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1. 发明申请

US20150010037A1 RESTRICTIONS ON THE VALIDITY OF THERMAL CONDITIONS AT A POROUS FLUID INTERFACE AND ITS APPLICATIONS 审中-公开
标题翻译：多孔流体界面热条件有效性限制及其应用
公开(公告)号：US20150010037A1
公开(公告)日：2015-01-08
申请号：US13935659
申请日：2013-07-05
申请人： Kambiz Vafai , Kun Yang
发明人： Kambiz Vafai , Kun Yang
IPC分类号： G01K17/06
CPC分类号： G01K17/20
摘要： A method and system for analyzing variant thermal conditions at the porous-fluid interface under LTNE condition is disclosed. Exact solutions can be derived for both the fluid and solid temperature distributions for the most fundamental forms of thermal conditions at the interface between a porous medium and a fluid under LTNE conditions and the relationships between these solutions are obtained. The range of validity of all the models can be analyzed. Also, a critical non-dimensional half height of the porous media is determined, below which the LTE condition within porous region is considered to be valid. Furthermore, the range of validity of the LTE condition can be obtained based on the introduction of a critical parameter.
摘要翻译：公开了一种用于在LTNE条件下分析多孔 - 液界面处的变形热条件的方法和系统。可以为在LTNE条件下多孔介质和流体之间的界面处的最基本形式的热条件的流体和固体温度分布求出精确的解，并且获得这些溶液之间的关系。可以分析所有模型的有效范围。此外，确定多孔介质的关键无量纲半高度，低于此高多孔区域内的LTE条件被认为是有效的。此外，可以基于引入关键参数来获得LTE条件的有效范围。

2. 发明授权

US08814057B2 Minimizing flow disturbances in fluidic cells utilizing soft seals 有权
标题翻译：使用软密封最小化流体池中的流动干扰
公开(公告)号：US08814057B2
公开(公告)日：2014-08-26
申请号：US13039417
申请日：2011-03-03
申请人： Kambiz Vafai , Abdul Rahim A. Khaled
发明人： Kambiz Vafai , Abdul Rahim A. Khaled
IPC分类号： G05D23/00
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00804 , B01J2219/00864 , B01J2219/00873 , B01L3/502746 , B01L7/00 , B01L2300/0874 , B01L2400/0633 , B01L2400/082 , B82Y30/00 , F23C2900/03001 , F23N2900/01001 , F28F2230/00
摘要： Devices comprising multi-compartment fluidic cell with multiple inlets. Compartments can be separated from one another using soft seals. The main cell can be located between two adjacent secondary cells. The main cell carries the main flow while the secondary cells can carry either the main flow or any auxiliary flows. The flow in the multi-compartment cells minimizes fluid leakage and causes reduced pressure difference between the main cell and the two secondary cells especially under similar flow conditions.
摘要翻译：包括具有多个入口的多室流体池的装置。隔间可以使用软密封相互分离。主电池可以位于两个相邻的二次电池之间。主电池承载主流，而二次电池可承载主流或任何辅助流。多腔室细胞中的流动使流体泄漏最小化，并且导致主电池和两个二次电池之间的压力差异降低，特别是在相似的流动条件下。

