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1. 发明专利

GB201813219D0 A safe disinfection device 未知
公开(公告)号：GB201813219D0
公开(公告)日：2018-09-26
申请号：GB201813219
申请日：2018-08-14
申请人： HONGWEI GUO , JINGHUA YE , GUOJUN SHANG

2. 外观设计

USD1028379S1 Bird house 有权
公开(公告)号：USD1028379S1
公开(公告)日：2024-05-21
申请号：US29906732
申请日：2023-11-09
申请人： Hongwei Guo
设计人： Hongwei Guo
摘要： FIG. 1 is a front, right and top perspective view of a bird house, showing my new design;
FIG. 2 is a rear, left and bottom perspective view thereof;
FIG. 3 is a front view thereof;
FIG. 4 is a rear view thereof;
FIG. 5 is a left side view thereof;
FIG. 6 is a right side view thereof;
FIG. 7 is a top plan view thereof; and,
FIG. 8 is a bottom plan view thereof.
The broken lines shown in the drawings illustrate portions of the bird house that form no part of the claimed design.

3. 发明申请

US20150176036A1 Genetically Engineered Torulopsis glabrata with Enhanced Extracellular Secretion of Pyruvic Acid 有权
标题翻译：基因工程的Torulopsis glabrata与丙酮酸的增强细胞外分泌
公开(公告)号：US20150176036A1
公开(公告)日：2015-06-25
申请号：US14185928
申请日：2014-02-21
申请人： Jian Chen , Hongwei Guo , Jingwen Zhou , Guocheng Du
发明人： Jian Chen , Hongwei Guo , Jingwen Zhou , Guocheng Du
IPC分类号： C12P7/40 , C12N15/81
CPC分类号： C12P7/40 , C07K14/195 , C12N1/16 , C12N15/815
摘要： The present invention provides a genetically engineered Torulopsis glabrata with enhanced extracellular secretion of pyruvic acid. T. glabrata strain was obtained from China Center for Type Culture Collection with CCTCC No: M202019 and over-expressed the optimized CutA (SEQ ID NO:2) encoding stress protein. Both of the temperature tolerance of T. glabrata and extracellular concentration of pyruvate were improved by overexpressing the optimized CutA. The optimum growth temperature of genetically engineered T. glabrata was increased too. The present invention can be widely used to increase extracellular levels of pyruvate during the fermentation process.
摘要翻译：本发明提供了具有增强的丙酮酸细胞外分泌的遗传工程化的Torulopsis glabrata。中华中心型号培养物中心获得T. glabrata菌株，CCTCC编号：M202019，过表达编码应激蛋白的优化的CutA（SEQ ID NO：2）。通过过度表达优化的CutA，提高了T. glabrata的温度耐受性和丙酮酸的细胞外浓度。转基因玉米的最佳生长温度也升高。本发明可广泛用于在发酵过程中增加丙酮酸的细胞外水平。

4. 发明授权

US08949743B2 Language input interface on a device 有权
标题翻译：设备上的语言输入界面
公开(公告)号：US08949743B2
公开(公告)日：2015-02-03
申请号：US12107711
申请日：2008-04-22
申请人： Yasuo Kida , Deborah Eileen Goldsmith , Elizabeth Caroline Furches , Leland Douglas Collins, Jr. , Ken Kocienda , Bas Ording , Toshiyuki Masui , Yosuke Kurita , Shin Nishibori , Takumi Takano , Hongwei Guo , Maria Celia Vigil
发明人： Yasuo Kida , Deborah Eileen Goldsmith , Elizabeth Caroline Furches , Leland Douglas Collins, Jr. , Ken Kocienda , Bas Ording , Toshiyuki Masui , Yosuke Kurita , Shin Nishibori , Takumi Takano , Hongwei Guo , Maria Celia Vigil
IPC分类号： G06F3/0481
CPC分类号： G06F3/04886 , G06F3/0234 , G06F3/0236
摘要： Methods, systems, devices, and apparatus, including computer program products, for inputting text. A user interface element is presented on a touch-sensitive display of a device. The user interface element is associated with a plurality of characters, at least a subset of which is associated with respective gestures. A user input performing a gesture with respect to the user interface element is received. The character from the subset that is associated with the gesture performed with respect to the user interface element is inputted.
摘要翻译：用于输入文本的方法，系统，设备和装置，包括计算机程序产品。用户界面元素呈现在设备的触敏显示器上。用户界面元素与多个字符相关联，其中至少一个子集与相应的手势相关联。接收相对于用户界面元素执行手势的用户输入。输入与相对于用户界面元素执行的手势相关联的子集的字符。

