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1. 发明授权

US06704601B1 Implantable medical stimulation device having reconfigurable memory 有权
标题翻译：具有可重构存储器的植入式医疗刺激装置
公开(公告)号：US06704601B1
公开(公告)日：2004-03-09
申请号：US09927758
申请日：2001-08-09
申请人： Jorge N. Amely-Velez , Dro Darbidian , Steven W. Badelt
发明人： Jorge N. Amely-Velez , Dro Darbidian , Steven W. Badelt
IPC分类号： A61N108
CPC分类号： G06F9/445 , A61N1/08 , G06F12/0638
摘要： The implantable medical device is provided with typically equal portions of both random access memory (RAM) and read only memory (ROM) and a virtual memory space is defined equal to the amount of memory in one of the memory devices. In a specific example, the RAM and ROM provide 256 K of memory each, with the virtual memory space also set to 256 K. A zone control register is provided which specifies, for each of a set of predetermined zones within the virtual memory space, whether memory access commands are to be routed to RAM or ROM. Control bits within the zone control register may be reset to permit portions of memory to be remapped from one memory device to the other. By providing RAM and ROM each typically equal in size to the virtual memory space, software for use in the device may be tested and debugged using RAM then transferred to ROM for use in production devices. By providing dual RAM and ROM, software upgrades or software bug fixes are easily performed merely by downloading new software into RAM, then resetting the zone control register to point to RAM, rather than ROM. Additionally, when necessary, the overall virtual memory space may be expanded to encompass both the RAM and ROM thereby permitting access to greater quantities of memory.
摘要翻译：可植入医疗装置设置有随机存取存储器（RAM）和只读存储器（ROM）的通常相等的部分，并且将虚拟存储器空间定义为等于存储器件之一中的存储器量。在具体示例中，RAM和ROM提供256K的存储器，虚拟存储器空间也设置为256K。提供了一个区域控制寄存器，其为虚拟存储器空间内的一组预定区域中的每一个指定，存储器访问命令是否被路由到RAM或ROM。区域控制寄存器内的控制位可能被复位，以允许存储器的一部分从一个存储器件重映射到另一个。通过提供大体上与虚拟存储器空间相等的RAM和ROM，可以使用RAM测试和调试用于设备的软件，然后将其转移到ROM以用于生产设备。通过提供双RAM和ROM，只需通过将新软件下载到RAM中即可轻松执行软件升级或软件错误修复，然后将区域控制寄存器重置为指向RAM而不是ROM。另外，当需要时，整个虚拟存储器空间可以被扩展以包含RAM和ROM两者，从而允许访问更大量的存储器。

2. 发明授权

US5720767A Impedance dependent implantable cardioverter-defibrillator 失效
标题翻译：阻抗依赖型植入式心律转复除颤器
公开(公告)号：US5720767A
公开(公告)日：1998-02-24
申请号：US720738
申请日：1996-10-02
申请人： Jorge N. Amely-Velez
发明人： Jorge N. Amely-Velez
IPC分类号： A61N1/39
CPC分类号： A61N1/3937 , A61N1/3931 , A61N1/3912
摘要： An implantable cardiac stimulation device contains a high voltage defibrillating unit. A protection circuit is connected to the defibrillating unit to guard against excessive current during a high voltage discharge. The protection circuit prevents damage to the defibrillation unit and to the associated heart tissue. The defibrillation current is monitored by the protection circuit and if excessive, the defibrillation current is reduced by routing the current through an additional impedance. The protection circuit operates in real-time to remove the additional impedance if the defibrillation current returns to a safe level. A memory device attached to the protection circuit records the event of an excessive defibrillation current.
摘要翻译：可植入心脏刺激装置包含高压去纤颤装置。保护电路连接到除颤单元以防止在高压放电期间的过大电流。保护电路可防止对除颤单元和相关心脏组织的损伤。除颤电流由保护电路监测，如果过多，通过使电流穿过附加阻抗来减小除颤电流。如果除颤电流恢复到安全水平，则保护电路实时工作以去除附加阻抗。连接到保护电路的存储器件记录过度除颤电流的事件。

