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1. 发明授权

US4640292A Extending sample volume in pulsed Doppler systems 失效
标题翻译：在脉冲多普勒系统中扩展样本体积
公开(公告)号：US4640292A
公开(公告)日：1987-02-03
申请号：US827670
申请日：1986-02-10
申请人： Alexander Tykulsky , Karl E. Thiele , Leslie I. Halberg
发明人： Alexander Tykulsky , Karl E. Thiele , Leslie I. Halberg
IPC分类号： A61B8/06 , G01P5/24 , A61B10/00
CPC分类号： A61B8/06 , G01P5/244
摘要： The sampling volume of a pulsed Doppler system is increased to a length greater than that corresponding to one pulse by sampling the reflections of each launched pulse a plurality of successive times and accumulating the samples.
摘要翻译：脉冲多普勒系统的采样体积通过对多个连续次数的每次发射脉冲的反射进行采样而增加到比对应于一个脉冲的长度的长度，并且累积样本。

2. 发明授权

US06517491B1 Transducer with spatial sensor 失效
标题翻译：传感器与空间传感器
公开(公告)号：US06517491B1
公开(公告)日：2003-02-11
申请号：US09702328
申请日：2000-10-31
申请人： Karl E Thiele , Showna Hsu-Hwa Chang
发明人： Karl E Thiele , Showna Hsu-Hwa Chang
IPC分类号： A61B814
CPC分类号： A61B8/14 , A61B8/4254
摘要： An ultrasound system comprising an ultrasound unit and a transducer. The transducer including a transducer housing integrating at least one element integrated and a first spatial locator unit. The ultrasound unit includes an imaging unit that receives an echo signal from the at least one element of the transducer and outputs echo data. A second spatial locator unit, in communication with the first spatial locator unit, is integrated with the ultrasound unit. The second spatial locator unit enables the determination of a location of the transducer housing.
摘要翻译：一种包括超声单元和换能器的超声系统。换能器包括集成至少一个元件集成的第一空间定位器单元的换能器壳体。超声单元包括成像单元，其接收来自换能器的至少一个元件的回波信号并输出回波数据。与第一空间定位器单元通信的第二空间定位器单元与超声单元集成。第二空间定位器单元能够确定换能器壳体的位置。

3. 发明授权

US06224557B1 Ultrasonic method using adaptive clutter filter to remove tissue wall motion 失效
标题翻译：超声波法采用自适应杂波滤波器去除组织壁运动
公开(公告)号：US06224557B1
公开(公告)日：2001-05-01
申请号：US09497579
申请日：2000-02-03
申请人： J Mark Ziel , Karl E Thiele
发明人： J Mark Ziel , Karl E Thiele
IPC分类号： A61B800
CPC分类号： G01S15/8981 , A61B8/06 , A61B8/13 , G01S7/52038
摘要： The method of the invention controls an ultrasound system that implements a clutter filter, to derive parameters such as blood flow velocity, echo power and/or echo amplitude data from an anatomical region of interest (ROI) and into which a contrast agent has been introduced. The method initially transmits an ensemble of N ultrasound beams along a common azimuth and elevation into the ROI to cause destruction of the contrast agent lying along the azimuth. Estimated wall motion velocity data is then derived for the tissue wall region through use of selected echo signal data derived from a subset of the N ultrasound beams of the ensemble, the subset excluding echo signal data from a first M of the N ultrasound beams or any subset of the N ultrasound beams. The clutter filter is then adjusted to attenuate selected echo signal data returned from the ROI that exhibits the wall motion velocity data. The wall motion data derived from the N ultrasound beams or a subset thereof is processed by the adjusted clutter filter to derive echo data that is better indicative of echo signal returns from the contrast agent or blood flow and is less indicative of wall motion effects.
摘要翻译：本发明的方法控制实现杂波滤波器的超声系统，从感兴趣的解剖区域（ROI）导出诸如血流速度，回波功率和/或回波幅度数据的参数，并且引入了造影剂。该方法首先将N个超声波束沿着共同的方位角和高度传播到ROI中，以引起沿着方位角的造影剂的破坏。然后通过使用从该组合的N个超声波束的子集导出的所选择的回波信号数据，针对组织壁区域导出估计的壁运动速度数据，该子集不包括来自N个超声波束的第一个M的任何 N个超声波束的子集。然后调整杂波滤波器以衰减从呈现壁运动速度数据的ROI返回的所选择的回波信号数据。从N个超声波束或其子集导出的壁面运动数据由调整的杂波滤波器处理，以导出更好地指示来自造影剂或血流的回波信号返回的回波数据，并且较少表示壁运动效应。