5. 发明授权

US08624081B2 Regulating the ethylene response of a plant by modulation of F-box proteins 有权
标题翻译：通过调节F盒蛋白来调节植物的乙烯应答
公开(公告)号：US08624081B2
公开(公告)日：2014-01-07
申请号：US13015333
申请日：2011-01-27
申请人： Hongwei Guo , Joseph R. Ecker
发明人： Hongwei Guo , Joseph R. Ecker
IPC分类号： A01H1/00 , A01H5/00 , C12N15/00 , C12N15/82
CPC分类号： C12N15/8291 , C12N15/8249 , C12N15/8261 , C12N15/8266 , C12N15/8267 , C12N15/8271
摘要： The relationship between F-box proteins and proteins involved in the ethylene response in plants is described. In particular, F-box proteins may bind to proteins involved in the ethylene response and target them for degradation by the ubiquitin/proteasome pathway. The transcription factor EIN3 is a key transcription factor mediating ethylene-regulated gene expression and morphological responses. EIN3 is degraded through a ubiquitin/proteasome pathway mediated by F-box proteins EBF1 and EBF2. The link between F-box proteins and the ethylene response is a key step in modulating or regulating the response of a plant to ethylene. Described herein are transgenic plants having an altered sensitivity to ethylene, and methods for making transgenic plant having an altered sensitivity to ethylene by modulating the level of activity of F-box proteins. Methods of altering the ethylene response in a plant by modulating the activity or expression of an F-box protein are described. Also described are methods of identifying compounds that modulate the ethylene response in plants by modulating the level of F-box protein expression or activity.
摘要翻译：描述了F-box蛋白和参与植物乙烯应答的蛋白质之间的关系。特别地，F盒蛋白可能与参与乙烯应答的蛋白结合，并将其靶向通过泛素/蛋白酶体途径降解。转录因子EIN3是介导乙烯调节基因表达和形态学反应的关键转录因子。 EIN3通过F-box蛋白EBF1和EBF2介导的泛素/蛋白酶体途径降解。 F-box蛋白与乙烯反应之间的联系是调节或调节植物对乙烯的反应的关键步骤。本文描述了对乙烯具有改变的敏感性的转基因植物，以及通过调节F-box蛋白的活性水平来制备对乙烯具有改变的敏感性的转基因植物的方法。描述了通过调节F盒蛋白的活性或表达来改变植物中的乙烯应答的方法。还描述了通过调节F-box蛋白表达或活性的水平鉴定调节植物中乙烯应答的化合物的方法。

6. 外观设计

USD1017913S1 Bird house 有权
公开(公告)号：USD1017913S1
公开(公告)日：2024-03-12
申请号：US29906731
申请日：2023-11-09
申请人： Hongwei Guo
设计人： Hongwei Guo
摘要： FIG. 1 is a front, right and top perspective view of a bird house, showing my new design;
FIG. 2 is a rear, left and bottom perspective view thereof;
FIG. 3 is a front view thereof;
FIG. 4 is a rear view thereof;
FIG. 5 is a left side view thereof;
FIG. 6 is a right side view thereof;
FIG. 7 is a top plan view thereof;
FIG. 8 is a bottom plan view thereof; and,
FIG. 9 is an enlarged view of portion of FIG. 1 thereof.
The broken lines shown in the drawings illustrate portions of the bird house that form no part of the claimed design.

7. 发明授权

US07902422B2 Regulating the ethylene response of a plant by modulation of F-box proteins 有权
标题翻译：通过调节F盒蛋白来调节植物的乙烯应答
公开(公告)号：US07902422B2
公开(公告)日：2011-03-08
申请号：US12643033
申请日：2009-12-21
申请人： Hongwei Guo , Joseph R. Ecker
发明人： Hongwei Guo , Joseph R. Ecker
IPC分类号： A01H1/00 , A01H5/00 , C12N15/09 , C12N15/82
CPC分类号： C12N15/8291 , C12N15/8249 , C12N15/8261 , C12N15/8266 , C12N15/8267 , C12N15/8271
摘要： The invention relates to transgenic plants having reduced sensitivity to ethylene as a result of having a recombinant nucleic acid encoding an F-box protein that interacts with a EIN3 involved in an ethylene response of plants, and a method of producing a transgenic plant with reduced ethylene sensitivity by transforming the plant with a nucleic acid sequence encoding an F-box protein. The inventions also relates to methods of altering the ethylene response in a plant by modulating the activity or expression of an F-box protein.
摘要翻译：本发明涉及具有降低的对乙烯的敏感性的转基因植物，其具有编码与参与植物乙烯应答的EIN3相互作用的F盒蛋白的重组核酸的结果，以及生产具有还原型乙烯的转基因植物的方法通过用编码F盒蛋白的核酸序列转化植物的灵敏度。本发明还涉及通过调节F盒蛋白的活性或表达来改变植物中的乙烯应答的方法。

