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1. 发明申请

US20120215305A1 ADJUSTABLE ANNULOPLASTY RING AND ACTIVATION SYSTEM 审中-公开
标题翻译：可调节的静脉环和活动系统
公开(公告)号：US20120215305A1
公开(公告)日：2012-08-23
申请号：US13397945
申请日：2012-02-16
申请人： Le Le , Jason Tran , Jesus Flores , Kelly Mac
发明人： Le Le , Jason Tran , Jesus Flores , Kelly Mac
IPC分类号： A61F2/24
CPC分类号： A61F2/2448 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00867 , A61B2018/00821 , A61B2218/002 , A61F2/2445 , A61F2210/0038 , A61F2250/0001 , A61F2250/0004 , C08L2201/12
摘要： An adjustable implantable medical device and adjustment device are described. In some embodiments, the adjustment device includes a lead with a distal end modified to permit better engagement and securement to the described implantable devices. In some embodiments, the contact of the lead is bent. Some embodiments include a coil that engages and secures the lead to the implantable device. Some embodiments include a suture line to aid in securing the lead to the implantable device.
摘要翻译：描述了一种可调式可植入医疗装置和调节装置。在一些实施例中，调节装置包括具有被修改以允许更好地接合和固定到所描述的可植入装置的远端的引线。在一些实施例中，引线的接触是弯曲的。一些实施例包括将引线接合并固定到可植入装置的线圈。一些实施例包括有助于将引线固定到可植入装置的缝合线。

2. 发明申请

US20070239154A1 Activation device for dynamic ring manipulation 失效
标题翻译：用于动态环操作的激活设备
公开(公告)号：US20070239154A1
公开(公告)日：2007-10-11
申请号：US11728010
申请日：2007-03-22
申请人： Samuel Shaolian , Shahram Moaddeb , Maurice Buchbinder , David Zarbatany , Jason Tran
发明人： Samuel Shaolian , Shahram Moaddeb , Maurice Buchbinder , David Zarbatany , Jason Tran
IPC分类号： A61F2/24 , A61B18/18
CPC分类号： A61F2/2445 , A61F2/2466 , A61F2250/0001
摘要： An activation device for applying energy to an implanted annuloplasty ring is described. In some embodiments, the activation device includes an outer elongate member having an outer elongate member distal end and an outer elongate member proximal end, and a lumen therebetween. In some embodiments, the activation device further includes an inner elongate member having a inner elongate member distal end and a inner elongate member proximal end, and a lumen therebetween, wherein the inner elongate member is slidably insertable through the lumen of the outer elongate member. In some embodiments, the activation device further includes at least one adjustable spline having spline proximal and spline distal ends, the spline distal end connected to the inner tubular member distal end and the spline proximal end connected to the outer tubular member distal end, wherein the adjustable spline is configured to flex as the inner tubular member distal end is drawn proximally toward the outer tubular member distal end while the inner elongate member resides in the lumen of the outer elongate member. In some embodiments, the activation device further includes at least one energy-transfer element coupled to the adjustable spline.
摘要翻译：描述了一种用于向植入的瓣膜成形术环施加能量的激活装置。在一些实施例中，激活装置包括具有外部细长构件远端和外部细长构件近端的外部细长构件和其间的内腔。在一些实施例中，激活装置还包括具有内部细长构件远端和内部细长构件近端的内部细长构件和其间的内腔，其中内部细长构件可滑动地插入穿过外部细长构件的内腔。在一些实施例中，激活装置还包括具有花键近端和花键远端的至少一个可调节花键，花键远端连接到内部管状构件远端，花键近端连接到外部管状构件远端，其中，当内部细长构件驻留在外部细长构件的内腔中时，可调节花键构造成随着内部管状构件远端朝向外部管状构件远端被拉近而弯曲。在一些实施例中，激活装置还包括耦合到可调节花键的至少一个能量传递元件。

3. 发明申请

US20090216322A1 ADJUSTABLE ANNULOPLASTY RING AND ACTIVATION SYSTEM 审中-公开
标题翻译：可调节的静脉环和活动系统
公开(公告)号：US20090216322A1
公开(公告)日：2009-08-27
申请号：US12188964
申请日：2008-08-08
申请人： Le Le , Jason Tran , Jesus Flores , Kelly Mac
发明人： Le Le , Jason Tran , Jesus Flores , Kelly Mac
IPC分类号： A61F2/24
CPC分类号： A61F2/2448 , A61B18/1492 , A61B18/18 , A61B18/20 , A61B2017/00867 , A61B2018/00821 , A61B2218/002 , A61F2/2445 , A61F2210/0038 , A61F2250/0001 , A61F2250/0004 , C08L2201/12
摘要： An adjustable implantable medical device and adjustment device are described. In some embodiments, the adjustment device includes a lead with a distal end modified to permit better engagement and securement to the described implantable devices. In some embodiments, the contact of the lead is bent. Some embodiments include a coil that engages and secures the lead to the implantable device. Some embodiments include a suture line to aid in securing the lead to the implantable device.
摘要翻译：描述了一种可调式可植入医疗装置和调节装置。在一些实施例中，调节装置包括具有被修改以允许更好地接合和固定到所描述的可植入装置的远端的引线。在一些实施例中，引线的接触是弯曲的。一些实施例包括将引线接合并固定到可植入装置的线圈。一些实施例包括有助于将引线固定到可植入装置的缝合线。

