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1. 发明申请

US20070181573A1 Protective container 审中-公开
标题翻译：保护容器
公开(公告)号：US20070181573A1
公开(公告)日：2007-08-09
申请号：US11349626
申请日：2006-02-08
申请人： Kevin Dawson , Peter Hess , Mathias Weinzen
发明人： Kevin Dawson , Peter Hess , Mathias Weinzen
IPC分类号： B65D6/28
CPC分类号： B65D11/02 , A45C11/00 , B29C49/00 , B29K2023/12 , B29K2027/06 , B29L2031/712
摘要： A container comprising a first tubular body defining a fastening structure and a seam that extends across an end wall, and at least one depressed channel formed in the end wall. The seam is located in the depressed channel so as to separate the seam from the contents of the container. In an embodiment, there is a second tubular body secured to the first tubular body by a fastening structure that cooperates with the fastening structure of the first tubular body. The second tubular body also has a seam that extends across a wall that is located in a depressed channel so as to separate the seam from the contents of the container.
摘要翻译：一种容器，包括限定紧固结构的第一管状体和延伸穿过端壁的接缝，以及形成在端壁中的至少一个凹陷通道。接缝位于凹陷的通道中，以将接缝与容器的内容物分开。在一个实施例中，存在通过与第一管状体的紧固结构配合的紧固结构固定到第一管状体的第二管状体。第二管状体还具有延伸穿过位于凹陷通道中的壁的接缝，以便将接缝与容器的内容物分开。

2. 发明申请

US20070184511A1 Method for Diagnosing a Person Having Sjogren's Syndrome 审中-公开
标题翻译：诊断患有干燥综合征的人的方法
公开(公告)号：US20070184511A1
公开(公告)日：2007-08-09
申请号：US11561878
申请日：2006-11-20
申请人： Kevin Dawson , Wasyl Malyj , William Haddon , Daniel Tuse , Earl White , Driss Zoukhri , Ian Rawe
发明人： Kevin Dawson , Wasyl Malyj , William Haddon , Daniel Tuse , Earl White , Driss Zoukhri , Ian Rawe
IPC分类号： C12Q1/37 , G06F19/00
CPC分类号： G01N33/6848 , G16H10/20 , G16H50/70
摘要： Described is a method for diagnosing a person having or being at risk of developing Sjögren's Syndrome and excluding patients with symptoms similar to Sjögren's Syndrome but with a different etiology, comprising the following steps: providing a sample of a body fluid or tissue from said person, said sample containing a mixture of unknown proteins, protein fragments or peptides; analyzing said samples with mass spectrometry to generate a m/z (mass to charge ratio) spectrogram for each sample; comparing whether the patient's sample contains m/z values that are characteristic of a Sjögren's Syndrome reference database derived from the analysis and cataloguing of multiple patient spectrograms; and determining whether said patient either has or does not have Sjögren's Syndrome on the basis of this comparative analysis.
摘要翻译：描述了一种用于诊断患有或有发展Sjögren综合征风险的人的方法，并排除具有与Sjögren综合征相似但具有不同病因的症状的患者，其包括以下步骤：从所述人提供体液或组织的样品，所述样品含有未知蛋白质，蛋白质片段或肽的混合物; 通过质谱分析所述样品以产生每个样品的m / z（质荷比）谱图; 比较患者样本是否包含源自多个患者谱图分析和编目的Sjögren综合征参考数据库特征的m / z值; 并且基于该比较分析确定所述患者是否具有或不具有Sjögren综合征。

3. 发明申请

US20190086425A1 Diagnostic for sjorgen's syndrome based on a biomarker 审中-公开
公开(公告)号：US20190086425A1
公开(公告)日：2019-03-21
申请号：US15732255
申请日：2017-10-13
申请人： Earl Lee White , Kevin Dawson
发明人： Earl Lee White , Kevin Dawson
IPC分类号： G01N33/68 , C07K14/47 , C07K16/18
摘要： A method, assay, peptide and antibody that forms an antibody-antigen conjugate with the peptide comprising the amino acid sequence:GPPPPPGKPQGPPPQGGNKPQGPPPPGKPQGPPAQGGSKSQSARAPPGKPQGPPQQE GNNPQGPPPPAGGNPQQPQAPP or an amino acid sequence that is at least 75% identical to said sequence, and the formation of an antigen-antibody conjugate is a positive indictor for Sjögren's Syndrome.