3. 发明授权

US08684274B2 Cooling enhancements in thin films using flexible complex seal due to temperature increase or thermal load increase 失效
标题翻译：由于温度升高或热负荷增加，使用柔性复合密封的薄膜中的冷却增强
公开(公告)号：US08684274B2
公开(公告)日：2014-04-01
申请号：US13026477
申请日：2011-02-14
申请人： Kambiz Vafai , Abdul Rahim A. Khaled
发明人： Kambiz Vafai , Abdul Rahim A. Khaled
IPC分类号： G05D23/00
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00804 , B01J2219/00808 , B01J2219/00864 , B01J2219/00873 , B01L3/502746 , B01L7/54 , B01L2300/0874 , B01L2300/1838 , B01L2300/185 , B01L2300/1883 , B01L2400/082 , B82Y30/00 , F23C2900/03001 , F23N2900/01001 , F28F2230/00
摘要： A cooling enhancement apparatus includes a first substrate and a second substrate, the first substrate having a face in contact with at least one hot medium and having another face in contact with a secondary gas. The second substrate includes a face in contact with the secondary gas and has the other face in contact with a main gas. The faces of the first and second substrates in contact with the secondary gas generally oppose each other. One or more flexible seals can be attached to the first substrate and to the second substrate to form one or more closed enclosures including the secondary gas so that the second substrate moves relative to the first substrate when the secondary gas undergoes volumetric thermal expansion.
摘要翻译：冷却增强装置包括第一基板和第二基板，第一基板具有与至少一个热介质接触的面并具有与二次气体接触的另一面。第二基板包括与二次气体接触的面，并且另一面与主气体接触。与第二气体接触的第一和第二基板的表面通常彼此相对。可以将一个或多个柔性密封件附接到第一基板和第二基板，以形成包括二次气体的一个或多个封闭外壳，使得当二次气体经历体积热膨胀时，第二基板相对于第一基板移动。

4. 发明申请

US20110155364A1 SMART PASSIVE THERMAL DEVICES AND METHODS 失效
标题翻译：智能被动热装置和方法
公开(公告)号：US20110155364A1
公开(公告)日：2011-06-30
申请号：US13044029
申请日：2011-03-09
申请人： Kambiz Vafai , Abdul Rahim Assaad Khaled
发明人： Kambiz Vafai , Abdul Rahim Assaad Khaled
IPC分类号： F28F7/00
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00804 , B01J2219/00864 , B01J2219/00873 , B01L3/502746 , B01L7/00 , B01L2300/1838 , B01L2400/0633 , B01L2400/082 , B82Y30/00 , F16K99/0001 , F16K99/0036 , F16K2099/008 , F23C2900/03001 , F23N2900/01001 , F28D9/00 , F28F2230/00 , F28F2260/02 , F28F2265/26
摘要： Devices and methods for increasing and decreasing cooling capacity as thermal load increases by utilizing bimaterial. For increasing the cooling capacity, the upper plate of a thin film microchannel can be configured from a bimaterial, such that the upper layer possesses a higher linear thermal expansion coefficient than that of the lower layer material. Excessive heating causes the coolant temperature to increase which in turn heats the upper plate. As such, the upper plate bends outward allowing for more coolant to flow within the thin film. For decreasing the cooling capacity, the upper plate can be configured from a bimaterial such that its lower layer has a higher linear thermal expansion coefficient than that of the upper layer material. Excessive heating can cause the coolant temperature to increase, which in turn heats the upper plate. As such, the upper plate can bend inward resulting in less coolant flow within the thin film.
摘要翻译：随着热负荷的增加，通过利用双材料来增加和降低冷却能力的装置和方法。为了增加冷却能力，薄膜微通道的上板可以由双材料构成，使得上层具有比下层材料更高的线性热膨胀系数。过热会导致冷却液温度升高，反过来加热上板。因此，上板向外弯曲，允许更多的冷却剂在薄膜内流动。为了降低冷却能力，上板可以由双材料构成，使得其下层具有比上层材料更高的线性热膨胀系数。过热会导致冷却液温度升高，从而加热上板。因此，上板可以向内弯曲，导致薄膜内的冷却剂流动更少。