4. 发明申请

US20070276478A1 Intraoperative and post-operative adjustment of an annuloplasty ring 审中-公开
标题翻译：手术和手术后瓣膜成形术环的调整
公开(公告)号：US20070276478A1
公开(公告)日：2007-11-29
申请号：US11801927
申请日：2007-05-11
申请人： Alexander Marmureanu , Le Le , Jesus Flores , Jason Tran , Samuel Shaolian
发明人： Alexander Marmureanu , Le Le , Jesus Flores , Jason Tran , Samuel Shaolian
IPC分类号： A61F2/24
CPC分类号： A61F2/2448 , A61F2/2445 , A61F2210/0038 , A61F2250/0001 , A61F2250/0004
摘要： An intraoperative adjustment device is described. In some embodiments, the device includes an elongate body including a proximal end and a distal end, the distal end configured to penetrate an outer surface of an adjustable cardiac implant implanted in a patient's heart, and the proximal end and the distal end connected by at least one energy-transfer member. In some embodiments, the distal end includes at least one electrode coupled to the energy-transfer member and configured to deliver an activation energy to the adjustable cardiac implant. In some embodiments, the proximal end is configured to attach to an energy source that provides the activation energy. In some embodiments, the proximal end is configured to be located outside the patient's body while the distal end is coupled to the adjustable cardiac implant that is implanted in the patient's heart.
摘要翻译：描述了术中调整装置。在一些实施例中，该装置包括细长主体，其包括近端和远端，远端构造为穿透植入患者心脏的可调心脏植入物的外表面，并且近端和远端通过至少一个能量传递构件。在一些实施例中，远端包括耦合到能量传递构件并且被配置为将活化能传递到可调心脏植入物的至少一个电极。在一些实施例中，近端被配置为附接到提供激活能量的能量源。在一些实施例中，近端构造成位于患者身体外部，而远端联接到植入患者心脏的可调心脏植入物。

5. 发明申请

US20120209379A1 ADJUSTABLE ANNULOPLASTY RING AND ACTIVATION SYSTEM 审中-公开
标题翻译：可调节的静脉环和活动系统
公开(公告)号：US20120209379A1
公开(公告)日：2012-08-16
申请号：US13316086
申请日：2011-12-09
申请人： Samuel M. Shaolian , Le Le , Jesus Flores , Jason Tran
发明人： Samuel M. Shaolian , Le Le , Jesus Flores , Jason Tran
IPC分类号： A61F2/24
CPC分类号： A61F2/2448 , A61F2/2445 , A61F2210/0038 , A61F2250/0001 , A61F2250/0004
摘要： An adjustable annuloplasty device is described. In some embodiments, the device includes a body member having a surface that conforms at least partially to a cardiac valve annulus. The body member comprises a shape-memory member that transforms from a first configuration to a second configuration in response to an applied energy. In some embodiments, the device further includes a first electrode assembly, coupled to the shape-memory member, that transfers energy to the shape-memory member, and a second electrode assembly, coupled to the shape-memory member, that transfers at least a portion of the energy away from the shape-memory member.
摘要翻译：描述了可调环形成形术装置。在一些实施例中，该装置包括具有至少部分地与心脏瓣膜环相一致的表面的主体构件。身体构件包括形状记忆构件，其响应于所施加的能量从第一构型变换到第二构造。在一些实施例中，该装置还包括耦合到形状记忆构件的第一电极组件，其将能量传递到形状记忆构件，以及耦合到形状记忆构件的第二电极组件，其传送至少一个部分能量远离形状记忆部件。

6. 发明申请

US20090088838A1 ADJUSTABLE ANNULOPLASTY RING AND ACTIVATION SYSTEM 审中-公开
标题翻译：可调节的静脉环和活动系统
公开(公告)号：US20090088838A1
公开(公告)日：2009-04-02
申请号：US12057594
申请日：2008-03-28
申请人： Samuel M. Shaolian , Le Le , Jesus Flores , Jason Tran
发明人： Samuel M. Shaolian , Le Le , Jesus Flores , Jason Tran
IPC分类号： A61F2/24
CPC分类号： A61F2/2448 , A61F2/2445 , A61F2210/0038 , A61F2250/0001 , A61F2250/0004
摘要： An adjustable annuloplasty device is described. In some embodiments, the device includes a body member having a surface that conforms at least partially to a cardiac valve annulus. The body member comprises a shape-memory member that transforms from a first configuration to a second configuration in response to an applied energy. In some embodiments, the device further includes a first electrode assembly, coupled to the shape-memory member, that transfers energy to the shape-memory member, and a second electrode assembly, coupled to the shape-memory member, that transfers at least a portion of the energy away from the shape-memory member.
摘要翻译：描述了可调环形成形术装置。在一些实施例中，该装置包括具有至少部分地与心脏瓣膜环相一致的表面的主体构件。身体构件包括形状记忆构件，其响应于所施加的能量从第一构型变换到第二构造。在一些实施例中，该装置还包括耦合到形状记忆构件的第一电极组件，其将能量传递到形状记忆构件，以及耦合到形状记忆构件的第二电极组件，其传送至少一个部分能量远离形状记忆部件。

