-binding or low binding hydrophilic porous membrane such as a 0.22 micron membrane and the support layer is a grid or sintered porous material. The distributor and support are held together to form an envelope around the membrane(s). The use of a hinge, clips and other such devices is preferred in doing so.
摘要翻译：本文公开的实施方案涉及用于在印迹膜上进行化合物检测的装置。该装置包括多个层，包括印迹膜下面的多孔支撑层，印迹膜上方的流量分布器，以及任选的流量分配器上的孔，以将液体包含到期望的区域并允许降低这种液体的起始体积。优选地，流动分配器是非结合或低结合的亲水性多孔膜，例如0.22微米的膜，并且支撑层是格栅或烧结的多孔材料。分配器和支撑件保持在一起以在膜周围形成一个信封。在这样做时优选使用铰链，夹子和其它这样的装置。

9. 发明授权

US08007743B2 Multifunctional vacuum manifold 有权
标题翻译：多功能真空歧管
公开(公告)号：US08007743B2
公开(公告)日：2011-08-30
申请号：US12584872
申请日：2009-09-14
申请人： Phil Clark , Kurt E. Greenizen , John Doyle
发明人： Phil Clark , Kurt E. Greenizen , John Doyle
IPC分类号： B01D35/00
CPC分类号： B01D61/18 , B01L3/50255 , B01L2200/023 , B01L2200/025 , B01L2200/141 , B01L2300/0829 , B01L2400/049 , Y10T436/25375 , Y10T436/255 , Y10T436/2575
摘要： A laboratory device design particularly for a multiplate format that includes a manifold wherein the position of the plate is not a function of gasket compression or vacuum rate applied. In one embodiment, the device has a modular design, wherein one or more removable inserts, preferably with different functionalities can be positioned between a base component and a collar component. The particular insert(s) chosen depend on the desired sample preparation or assay to be carried out. The insert(s) are stacked and are positioned between the base and collar as a unit, so that the stack within the manifold does not move during evacuation of the vacuum chamber. The consistent position of the insert(s) facilitates using vacuum sample processing with automated liquid handlers.
摘要翻译：一种特别用于包括歧管的多重格式的实验室装置，其中板的位置不是施加垫片压缩或真空率的函数。在一个实施例中，该装置具有模块化设计，其中优选地具有不同功能的一个或多个可移除插入件可以位于基座部件和套环部件之间。所选择的特定插入物取决于要进行的所需样品制备或测定。插入件被堆叠并且被定位在基座和套环之间作为一个单元，使得在抽真空室期间歧管内的叠层不移动。插入件的一致位置有助于使用自动化液体处理器进行真空样品处理。

10. 发明授权

US07824623B2 Multifunctional vacuum manifold 有权
标题翻译：多功能真空歧管
公开(公告)号：US07824623B2
公开(公告)日：2010-11-02
申请号：US10602426
申请日：2003-06-24
申请人： Phillip Clark , Kurt E. Greenizen , John Doyle
发明人： Phillip Clark , Kurt E. Greenizen , John Doyle
IPC分类号： B01L99/00
CPC分类号： B01D61/18 , B01L3/50255 , B01L2200/023 , B01L2200/025 , B01L2200/141 , B01L2300/0829 , B01L2400/049 , Y10T436/25375 , Y10T436/255 , Y10T436/2575
摘要： A laboratory device design particularly for a multiplate format that includes a manifold wherein the position of the plate is not a function of gasket compression or vacuum rate applied. In one embodiment, the device has a modular design, wherein removable inserts with different functionalities can be positioned between a base component and a collar component. The particular inserts chosen depend on the desired sample preparation or assay to be carried out. The inserts are stacked and are positioned between the base and collar as a unit, so that the stack within the manifold does not move during evacuation of the vacuum chamber. The consistent position of the multiplate facilitates using vacuum sample processing with automated liquid handlers.
摘要翻译：一种特别用于包括歧管的多重格式的实验室装置，其中板的位置不是施加垫片压缩或真空率的函数。在一个实施例中，该装置具有模块化设计，其中具有不同功能的可移除插入件可定位在基座部件和套环部件之间。选择的特定插入物取决于要进行的所需样品制备或测定。插入件被堆叠并且作为一个单元被定位在基座和套环之间，使得在抽真空室期间歧管内的堆叠不移动。多极体的一致位置有助于使用自动化液体处理器进行真空样品处理。

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