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1. 发明申请

US20100113736A1 INTEGRATED STEAM HEATING IN POLYESTER PRODUCTION PROCESS 有权
标题翻译：聚酯生产过程中的一体化蒸汽加热
公开(公告)号：US20100113736A1
公开(公告)日：2010-05-06
申请号：US12558003
申请日：2009-09-11
申请人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
发明人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
IPC分类号： C08G63/127
CPC分类号： C08G63/78 , Y02P20/125
摘要： Integrated processes for making polyesters are disclosed, that include the steps of: (a) producing an aromatic polycarboxylic acid in a monomer production facility; (b) producing a polyester in a polyester production facility, wherein the producing of the polyester comprises the substeps of: (i) forming a polyester reaction medium comprising at least a portion of the aromatic polycarboxylic acid from the monomer production facility, (ii) subjecting at least a portion of the polyester reaction medium to one or more chemical reactions to thereby produce the polyester, (iii) heating the polyester reaction medium at one or more locations in the polyester production facility via indirect heat exchange with high-pressure steam, wherein the heating causes at least a portion of the high-pressure steam to condense and thereby provide pressurized condensed water, and (iv) flashing at least a portion of the pressurized condensed water to thereby produce lower-pressure steam; and (c) using at least a portion of the lower-pressure steam to provide thermal energy to the monomer production facility.
摘要翻译：公开了制造聚酯的综合方法，包括以下步骤：（a）在单体生产设备中制备芳族多元羧酸; （b）在聚酯制造设备中制造聚酯，其中聚酯的制造包括以下子步骤：（i）从单体生产设备形成包含至少一部分芳族多元羧酸的聚酯反应介质，（ii）使聚酯反应介质的至少一部分进行一个或多个化学反应从而生产聚酯，（iii）通过与高压蒸汽的间接热交换在聚酯生产设备中的一个或多个位置处加热聚酯反应介质，其中所述加热使得所述高压蒸汽的至少一部分冷凝，从而提供加压的冷凝水，和（iv）使加压冷凝水的至少一部分闪蒸，从而产生低压蒸汽; 和（c）使用至少一部分低压蒸汽来向单体生产设备提供热能。

2. 发明授权

US07557110B2 Pyrazolo[1,5-A] pyrimidine derivatives 失效
标题翻译：吡唑并[1,5-A]嘧啶衍生物
公开(公告)号：US07557110B2
公开(公告)日：2009-07-07
申请号：US10547080
申请日：2004-03-01
申请人： Kenichiro Kataoka , Naotaka Suzuki , Tomomi Kosugi , Minoru Imai , Hiroaki Makino , Mika Takakuwa , Gen Unoki , Aiko Fujino , Yasuhiro Oue , Yuko Yamakoshi , Satoshi Sugiura , Robert Dale Mitchell , James Donald Simpson , John Clifford Harris , Joelle Le
发明人： Kenichiro Kataoka , Naotaka Suzuki , Tomomi Kosugi , Minoru Imai , Hiroaki Makino , Mika Takakuwa , Gen Unoki , Aiko Fujino , Yasuhiro Oue , Yuko Yamakoshi , Satoshi Sugiura , Robert Dale Mitchell , James Donald Simpson , John Clifford Harris , Joelle Le
IPC分类号： C07D487/04 , A61K31/519
CPC分类号： C07D487/04
摘要： The Pyrazolo[1,5-a]pyrimidine derivatives represented by formula I and their pharmaceutically acceptable salts exhibit excellent kinase inhibiting activity. Drugs comprising the compounds as effective ingredients are therefore expected to be useful as therapeutic or prophylactic agents for a protein kinase mediated disorder in which kinase is implicated, such as inflammatory disease, autoimmune disease, destructive bone disorder, cancer and/or tumour growth.
摘要翻译：由式I表示的吡唑并[1,5-a]嘧啶衍生物及其药学上可接受的盐表现出优异的激酶抑制活性。因此，包含化合物作为有效成分的药物预期可用作其中涉及激酶的蛋白激酶介导的病症的治疗或预防剂，例如炎性疾病，自身免疫疾病，破坏性骨病，癌症和/或肿瘤生长。