5. 发明申请

US20070141721A1 MICROCANTILEVERS FOR BIOLOGICAL AND CHEMICAL ASSAYS AND METHODS OF MAKING AND USING THEREOF 失效
标题翻译：生物和化学测定微生物及其制备和使用方法
公开(公告)号：US20070141721A1
公开(公告)日：2007-06-21
申请号：US10422776
申请日：2003-04-25
申请人： Kambiz Vafai , Cengiz Ozkan , Robert Haddon , Abdul-Rahim Khaled , Mo Yang
发明人： Kambiz Vafai , Cengiz Ozkan , Robert Haddon , Abdul-Rahim Khaled , Mo Yang
IPC分类号： G01N33/543
CPC分类号： G01N33/54373 , B82Y30/00
摘要： Disclosed herein are microcantilevers having structural shapes that are less sensitive to turbulence and drift effects yet provide greater deflections due to analyte concentration. The structural shapes include a C-shaped microcantilever, an E-shaped microcantilever, an L-shaped microcantilever, a double microcantilever, a slit microcantilever, a tapered microcantilever, and a triangular microcantilever. The microcantilevers may be piezoresistive microcantilevers. Also disclosed are microsensors, microfludic devices, and biochips that comprise the microcantilevers as well as methods of using the microcantilevers to detect analytes in a fluid sample.
摘要翻译：本文公开了具有对湍流和漂移效应较不敏感但具有由于分析物浓度引起的更大偏转的结构形状的微悬臂梁。结构形状包括C形微悬臂梁，E形微悬臂梁，L形微悬臂梁，双微悬臂梁，狭缝微悬臂梁，锥形微悬臂梁和三角形微悬臂梁。微悬臂梁可以是压阻微型悬臂梁。还公开了包含微悬臂梁的微传感器，微流体装置和生物芯片以及使用微悬臂梁来检测流体样品中的分析物的方法。

6. 发明授权

US08690073B2 Control of flow rate and thermal conditions using two-layered thin films separated by flexible seals and rotatable pivot 失效
标题翻译：使用由柔性密封件和可旋转枢轴分隔的两层薄膜控制流量和热条件
公开(公告)号：US08690073B2
公开(公告)日：2014-04-08
申请号：US13032049
申请日：2011-02-22
申请人： Kambiz Vafai , Abdul-Rahim Assaad Khaled
发明人： Kambiz Vafai , Abdul-Rahim Assaad Khaled
IPC分类号： G05D23/00
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00804 , B01J2219/00808 , B01J2219/00864 , B01J2219/00873 , B01J2219/00876 , B01L3/502746 , B01L7/00 , B01L2300/0874 , B01L2400/0633 , B01L2400/082 , B82Y30/00 , F23C2900/03001 , F23N2900/01001 , F28F3/10 , F28F13/00 , F28F2230/00
摘要： Devices for the control of flow rate and thermal conditions using two-layered thin films separated by flexible complex seals. The plates of an upper thin film are separated by a sealing assembly. The sealing assembly is composed of an elastic soft seal separating closed voids of stagnant fluid and in contact with the upper plate of the device as it is the heated plate. The lower and the upper plates of the lower thin film can be separated by an elastic soft seal. The lower and upper thin films are named as main and secondary layers, respectively. Both the upper plate of the secondary layer and the lower plate of the main layer are fixed while the intermediate plate and is free to move in the vertical direction. When the pressure or the working temperature in the secondary layer increases, the secondary layer expands causing the main layer thickness to shrink. This reduces the main layer flow rate and temperature gradients within the main layer.
摘要翻译：用于通过柔性复合密封分隔的双层薄膜来控制流速和热条件的装置。上薄膜的板由密封组件分开。密封组件由弹性软密封件组成，分离闭合的滞留流体空隙并与设备的上板接触，因为它是加热板。下薄膜的下板和上板可通过弹性软密封分开。下层和上层薄膜分别命名为主层和二层。二层的上板和主层的下板均固定在中间板上，并且在垂直方向上自由移动。当二次层中的压力或工作温度升高时，二次层膨胀，使主层厚度收缩。这降低了主层内的主层流量和温度梯度。

