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1. 发明专利

JP2012139243A Method of judging inflammatory disease by using single nucleotide polymorphism 有权
标题翻译：使用单核多核苷酸判断炎症疾病的方法
公开(公告)号：JP2012139243A
公开(公告)日：2012-07-26
申请号：JP2012099411
申请日：2012-04-25
申请人： Aritoshi Iida , Institute Of Physical & Chemical Research , Koichi Ozaki , Toshihiro Tanaka , 浩一尾崎 , 独立行政法人理化学研究所 , 敏博田中 , 有俊飯田
发明人： TANAKA TOSHIHIRO , NAKAMURA YUSUKE , ONISHI YOZO , OZAKI KOICHI , IIDA ARITOSHI , HORI SHOJI
IPC分类号： C12Q1/68 , C12N15/09
CPC分类号： C12Q1/6876 , C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： PROBLEM TO BE SOLVED: To identify a novel single nucleotide polymorphism (SNP) associated with the onset and the advancement of inflammatory diseases such as myocardial infarction.SOLUTION: The method for prediction of a morbid risk of myocardial infarction comprises detection of an A/G polymorphism at nucleotide 306 in the nucleotide sequence of exon 25 of a TSBP gene, and onset of the myocardial infarction or high possibility of the onset of the myocardial infarction is judged to be high when the nucleotide 306 is G, and the possibility of the onset of the myocardial infarction is low when the nucleotide is A.
摘要翻译：要解决的问题：确定与炎性疾病如心肌梗死发病和进展相关的新型单核苷酸多态性（SNP）。解决方案：用于预测心肌梗塞病态风险的方法包括检测TSBP基因外显子25的核苷酸序列中核苷酸306处的A / G多态性，以及心肌梗塞发作或高可能性当核苷酸306为G时，心肌梗塞的发作判断为高，当核苷酸为A时，心肌梗死发作的可能性较低。（C）2012，JPO＆INPIT

2. 发明申请

US20080280293A1 Method of Examining Inflammatory Disease and Method of Screening Remedy for Imflammatory Disease 失效
标题翻译：检查炎症疾病的方法和筛查炎症性疾病的方法
公开(公告)号：US20080280293A1
公开(公告)日：2008-11-13
申请号：US11795016
申请日：2006-01-11
申请人： Toshihiro Tanaka , Koichi Ozaki , Aritoshi Iida , Masatsugu Hori , Yusuke Nakamura
发明人： Toshihiro Tanaka , Koichi Ozaki , Aritoshi Iida , Masatsugu Hori , Yusuke Nakamura
IPC分类号： C12Q1/68 , C07H21/04 , G01N33/566
CPC分类号： C12Q1/6883 , C12Q2600/156 , G01N33/566 , G01N33/6893 , G01N2333/705 , G01N2800/32 , G01N2800/324
摘要： A gene polymorphism on a Toll-like receptor gene is analyzed and an inflammatory disease is examined based on the results of the analysis. A remedy for an inflammatory disease is screened by selecting a substance capable of altering the interaction between Toll-like receptor and galectin-2.
摘要翻译：分析Toll样受体基因的基因多态性，并根据分析结果检测炎性疾病。通过选择能够改变Toll样受体和半乳凝素-2的相互作用的物质来筛选炎性疾病的治疗方法。

3. 发明授权

US5945043A Hollow silicone resin particles and method for the preparation thereof 失效
标题翻译：中空硅树脂颗粒及其制备方法
公开(公告)号：US5945043A
公开(公告)日：1999-08-31
申请号：US892489
申请日：1997-07-14
申请人： Mitsuo Hamada , Koichi Ozaki , Toyohiko Yamadera
发明人： Mitsuo Hamada , Koichi Ozaki , Toyohiko Yamadera
IPC分类号： B01J2/04 , B01J13/04 , C08G77/04 , B29B9/12
CPC分类号： B01J13/043 , Y10T428/1372 , Y10T428/1386 , Y10T428/1397 , Y10T428/2982 , Y10T428/2985
摘要： Novel hollow silicone resin particles, having an average particle size of 0.1 to 100 .mu.m are disclosed. The silicone resin particles comprise a skin formed from thermoplastic silicone resin configured in the shape of a hollow capsule. The hollow thermoplastic silicone resin particles are prepared by spraying a dispersion of water and thermoplastic silicone resin dissolved in solvent into hot gas. The hot gas evaporates the solvent and water and at the same time causes solidification of the thermoplastic silicone resin while it is in the spray state, so as to form a plurality of hollow particles therefrom.
摘要翻译：公开了平均粒径为0.1〜100μm的新型中空硅树脂颗粒。有机硅树脂颗粒包括由中空胶囊形状的热塑性硅树脂形成的皮肤。中空热塑性有机硅树脂颗粒通过将溶解在溶剂中的水和热塑性有机硅树脂的分散体喷雾到热气中来制备。热气体蒸发溶剂和水，同时在热塑性硅树脂处于喷射状态时使其固化，从而形成多个中空颗粒。

