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1. 发明申请

US20080013687A1 Automatically determining size or shape of a radiation beam 审中-公开
标题翻译：自动确定辐射束的大小或形状
公开(公告)号：US20080013687A1
公开(公告)日：2008-01-17
申请号：US11731145
申请日：2007-03-30
申请人： Calvin Maurer , Jay West , John Allison
发明人： Calvin Maurer , Jay West , John Allison
IPC分类号： G21K1/00
CPC分类号： A61N5/103 , A61N5/1036 , A61N5/1042 , G21K1/046
摘要： Systems and methods for automatically determining a beam parameter at each of a plurality of treatment nodes are disclosed. The beam parameter may include a beam shape, beam size and/or beam orientation. Systems and methods for automatically selecting multiple collimators in a radiation treatment system are also disclosed.
摘要翻译：公开了用于在多个处理节点中的每一个处自动确定波束参数的系统和方法。光束参数可以包括光束形状，光束尺寸和/或光束取向。还公开了用于在辐射处理系统中自动选择多个准直器的系统和方法。

2. 发明申请

US20070053490A1 Automatic generation of an envelope of constraint points for inverse planning 有权
标题翻译：自动生成用于反向规划的约束点的包络
公开(公告)号：US20070053490A1
公开(公告)日：2007-03-08
申请号：US11220838
申请日：2005-09-06
申请人： Hongwu Wang , Jay West , John Dooley
发明人： Hongwu Wang , Jay West , John Dooley
IPC分类号： A61N5/10
CPC分类号： A61N5/1031
摘要： A method of automatically generating an envelope of constraint points for a target region to optimize an inverse treatment plan by modifying the dose isocontour.
摘要翻译：一种自动产生目标区域约束点包络的方法，以通过修改剂量等值线来优化逆治疗计划。

3. 发明申请

US20070038058A1 Patient tracking using a virtual image 有权
标题翻译：患者跟踪使用虚拟图像
公开(公告)号：US20070038058A1
公开(公告)日：2007-02-15
申请号：US11202842
申请日：2005-08-11
申请人： Jay West , Dongshan Fu
发明人： Jay West , Dongshan Fu
IPC分类号： A61B5/05
CPC分类号： A61N5/1049 , A61B6/584 , A61B90/36 , A61B2090/364 , A61N5/1065 , A61N2005/1058 , A61N2005/1061
摘要： An apparatus and method of tracking a patient using a virtual image.
摘要翻译：使用虚拟图像跟踪患者的装置和方法。

4. 发明申请

US20060274924A1 Inverse planning using optimization constraints derived from image intensity 有权
标题翻译：使用从图像强度导出的优化约束的反向规划
公开(公告)号：US20060274924A1
公开(公告)日：2006-12-07
申请号：US11144235
申请日：2005-06-02
申请人： Jay West , Michael Saracen , John Dooley
发明人： Jay West , Michael Saracen , John Dooley
IPC分类号： G06K9/00
CPC分类号： A61N5/103 , A61N5/1039
摘要： A method of automatically identifying a region of differing intensity in a functional image is described.
摘要翻译：描述了在功能图像中自动识别不同强度区域的方法。

5. 发明申请

US20050218341A1 Treatment target positioning system 有权
标题翻译：治疗目标定位系统
公开(公告)号：US20050218341A1
公开(公告)日：2005-10-06
申请号：US10881595
申请日：2004-06-30
申请人： Michael Saracen , Jay West
发明人： Michael Saracen , Jay West
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61N5/1069 , A61N2005/105 , A61N2005/1059
摘要： A wireless treatment target positioning system for therapeutic radiation treatment includes a patient positioning system and a treatment target locating system. The treatment target locating system includes a room beam coordinate system and a localizing system. The room beam coordinate system includes devices for generating laser beams intersecting at a single point that is spatially coincident with an iso-center of the treatment system. The localizing system includes a movable reference object and a localizer for detecting and determining the position of the movable reference object. A method of positioning a treatment target to the iso-center of the treatment system includes a simulation process and real treatment positioning process. The simulation process includes positioning the treatment target to an iso-center of a simulation system and marking intersection points where laser beams intersect with an exterior of the patient's body. The real treatment positioning process includes determining the position of the intersection points marked on the exterior of the patient body, determining a treatment position for positioning the patient such that the treatment target is aligned with the iso-center of the real treatment system, and positioning the patient to the treatment position.
摘要翻译：用于治疗性放射治疗的无线治疗目标定位系统包括患者定位系统和治疗目标定位系统。治疗目标定位系统包括房间梁坐标系和定位系统。房间光束坐标系包括用于产生与空间上与处理系统的等中心一致的单个点相交的激光束的装置。定位系统包括可移动参考物体和定位器，用于检测和确定可移动参考物体的位置。将治疗目标定位到治疗系统的等中心的方法包括模拟过程和实际治疗定位过程。模拟过程包括将治疗目标定位到模拟系统的等中心，并标记激光束与患者身体外部相交的交点。真正的治疗定位过程包括确定标记在患者身体外部的交叉点的位置，确定用于定位患者的治疗位置，使得治疗目标与实际治疗系统的等中心对准，并且定位病人到治疗位置。

6. 发明申请

US20070078306A1 Wizard and template for treatment planning 有权
标题翻译：向导和模板进行治疗计划
公开(公告)号：US20070078306A1
公开(公告)日：2007-04-05
申请号：US11242219
申请日：2005-09-30
申请人： John Allison , John Dooley , Jay West , Gopinath Kuduvalli , Hongwu Wang , Jin-Wu Wang , Warren Kilby , Derek Olender , Michael Saracen
发明人： John Allison , John Dooley , Jay West , Gopinath Kuduvalli , Hongwu Wang , Jin-Wu Wang , Warren Kilby , Derek Olender , Michael Saracen
IPC分类号： A61B5/00
CPC分类号： A61N5/103
摘要： A method and apparatus for treatment planning are described.
摘要翻译：描述了治疗计划的方法和装置。