8. 发明授权

US07655835B2 Regulating the ethylene response of a plant by modulation of F-box proteins 有权
标题翻译：通过调节F盒蛋白来调节植物的乙烯应答
公开(公告)号：US07655835B2
公开(公告)日：2010-02-02
申请号：US11298286
申请日：2005-12-09
申请人： Hongwei Guo , Joseph R. Ecker
发明人： Hongwei Guo , Joseph R. Ecker
IPC分类号： C12N15/82 , C12N15/09 , A01H1/00
CPC分类号： C12N15/8291 , C12N15/8249 , C12N15/8261 , C12N15/8266 , C12N15/8267 , C12N15/8271
摘要： The invention relates to transgenic plants having reduced sensitivity to ethylene as a result of having a recombinant nucleic acid encoding a F-box protein, and a method of producing a transgenic plant with reduced ethylene sensitivity by transforming the plant with a nucleic acid sequence encoding a F-box protein.
摘要翻译：本发明涉及由于具有编码F盒蛋白的重组核酸而对乙烯具有降低的敏感性的转基因植物，以及通过用编码一个或多个核苷酸序列的核酸序列转化植物来生产具有降低的乙烯敏感性的转基因植物的方法 F盒蛋白。

9. 外观设计

USD1004211S1 Bird house 有权
公开(公告)号：USD1004211S1
公开(公告)日：2023-11-07
申请号：US29888762
申请日：2023-04-04
申请人： Hongwei Guo
设计人： Hongwei Guo
摘要： FIG. 1 is a front, right and top perspective view of a bird house, showing my design.
FIG. 2 is a rear, left and bottom perspective view thereof.
FIG. 3 is a front, right and top perspective view thereof.
FIG. 4 is a front elevation view thereof.
FIG. 5 is a rear elevation view thereof.
FIG. 6 is a left side elevation view thereof.
FIG. 7 is a right side elevation view thereof.
FIG. 8 is a top plan view thereof; and,
FIG. 9 is a bottom plan view thereof.
The broken lines depict portions of the bird house that form no part of the claimed design.

10. 发明申请

US20160138057A1 Methods for enhancing alpha-ketoglutarata production in Yarrowia lipolytica 审中-公开
标题翻译：在解脂耶氏酵母中增强α-酮戊二酸的生产方法
公开(公告)号：US20160138057A1
公开(公告)日：2016-05-19
申请号：US14557468
申请日：2014-12-02
申请人： Jian Chen , Jingwen Zhou , Hongwei Guo , Weizhu Zeng , Guocheng Du
发明人： Jian Chen , Jingwen Zhou , Hongwei Guo , Weizhu Zeng , Guocheng Du
IPC分类号： C12P7/50 , C12N9/06
CPC分类号： C12P7/50 , C12N9/0016 , C12Y104/01002
摘要： The present invention provides methods for enhancing α-KG production in Yarrowia lipolytica, relates to the field of metabolic engineering. This invention successfully overexpresses the glutamate dehydrogenase in wild type strain Y. lipolytica WSH-Z06 to construct the recombinant Y. lipolytica WSH-Z06 which regulates the glutamate catabolism to synthesis α-KG. L-methionine imine is added into the fermentation medium during the process to strengthen the supply of intracellular glutamate and inhibite the intracellular glutamine synthesis from glutamate metabolism and then enhance the accumunation of α-KG. Therefor, the present invention provides an effective method for enhancing the accumunation of α-KG through regulation of intracellular amino acid metabolism.
摘要翻译：本发明提供了在解脂耶氏酵母中增强α-KG生产的方法，涉及代谢工程领域。本发明成功地过表达了野生型脂肪分解杆菌WSH-Z06中的谷氨酸脱氢酶，构建了重组解脂亚罗威阿酵母WSH-Z06，其调节合成α-KG的谷氨酸分解代谢。在加工过程中将L-甲硫氨酸亚胺加入到发酵培养基中，以加强细胞内谷氨酸的供应，并从谷氨酸代谢抑制胞内谷氨酰胺合成，从而增强α-KG的积累。因此，本发明提供了通过调节细胞内氨基酸代谢来增强α-KG的积累的有效方法。

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