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1. 发明申请

WO2012080087A1 INJECTION SUPPORTING DEVICE FOR A SYRINGE AND INJECTION DEVICE 审中-公开
标题翻译：注射装置的注射支持装置
公开(公告)号：WO2012080087A1
公开(公告)日：2012-06-21
申请号：PCT/EP2011/072237
申请日：2011-12-08
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , HEMMANN, Kerstine , MINSHULL, Stephen , HEALD, Michael , JAY, Graham
发明人： HEMMANN, Kerstine , MINSHULL, Stephen , HEALD, Michael , JAY, Graham
IPC分类号： A61M5/32
CPC分类号： A61M5/32 , A61M5/326 , A61M5/3271 , A61M5/348 , A61M5/425 , A61M2005/3103 , A61M2005/3104
摘要： The invention relates to an injection supporting device (1) for a syringe (5). The syringe (5) comprises a cartridge (51) for a medicament and may comprise an injection needle (6) extending in a z-direction from the cartridge (51) to dispense the contents of the cartridge (51). Alternatively the injection needle (6) may be part of the injection supporting device (1) itself. The injection supporting device (1) comprises a housing (2) to receive at least a part of the cartridge (51), a needle shield (3) and a resilient member coupled to the needle shield (3) and the housing (2). The needle shield (3) comprises a distal portion (31) and a proximal portion (33), a distal opening (311) in a front end of the distal portion (31) and a needle guide for guiding the injection needle (6) towards the distal opening (311). The needle shield (3) is slidably attached to the housing (2) and slidable relative to the housing (2) along the z-direction between a guarding position covering a tip (61) of the injection needle (6) and an injection position in which a front end portion (62) of the injection needle (6) extends through the distal opening (311) of the needle shield (3). The resilient member urges the needle shield (3) towards the guarding position.
摘要翻译：本发明涉及一种用于注射器（5）的注射支撑装置（1）。注射器（5）包括用于药物的药筒（51），并且可以包括从药筒（51）沿z方向延伸以分配药筒（51）的内容物的注射针（6）。或者，注射针（6）可以是注射支撑装置（1）本身的一部分。注射支撑装置（1）包括用于容纳药筒（51）的至少一部分的壳体（2），针护罩（3）和联接到针罩（3）和壳体（2）的弹性构件，。针罩（3）包括远端部分（31）和近端部分（33），远端部分（31）的前端中的远端开口（311）和用于引导注射针头（6）的针引导件朝向远端开口（311）。针罩（3）可滑动地附接到壳体（2）并且可以沿着Z方向相对于壳体（2）在覆盖注射针（6）的尖端（61）的防护位置与注射位置其中所述注射针（6）的前端部分（62）延伸穿过所述针罩（3）的远端开口（311）。弹性构件将针护罩（3）推向护罩位置。

2. 发明申请

WO2010086273A1 CARTRIDGE AND MEDICATION DELIVERY DEVICE 审中-公开
标题翻译：药盒和药物递送装置
公开(公告)号：WO2010086273A1
公开(公告)日：2010-08-05
申请号：PCT/EP2010/050670
申请日：2010-01-21
申请人： Sanofi-Aventis Deutschland GmbH , MACARTHUR, Ross , JAY, Graham , SMITH, Christopher James
发明人： MACARTHUR, Ross , JAY, Graham , SMITH, Christopher James
IPC分类号： A61M5/28 , B65D83/00
CPC分类号： A61M5/282 , A61M5/286 , A61M5/30 , A61M5/3243 , A61M2005/3118 , A61M2005/3123 , A61M2005/31508 , A61M2005/3247
摘要： A single-use cartridge for a medication delivery device, comprises a body element (1) having a proximal end and a distal end, a dispensing means (5), and a deformable capsule (3) containing medication. The capsule (3) is disposed inside the body element (1) and has a skin which encases the medication. The capsule (3) is configured to be pushed in the distal direction against the dispensing means (4) so that the content of the capsule (3) is dispensed.
摘要翻译：用于药物输送装置的一次性药筒包括具有近端和远端的身体元件（1），分配装置（5）和包含药物的可变形胶囊（3）。胶囊（3）设置在身体元件（1）的内部并具有包裹药物的皮肤。胶囊（3）构造成沿着远端方向被推靠在分配装置（4）上，使得胶囊（3）的内容物被分配。