4. 发明授权

US08825257B2 Autonomous navigation method and autonomous mobile body 有权
标题翻译：自主导航方法和自主移动体
公开(公告)号：US08825257B2
公开(公告)日：2014-09-02
申请号：US13509707
申请日：2010-11-16
申请人： Koichi Ozaki , Rahok Samann
发明人： Koichi Ozaki , Rahok Samann
IPC分类号： G05D1/02
CPC分类号： G05D1/0259
摘要： An autonomous navigation method is a method of causing a mobile body (100) to autonomously navigate while comparing environmental magnetism data obtained in advance by measuring magnetism generated along a navigation path on which the mobile body (100) navigates and measured magnetism detected by actually measuring the magnetism generated along the navigation path when the mobile body (100) navigates along the navigation path. The method includes a step (a) of detecting first measured magnetism and second measured magnetism in different positions on the mobile body (100) and a step (b) of causing the mobile body (100) to autonomously navigate on the basis of the second measured magnetism detected by a magnetism sensor (103), which is not affected by unexpected magnetism (G) not included in the environmental magnetism data, and the environmental magnetism data.
摘要翻译：自主导航方法是一种使移动体（100）自主导航的方法，同时比较通过测量沿着移动体（100）导航的导航路径生成的磁力而预先获得的环境磁数据，并且通过实际测量检测到的测量磁力当移动体（100）沿着导航路径导航时沿导航路径产生的磁力。该方法包括步骤（a），检测移动体（100）上不同位置的第一测量磁力和第二测量磁力;以及步骤（b），使得移动体（100）基于第二测量磁由环境磁数据中不包含不受意外磁力（G）影响的磁传感器（103）检测出的磁测量值和环境磁数据。

5. 发明申请

US20070278317A1 Mini Card Adapter 失效
标题翻译：迷你卡适配器
公开(公告)号：US20070278317A1
公开(公告)日：2007-12-06
申请号：US10598762
申请日：2005-03-10
申请人： Masayoshi Onishi , Yasuaki Wakizaka , Yoshitaka Matsuda , Koichi Ozaki
发明人： Masayoshi Onishi , Yasuaki Wakizaka , Yoshitaka Matsuda , Koichi Ozaki
IPC分类号： G06K21/06
CPC分类号： G06K19/07739 , G06K19/07
摘要： A mini card adapter for removably holding and fixing a mini card in a secure manner is provided. The mini card adapter holds a mini card having the same thickness as the standard card and outline dimensions smaller than those of the standard card. The mini card comprises a reference wall 8 having the same thickness as the standard card and a bulging section 9 formed on the top surface of the reference wall 8. In the reference wall 8, a card pocket 10 for is formed for loading therein the mini card 1. The land section 9 is formed in a region Z corresponding to the emboss section of the standard card, and a part of the land section 9 bulges over the card pocket 10. As a result, an eaves wall 15 for supporting one side of the mini card 1 is formed. The eaves wall 15 has a boss 16 which fits in a hole 3 formed in the mini card 1. A receiving nail 17 for receiving the periphery of the mini card 1 in corporation with the eaves wall 15 is provided on the peripheral lower surface of the card pocket 10.
摘要翻译：提供了一种用于以可靠方式可拆卸地固定和固定微型卡的微型卡适配器。迷你卡适配器容纳具有与标准卡相同厚度的小型卡，并且外形尺寸小于标准卡的尺寸。迷你卡包括具有与标准卡相同厚度的参考壁8和形成在参考壁8的顶表面上的凸起部分9。在参考壁8中，形成有用于在其中装载迷你卡1的卡槽10。陆部9形成在与标准卡的压花部对应的区域Z中，陆部9的一部分在卡袋10上方隆起。结果，形成了用于支撑小型卡1的一侧的檐壁15。檐壁15具有嵌合在形成在小型卡1中的孔3中的凸台16。在卡片袋10的周边下表面上设置有用于接收迷你卡1的外围与檐壁15一起的接收钉17。

