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    • 3. 发明授权
    • Polyfunctional catalysts
    • 多官能催化剂
    • US4157316A
    • 1979-06-05
    • US833922
    • 1977-09-16
    • Charles E. ThompsonJohn J. MooneyCarl D. KeithWilliam A. Mannion
    • Charles E. ThompsonJohn J. MooneyCarl D. KeithWilliam A. Mannion
    • B01D53/94B01J23/56B01J23/60B01J23/64B01J23/652B01J23/656B01J23/89B01J37/02B01J21/04B01J23/10B01J23/74
    • B01D53/945B01J23/56B01J23/89B01J37/0238Y02T10/22
    • This invention provides polyfunctional catalysts comprising a composite of platinum and one or more of rhodium, ruthenium and iridium, a substantially larger quantity of one or more base metal oxides in which the metal is selected from the group consisting of metals having an atomic number from 25 to 28 and rhenium, and an alumina support, which composite is made and then deposited on a suitable carrier. In a preferred embodiment, the catalysts contain 1-20 weight percent of said base metal oxide, typically nickel oxide; 0.05-0.5 weight percent platinum; and 0.002-0.3 weight percent rhodium, and an alumina support deposited on a monolith or other carrier. The improved catalysts are especially applicable for purifying exhaust gases from combustion processes, and in particular those from internal combustion engines.These polyfunctional catalysts have in a single formulation, the ability to accomplish four objectives - to oxidize carbon monoxide and unburned hydrocarbons while reducing nitrogen oxides, thereby converting those contaminants found in the exhaust of internal combustion engines into carbon dioxide, water and elemental nitrogen, but without producing significant amounts of hydrogen sulfide, sulfur trioxide or sulfuric acid. Such chemical conversions take place over the catalyst when the ratio of air to fuel supplied to the catalyst is controlled to nearly stoichiometric conditions, thereby maintaining the exhaust feed gases within a narrow compositional range, sometimes called a "window," in which the catalyst can substantially convert the contaminants.
    • 本发明提供了包含铂和铑,钌和铱中的一种或多种的复合物的多官能催化剂,其中大量的一种或多种贱金属氧化物,其中金属选自原子序数为25的金属 至28和铼,以及氧化铝载体,该复合材料制成然后沉积在合适的载体上。 在优选的实施方案中,催化剂含有1-20重量%的所述贱金属氧化物,通常为氧化镍; 0.05-0.5重量百分比的铂; 和0.002-0.3重量%的铑,以及沉积在整料或其它载体上的氧化铝载体。 改进的催化剂特别适用于净化来自燃烧过程的废气,特别是来自内燃机的废气。
    • 7. 发明授权
    • Antidepressant effect of norepinephrine uptake 2 inhibitors and combined medications including them
    • 去甲肾上腺素摄取2抑制剂和联合用药包括它们的抗抑郁作用
    • US06403645B2
    • 2002-06-11
    • US09811235
    • 2001-03-16
    • Joseph J. SchildkrautJohn J. Mooney
    • Joseph J. SchildkrautJohn J. Mooney
    • A61K31195
    • A61K31/4178A61K31/198A61K31/5513A61K45/06A61K2300/00
    • Norepinephrine uptake 2 inhibitors (or their precursors) are administered to enhance the effect of norepinephrine reuptake inhibitors and other antidepressants. The uptake 2 inhibitor may be combined in a single medication with a norepinephrine reuptake inhibitor, such as imipramine, desipramine, or reboxetine, in order to inhibit both uptake mechanisms. The norepinephrine uptake 2 inhibitors may also be combined with MAO inhibitors or with selective serotonin reuptake inhibitors. Alternatively, the norepinephrine uptake 2 inhibitors may be useful antidepressants in their own right, without the need for co-administration of other antidepressants. One class of norepinephrine uptake 2 inhibitors is normetanephrine (the O-methylated metabolite of norepinephrine) and normetanephrine precursors [such as 3(4-hydroxy-3-methoxyphenyl)-serine (4H-3MePS ), particularly L-threo-3-(4-H-3 MePS)] that are transported to the brain where they are converted into normetanephrine, thereby enhancing the effect of other antidepressants. For example, the invention enhances the antidepressant effect of norepinephrine reuptake inhibitors.
