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    • 3. 发明申请
    • DEVICE FOR MEASURING PROTEINS USING BIOSENSOR
    • 使用生物传感器测量蛋白质的装置
    • US20110123399A1
    • 2011-05-26
    • US13003998
    • 2009-05-13
    • Hakhyun NamSu-Moon ParkJin-Young ParkJoo Young Cho
    • Hakhyun NamSu-Moon ParkJin-Young ParkJoo Young Cho
    • B01J19/00
    • G01N27/02G01N27/3276G01N33/5438
    • A sensor for measuring a protein with a measurement speed improved from a conventional impedance measurement, using a biosensor is provided. The sensor is capable of efficiently and accurately measuring impedance generated by a selective binding to the protein by Fourier-transforming an electric current signal which is obtained by applying a potential signal of a delta function waveform.The device for measuring a protein using a biosensor includes the biosensor including a sample inlet through which a sample is drawn in, a working electrode on which a receptor layer is coated for selective binding to the specific protein in the drawn sample, and a measuring unit including a reference electrode to form a potential difference with the working electrode, a function generator which applies a potential signal in the form of delta function to the working electrode and the reference electrode, and a data processing unit which measures impedance of the working electrode by Fourier-transforming an electric current obtained in response to the delta function waveform.Accordingly, with the device for measuring a protein using a biosensor is capable of measuring concentration of the protein with accuracy, measurement time is shortened and the concentration of protein can be accurately measured by removing the influence of dispersion.
    • 提供了一种使用生物传感器从传统阻抗测量中测量具有测量速度的蛋白质传感器。 该传感器能够通过对通过应用增量函数波形的电位信号获得的电流信号进行傅立叶变换来有效且准确地测量通过与蛋白质的选择性结合产生的阻抗。 用于使用生物传感器测量蛋白质的装置包括:生物传感器,其包括样品入口,样品通过其吸入;在其上涂覆受体层的工作电极,用于选择性地结合拉伸样品中的特定蛋白质;以及测量单元 包括与工作电极形成电位差的参考电极,将函数发生器以delta函数的形式施加到工作电极和参考电极,以及数据处理单元,其通过以下步骤测量工作电极的阻抗: 傅里叶变换响应于Δ函数波形而获得的电流。 因此,使用生物传感器测定蛋白质的装置能够准确地测定蛋白质的浓度,因此缩短了测定时间,能够通过去除分散的影响来精确地测定蛋白质的浓度。