3. 发明授权

US06553259B2 System and method of performing automatic capture in an implantable cardiac stimulation device 有权
公开(公告)号：US06553259B2
公开(公告)日：2003-04-22
申请号：US09810929
申请日：2001-03-14
申请人： Gabriel A. Mouchawar , Jorge N. Amely-Velez , George I. Isaac , Steven W. Badelt
发明人： Gabriel A. Mouchawar , Jorge N. Amely-Velez , George I. Isaac , Steven W. Badelt
IPC分类号： A61N1362
CPC分类号： A61N1/3712
摘要： An implantable cardiac stimulation device possessing pacing, cardioversion and defibrillation functions and automatic capture capabilities, for automatically verifying capture during stimulation operations and, as necessary, automatically delivering back-up stimulation pulses when capture is lost, and subsequently adjusting the stimulation energy to a level safely above that needed to achieve capture. The stimulation device utilizes a method for maintaining capture by means of a capture search algorithm, so that whenever loss of capture is detected, it re-determines the minimum stimulation energy required to achieve capture. Another aspect of the stimulation device is the automatic threshold testing which is invoked to determine the minimum stimulation pulse energy needed to ensure capture. When the automatic capture function is enabled, the stimulation device initiates a stimulation refractory period, upon the expiration of which, the stimulation device sets a sensing threshold to a predetermined level and then either maintaining this level fixed or causing it to decay, during an alert interval. Concurrently, the stimulation device verifies capture during the alert interval.

4. 发明授权

US06400985B1 Method and apparatus for timing events within an implantable medical device 有权
公开(公告)号：US06400985B1
公开(公告)日：2002-06-04
申请号：US09777646
申请日：2001-02-06
申请人： Jorge N. Amely-Velez
发明人： Jorge N. Amely-Velez
IPC分类号： A61N137
CPC分类号： A61N1/37 , A61N1/362
摘要： A technique is described for timing hardware or software events for use in an implantable medical device capable of performing many concurrent processes. The technique exploits a first timer for timing events using a timing interval of one millisecond and a second timer or clock signal for timing events using a timing interval of two seconds. A receive unit receives timer requests from the many concurrent processes with each timer request specifying a time delay before an interrupt or other timer completion signal is required. A control unit uses either the first timer or the second timer to time the request based upon the time delay and the respective timing intervals. An interrupt or other timer completion signal is issued to the requesting device following the specified time delay as timed by the selected timer. For the purposes of prioritizing two or more timer requests to be timed by the same timer, the device also exploits the concept of a pseudo clock for tracking time up to a maximum pre-determined period of time of, for example, 65 seconds.

5. 发明申请

US20130131759A1 SHIELDING TELEMETRY COMMUNCIATIONS BETWEEN ACTIVE IMPLANTABLE MEDICAL DEVICES AND EXTERNAL INSTRUMENTS FROM HIGH POWER ELECTRICAL INTERFERERS 有权
标题翻译：有源可植入医疗器械与大功率电子干扰器的外部仪器之间的屏蔽电话通讯
公开(公告)号：US20130131759A1
公开(公告)日：2013-05-23
申请号：US13303715
申请日：2011-11-23
申请人： Jorge N. Amely-Velez , Armando M. Cappa , J. Terry Benson , Robel Borja , Allan R. Schwartz , Anthony Li
发明人： Jorge N. Amely-Velez , Armando M. Cappa , J. Terry Benson , Robel Borja , Allan R. Schwartz , Anthony Li
IPC分类号： A61N1/36
CPC分类号： A61N1/37223 , A61N1/16 , A61N1/37229
摘要： Disclosed herein is a shield for shielding a telemetry wand from electromagnetical interference capable of interfering with telemetry communications between the telemetry wand and an AIMD in a patient. The telemetry wand may include a first side that is configured to be placed against a patient, a second side generally opposite the first side, a lateral side between the first and second sides, a hole extending between the first and second sides, and a cable extending from the lateral side. The shield may include a shell including a wall that defines a volume and an opening in the shell. The volume may be configured to receive therein the telemetry wand such that the second and lateral sides of the telemetry wand face respective portions of the wall and the first side faces the opening in the shell.
摘要翻译：本文公开了一种用于屏蔽遥测魔杖免受电磁干扰的屏蔽，能够干扰遥测棒与患者中的AIMD之间的遥测通信。遥测棒可以包括构造成抵靠患者放置的第一侧，大致与第一侧相对的第二侧，第一和第二侧之间的横向侧，在第一和第二侧之间延伸的孔，以及电缆从侧面延伸。护罩可以包括壳体，其包括限定容积的壁和壳中的开口。体积可以被配置为在其中接收遥测棒，使得遥测棒的第二侧面和侧面面对壁的相应部分，并且第一侧面向壳体中的开口。