7. 发明申请

US20060274061A1 Four-dimensional volume of interest 有权
标题翻译：四维感兴趣的体积
公开(公告)号：US20060274061A1
公开(公告)日：2006-12-07
申请号：US11144247
申请日：2005-06-02
申请人： Hongwu Wang , John Dooley , Jay West
发明人： Hongwu Wang , John Dooley , Jay West
IPC分类号： G06T17/00
CPC分类号： G06T19/00 , A61N5/103 , A61N5/1037 , G06T7/0012 , G06T7/20 , G06T15/08 , G06T2207/10076 , G06T2207/30096
摘要： A method and apparatus for a four-dimensional volume of interest is described.
摘要翻译：描述了一种四维感兴趣体积的方法和装置。

8. 发明申请

US20060170679A1 Representing a volume of interest as boolean combinations of multiple simple contour sets 审中-公开
标题翻译：将多个简单轮廓集合的布尔组合表示为感兴趣的体积
公开(公告)号：US20060170679A1
公开(公告)日：2006-08-03
申请号：US11049501
申请日：2005-02-01
申请人： Hongwu Wang , Jay West , John Dooley
发明人： Hongwu Wang , Jay West , John Dooley
IPC分类号： G06T17/00
CPC分类号： G06T17/00
摘要： An apparatus and method of representing a volume of interest as Boolean combinations of multiple simple contour sets.
摘要翻译：将多个简单轮廓集合的布尔组合表示感兴趣体积的装置和方法。

9. 发明申请

US20060063160A1 Microfluidic microarray systems and methods thereof 有权
公开(公告)号：US20060063160A1
公开(公告)日：2006-03-23
申请号：US10946920
申请日：2004-09-22
申请人： Jay West , Kyle Hukari , Gary Hux
发明人： Jay West , Kyle Hukari , Gary Hux
IPC分类号： C12Q1/68 , C12M1/34
CPC分类号： B01L3/0293 , B01J2219/00387 , B01J2219/00527 , B01J2219/00576 , B01J2219/00659 , B01J2219/00722 , B01L3/502715 , B01L3/565 , B01L7/52 , B01L9/527 , B01L2200/027 , B01L2200/10 , B01L2300/0636 , B01L2300/0654 , B01L2300/0877 , B01L2300/18 , B01L2300/1894 , B01L2400/0487 , C12Q1/6837 , G01N21/0303 , C12Q2565/629
摘要： Disclosed are systems that include a manifold in fluid communication with a microfluidic chip having a microarray, an illuminator, and a detector in optical communication with the microarray. Methods for using these systems for biological detection are also disclosed.

10. 发明授权

US09108048B2 Systems and methods for real-time tumor tracking during radiation treatment using ultrasound imaging 有权
标题翻译：使用超声成像进行放射治疗期间实时肿瘤跟踪的系统和方法
公开(公告)号：US09108048B2
公开(公告)日：2015-08-18
申请号：US13204559
申请日：2011-08-05
申请人： Calvin R. Maurer, Jr. , Jay West , Petr Jordan
发明人： Calvin R. Maurer, Jr. , Jay West , Petr Jordan
IPC分类号： A61B5/055 , A61B6/02 , A61B8/14 , A61N5/10 , A61B6/00 , A61B8/08 , A61B6/04 , A61B8/00
CPC分类号： A61N5/1049 , A61B5/055 , A61B6/022 , A61B6/032 , A61B6/0457 , A61B6/4417 , A61B6/4458 , A61B6/5247 , A61B8/08 , A61B8/085 , A61B8/4218 , A61B8/4245 , A61B8/4263 , A61B8/4416 , A61B8/4444 , A61B8/483 , A61B8/5238 , A61B8/5261 , A61B90/39 , A61B2090/3995 , A61N5/1039 , A61N5/1045 , A61N5/1067 , A61N5/107 , A61N5/1077 , A61N5/1081 , A61N5/1083 , A61N2005/1054 , A61N2005/1055 , A61N2005/1058 , A61N2005/1061 , A61N2005/1062
摘要： Systems and methods for tracking a target volume, e.g., tumor, in real-time during radiation treatment are provided. Under one aspect, a system includes an ultrasound probe, an x-ray imager, a processor, and a computer-readable medium that stores a 3D image of the tumor in a first reference frame and instructions for causing the processor to: instruct the x-ray imager and ultrasound probe to substantially simultaneously obtain inherently registered x-ray and set-up ultrasound images of the tumor in a second reference frame; establish a transformation between the first and second reference frames by registering the 3D image and the x-ray image; instruct the ultrasound probe to obtain an intrafraction ultrasound image of the tumor; registering the intrafraction ultrasound image with the set-up ultrasound image; and track target volume motion based on the registered intrafraction ultrasound image.
摘要翻译：提供了用于在放射治疗期间实时跟踪目标体积（例如肿瘤）的系统和方法。在一个方面，一种系统包括超声波探头，X射线成像仪，处理器和将肿瘤的3D图像存储在第一参考系中的计算机可读介质，以及用于使处理器执行以下操作的指令：指示x 射线成像仪和超声探头基本上同时获得在第二参考系中肿瘤的固有的x射线和设置的超声图像; 通过注册3D图像和X射线图像来建立第一和第二参考帧之间的变换; 指示超声探头获得肿瘤的分数内超声图像; 用建立的超声图像记录影像内图像; 并且基于注册的分数内超声图像跟踪目标体积运动。

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