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1. 发明申请

US20100175153A1 REGULATING THE ETHYLENE RESPONSE OF A PLANT BY MODULATION OF F-BOX PROTEINS 有权
标题翻译：通过调节F-BOX蛋白调节植物的乙烯反应
公开(公告)号：US20100175153A1
公开(公告)日：2010-07-08
申请号：US12643033
申请日：2009-12-21
申请人： Hongwei Guo , Joseph R. Ecker
发明人： Hongwei Guo , Joseph R. Ecker
IPC分类号： A01H5/00
CPC分类号： C12N15/8291 , C12N15/8249 , C12N15/8261 , C12N15/8266 , C12N15/8267 , C12N15/8271
摘要： The relationship between F-box proteins and proteins involved in the ethylene response in plants is described. In particular, F-box proteins may bind to proteins involved in the ethylene response and target them for degradation by the ubiquitin/proteasome pathway. The transcription factor EIN3 is a key transcription factor mediating ethylene-regulated gene expression and morphological responses. EIN3 is degraded through a ubiquitin/proteasome pathway mediated by F-box proteins EBF1 and EBF2. The link between F-box proteins and the ethylene response is a key step in modulating or regulating the response of a plant to ethylene. Described herein are transgenic plants having an altered sensitivity to ethylene, and methods for making transgenic plant having an altered sensitivity to ethylene by modulating the level of activity of F-box proteins. Methods of altering the ethylene response in a plant by modulating the activity or expression of an F-box protein are described. Also described are methods of identifying compounds that modulate the ethylene response in plants by modulating the level of F-box protein expression or activity.
摘要翻译：描述了F-box蛋白和参与植物乙烯应答的蛋白质之间的关系。特别地，F盒蛋白可能与参与乙烯应答的蛋白结合，并将其靶向通过泛素/蛋白酶体途径降解。转录因子EIN3是介导乙烯调节基因表达和形态学反应的关键转录因子。 EIN3通过F-box蛋白EBF1和EBF2介导的泛素/蛋白酶体途径降解。 F-box蛋白与乙烯反应之间的联系是调节或调节植物对乙烯的反应的关键步骤。本文描述了对乙烯具有改变的敏感性的转基因植物，以及通过调节F-box蛋白的活性水平来制备对乙烯具有改变的敏感性的转基因植物的方法。描述了通过调节F盒蛋白的活性或表达来改变植物中的乙烯应答的方法。还描述了通过调节F-box蛋白表达或活性的水平鉴定调节植物中乙烯应答的化合物的方法。

2. 发明授权

US07169972B2 Methods and compositions to modulate ethylene sensitivity 有权
标题翻译：调节乙烯敏感性的方法和组成
公开(公告)号：US07169972B2
公开(公告)日：2007-01-30
申请号：US10142638
申请日：2002-05-08
申请人： Anna N. Stepanova , Joseph R. Ecker
发明人： Anna N. Stepanova , Joseph R. Ecker
IPC分类号： C12N15/01 , C12N15/82 , A01H5/00
CPC分类号： A01H5/00 , C07K14/415 , C12N15/8249 , C12N15/8291
摘要： The field of the invention relates to plants and plant genes, including both plant mutants and transgenic plants containing a gene that confers an ethylene insensitive phenotype. Also encompassed by the invention are methods of using the disclosed plant gene to confer an ethylene insensitive phenotype.
摘要翻译：本发明的领域涉及植物和植物基因，包括植物突变体和含有赋予乙烯不敏感表型的基因的转基因植物。本发明还包括使用所公开的植物基因赋予乙烯不敏感表型的方法。

3. 发明授权

US5367065A Constitutive triple response gene and mutations 失效
标题翻译：组成型三重反应基因和突变
公开(公告)号：US5367065A
公开(公告)日：1994-11-22
申请号：US928464
申请日：1992-08-10
申请人： Joseph R. Ecker , Joseph J. Kieber
发明人： Joseph R. Ecker , Joseph J. Kieber
IPC分类号： C07K14/415 , C12N15/82 , C07H17/00 , C07H21/04 , C12N15/00
CPC分类号： C12N15/8249 , C07K14/415 , C12N15/8279
摘要： The present invention is directed to nucleic acid sequences for constitutive triple response mutants and corresponding amino acid sequences. Several ctr mutations are included within the scope of the present invention. The nucleic acid sequences set forth in SEQUENCE ID NUMBERS 1, and 3-6 as well as amino acid sequences set forth in SEQUENCE ID NUMBERS 1 and 2 are particular embodiments of the present invention.
摘要翻译：本发明涉及组成型三重反应突变体和相应氨基酸序列的核酸序列。在本发明的范围内包括几个ctr突变。 SEQUENCE ID NUMBERS 1和3-6中阐述的核酸序列以及SEQUENCE ID NUMBERS 1和2中所示的氨基酸序列是本发明的特定实施方案。