3. 发明授权

US08202962B2 Integrated steam heating in polyester production process 有权
标题翻译：在聚酯生产过程中集成蒸汽加热
公开(公告)号：US08202962B2
公开(公告)日：2012-06-19
申请号：US12558020
申请日：2009-09-11
申请人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
发明人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
IPC分类号： C08G63/02 , C08G63/00
CPC分类号： C08G63/78 , Y02P20/125
摘要： Processes for making polyesters in a polyester production facility are disclosed, that include the steps of: forming a reaction medium comprising at least one monomer that includes terephthalic acid (TPA) and/or an ester derivative of TPA; subjecting at least a portion of the reaction medium to one or more chemical reactions in the polyester production facility to thereby produce the polyester; heating at least a portion of the reaction medium via indirect heat exchange with high-pressure steam, wherein the heating causes at least a portion of the high-pressure steam to condense and thereby provide pressurized condensed water; flashing at least a portion of the pressurized condensed water to thereby produce lower-pressure steam; and heating one or more process fluid streams of the polyester production facility via indirect heat exchange with at least a portion of the lower-pressure steam, wherein the process fluid streams include any stream that is formed predominately of the reaction medium and/or the at least one monomer.
摘要翻译：公开了在聚酯生产设备中制备聚酯的方法，其包括以下步骤：形成包含至少一种包含对苯二甲酸（TPA）和/或TPA的酯衍生物的单体的反应介质; 使至少一部分反应介质在聚酯制造设备中进行一次或多次化学反应，从而制造聚酯; 通过与高压蒸汽的间接热交换来加热至少一部分反应介质，其中加热使至少一部分高压蒸汽冷凝，从而提供加压的冷凝水; 闪烁至少一部分加压冷凝水，从而产生低压蒸汽; 以及通过与所述低压蒸汽的至少一部分的间接热交换来加热所述聚酯生产设备的一个或多个过程流体流，其中所述过程流体流包括主要由所述反应介质和/或所述反应介质形成的任何流至少一种单体。

4. 发明授权

US08198397B2 Integrated steam heating in polyester production process 有权
标题翻译：在聚酯生产过程中集成蒸汽加热
公开(公告)号：US08198397B2
公开(公告)日：2012-06-12
申请号：US12558003
申请日：2009-09-11
申请人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
发明人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
IPC分类号： C08G64/00 , C08G63/02
CPC分类号： C08G63/78 , Y02P20/125
摘要： Integrated processes for making polyesters are disclosed, that include the steps of: (a) producing an aromatic polycarboxylic acid in a monomer production facility; (b) producing a polyester in a polyester production facility, wherein the producing of the polyester comprises the substeps of: (i) forming a polyester reaction medium comprising at least a portion of the aromatic polycarboxylic acid from the monomer production facility, (ii) subjecting at least a portion of the polyester reaction medium to one or more chemical reactions to thereby produce the polyester, (iii) heating the polyester reaction medium at one or more locations in the polyester production facility via indirect heat exchange with high-pressure steam, wherein the heating causes at least a portion of the high-pressure steam to condense and thereby provide pressurized condensed water, and (iv) flashing at least a portion of the pressurized condensed water to thereby produce lower-pressure steam; and (c) using at least a portion of the lower-pressure steam to provide thermal energy to the monomer production facility.
摘要翻译：公开了制造聚酯的综合方法，包括以下步骤：（a）在单体生产设备中制备芳族多元羧酸; （b）在聚酯制造设备中制造聚酯，其中聚酯的制造包括以下子步骤：（i）从单体生产设备形成包含至少一部分芳族多元羧酸的聚酯反应介质，（ii）使聚酯反应介质的至少一部分进行一个或多个化学反应从而生产聚酯，（iii）通过与高压蒸汽的间接热交换在聚酯生产设备中的一个或多个位置处加热聚酯反应介质，其中所述加热使得所述高压蒸汽的至少一部分冷凝，从而提供加压的冷凝水，和（iv）使加压冷凝水的至少一部分闪蒸，从而产生低压蒸汽; 和（c）使用至少一部分低压蒸汽来向单体生产设备提供热能。