7. 发明申请

US20120174268A1 ASSEMBLY OF MICROCANTILEVER-BASED SENSORS WITH ENHANCED DEFLECTIONS 审中-公开
标题翻译：具有增强偏差的基于微处理器的传感器的组装
公开(公告)号：US20120174268A1
公开(公告)日：2012-07-05
申请号：US13247169
申请日：2011-09-28
申请人： Kambiz Vafai , Abdul Rahlm A. Khaled
发明人： Kambiz Vafai , Abdul Rahlm A. Khaled
IPC分类号： G01Q70/08 , G01Q70/16
CPC分类号： G01N29/022 , G01N2291/0255 , G01N2291/0256 , G01N2291/0427
摘要： An assembly of microcantilever-based sensors with enhanced deflections. A deflection profile of an ε-assembly can be compared with that of a rectangular microcantilever and a modified triangular microcantilever. Various force-loading conditions can also be considered. A theorem of linear elasticity for thin beams is utilized to obtain the deflections. The obtained defections can be validated against an accurate numerical solution utilizing a finite element method with a maximum deviation of less than 10 percent. The ε-assembly produces larger deflections than the rectangular microcantilever under the same base surface stress and same extension length. Also, the ε-microcantilever assembly produces a larger deflection than a modified triangular microcantilever. The deflection enhancement increases as the ε-assembly's free length decreases for various types of force loading conditions. The ε-microcantilever can be utilized in microsensing applications to provide a favorable high detection capability with a reduced susceptibility to external noises.
摘要翻译：具有增强偏转的基于微型悬臂梁的传感器组件。可以将组装的偏转轮廓与矩形微悬臂梁和改进的三角形微悬臂梁的偏转轮廓进行比较。也可以考虑各种力加载条件。利用薄梁的线性弹性定理来获得偏转。获得的偏差可以使用最大偏差小于10％的有限元法进行精确数值解。在相同的基础表面应力和相同的延伸长度下，该组件产生比矩形微悬臂梁更大的偏转。此外，微型悬臂梁组件产生比改进的三角形微悬臂梁更大的偏转。随着各种类型的力加载条件下，组件的自由长度减小，挠度增强将增加。微型悬臂梁可用于微型应用中，以提供有利的高检测能力，降低对外部噪声的敏感性。

8. 发明授权

US08172156B2 Thin film based microfluidic devices 有权
标题翻译：基于薄膜的微流体装置
公开(公告)号：US08172156B2
公开(公告)日：2012-05-08
申请号：US12793826
申请日：2010-06-04
申请人： Kambiz Vafai , Abdul Rahim Assaad Khaled
发明人： Kambiz Vafai , Abdul Rahim Assaad Khaled
IPC分类号： G05D23/12
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00804 , B01J2219/00864 , B01J2219/00873 , B82Y30/00 , F16J15/064 , F23C2900/03001 , F23N2900/01001 , F28F3/10 , F28F3/12 , F28F13/00 , F28F2230/00 , G05D23/02
摘要： Disclosed herein are devices comprising at least one flexible seal, at least one flexible complex seal having at least one closed cavity containing a fluid, or a combination thereof. The devices may comprise at least one immobile and inflexible substrate and at least one mobile and inflexible substrate capable of movement due to the flexible seal, the flexible complex seal, or both. The flexible complex seals comprise at least one closed cavity comprising a fluid, such as a gas or a liquid. As disclosed, the presence or absence of heat will cause the mobile and inflexible substrate to move. The movement will increase or decrease the fluid amount or fluid flow rate in the primary fluid layer. Also disclosed are methods for enhancing the insulating properties of insulating assemblies.
摘要翻译：本文公开了包括至少一个柔性密封件，至少一个具有至少一个包含流体的封闭空腔的柔性复合密封件或其组合的装置。所述装置可以包括至少一个不动和不灵活的基底以及能够由于柔性密封，柔性复合物密封或两者而能够运动的至少一个移动和不灵活的基底。柔性复合物密封件包括至少一个包含诸如气体或液体的流体的封闭空腔。如所公开的，存在或不存在热将导致移动和不灵活的基板移动。移动将增加或减少主流体层中的流体量或流体流速。还公开了用于增强绝缘组件的绝缘性能的方法。