4. 发明授权

US09000260B2 ETP1 and ETP2 regulate plant ethylene response 有权
标题翻译： ETP1和ETP2调节植物乙烯反应
公开(公告)号：US09000260B2
公开(公告)日：2015-04-07
申请号：US12729760
申请日：2010-03-23
申请人： Hong Qiao , Joseph R. Ecker
发明人： Hong Qiao , Joseph R. Ecker
IPC分类号： A01H1/00 , A01H5/00 , C12N5/04 , C12N15/82 , C07K14/415 , C12N15/10
CPC分类号： C12N15/8271 , A01H5/00 , C07K14/415 , C12N15/1048 , C12N15/8201 , C12N15/8218 , C12N15/8249 , C12N15/8262
摘要： ETP1 and ETP2 bind to EIN2 and modulate plant ethylene sensitivity.
摘要翻译： ETP1和ETP2结合EIN2并调节植物乙烯敏感性。

5. 发明授权

US07902422B2 Regulating the ethylene response of a plant by modulation of F-box proteins 有权
标题翻译：通过调节F盒蛋白来调节植物的乙烯应答
公开(公告)号：US07902422B2
公开(公告)日：2011-03-08
申请号：US12643033
申请日：2009-12-21
申请人： Hongwei Guo , Joseph R. Ecker
发明人： Hongwei Guo , Joseph R. Ecker
IPC分类号： A01H1/00 , A01H5/00 , C12N15/09 , C12N15/82
CPC分类号： C12N15/8291 , C12N15/8249 , C12N15/8261 , C12N15/8266 , C12N15/8267 , C12N15/8271
摘要： The invention relates to transgenic plants having reduced sensitivity to ethylene as a result of having a recombinant nucleic acid encoding an F-box protein that interacts with a EIN3 involved in an ethylene response of plants, and a method of producing a transgenic plant with reduced ethylene sensitivity by transforming the plant with a nucleic acid sequence encoding an F-box protein. The inventions also relates to methods of altering the ethylene response in a plant by modulating the activity or expression of an F-box protein.
摘要翻译：本发明涉及具有降低的对乙烯的敏感性的转基因植物，其具有编码与参与植物乙烯应答的EIN3相互作用的F盒蛋白的重组核酸的结果，以及生产具有还原型乙烯的转基因植物的方法通过用编码F盒蛋白的核酸序列转化植物的灵敏度。本发明还涉及通过调节F盒蛋白的活性或表达来改变植物中的乙烯应答的方法。

6. 发明授权

US07655835B2 Regulating the ethylene response of a plant by modulation of F-box proteins 有权
标题翻译：通过调节F盒蛋白来调节植物的乙烯应答
公开(公告)号：US07655835B2
公开(公告)日：2010-02-02
申请号：US11298286
申请日：2005-12-09
申请人： Hongwei Guo , Joseph R. Ecker
发明人： Hongwei Guo , Joseph R. Ecker
IPC分类号： C12N15/82 , C12N15/09 , A01H1/00
CPC分类号： C12N15/8291 , C12N15/8249 , C12N15/8261 , C12N15/8266 , C12N15/8267 , C12N15/8271
摘要： The invention relates to transgenic plants having reduced sensitivity to ethylene as a result of having a recombinant nucleic acid encoding a F-box protein, and a method of producing a transgenic plant with reduced ethylene sensitivity by transforming the plant with a nucleic acid sequence encoding a F-box protein.
摘要翻译：本发明涉及由于具有编码F盒蛋白的重组核酸而对乙烯具有降低的敏感性的转基因植物，以及通过用编码一个或多个核苷酸序列的核酸序列转化植物来生产具有降低的乙烯敏感性的转基因植物的方法 F盒蛋白。

7. 发明授权

US5674701A Method of identifying plant pathogen tolerance 失效
标题翻译：识别植物病原体耐受性的方法
公开(公告)号：US5674701A
公开(公告)日：1997-10-07
申请号：US171207
申请日：1993-12-21
申请人： Joseph R. Ecker , Brian J. Staskawicz , Andrew F. Bent , Roger W. Innes
发明人： Joseph R. Ecker , Brian J. Staskawicz , Andrew F. Bent , Roger W. Innes
IPC分类号： A01H1/04 , C07K14/415 , C12N5/04 , C12N15/82 , G01N33/50 , G01N33/569 , C12Q1/18 , A01H5/00
CPC分类号： G01N33/56961 , A01H1/04 , C07K14/415 , C12N15/8249 , C12N15/8281 , C12N5/04 , G01N33/5097
摘要： A process for identifying a plant having disease tolerance comprising administering to a plant an inhibitory amount of ethylene and screening for ethylene insensitivity, thereby identifying a disease tolerant plant, is described. Plants identified by the foregoing process are also described.
摘要翻译：用于鉴定具有疾病耐受性的植物的方法包括向植物施用抑制量的乙烯并筛选乙烯不敏感性，从而鉴定耐病植物。还描述了通过前述方法鉴定的植物。