4. 发明申请

US20050160080A1 System and method of context-specific searching in an electronic database 审中-公开
标题翻译：电子数据库中上下文特定搜索的系统和方法
公开(公告)号：US20050160080A1
公开(公告)日：2005-07-21
申请号：US10759784
申请日：2004-01-16
申请人： Kevin Dawson
发明人： Kevin Dawson
IPC分类号： G06F7/00 , G06F17/30
CPC分类号： G06F16/335 , G06F2216/11
摘要： A user can search a database within a “context” that can be invoked with a context term, or name. The context is pre-defined by a human expert, or curator. The context definition is used in conjunction with a search term provided by the user to efficiently obtain search results that can otherwise be difficult to attain, such as detecting characteristics of data over multiple documents or other database items to infer trends, phenomena, characteristics, or other properties of the data. A context can be a category of items where each item has a distinct name. Search results are presented using the context based on the number of co-occurrences of the search term and terms relating to the context. In a preferred embodiment, the search results are presented as a list with documents having higher co-occurrences ordered at the top of the list. Context definition sets can be created and updated as an ongoing service to a subscriber. Several processing configurations are presented.
摘要翻译：用户可以搜索可以使用上下文术语或名称调用的“上下文”内的数据库。上下文由人类专家或策展人预先定义。上下文定义与用户提供的搜索项结合使用，以有效地获得可能难以实现的搜索结果，诸如检测多个文档或其他数据库项目上的数据的特征以推断趋势，现象，特征或数据的其他属性。上下文可以是每个项目具有不同名称的项目类别。搜索结果使用基于搜索词的共同出现次数和与上下文相关的术语的上下文来呈现。在优选实施例中，搜索结果被呈现为具有在列表顶部排列的具有较高共同事件的文档的列表。可以创建上下文定义集并将其更新为用户正在进行的服务。介绍几种处理方案。

5. 发明申请

US20110301091A1 COMPOSITIONS AND METHODS FOR REDUCING THE SIGNS OF AGING OF THE SKIN 审中-公开
标题翻译：用于减少皮肤老化迹象的组合物和方法
公开(公告)号：US20110301091A1
公开(公告)日：2011-12-08
申请号：US13127249
申请日：2009-11-03
申请人： Giammaria Giuliani , Raymond Rodriguez , Kevin Dawson
发明人： Giammaria Giuliani , Raymond Rodriguez , Kevin Dawson
IPC分类号： A61K38/16 , A61Q19/08 , A61P3/02 , A61P17/00 , A61K38/02 , C12Q1/02
CPC分类号： A61K38/168
摘要： Compositions and methods used to reduce the visible signs of aging of the skin by recalibrating the expression of genes, genetic networks, and cellular pathways in the human skin, particularly using combinations of natural compounds that produce synergistic effects on the expression of genes and genetic networks.
摘要翻译：用于通过重新校准人皮肤中基因，遗传网络和细胞途径的表达，特别是使用对基因和遗传网络的表达产生协同作用的天然化合物的组合来减少皮肤老化的可见迹象的组合物和方法。

6. 发明申请

US20070249000A1 METHOD FOR DIAGNOSING A PERSON HAVING B-CELL PATHOLOGIES 审中-公开
标题翻译：用于诊断患有B细胞病毒的人的方法
公开(公告)号：US20070249000A1
公开(公告)日：2007-10-25
申请号：US11740272
申请日：2007-04-25
申请人： Daniel Tuse , Kevin Dawson , William Haddon , Earl White , Wasyl Malyj
发明人： Daniel Tuse , Kevin Dawson , William Haddon , Earl White , Wasyl Malyj
IPC分类号： G01N33/574 , G01N33/50
CPC分类号： G01N33/57407
摘要： Described is a method for diagnosing a person having or being at risk of developing certain B-cell pathologies, including Sjögren's Syndrome and non-Hodgkin's lymphoma, and excluding patients with symptoms similar to Sjögren's Syndrome but with a different etiology, comprising the following steps: providing a sample of a body fluid or tissue from said person, said sample containing a mixture of unknown proteins, protein fragments or peptides; analyzing said samples with mass spectrometry to generate a m/z (mass to charge ratio) spectrogram for each sample; comparing whether the patient's sample contains m/z values that are characteristic of a Sjögren's Syndrome reference database derived from the analysis and cataloguing of multiple patient spectrograms; and determining whether said patient either has or does not have Sjögren's Syndrome on the basis of this comparative analysis.
摘要翻译：描述了一种用于诊断具有或具有发展某些B细胞病变的风险的人的方法，包括Sjögren综合征和非霍奇金淋巴瘤，并且排除具有与Sjögren综合征相似但具有不同病因的患者，包括以下步骤：提供来自所述人的体液或组织的样品，所述样品含有未知蛋白质，蛋白质片段或肽的混合物; 通过质谱分析所述样品以产生每个样品的m / z（质荷比）谱图; 比较患者样本是否包含源自多个患者谱图分析和编目的Sjögren综合征参考数据库特征的m / z值; 并且基于该比较分析确定所述患者是否具有或不具有Sjögren综合征。

7. 发明申请

US20050160082A1 System and method of context-specific searching in an electronic database 审中-公开
公开(公告)号：US20050160082A1
公开(公告)日：2005-07-21
申请号：US10768034
申请日：2004-01-30
申请人： Kevin Dawson
发明人： Kevin Dawson
IPC分类号： G06F7/00 , G06F17/30
CPC分类号： G06F16/335 , G06F2216/11
摘要： A user can search a database within a “context” that can be invoked with a context term, or name. The context is pre-defined by a human expert, or curator. The context definition is used in conjunction with a search term provided by the user to efficiently obtain search results that can otherwise be difficult to attain, such as detecting characteristics of data over multiple documents or other database items to infer trends, phenomena, characteristics, or other properties of the data. A context can be a category of items where each item has a distinct name. Search results are presented using the context based on the number of co-occurrences of the search term and terms relating to the context. In a preferred embodiment, the search results are presented as a list with documents having higher co-occurrences ordered at the top of the list. Context definition sets can be created and updated as an ongoing service to a subscriber. Several processing configurations are presented.

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