    • 施用去甲肾上腺素摄取2抑制剂(或其前体)以增强去甲肾上腺素再摄取抑制剂和其它抗抑郁药的作用。 摄取2抑制剂可以组合在单一药物中与去甲肾上腺素再摄取抑制剂如丙米嗪,地昔帕明或瑞波西汀,以抑制两种摄取机制。 去甲肾上腺素摄取2抑制剂也可以与MAO抑制剂或选择性5-羟色胺再摄取抑制剂组合。 或者,去甲肾上腺素摄取2抑制剂本身可以是有用的抗抑郁药,而不需要共同给予其它抗抑郁药。 一类去甲肾上腺素摄取2抑制剂是正丙肾上腺素(去甲肾上腺素的O-甲基化代谢物)和正丙肾上腺素前体[例如3(4-羟基-3-甲氧基苯基) - 丝氨酸(4H-3MePS),特别是L-苏式-3- 4-H-3 MePS)],其被转运到脑中,在那里它们被转化成正丙肾上腺素,从而增强其他抗抑郁药的作用。 例如,本发明增强了去甲肾上腺素再摄取抑制剂的抗抑郁作用。
    • 9. 发明授权
    • Polyfunctional catalysts and method of use
    • 多官能催化剂及其使用方法
    • US4552733A
    • 1985-11-12
    • US682978
    • 1984-12-18
    • Charles E. ThompsonJohn J. MooneyCarl D. KeithWilliam A. Mannion
    • Charles E. ThompsonJohn J. MooneyCarl D. KeithWilliam A. Mannion
    • B01D53/94B01J23/56B01J23/89B01J37/02B01D53/00B01J8/02
    • B01D53/945B01J23/56B01J23/89B01J37/0238Y02T10/22
    • This invention provides polyfunctional catalysts comprising a composite of platinum and one or more of rhodium, ruthenium and iridium, a substantially larger quantity of one or more base metal oxides in which the metal is selected from the group consisting of metals having an atomic number from 25 to 28 and rhenium, and an alumina support, which composite is made and then deposited on a suitable carrier. In a preferred embodiment, the catalysts contain 1-20 weight percent of said base metal oxide, typically nickel oxide; 0.05-0.5 weight percent platinum; and 0.002-0.3 weight percent rhodium, and an alumina support deposited on a monolith or other carrier. The improved catalysts are especially applicable for purifying exhaust gases from combustion processes, and in particular those from internal combustion engines.These polyfunctional catalysts have in a single formulation, the ability to accomplish four objectives--to oxidize carbon monoxide and unburned hydrocarbons while reducing nitrogen oxides, thereby converting those contaminants found in the exhaust of internal combustion engines into carbon dioxide, water and elemental nitrogen, but without producing significant amounts of hydrogen sulfide, sulfur trioxide or sulfuric acid. Such chemical conversions take place over the catalyst when the ratio of air to fuel supplied to the catalyst is controlled to nearly stoichiometric conditions, thereby maintaining the exhaust feed gases within a narrow compositional range, sometimes called a "window", in which the catalyst can substantially convert the contaminants.
    • 本发明提供了包含铂和铑,钌和铱中的一种或多种的复合物的多官能催化剂,其中大量的一种或多种贱金属氧化物,其中金属选自原子序数为25的金属 至28和铼,以及氧化铝载体,该复合材料制成然后沉积在合适的载体上。 在优选的实施方案中,催化剂含有1-20重量%的所述贱金属氧化物,通常为氧化镍; 0.05-0.5重量百分比的铂; 和0.002-0.3重量%的铑,以及沉积在整料或其它载体上的氧化铝载体。 改进的催化剂特别适用于净化来自燃烧过程的废气,特别是来自内燃机的废气。 这些多官能催化剂在单一配方中具有实现四个目标的能力 - 在减少氮氧化物的同时氧化一氧化碳和未燃烧的烃,从而将内燃机排气中发现的污染物转化为二氧化碳,水和元素氮,但是 而不产生显着量的硫化氢,三氧化硫或硫酸。 当提供给催化剂的空气与燃料的比例被控制到接近化学计量条件时,这种化学转化发生在催化剂上,从而将排气进料气体保持在窄的组成范围内,有时被称为“窗口”,其中催化剂可以 基本上转化污染物。
    • 10. 发明授权
    • Oxygen sensor control system
    • 氧传感器控制系统
    • US4202301A
    • 1980-05-13
    • US829555
    • 1977-08-31
    • Jack EarlyJohn J. MooneyCarl D. Keith
    • Jack EarlyJohn J. MooneyCarl D. Keith
    • F02D41/34F02D41/14F02D3/00
    • F02D41/1495F02D41/1474F02D41/148
    • An air-to-fuel ratio control mechanism in an internal combustion engine operates in partial response to the output of a control circuit, which circuit in turn is responsive to the output of an oxygen sensor mounted in the exhaust of the engine. The control circuit biases the control mechanism toward a predetermined desired air-to-fuel ratio, normally at or near stoichiometric. When the sensor output deviates above a first predetermined value or below a second predetermined value for longer than a predetermined time period, a comparator circuit provides a disabling signal which disconnects the control circuit from the air-to-fuel ratio control mechanism. At the same time, the disabling signal connects a predetermined signal to the air-to-fuel ratio control mechanism. This predetermined signal simulates a nominal control circuit output to maintain the air-to-fuel ratio close to stoichiometric or some other preferred setting such as a air/fuel ratio which is lean. An indicator is turned on by the disabling signal to alert the operator to possible malfunction.
    • 内燃机中的空燃比控制机构部分响应于控制电路的输出而工作,该控制电路又响应于安装在发动机排气中的氧传感器的输出。 控制电路将控制机构偏向预定的期望的空气 - 燃料比,通常在或接近化学计量。 当传感器输出偏离高于第一预定值或低于第二预定值长于预定时间段时,比较器电路提供将控制电路与空燃比控制机构断开的禁用信号。 同时,禁用信号将预定信号连接到空燃比控制机构。 该预定信号模拟标称控制电路输出以维持空气 - 燃料比接近化学计量或一些其它优选的设置,例如稀薄的空气/燃料比。 通过禁用信号打开指示灯,提醒操作员可能发生故障。