8. 发明申请

US20110131688A1 REGULATING THE ETHYLENE RESPONSE OF A PLANT BY MODULATION OF F-BOX PROTEINS 有权
标题翻译：通过调节F-BOX蛋白调节植物的乙烯反应
公开(公告)号：US20110131688A1
公开(公告)日：2011-06-02
申请号：US13015333
申请日：2011-01-27
申请人： Hongwei Guo , Joseph R. Ecker
发明人： Hongwei Guo , Joseph R. Ecker
IPC分类号： A01H5/00
CPC分类号： C12N15/8291 , C12N15/8249 , C12N15/8261 , C12N15/8266 , C12N15/8267 , C12N15/8271
摘要： The relationship between F-box proteins and proteins involved in the ethylene response in plants is described. In particular, F-box proteins may bind to proteins involved in the ethylene response and target them for degradation by the ubiquitin/proteasome pathway. The transcription factor EIN3 is a key transcription factor mediating ethylene-regulated gene expression and morphological responses. EIN3 is degraded through a ubiquitin/proteasome pathway mediated by F-box proteins EBF1 and EBF2. The link between F-box proteins and the ethylene response is a key step in modulating or regulating the response of a plant to ethylene. Described herein are transgenic plants having an altered sensitivity to ethylene, and methods for making transgenic plant having an altered sensitivity to ethylene by modulating the level of activity of F-box proteins. Methods of altering the ethylene response in a plant by modulating the activity or expression of an F-box protein are described. Also described are methods of identifying compounds that modulate the ethylene response in plants by modulating the level of F-box protein expression or activity.
摘要翻译：描述了F-box蛋白和参与植物乙烯应答的蛋白质之间的关系。特别地，F盒蛋白可能与参与乙烯应答的蛋白结合，并将其靶向通过泛素/蛋白酶体途径降解。转录因子EIN3是介导乙烯调节基因表达和形态学反应的关键转录因子。 EIN3通过F-box蛋白EBF1和EBF2介导的泛素/蛋白酶体途径降解。 F-box蛋白与乙烯反应之间的联系是调节或调节植物对乙烯的反应的关键步骤。本文描述了对乙烯具有改变的敏感性的转基因植物，以及通过调节F-box蛋白的活性水平来制备对乙烯具有改变的敏感性的转基因植物的方法。描述了通过调节F盒蛋白的活性或表达来改变植物中的乙烯应答的方法。还描述了通过调节F-box蛋白表达或活性的水平鉴定调节植物中乙烯应答的化合物的方法。

9. 发明申请

US20100242135A1 ETP1 AND ETP2 REGULATE PLANT ETHYLENE RESPONSE 有权
标题翻译： ETP1和ETP2调节植物乙烯反应
公开(公告)号：US20100242135A1
公开(公告)日：2010-09-23
申请号：US12729760
申请日：2010-03-23
申请人： Hong Qiao , Joseph R. Ecker
发明人： Hong Qiao , Joseph R. Ecker
IPC分类号： A01H1/00 , G01N33/53 , C12N15/63 , A01H5/00
CPC分类号： C12N15/8271 , A01H5/00 , C07K14/415 , C12N15/1048 , C12N15/8201 , C12N15/8218 , C12N15/8249 , C12N15/8262
摘要： ETP1 and ETP2 bind to EIN2 and modulate plant ethylene sensitivity.
摘要翻译： ETP1和ETP2结合EIN2并调节植物乙烯敏感性。

10. 发明授权

US5444166A Constitutive triple response gene and mutations 失效
标题翻译：组成型三重反应基因和突变
公开(公告)号：US5444166A
公开(公告)日：1995-08-22
申请号：US3311
申请日：1993-01-12
申请人： Joseph R. Ecker , Joseph J. Kieber
发明人： Joseph R. Ecker , Joseph J. Kieber
IPC分类号： C07K14/415 , C12N15/82 , C07H17/00 , A01H5/00
CPC分类号： C12N15/8249 , C07K14/415 , C12N15/8279
摘要： The present invention is directed to nucleic acid sequences for constitutive triple response mutants and corresponding amino acid sequences. Several ctr mutations are included within the scope of the present invention. The nucleic acid sequences set forth in SEQUENCE ID NUMBERS 1, and 3-6 as well as amino acid sequences set forth in SEQUENCE ID NUMBERS 1 and 2 are particular embodiments of the present invention.
摘要翻译：本发明涉及组成型三重反应突变体和相应氨基酸序列的核酸序列。在本发明的范围内包括几个ctr突变。 SEQUENCE ID NUMBERS 1和3-6中阐述的核酸序列以及SEQUENCE ID NUMBERS 1和2中所示的氨基酸序列是本发明的特定实施方案。

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