9. 发明授权

US09170060B2 Rapid microfluidic thermal cycler for nucleic acid amplification 有权
标题翻译：用于核酸扩增的快速微流体热循环仪
公开(公告)号：US09170060B2
公开(公告)日：2015-10-27
申请号：US12270348
申请日：2008-11-13
申请人： Neil Reginald Beer , Kambiz Vafai
发明人： Neil Reginald Beer , Kambiz Vafai
IPC分类号： C12M1/00 , C12M3/00 , F28F13/00 , B01L7/00 , F28F3/12 , B01L3/00
CPC分类号： F28F13/003 , B01L3/5023 , B01L3/502784 , B01L7/52 , B01L2300/0636 , B01L2300/0816 , B01L2300/0838 , B01L2300/1838 , B01L2300/185 , F28F3/12 , F28F2260/02
摘要： A system for thermal cycling a material to be thermal cycled including a microfluidic heat exchanger; a porous medium in the microfluidic heat exchanger; a microfluidic thermal cycling chamber containing the material to be thermal cycled, the microfluidic thermal cycling chamber operatively connected to the microfluidic heat exchanger; a working fluid at first temperature; a first system for transmitting the working fluid at first temperature to the microfluidic heat exchanger; a working fluid at a second temperature, a second system for transmitting the working fluid at second temperature to the microfluidic heat exchanger; a pump for flowing the working fluid at the first temperature from the first system to the microfluidic heat exchanger and through the porous medium; and flowing the working fluid at the second temperature from the second system to the heat exchanger and through the porous medium.
摘要翻译：一种用于热循环待热循环的材料的系统，包括微流体热交换器; 微流体换热器中的多孔介质; 微流体热循环室，其容纳要热循环的材料，微流体热循环室可操作地连接到微流体热交换器; 第一温度下的工作液; 用于将第一温度下的工作流体传送到微流体热交换器的第一系统; 在第二温度下的工作流体，用于在第二温度将工作流体传送到微流体热交换器的第二系统; 用于使工作流体在第一温度从第一系统流动到微流体热交换器并通过多孔介质的泵; 并使工作流体在第二温度从第二系统流动到热交换器并通过多孔介质。

10. 发明授权

US08714461B2 Enhancing insulating properties at higher temperature utilizing soft seals 失效
标题翻译：使用软密封增强高温下的绝缘性能
公开(公告)号：US08714461B2
公开(公告)日：2014-05-06
申请号：US13030319
申请日：2011-02-18
申请人： Kambiz Vafai , Abdul-Rahim Assaad Khaled
发明人： Kambiz Vafai , Abdul-Rahim Assaad Khaled
IPC分类号： G05D23/00
CPC分类号： B01J19/0093 , B01J2219/00783 , B01J2219/00804 , B01J2219/00864 , B01J2219/00873 , B01L3/502746 , B01L7/00 , B01L2300/0874 , B01L2400/082 , B82Y30/00 , F23C2900/03001 , F23N2900/01001 , F28D9/00 , F28F2230/00 , F28F2260/02 , Y10T137/36
摘要： Devices utilized to enhance insulating properties at high temperatures. Such devices can include two gas compartments. A main gas compartment can function as a main layer and generally contains a layer of a gas (e.g., Xenon) having a relatively small thermal conductivity. The plates of the main gas layer can be separated by a soft seal, so that the main gas does not leak and the main layer expands easily. A second gas compartment can be configured as a vented compartment filled with air. At high temperatures, the main gas expands while the secondary gas volume shrinks. Since the main gas possesses a lower thermal conductivity, the effective resistance of the device increases, causing an enhancement in the insulating properties at large operating temperatures. A series of gas compartments can be utilized for additional enhancement in insulating properties.
摘要翻译：用于提高高温绝缘性能的器件。这样的装置可以包括两个气室。主气室可用作主层，并且通常包含具有相对较小导热性的气体层（例如氙）。主气层的板可以通过软密封分开，主气不泄漏，主层容易膨胀。第二气室可以被配置为充满空气的排气室。在高温下，主气体膨胀，二次气体体积缩小。由于主气体具有较低的热导率，所以器件的有效电阻增加，导致在大的工作温度下绝缘性能的提高。可以使用一系列气体室来进一步提高绝缘性能。

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