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    • 5. 发明申请
    • Sulfonate compound and fluorescent probe using the same
    • 磺酸盐化合物和使用其的荧光探针
    • US20060105410A1
    • 2006-05-18
    • US11328995
    • 2006-01-10
    • Hatsuo MaedaKazumasa HirataKazuhisa Miyamoto
    • Hatsuo MaedaKazumasa HirataKazuhisa Miyamoto
    • G01N33/537C07D265/34C07D311/88
    • G01N33/581C07D311/82C12Q1/26C12Q1/30G01N33/02
    • The present invention provides a sulfonate compound including a structure represented by a general formula (I) below. In the formula (I), an atomic group A-O is an atomic group that forms a fluorescent compound upon cleavage of a covalent bond with a sulfonyl group. There may be one or plural atomic groups B—SO3— bound to an atomic group A. B is a ring substituted by one or plural electron-withdrawing groups. The electron-withdrawing group includes at least one selected from the group consisting of halogens, a carboxyl group, a carbamoyl group, a straight or branched alkylcarbamoyl group, a straight or branched alkanoyl group, a straight or branched alkoxycarbonyl group, a straight or branched alkyl halide group, and —NR3+ group (the three Rs each denote a hydrogen atom or a straight or branched alkyl group and may be the same or different). When there are plural Bs, the Bs may be the same or different.
    • 本发明提供了包含由下述通式(I)表示的结构的磺酸盐化合物。 在式(I)中,原子团A-O是在与磺酰基共价键断裂时形成荧光化合物的原子团。 可以有一个或多个与原子团A结合的原子团B-SO 3 - .B是被一个或多个吸电子基取代的环。 吸电子基团包括选自卤素,羧基,氨基甲酰基,直链或支链烷基氨基甲酰基,直链或支链烷酰基,直链或支链烷氧基羰基,直链或支链 烷基卤基和-NR 3 SO 2 +基团(三个R 3各自表示氢原子或直链或支链烷基,可以相同或不同)。 当有多个B时,B可以相同或不同。