4. 发明授权

US5669386A Ultrasonic flow measurement system employing cross-correlation of baseband reflection data 失效
标题翻译：超声波流量测量系统采用基带反射数据的互相关
公开(公告)号：US5669386A
公开(公告)日：1997-09-23
申请号：US692789
申请日：1996-07-31
申请人： Karl E. Thiele , Richard A. Hager , David W. Clark , Jerome F. Witt
发明人： Karl E. Thiele , Richard A. Hager , David W. Clark , Jerome F. Witt
IPC分类号： A61B8/06 , G01P5/22 , G01P5/24 , G01S7/531 , G01S15/89 , A61B8/00 , A61B8/12
CPC分类号： G01S15/8979 , G01P5/22 , G01P5/244 , G01S7/52044
摘要： An ultrasound flow measurement system converts each of plural groups of reflection sample values from scatterers, into baseband complex data values and enables a velocity determination from just two lag samples. A cross correlation function derives a first cross-correlation value between a first set of complex data values that are derived at a first common sample time, during succeeding transmit events, and a second set of complex data values that are derived at a second common sample time, during succeeding transmit events. A second cross-correlation function derives a second cross-correlation value between the first set of complex data values and a third set of complex data values that are derived at the common second sample time. A local oscillator synchronizes both the baseband conversion and cross-correlation operation, and exhibits a rate of change of phase per sample time. A processor relates the rate of change of phase of the local oscillation signal, the first cross-correlation value and the second cross-correlation value to derive the velocity of the ultrasound scatterers. In particular, the first and second cross-correlation values enable establishment of a linear function defining the phase of the cross-correlation function of the complex data values. The rate of change of phase of the local oscillation signal enables establishment of a further linear function. The intersection of the two linear functions identifies the time at which a maxima occurs of the cross-correlation function, thereby enabling derivation of the velocity of the scatterers.
摘要翻译：超声波流量测量系统将来自散射体的多组反射样本值中的每一个转换为基带复合数据值，并且仅使用两个滞后样本的速度确定。互相关函数导出在第一公共采样时间，后续发送事件期间导出的第一组复数据值和在第二公共样本中导出的第二组复数据值之间的第一互相关值时间，在成功的传输事件。第二互相关函数导出第一组复数据值之间的第二互相关值和在公共第二采样时间导出的第三组复数数据值。本地振荡器同步基带转换和互相关操作，并且显示每个采样时间的相位变化率。处理器涉及本地振荡信号的相位变化率，第一互相关值和第二互相关值，以导出超声波散射体的速度。特别地，第一和第二互相关值使得能够建立定义复数数据值的互相关函数的相位的线性函数。本地振荡信号的相位变化率使得能够建立进一步的线性函数。两个线性函数的交点识别互相关函数发生最大值的时间，从而能够推导出散射体的速度。

5. 发明申请

US20130261458A1 ANALYSIS OF MITRAL REGURGITATION FROM SLIT ORIFICES BY ULTRASONIC IMAGING 审中-公开
标题翻译：通过超声波成像从狭缝分析中分析麻醉药物
公开(公告)号：US20130261458A1
公开(公告)日：2013-10-03
申请号：US13991551
申请日：2011-12-15
申请人： Qifeng Wei , Karl E. Thiele , Ajit P. Yoganathan , Choon-Hwai Yap
发明人： Qifeng Wei , Karl E. Thiele , Ajit P. Yoganathan , Choon-Hwai Yap
IPC分类号： A61B8/06 , A61B8/00 , A61B8/14 , A61B8/08
CPC分类号： A61B8/06 , A61B8/145 , A61B8/4444 , A61B8/4488 , A61B8/463 , A61B8/483 , A61B8/488 , A61B8/5207 , A61B8/5223
摘要： An ultrasonic diagnostic imaging system is described which quantifies regurgitant flow through a plurality of pinhole leaks or a slit leak of a mitral valve. A plurality of orifice locations of a leaking valve are identified and Doppler values obtained from a flow velocity field proximal each orifice. The Doppler values of each flow velocity field vectorially relating to the orifice location are processed to produce a measure of flow through the orifice. The flow measurements for a plurality of such orifices are summed to produce a quantified measure of regurgitant flow through a plurality of pinhole leaks or along a slit leak.
摘要翻译：描述了超声波诊断成像系统，其定量通过多个针孔泄漏或二尖瓣的狭缝泄漏的反流量。识别泄漏阀的多个孔位置，并从每个孔附近的流速场获得多普勒值。对与孔口位置进行矢量相关的每个流速场的多普勒值进行处理，以产生通过孔口的流量的量度。将多个这样的孔的流量测量相加以产生通过多个针孔泄漏或沿着狭缝泄漏的回流量的量化测量。