6. 发明授权

US06635818B2 Wireless power supply method 失效
公开(公告)号：US06635818B2
公开(公告)日：2003-10-21
申请号：US09935719
申请日：2001-08-24
申请人： Masaaki Ichiki , Koichi Ozaki , Yasushi Morikawa , Makoto Tanaka
发明人： Masaaki Ichiki , Koichi Ozaki , Yasushi Morikawa , Makoto Tanaka
IPC分类号： H01L4108
CPC分类号： H01L41/08 , H02J17/00 , H02J50/30 , H02N1/008 , H02S99/00 , Y10S136/291 , Y10S136/293 , Y10T307/773
摘要： There is provided a wireless-type power supply method that is applied to the case where an object to which energy is to be transmitted is relatively small, such as a micromachine, and that allows high-voltage electrical energy to be transmitted without using a wire. In this method, the optical energy from an light source is converted into high-voltage electrical energy by means of an energy transducer formed of either a piezoelectric element or a photovoltaic element on the above-described object, and the high-voltage electrical energy is supplied to an actuator, whereby the construction of the receiving side of the energy transmission is simplified.

7. 发明授权

US06353033B1 Method and apparatus for cutting high viscosity liquid material 失效
标题翻译：切割高粘度液体材料的方法和设备
公开(公告)号：US06353033B1
公开(公告)日：2002-03-05
申请号：US09628468
申请日：2000-07-31
申请人： Koichi Ozaki , Toru Imaizumi , Koichi Ishida , Toyohiko Yamadera , Mitsuo Hamada
发明人： Koichi Ozaki , Toru Imaizumi , Koichi Ishida , Toyohiko Yamadera , Mitsuo Hamada
IPC分类号： B01F1700
CPC分类号： B26F3/00 , F16K1/02 , F17D1/14 , Y10S516/924
摘要： Method and apparatus for cutting high viscosity liquid material, said apparatus comprising a cylinder divided into upper and lower tanks by a partition with a central discharge opening, a moveable and elevatable liquid supply pipe with a distal end positioned opposite the discharge opening, the liquid supply pipe being mounted so that it can be raised until its distal end contacts the partition around the discharge opening, and then lowered until there is no contact, means for raising and lowering the liquid supply pipe, the upper tank having peripheral injection ports for injecting a low viscosity liquid into the upper tank, means for feeding high viscosity liquid material into the lower tank and flowing it into the upper tank, means for feeding low viscosity liquid into the liquid supply pipe and for feeding low viscosity liquid into the peripheral injection ports, the high viscosity liquid material flowing from the lower tank into the upper tank when the liquid supply pipe is lowered, the high viscosity liquid material being pushed upwardly into the upper tank by the low viscosity liquid when the liquid supply pipe is raised, whereby the high viscosity liquid material being pushed upwardly in the upper tank is cut into blocks by the low viscosity liquid being injected into the upper tank.
摘要翻译：用于切割高粘度液体材料的方法和装置，所述装置包括通过具有中心排出口的分隔件分成上部和下部罐的圆筒，具有与排出口相对的远端的可移动和可升高的液体供应管，液体供应管被安装成可以升高直到其远端接触排放口周围的隔板，然后降低直到不接触，用于升高和降低液体供给管的装置，上部罐具有用于注入的周边注入口低粘度液体进入上部罐，用于将高粘度液体材料进入下部罐并将其流入上部罐的装置，用于将低粘度液体供给到液体供给管中并将低粘度液体供给到外部喷射口中的装置，当液体供应管较低时，高粘度液体材料从下槽流入上罐 d，当液体供应管升高时，高粘度液体材料被低粘度液体向上推入上罐，由此通过低粘度液体将在上槽中向上推的高粘度液体材料切成块注入上水箱。