5. 发明授权

US08017723B2 Steam heated polyester production process 有权
标题翻译：蒸汽加热聚酯生产工艺
公开(公告)号：US08017723B2
公开(公告)日：2011-09-13
申请号：US12557974
申请日：2009-09-11
申请人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
发明人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
IPC分类号： C08G63/02 , C08G64/00
CPC分类号： C08G63/785 , C08G63/183
摘要： Processes for making polyesters in a polyester production facility are disclosed, that include the steps of forming a reaction medium comprising at least one monomer that includes terephthalic acid (TPA) and/or an ester derivative of TPA; subjecting at least a portion of the reaction medium to one or more chemical reactions in the polymer production facility to thereby produce the polyester; and heating the reaction medium at one or more locations in the polyester production facility, wherein at least 50 percent of the total energy input employed for the heating of the reaction medium is provided by indirect heat exchange between the reaction medium and steam.
摘要翻译：公开了在聚酯制造设备中制造聚酯的方法，包括形成包含至少一种包含对苯二甲酸（TPA）和/或TPA的酯衍生物的单体的反应介质的步骤; 使至少一部分反应介质在聚合物生产设备中进行一个或多个化学反应，从而生产聚酯; 并且在聚酯生产设备中的一个或多个位置处加热反应介质，其中用于加热反应介质的总能量输入的至少50％由反应介质和蒸汽之间的间接热交换提供。

6. 发明授权

US08013110B2 Steam heated polyester production process 有权
标题翻译：蒸汽加热聚酯生产工艺
公开(公告)号：US08013110B2
公开(公告)日：2011-09-06
申请号：US12557953
申请日：2009-09-11
申请人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
发明人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
IPC分类号： C08G64/00 , C08G63/02
CPC分类号： C08G63/785 , C08G63/183
摘要： Processes for making polyesters in a polyester production facility are disclosed, that include the steps of: forming a reaction medium comprising at least one monomer that includes terephthalic acid (TPA) and/or an ester derivative of TPA; subjecting at least a portion of the reaction medium to one or more chemical reactions in the polyester production facility to thereby produce the polyester; generating high-pressure steam having a pressure of at least 5 megapascals; heating one or more process fluid streams of the polyester production facility by indirect heat exchange with the high-pressure steam, wherein the process fluid streams include any stream that is formed predominately of the reaction medium and/or the at least one monomer; heating a heat transfer medium (HTM) via indirect heat exchange with the high-pressure steam to thereby form heated HTM; and heating at least a portion of the process fluid streams by indirect heat exchange with the heated HTM.
摘要翻译：公开了在聚酯生产设备中制备聚酯的方法，其包括以下步骤：形成包含至少一种包含对苯二甲酸（TPA）和/或TPA的酯衍生物的单体的反应介质; 使至少一部分反应介质在聚酯制造设备中进行一次或多次化学反应，从而制造聚酯; 产生具有至少5兆帕斯卡的压力的高压蒸汽; 通过与高压蒸汽间接热交换来加热聚酯生产设备的一个或多个工艺流体流，其中工艺流体流包括主要由反应介质和/或至少一种单体形成的任何流; 通过与高压蒸汽的间接热交换来加热传热介质（HTM），从而形成加热的HTM; 以及通过与加热的HTM的间接热交换来加热至少一部分工艺流体流。

7. 发明申请

US20100113714A1 INTEGRATED STEAM HEATING IN POLYESTER PRODUCTION PROCESS 有权
标题翻译：聚酯生产过程中的一体化蒸汽加热
公开(公告)号：US20100113714A1
公开(公告)日：2010-05-06
申请号：US12558020
申请日：2009-09-11
申请人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
发明人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
IPC分类号： C08G63/127 , C08F2/01
CPC分类号： C08G63/78 , Y02P20/125
摘要： Processes for making polyesters in a polyester production facility are disclosed, that include the steps of: forming a reaction medium comprising at least one monomer that includes terephthalic acid (TPA) and/or an ester derivative of TPA; subjecting at least a portion of the reaction medium to one or more chemical reactions in the polyester production facility to thereby produce the polyester; heating at least a portion of the reaction medium via indirect heat exchange with high-pressure steam, wherein the heating causes at least a portion of the high-pressure steam to condense and thereby provide pressurized condensed water; flashing at least a portion of the pressurized condensed water to thereby produce lower-pressure steam; and heating one or more process fluid streams of the polyester production facility via indirect heat exchange with at least a portion of the lower-pressure steam, wherein the process fluid streams include any stream that is formed predominately of the reaction medium and/or the at least one monomer.
摘要翻译：公开了在聚酯生产设备中制备聚酯的方法，其包括以下步骤：形成包含至少一种包含对苯二甲酸（TPA）和/或TPA的酯衍生物的单体的反应介质; 使至少一部分反应介质在聚酯制造设备中进行一次或多次化学反应，从而制造聚酯; 通过与高压蒸汽的间接热交换来加热至少一部分反应介质，其中加热使至少一部分高压蒸汽冷凝，从而提供加压的冷凝水; 闪烁至少一部分加压冷凝水，从而产生低压蒸汽; 以及通过与所述低压蒸汽的至少一部分的间接热交换来加热所述聚酯生产设备的一个或多个过程流体流，其中所述过程流体流包括主要由所述反应介质和/或所述反应介质形成的任何流至少一种单体。