6. 发明授权

US07065403B1 System and method for measuring lead impedance in an implantable stimulation device employing pulse-train waveforms 失效
标题翻译：用于测量采用脉冲波形的可植入刺激装置中的引线阻抗的系统和方法
公开(公告)号：US07065403B1
公开(公告)日：2006-06-20
申请号：US10306502
申请日：2002-11-26
申请人： Gabriel A. Mouchawar , Jorge N. Amely-Velez , Steven W. Badelt
发明人： Gabriel A. Mouchawar , Jorge N. Amely-Velez , Steven W. Badelt
IPC分类号： A61N1/36
CPC分类号： A61N1/3931 , A61N2001/083
摘要： A leakage detection system for use in an implantable cardiac stimulation device, such as a cardioverter defibrillator. The leakage detection system includes a switch bank and a controller that regulates the switching arrangements of various switches. The leakage detection system causes pulse generators to generate a pulse-train waveform comprised of a sequence of pulses of opposite polarities, and to deliver these pulses in a preselected temporal relation. The controller detects the current leakage from the pulse generator to the tissues by sensing and analyzing the voltage or current of the pulse generator, leads, and electrodes. The pulsatility and alternating polarities of biphasic pulse-train waveforms increase the stimulation threshold of the motor or sensory nerves and excitable tissues.
摘要翻译：一种用于可植入心脏刺激装置（例如心律转复除颤器）的泄漏检测系统。泄漏检测系统包括开关组和调节各种开关的开关装置的控制器。泄漏检测系统使得脉冲发生器产生由相反极性的脉冲序列组成的脉冲串波形，并将这些脉冲递送到预选的时间关系。控制器通过感测和分析脉冲发生器，引线和电极的电压或电流来检测从脉冲发生器到组织的电流泄漏。双相脉冲串波形的脉动和交替极性增加了马达或感觉神经和可兴奋组织的刺激阈值。

7. 发明授权

US06636765B2 Method and apparatus for timing events within an implantable medical device 失效
公开(公告)号：US06636765B2
公开(公告)日：2003-10-21
申请号：US09777649
申请日：2001-02-06
申请人： Jorge N. Amely-Velez
发明人： Jorge N. Amely-Velez
IPC分类号： A61N118
CPC分类号： A61N1/362 , A61N1/3956
摘要： A technique is described for timing hardware or software events for use in an implantable medical device capable of performing many concurrent processes. The technique exploits a first timer for timing events using a timing interval of one millisecond and a second timer or clock signal for timing events using a timing interval of two seconds. A receive unit receives timer requests from the many concurrent processes with each timer request specifying a time delay before an interrupt or other timer completion signal is required. A control unit uses either the first timer or the second timer to time the request based upon the time delay and the respective timing intervals. An interrupt or other timer completion signal is issued to the requesting device following the specified time delay as timed by the selected timer. For the purposes of prioritizing two or more timer requests to be timed by the same timer, the device also exploits the concept of a pseudo clock for tracking time up to a maximum pre-determined period of time of, for example, 65 seconds.

8. 发明授权

US08527060B2 Shielding telemetry communications between active implantable medical devices and external instruments from high power electrical interferers 有权
标题翻译：屏蔽来自高功率电气干扰源的有源可植入医疗设备和外部仪器之间的遥测通信
公开(公告)号：US08527060B2
公开(公告)日：2013-09-03
申请号：US13303715
申请日：2011-11-23
申请人： Jorge N. Amely-Velez , Armando M. Cappa , J. Terry Benson , Robel Borja , Allan R. Schwartz , Anthony Li
发明人： Jorge N. Amely-Velez , Armando M. Cappa , J. Terry Benson , Robel Borja , Allan R. Schwartz , Anthony Li
IPC分类号： A61N1/36
CPC分类号： A61N1/37223 , A61N1/16 , A61N1/37229
摘要： Disclosed herein is a shield for shielding a telemetry wand from electromagnetical interference capable of interfering with telemetry communications between the telemetry wand and an AIMD in a patient. The telemetry wand may include a first side that is configured to be placed against a patient, a second side generally opposite the first side, a lateral side between the first and second sides, a hole extending between the first and second sides, and a cable extending from the lateral side. The shield may include a shell including a wall that defines a volume and an opening in the shell. The volume may be configured to receive therein the telemetry wand such that the second and lateral sides of the telemetry wand face respective portions of the wall and the first side faces the opening in the shell.
摘要翻译：本文公开了一种用于屏蔽遥测魔杖免受电磁干扰的屏蔽，能够干扰遥测棒与患者中的AIMD之间的遥测通信。遥测棒可以包括构造成抵靠患者放置的第一侧，大致与第一侧相对的第二侧，第一和第二侧之间的横向侧，在第一和第二侧之间延伸的孔，以及电缆从侧面延伸。护罩可以包括壳体，其包括限定容积的壁和壳中的开口。体积可以被配置为在其中接收遥测棒，使得遥测棒的第二侧面和侧面面对壁的相应部分，并且第一侧面向壳体中的开口。