6. 发明授权

US08477135B2 Method and apparatus for volume rendering using depth weighted colorization 有权
标题翻译：使用深度加权着色进行体绘制的方法和装置
公开(公告)号：US08477135B2
公开(公告)日：2013-07-02
申请号：US12302946
申请日：2007-05-29
申请人： Karl E. Thiele
发明人： Karl E. Thiele
IPC分类号： G06T15/50 , G06T15/60 , G06T17/00 , G09G5/02
CPC分类号： G06T15/06 , G06T15/08 , G06T15/40
摘要： A method of volume rendering includes obtaining data representative of a first composited plane of one or more anatomical structures and calculating data of a second composited plane as a function of a first composited plane. The data of the second composited plane is indicative of a measure of depth of the one or more anatomical structures along respective ray cast lines. The method also includes determining depth weighted color values between two different colorization palettes as a function of the measure of depths of the second composited plane. The determined depth weighted color values are applied to the first composited plane for producing a volume rendering image with depth weighted colorization.
摘要翻译：体绘制的方法包括获得代表一个或多个解剖结构的第一合成平面的数据，并且计算作为第一合成平面的函数的第二合成平面的数据。第二合成平面的数据指示沿着相应的射线投射线的一个或多个解剖结构的深度的度量。该方法还包括确定两个不同着色调色板之间的深度加权色值作为第二合成平面深度测量的函数。将确定的深度加权颜色值应用于第一合成平面，以产生具有深度加权着色的体绘制图像。

7. 发明申请

US20100004540A1 DUAL PATH PROCESSING FOR OPTIMAL SPECKLE TRACKING 审中-公开
标题翻译：用于最佳追踪的双路加工
公开(公告)号：US20100004540A1
公开(公告)日：2010-01-07
申请号：US12447969
申请日：2007-11-02
申请人： Karl E. Thiele
发明人： Karl E. Thiele
IPC分类号： A61B8/00
CPC分类号： A61B8/08 , G01S7/52026 , G01S7/52071 , G01S7/52077 , G01S15/8979 , G01S15/8995
摘要： This invention relates generally to an improved system and method that combines enhancing and mitigating techniques for speckle tracking, for obtaining a series of images of the movement of a target, such as tissue, over time. The method comprises steps of transmitting sound waves into the human body and outputting echoes of these sound waves; receiving and beamforming the echoes to produce scan line data; processing scan line data to display anatomical information using a method which reduces speckle; processing scan line data using a method or procedure which does not reduce speckle, and during one scan sequence, simultaneously acquiring the two scan line data, that data processed reducing speckle and that data processed without reducing speckle.
摘要翻译：本发明一般涉及一种改进的系统和方法，该系统和方法结合了用于散斑跟踪的增强和减轻技术，用于随时间获得目标（例如组织）的运动的一系列图像。该方法包括以下步骤：将声波传输到人体内并输出这些声波的回波; 接收和波束成形回波以产生扫描线数据; 使用减少斑点的方法处理扫描线数据以显示解剖信息; 使用不减少散斑的方法或程序来处理扫描线数据，并且在一个扫描序列期间，同时获取两条扫描线数据，该数据被处理减少斑点，并且该数据被处理而不减少斑点。

