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1. 发明专利

GB363778A Improvements relating to change speed operating mechanism for motor cycles and the like 未知
公开(公告)号：GB363778A
公开(公告)日：1931-12-31
申请号：GB3348330
申请日：1930-11-07
申请人： JOHN CLIFFORD HARRIS
IPC分类号： B62M25/04
摘要： 363,778. Controlling variable-speed gearing. HARRIS, J. C., 20, Amesbury Road, Moseley, Birmingham. Nov. 7, 1930, No. 33483. [Class 80 (ii).] In order to impart stepped angular displacements in either direction to a spindle A, Fig. 1, controlling the change-speed gear of a motor cycle, repeated oscillations are imparted to a pedal N, Fig. 5. The pedal N is secured to a cover-plate M loose on the spindle A, and is struck by the foot to effect the required movement. A peg L fast in the plate M passes to the left of Fig. 1 through a notch J, Fig. 4, in a pawl plate G, then through a gap X, Fig. 3, in a stop plate E, then over a fixed angled stop C between two springs D , D , Fig. 2, supported in a fixed casing B. Stop plate E, Fig. 3A, carries a through peg F on one end Fl of which is pivoted the pawl plate G which can rock to bring either of its pawl teeth H , H , Fig. 4, into engagement with a ratchet wheel K. Fig. 3, which it embraces. Ratchet wheel K is fast on spindle A. The other end of peg F projects over a fixed angled stop C , Fig. 2, between two fixed return springs D3, D4. When the pedal N is moved up or down, the cover-plate M turns so that the peg L carries pawl plate G with it without at first moving the stop plate E. Plate G rocks far enough to engage one or other of the pawl teeth H , H with the ratchet wheel K. The plates M, G, and E, ratchet wheel K, and spindle A are then locked together and are carried along with the pedal until one of two stop pegs S , S2, Fig. 3, on the plate E engages and is stopped at R, R , Fig. 2. Spindle A has completed one step in the gear change, and is locked by suitable means so that on release of the pedal N, the springs DI and D or D and D3 return the other parts to the initial position. Spindle A may be moved a step farther, or a step back, by a further oscillation of the pedal. An indicator P, Fig. 1, fast to the spindle A moves over the fixed casing B to show what gear is connected at any time. The spindle A may be moved directly at any time by an independent hand-lever Q.

2. 发明专利

GB140600A Improvements in starting devices in gear boxes on motor cycles 未知
公开(公告)号：GB140600A
公开(公告)日：1920-04-01
申请号：GB811919
申请日：1919-04-01
申请人： JOHN CLIFFORD HARRIS
IPC分类号： F02N3/04
摘要： 140,600. Harris, J. C. April 1, 1919. No Patent granted (Sealing fee not paid). Turning-gear.- A kick-starter for application to the variable-speed gear of a motor - cycle comprises a pinion b loose on the shaft d of the starting-pedal f and driven from a ratchet-toothed disk g sliding on the shaft d. The pinion b gears with a pinion a on the main shaft of the gear, connected to the engine shaft through chain gear and a clutch. According to the invention. the disk g has two short slots engaged by spring plungers m. carried by the casing, and is normally held out of engagement with the pinion b by a light spring j. When the pedal f is depressed, the slots leave the plungers m, which force the disk into engagement with the pinion. At the end of the stroke, the slots register again with the plungers, and the disk is disengaged by the spring j.

3. 发明专利

GB330164A Improvements in variable speed gear for use in the power-transmission systems of motor-cycles and other vehicles 未知
公开(公告)号：GB330164A
公开(公告)日：1930-06-05
申请号：GB2077429
申请日：1929-07-06
申请人： JOHN CLIFFORD HARRIS
IPC分类号： B62M25/00
摘要： 330,164. Harris, J. C. July 6, 1929. Variable-speed gearing comprises three clutch and gear elements shiftable together to change speed, one of these e being on the main shaft, the others f, g being relatively rotatable and loose on a lay shaft 2. The main shaft comprises an inner driving-shaft 1 and an outer driven sleeve 3. The shaft 1 constantly drives the gear train b, c, d, a and the countershaft, gear a being loose on sleeve 3. The double gear element e is splined on sleeve 3, and when it is moved to its extreme positions so that its clutch ends e , e engage clutch elements b , a on the gears b, a, respectively, the first or highest and the fourth or lowest speeds are produced. The second and third speeds are effected respectively when the unit e, f, g is moved so that the gear g engages clutch dogs k on shaft 2 and so that the gear f engages clutch dogs k. The elements e, f, g are held together by a yoke 5 operated by a pivoted striking-fork 11.

4. 发明授权

US07557110B2 Pyrazolo[1,5-A] pyrimidine derivatives 失效
标题翻译：吡唑并[1,5-A]嘧啶衍生物
公开(公告)号：US07557110B2
公开(公告)日：2009-07-07
申请号：US10547080
申请日：2004-03-01
申请人： Kenichiro Kataoka , Naotaka Suzuki , Tomomi Kosugi , Minoru Imai , Hiroaki Makino , Mika Takakuwa , Gen Unoki , Aiko Fujino , Yasuhiro Oue , Yuko Yamakoshi , Satoshi Sugiura , Robert Dale Mitchell , James Donald Simpson , John Clifford Harris , Joelle Le
发明人： Kenichiro Kataoka , Naotaka Suzuki , Tomomi Kosugi , Minoru Imai , Hiroaki Makino , Mika Takakuwa , Gen Unoki , Aiko Fujino , Yasuhiro Oue , Yuko Yamakoshi , Satoshi Sugiura , Robert Dale Mitchell , James Donald Simpson , John Clifford Harris , Joelle Le
IPC分类号： C07D487/04 , A61K31/519
CPC分类号： C07D487/04
摘要： The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent kinase inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for a protein kinase mediated disorder in which kinase is implicated, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.
摘要翻译：由式I表示的吡唑并[1,5-a]嘧啶衍生物及其药学上可接受的盐表现出优异的激酶抑制活性。因此，包含化合物作为有效成分的药物预期可用作其中涉及激酶的蛋白激酶介导的病症的治疗或预防剂，例如炎性疾病，自身免疫疾病，破坏性骨病，癌症和/或肿瘤生长。

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