8. 发明授权

US08048625B2 Method of examining inflammatory disease and method of screening remedy for inflammatory disease 失效
标题翻译：检查炎性疾病的方法和筛查炎症性疾病的治疗方法
公开(公告)号：US08048625B2
公开(公告)日：2011-11-01
申请号：US11793716
申请日：2005-12-22
申请人： Toshihiro Tanaka , Koichi Ozaki , Aritoshi Iida , Masatsugu Hori , Yozo Ohnishi , Yusuke Nakamura
发明人： Toshihiro Tanaka , Koichi Ozaki , Aritoshi Iida , Masatsugu Hori , Yozo Ohnishi , Yusuke Nakamura
IPC分类号： C07H21/04 , C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/136 , C12Q2600/156
摘要： A single nucleotide polymorphism occurring on a leptin receptor gene is analyzed and an inflammatory disease is examined on the basis of the analytical data. Further, a substance capable of changing the interaction between the leptin receptor and galectin-2 is selected to thereby screen a remedy for an inflammatory disease.
摘要翻译：分析在瘦素受体基因上发生的单核苷酸多态性，并根据分析数据检查炎性疾病。此外，选择能够改变瘦素受体和半乳凝素-2之间的相互作用的物质，从而筛选炎性疾病的治疗方法。

9. 发明授权

US08026063B2 Method of examining inflammatory disease and method of screening remedy for imflammatory disease 失效
标题翻译：检查炎性疾病的方法和筛查炎症性疾病的治疗方法
公开(公告)号：US08026063B2
公开(公告)日：2011-09-27
申请号：US11795016
申请日：2006-01-11
申请人： Toshihiro Tanaka , Koichi Ozaki , Aritoshi Iida , Masatsugu Hori , Yusuke Nakamura
发明人： Toshihiro Tanaka , Koichi Ozaki , Aritoshi Iida , Masatsugu Hori , Yusuke Nakamura
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6883 , C12Q2600/156 , G01N33/566 , G01N33/6893 , G01N2333/705 , G01N2800/32 , G01N2800/324
摘要： A gene polymorphism on a Toll-like receptor gene is analyzed and an inflammatory disease is examined based on the results of the analysis. A remedy for an inflammatory disease is screened by selecting a substance capable of altering the interaction between Toll-like receptor and galectin-2.
摘要翻译：分析Toll样受体基因的基因多态性，并根据分析结果检测炎性疾病。通过选择能够改变Toll样受体和半乳凝素-2的相互作用的物质来筛选炎性疾病的治疗方法。

10. 发明申请

US20110097711A1 METHOD OF JUDGING INFLAMMATORY DISEASE BY USING SINGLE NUCLEOTDIE POLYMORPHISM 失效
标题翻译：使用单核细胞多态性判断炎症疾病的方法
公开(公告)号：US20110097711A1
公开(公告)日：2011-04-28
申请号：US11813450
申请日：2006-01-06
申请人： Toshihiro Tanaka , Yusuke Nakamura , Yozo Ohnishi , Koichi Ozaki , Aritoshi Iida , Masatsugu Hori
发明人： Toshihiro Tanaka , Yusuke Nakamura , Yozo Ohnishi , Koichi Ozaki , Aritoshi Iida , Masatsugu Hori
IPC分类号： C12Q1/68 , C07H21/00
CPC分类号： C12Q1/6876 , C12Q1/6883 , C12Q2600/136 , C12Q2600/156 , C12Q2600/158 , C12Q2600/172
摘要： An object of the present invention is to identify a novel single nucleotide polymorphism (SNP) associated with the onset and the advancement of inflammatory diseases such as myocardial infarction. The present invention provides a method for judging an inflammatory disease which comprises detecting at least 1 type of genetic polymorphism existing in at least one gene selected from the group consisting of the LBP-32 gene, the TSBP gene, and the WAP gene.
摘要翻译：本发明的目的是鉴定与炎性疾病如心肌梗塞的发病和进展相关的新型单核苷酸多态性（SNP）。本发明提供了一种判断炎症性疾病的方法，该方法包括检测存在于选自LBP-32基因，TSBP基因和WAP基因的至少一种基因中的至少1种遗传多态性。

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