7. 发明申请

US20120136433A1 INTRAOPERATIVE AND POST-OPERATIVE ADJUSTMENT OF AN ANNULOPLASTY RING 审中-公开
标题翻译：手术和手术后调整ANNOPOPLASTY环
公开(公告)号：US20120136433A1
公开(公告)日：2012-05-31
申请号：US13172531
申请日：2011-06-29
申请人： Alexander MARMUREANU , Le LE , Jesus FLORES , Jason TRAN , Samuel SHAOLIAN
发明人： Alexander MARMUREANU , Le LE , Jesus FLORES , Jason TRAN , Samuel SHAOLIAN
IPC分类号： A61F2/24
CPC分类号： A61F2/2448 , A61F2/2445 , A61F2210/0038 , A61F2250/0001 , A61F2250/0004
摘要： An intraoperative adjustment device is described. In some embodiments, the device includes an elongate body including a proximal end and a distal end, the distal end configured to penetrate an outer surface of an adjustable cardiac implant implanted in a patient's heart, and the proximal end and the distal end connected by at least one energy-transfer member. In some embodiments, the distal end includes at least one electrode coupled to the energy-transfer member and configured to deliver an activation energy to the adjustable cardiac implant. In some embodiments, the proximal end is configured to attach to an energy source that provides the activation energy. In some embodiments, the proximal end is configured to be located outside the patient's body while the distal end is coupled to the adjustable cardiac implant that is implanted in the patient's heart.
摘要翻译：描述了术中调整装置。在一些实施例中，该装置包括细长主体，其包括近端和远端，远端构造为穿透植入患者心脏的可调心脏植入物的外表面，并且近端和远端通过至少一个能量传递构件。在一些实施例中，远端包括耦合到能量传递构件并且被配置为将活化能传递到可调心脏植入物的至少一个电极。在一些实施例中，近端被配置为附接到提供激活能量的能量源。在一些实施例中，近端构造成位于患者身体外部，而远端联接到植入患者心脏的可调心脏植入物。

8. 发明授权

US07536228B2 Activation device for dynamic ring manipulation 失效
标题翻译：用于动态环操作的激活设备
公开(公告)号：US07536228B2
公开(公告)日：2009-05-19
申请号：US11728010
申请日：2007-03-22
申请人： Samuel Shaolian , Shahram Moaddeb , Maurice Buchbinder , David Zarbatany , Jason Tran
发明人： Samuel Shaolian , Shahram Moaddeb , Maurice Buchbinder , David Zarbatany , Jason Tran
IPC分类号： A61N1/18
CPC分类号： A61F2/2445 , A61F2/2466 , A61F2250/0001
摘要： An activation device for applying energy to an implanted annuloplasty ring is described. In some embodiments, the activation device includes an outer elongate member having an outer elongate member distal end and an outer elongate member proximal end, and a lumen therebetween. In some embodiments, the activation device further includes an inner elongate member having a inner elongate member distal end and a inner elongate member proximal end, and a lumen therebetween, wherein the inner elongate member is slidably insertable through the lumen of the outer elongate member. In some embodiments, the activation device further includes at least one adjustable spline having spline proximal and spline distal ends, the spline distal end connected to the inner tubular member distal end and the spline proximal end connected to the outer tubular member distal end, wherein the adjustable spline is configured to flex as the inner tubular member distal end is drawn proximally toward the outer tubular member distal end while the inner elongate member resides in the lumen of the outer elongate member. In some embodiments, the activation device further includes at least one energy-transfer element coupled to the adjustable spline.
摘要翻译：描述了一种用于向植入的瓣膜成形术环施加能量的激活装置。在一些实施例中，激活装置包括具有外部细长构件远端和外部细长构件近端的外部细长构件和其间的内腔。在一些实施例中，激活装置还包括具有内部细长构件远端和内部细长构件近端的内部细长构件和其间的内腔，其中内部细长构件可滑动地插入穿过外部细长构件的内腔。在一些实施例中，激活装置还包括具有花键近端和花键远端的至少一个可调节花键，花键远端连接到内部管状构件远端，花键近端连接到外部管状构件远端，其中，当内部细长构件驻留在外部细长构件的内腔中时，可调节花键构造成随着内部管状构件远端朝向外部管状构件远端被拉近而弯曲。在一些实施例中，激活装置还包括耦合到可调节花键的至少一个能量传递元件。

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