8. 发明申请

US20100113713A1 STEAM HEATED POLYESTER PRODUCTION PROCESS 有权
标题翻译：蒸汽加热聚酯生产工艺
公开(公告)号：US20100113713A1
公开(公告)日：2010-05-06
申请号：US12557974
申请日：2009-09-11
申请人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
发明人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
IPC分类号： C08F2/01 , C08G63/02
CPC分类号： C08G63/785 , C08G63/183
摘要： Processes for making polyesters in a polyester production facility are disclosed, that include the steps of forming a reaction medium comprising at least one monomer that includes terephthalic acid (TPA) and/or an ester derivative of TPA; subjecting at least a portion of the reaction medium to one or more chemical reactions in the polymer production facility to thereby produce the polyester; and heating the reaction medium at one or more locations in the polyester production facility, wherein at least 50 percent of the total energy input employed for the heating of the reaction medium is provided by indirect heat exchange between the reaction medium and steam.
摘要翻译：公开了在聚酯制造设备中制造聚酯的方法，包括形成包含至少一种包含对苯二甲酸（TPA）和/或TPA的酯衍生物的单体的反应介质的步骤; 使至少一部分反应介质在聚合物生产设备中进行一个或多个化学反应，从而生产聚酯; 并且在聚酯生产设备中的一个或多个位置处加热反应介质，其中用于加热反应介质的总能量输入的至少50％由反应介质和蒸汽之间的间接热交换提供。

9. 发明申请

US20100113712A1 STEAM HEATED POLYESTER PRODUCTION PROCESS 有权
标题翻译：蒸汽加热聚酯生产工艺
公开(公告)号：US20100113712A1
公开(公告)日：2010-05-06
申请号：US12557953
申请日：2009-09-11
申请人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
发明人： Alan George Wonders , James Donald Simpson , Bruce Roger DeBruin
IPC分类号： C08F2/01 , C08G63/02
CPC分类号： C08G63/785 , C08G63/183
摘要： Processes for making polyesters in a polyester production facility are disclosed, that include the steps of: forming a reaction medium comprising at least one monomer that includes terephthalic acid (TPA) and/or an ester derivative of TPA; subjecting at least a portion of the reaction medium to one or more chemical reactions in the polyester production facility to thereby produce the polyester; generating high-pressure steam having a pressure of at least 5 megapascals; heating one or more process fluid streams of the polyester production facility by indirect heat exchange with the high-pressure steam, wherein the process fluid streams include any stream that is formed predominately of the reaction medium and/or the at least one monomer; heating a heat transfer medium (HTM) via indirect heat exchange with the high-pressure steam to thereby form heated HTM; and heating at least a portion of the process fluid streams by indirect heat exchange with the heated HTM.
摘要翻译：公开了在聚酯生产设备中制备聚酯的方法，其包括以下步骤：形成包含至少一种包含对苯二甲酸（TPA）和/或TPA的酯衍生物的单体的反应介质; 使至少一部分反应介质在聚酯制造设备中进行一次或多次化学反应，从而制造聚酯; 产生具有至少5兆帕斯卡的压力的高压蒸汽; 通过与高压蒸汽间接热交换来加热聚酯生产设备的一个或多个工艺流体流，其中工艺流体流包括主要由反应介质和/或至少一种单体形成的任何流; 通过与高压蒸汽的间接热交换来加热传热介质（HTM），从而形成加热的HTM; 以及通过与加热的HTM的间接热交换来加热至少一部分工艺流体流。

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