8. 发明申请

US20080288218A1 Using Tissue Acceleration to Create Better Dti Waveforms (Doppler Tissue Imaging) for Crt (Cardiac Resynchronization Therapy) 审中-公开
标题翻译：使用组织加速创建更好的Dti波形（多普勒组织成像）用于Crt（心脏再同步治疗）
公开(公告)号：US20080288218A1
公开(公告)日：2008-11-20
申请号：US12091772
申请日：2006-10-24
申请人： Karl E. Thiele
发明人： Karl E. Thiele
IPC分类号： H04B15/00
CPC分类号： G01S15/8979 , A61B8/0883 , A61B8/485 , A61B8/488 , G01S7/52042 , G01S7/52085 , G01S15/582 , G01S15/8977
摘要： The present invention allows one to reconstruct high quality velocity waveforms using data collected at comparatively slow frame rates, such data would have otherwise resulted in non-diagnostic and non-clinically useful waveforms. The invention is directed to reconstructing a high quality “continuous” velocity waveform, and uses instantaneous measures of acceleration in addition to velocity to reconstruct such a waveform. By simultaneously detecting the velocity and acceleration of a fixed point in space, one can more faithfully reproduce the corresponding velocity waveform using significantly lower sample rates. If images are acquired, then the velocity sample rate corresponds to the image frame rate. Also, depending on the number of looks or scan lines contained in an ensemble, double interleaving of the raw data is used.
摘要翻译：本发明允许使用以相对较慢的帧速率收集的数据来重构高质量的速度波形，否则这样的数据将导致非诊断和非临床上有用的波形。本发明旨在重建高质量的“连续”速度波形，并且除了速度之外还使用加速度的瞬时测量来重建这样的波形。通过同时检测空间中固定点的速度和加速度，可以使用显着较低的采样率更真实地再现相应的速度波形。如果获取图像，则速度采样率对应于图像帧速率。另外，根据集合中包含的外观或扫描线的数量，使用原始数据的双交错。

9. 发明授权

US06689064B2 Ultrasound clutter filter 失效
标题翻译：超声波杂波滤波器
公开(公告)号：US06689064B2
公开(公告)日：2004-02-10
申请号：US09887648
申请日：2001-06-22
申请人： Richard A Hager , David W Clark , Karl E Thiele , Jerome F Witt
发明人： Richard A Hager , David W Clark , Karl E Thiele , Jerome F Witt
IPC分类号： A61B812
CPC分类号： G01S15/8981 , G01S7/52026
摘要： A method for adaptive filtering of clutter from a sample stream having a blood signal component and a clutter signal component comprises the steps of (a) estimating a signal strength of the sample stream, and (b) determining an order of a filter based on a relationship between the signal strength estimate and a signal strength threshold. The filter receives the sample stream and provides an output stream having a reduced level of the clutter signal component relative to the blood signal component.
摘要翻译：一种用于从具有血液信号分量和杂波信号分量的样本流自适应滤波杂波的方法包括以下步骤：（a）估计样本流的信号强度，以及（b）基于以下步骤确定滤波器的顺序：信号强度估计与信号强度阈值之间的关系。滤波器接收采样流并提供相对于血液信号分量具有降低的杂波信号分量电平的输出流。

10. 发明授权

US5993390A Segmented 3-D cardiac ultrasound imaging method and apparatus 有权
标题翻译：分段3-D心脏超声成像方法和装置
公开(公告)号：US5993390A
公开(公告)日：1999-11-30
申请号：US156110
申请日：1998-09-18
申请人： Bernard J. Savord , Karl E. Thiele
发明人： Bernard J. Savord , Karl E. Thiele
IPC分类号： A61B5/0402 , A61B8/08 , G01S15/89 , A61B8/00
CPC分类号： G01S15/8993 , A61B8/08 , A61B8/0883 , A61B8/483 , G01S7/52087 , G01S7/52088 , G01S7/52095 , A61B5/0402 , A61B8/543 , Y10S128/916
摘要： Ultrasound image data representative of three-dimensional volume segments of an image volume of interest is acquired in synchronism with corresponding cardiac cycles of a patient. The image data representative of the volume segments is combined to provide image data representative of a three-dimensional image of the image volume. The image data acquisition may be synchronized to a selected phase of the patient's cardiac cycle, so that the image represents the image volume at the selected phase. Image data for a three-dimensional volume segment may be acquired during each of the cardiac phases of a cardiac cycle.
摘要翻译：与患者的相应心动周期同步地获取表示感兴趣图像体积的三维体积段的超声图像数据。代表音量段的图像数据被组合以提供表示图像体积的三维图像的图像数据。图像数据采集可以被同步到患者心脏周期的所选阶段，使得图像表示在选定阶段的图像体积。可以在心脏周期的每个心脏阶段期间获取用于三维体积段的图像数据。

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