9. 发明授权

US06937894B1 Method of recharging battery for an implantable medical device 失效
标题翻译：为可植入医疗器械充电电池的方法
公开(公告)号：US06937894B1
公开(公告)日：2005-08-30
申请号：US10045844
申请日：2001-11-08
申请人： George I. Isaac , Jorge N. Amely-Velez , Gabriel A. Mouchawar
发明人： George I. Isaac , Jorge N. Amely-Velez , Gabriel A. Mouchawar
IPC分类号： A61N1/378
CPC分类号： A61N1/3787
摘要： A method of operating an implantable medical device containing a Lithium Silver Vanadium Oxide battery. In response to a detected need for therapy, a current flow is delivered from the battery to a charge storage device. After the battery is at least partly depleted by one or more such deliveries of current or other power consumption, the battery is recharged. The recharging may be initiated in response to a selected time threshold, a selected number of current flow delivery events, a selected voltage level, an excess charge time duration, or other operating characteristics. A limited number of recharging cycles may be provided if the charging is done under controlled conditions with respect to charge current and voltage.
摘要翻译：一种操作含有锂银氧化钒电池的可植入医疗装置的方法。响应于检测到的治疗需要，电流从电池传送到电荷存储装置。在电池至少部分耗尽当前或其他功率消耗的一个或多个这样的传送之后，电池被再充电。可以响应于所选择的时间阈值，所选数量的当前流量递送事件，所选择的电压电平，超量充电时间持续时间或其他操作特性来启动充电。如果在相对于充电电流和电压的受控条件下进行充电，则可以提供有限数量的充电循环。

10. 发明授权

US06535765B1 Implantable medical stimulation device having reconfigurable memory 有权
标题翻译：具有可重构存储器的植入式医疗刺激装置
公开(公告)号：US06535765B1
公开(公告)日：2003-03-18
申请号：US09877623
申请日：2001-06-08
申请人： Jorge N. Amely-Velez , Dro Darbidian , Steven W. Badelt
发明人： Jorge N. Amely-Velez , Dro Darbidian , Steven W. Badelt
IPC分类号： A61N102
CPC分类号： A61N1/37264 , A61N1/37211 , G06F12/0638
摘要： The implantable medical device is provided with typically equal portions of both random access memory (RAM) and read only memory (ROM) and a virtual memory space is defined equal to the amount of memory in one of the memory devices. In a specific example, the RAM and ROM provide 256K of memory each, with the virtual memory space also set to 256K. A zone control register is provided which specifies, for each of a set of predetermined zones within the virtual memory space, whether memory access commands are to be routed to RAM or ROM. Control bits within the zone control register may be reset to permit portions of memory to be remapped from one memory device to the other. By providing RAM and ROM each typically equal in size to the virtual memory space, software for use in the device may be tested and debugged using RAM then transferred to ROM for use in production devices. By providing dual RAM and ROM, software upgrades or software bug fixes are easily performed merely by downloading new software into RAM, then resetting the zone control register to point to RAM, rather than ROM. Additionally, when necessary, the overall virtual memory space may be expanded to encompass both the RAM and ROM thereby permitting access to greater quantities of memory.
摘要翻译：可植入医疗装置设置有随机存取存储器（RAM）和只读存储器（ROM）的通常相等的部分，并且将虚拟存储器空间定义为等于存储器件之一中的存储器量。在一个具体的例子中，RAM和ROM提供256K的内存，虚拟内存空间也设置为256K。提供一个区域控制寄存器，为虚拟存储器空间内的一组预定区域中的每一个指定存储器访问命令是否被路由到RAM或ROM。区域控制寄存器内的控制位可能被复位，以允许存储器的一部分从一个存储器件重映射到另一个。通过提供大体上与虚拟存储器空间相等的RAM和ROM，可以使用RAM测试和调试用于设备的软件，然后将其转移到ROM以用于生产设备。通过提供双RAM和ROM，只需通过将新软件下载到RAM中即可轻松执行软件升级或软件错误修复，然后将区域控制寄存器重置为指向RAM而不是ROM。另外，当需要时，整个虚拟存储器空间可以被扩展以包含RAM和ROM两者，从而允许访问更大量的存储器。

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