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1. 发明授权

US06936056B2 Intravascular system for occluded blood vessels and guidewire for use therein 失效
公开(公告)号：US06936056B2
公开(公告)日：2005-08-30
申请号：US10355754
申请日：2003-01-31
申请人： John E. Nash , William T. Fisher , Charles W. Dodson, Jr. , John Michael Henderson , Joseph W. Kaufmann
发明人： John E. Nash , William T. Fisher , Charles W. Dodson, Jr. , John Michael Henderson , Joseph W. Kaufmann
IPC分类号： A61B17/00 , A61B17/22 , A61B17/32 , A61D1/02 , A61M1/00 , A61M31/00
CPC分类号： A61B17/320758 , A61B2017/00845 , A61B2017/00853 , A61B2017/22038 , A61B2217/005 , A61B2217/007 , A61M1/0058
摘要： A system and method for opening a lumen in an occluded blood vessel, e.g., a coronary bypass graft, of a living being. The system comprises an atherectomy catheter having a working head, e.g., a rotary impacting impeller, and a debris extraction sub-system. The atherectomy catheter is located within a guide catheter. The working head is arranged to operate on, e.g., impact, the occlusive material in the occluded vessel to open a lumen therein, whereupon some debris may be produced. The debris extraction sub-system introduces an infusate liquid at a first flow rate adjacent the working head and withdraws that liquid and some blood at a second and higher flow rate, through the guide catheter to create a differential flow adjacent the working head, whereupon the debris is withdrawn in the infusate liquid and blood for collection outside the being's body. The introduction of the infusate liquid may also be used to establish an unbalanced flow adjacent the working head to enable the atherectomy catheter to be steered hydrodynamically. A guide wire having an inflatable balloon on its distal end may be used with the atherectomy catheter to block the flow of debris distally, while enabling distal tissues to be perfused with an oxygenating liquid. At least one flow control port may be provided in the guide catheter to prevent collapse of the vessel being revascularized. A cradle is provided to fix the guide catheter and guide wire in position within the body of the being while enabling the atherectomy catheter to be advanced along the guide wire and through the guide catheter. The guide catheter includes a wear resistant coating and is constructed so that its distal end includes plural sections of different outside diameters, with the distal most section being of the smallest outside diameter. A control console is provided to establish various modes of operation of the system based on manual inputs via switches or voice commands via voice recognition circuitry. A video panel displays the various modes of operation and instructions to the operator.

2. 发明授权

US06652546B1 System and method of use for revascularizing stenotic bypass grafts and other occluded blood vessels 有权
公开(公告)号：US06652546B1
公开(公告)日：2003-11-25
申请号：US09690976
申请日：2000-10-18
申请人： John E. Nash , William T. Fisher , Charles W. Dodson, Jr. , John Michael Henderson , Joseph W. Kaufmann
发明人： John E. Nash , William T. Fisher , Charles W. Dodson, Jr. , John Michael Henderson , Joseph W. Kaufmann
IPC分类号： A61D102
CPC分类号： A61B17/320758 , A61B2017/00845 , A61B2017/00853 , A61B2017/22038 , A61B2217/005 , A61B2217/007 , A61M1/0058
摘要： A system and method for opening a lumen in an occluded blood vessel, e.g., a coronary bypass graft, of a living being. The system comprises an atherectomy catheter having a working head, e.g., a rotary impacting impeller, and a debris extraction sub-system. The atherectomy catheter is located within a guide catheter. The working head is arranged to operate on, e.g., impact, the occlusive material in the occluded vessel to open a lumen therein, whereupon some debris may be produced. The debris extraction sub-system introduces an infusate liquid at a first flow rate adjacent the working head and withdraws that liquid and some blood at a second and higher flow rate, through the guide catheter to create a differential flow adjacent the working head, whereupon the debris is withdrawn in the infusate liquid and blood for collection outside the being's body. The introduction of the infusate liquid may also be used to establish an unbalanced flow adjacent the working head to enable the atherectomy catheter to be steered hydrodynamically. A guide wire having an inflatable balloon on its distal end may be used with the atherectomy catheter to block the flow of debris distally, while enabling distal tissues to be perfused with an oxygenating liquid. At least one flow control port may be provided in the guide catheter to prevent collapse of the vessel being revascularized. A cradle is provided to fix the guide catheter and guide wire in position within the body of the being while enabling the atherectomy catheter to be advanced along the guide wire and through the guide catheter. The guide catheter includes a wear resistant coating and is constructed so that its distal end includes plural sections of different outside diameters, with the distal most section being of the smallest outside diameter. A control console is provided to establish various modes of operation of the system based on manual inputs via switches or voice commands via voice recognition circuitry. A video panel displays the various modes of operation and instructions to the operator.

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