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    • 2. 发明申请
    • PROCESS FOR PREPARING OF N-METHYL PYRROLIDONE
    • 制备N-甲基吡咯烷酮的方法
    • WO2009082086A1
    • 2009-07-02
    • PCT/KR2008/005790
    • 2008-10-01
    • ISU CHEMICAL CO., LTD.OH, In-ChulKIM, Chang-GookRHIE, Dae-YongKIM, Lee-HoKIM, Jun-SooKIM, Soo-HyunHWANG, Chan-KooROH, Myung-HunJUNG, Jin-Su
    • OH, In-ChulKIM, Chang-GookRHIE, Dae-YongKIM, Lee-HoKIM, Jun-SooKIM, Soo-HyunHWANG, Chan-KooROH, Myung-HunJUNG, Jin-Su
    • C07D207/267
    • C07D207/267
    • The present invention relates to a process for preparation of N-methyl pyrrolidone, and more particularly to a process for preparing high purity, high yield N-methyl pyrrolidone, comprising a first step of dehydrogenating 1,4-butandiol under a hydrogen atmosphere in the presence of a metal oxide solid catalyst to prepare γ-butyrolactone, and a second step of subjecting the γ-butyrolactone obtained in the first step without purification to a dehydration with monomethylamine under a metal oxide solid catalyst. The process for preparation of N-methyl pyrrolidone according to the present invention is a continuous two-step process using a metal oxide catalyst, wherein the second step continuously progresses without purification of the reaction product of the first step, γ-butyrolactone. According to the present invention, little of a reaction intermediate γ-butyrolactone, which is difficult to separate because of a small difference in boiling point (about 2 "C) from the final product, N-methyl pyrrolidone, remains after reaction, and thus separation and purification are easy. Further, its simple process enables mass production and lowers purification equipment cost.
    • 本发明涉及一种制备N-甲基吡咯烷酮的方法,更具体地说涉及一种制备高纯度高产率N-甲基吡咯烷酮的方法,该方法包括在氢气气氛下使1,4-丁二醇脱氢的第一步骤 存在金属氧化物固体催化剂以制备γ-丁内酯,第二步是在金属氧化物固体催化剂下,不经纯化使第一步得到的γ-丁内酯与单甲胺脱水。 根据本发明的制备N-甲基吡咯烷酮的方法是使用金属氧化物催化剂的连续两步法,其中第二步连续进行而不净化第一步反应产物γ-丁内酯。 根据本发明,由于与最终产物N-甲基吡咯烷酮的沸点差大(约2℃)难以分离的γ-丁内酯中间体很少反应后残留,因此, 分离和净化容易,而且简单的过程使得批量生产和降低净化设备成本。