3. 发明申请

WO2010139670A1 MEDICATED MODULE FOR A DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于药物递送装置的药物模块
公开(公告)号：WO2010139670A1
公开(公告)日：2010-12-09
申请号：PCT/EP2010/057578
申请日：2010-06-01
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , DE SAUSMAREZ LINTELL, Daniel Thomas , BOYD, Malcolm Stanley , DAVIES, James Alexander , WIMPENNY, Steven , REKAYA, Naceur , BILTON, Simon Lewis , CROSS, John David , MOORE, David , JAY, Graham , MACARTHUR, Ross Douglas , HEALD, Michael James David , SMITH, Christopher James
发明人： DE SAUSMAREZ LINTELL, Daniel Thomas , BOYD, Malcolm Stanley , DAVIES, James Alexander , WIMPENNY, Steven , REKAYA, Naceur , BILTON, Simon Lewis , CROSS, John David , MOORE, David , JAY, Graham , MACARTHUR, Ross Douglas , HEALD, Michael James David , SMITH, Christopher James
IPC分类号： A61M5/24 , A61M5/315 , A61M5/00
CPC分类号： A61M5/2448 , A61M5/2466 , A61M5/31525 , A61M5/31556 , A61M5/32 , A61M5/3294 , A61M5/347 , A61M2005/1787 , A61M2206/20
摘要： A medicated module (4) for an injection system to co-deliver at least two medicaments (1, 2) is disclosed where a primary delivery device (7) containing a primary medicament (1) accepts a medicated module (4) containing a single dose of a secondary medicament (2) and where both medicaments (1, 2) are delivered through a single hollow needle (3, 16, 21, 31).
摘要翻译：公开了一种用于共同递送至少两种药物（1,2）的注射系统的药物组件（4），其中包含主要药物（1）的主要输送装置（7）接受含有单一药物的药物模块（4）二次药剂（2）的剂量，并且其中两种药物（1,2）通过单个中空针（3,16,21,31）递送。

4. 发明申请

WO2010139666A1 DELIVERY OF TWO OR MORE MEDICAMENTS THROUGH A SINGLE DOSE SELECTION AND DISPENSE INTERFACE 审中-公开
标题翻译：通过单剂量选择和配方接口递送两种或多种药物
公开(公告)号：WO2010139666A1
公开(公告)日：2010-12-09
申请号：PCT/EP2010/057571
申请日：2010-06-01
申请人： Sanofi-Aventis Deutschland GmbH , De Sausmarez Lintell, Daniel Thomas , Boyd, Malcolm Stanley , Leak, David Martin , Keating, Carmen Patricia , Sanders, David , Marshall, Elizabeth Anne , Jay, Graham , MacArthur, Ross Douglas Laurie , Heald, Michael James David , Smith, Christopher James , Ortiz, Elliot Lucas
发明人： De Sausmarez Lintell, Daniel Thomas , Boyd, Malcolm Stanley , Leak, David Martin , Keating, Carmen Patricia , Sanders, David , Marshall, Elizabeth Anne , Jay, Graham , MacArthur, Ross Douglas Laurie , Heald, Michael James David , Smith, Christopher James
IPC分类号： A61M5/315 , A61M5/00
CPC分类号： A61M5/2448 , A61M5/2455 , A61M5/31551 , A61M5/31561 , A61M5/3294 , A61M2005/1787 , A61M2005/3142
摘要： An injection system for co-delivery of two medicaments (1, 2) having a drug delivery device (7) containing a primary reservoir (11) containing a first medicament (1) and having a secondary reservoir (5, 17, 30) containing a second medicament (2) where the drug delivery device (7) has only one dose setter (12) for the primary reservoir (11) and that automatically determines the dose of the second medicament (2). Both medicaments (1, 2) are delivered through a single dispense interface (3, 16, 21, 31).
摘要翻译：一种用于共同递送具有药物输送装置（2）的两种药物（1,2）的注射系统，所述药物输送装置（7）包含含有第一药剂（1）并具有第二储存器（5,17,30）的主储存器，第二药物（2），其中药物递送装置（7）仅具有用于主储存器（11）的一个剂量设定器（12）并且自动确定第二药剂（2）的剂量。两种药物（1,2）都通过一个分配界面（3,16,21,31）进行输送。

5. 发明申请

WO2012062843A1 DRUG DELIVERY DEVICE AND METHOD FOR A DRUG DELIVERY DEVICE 审中-公开
标题翻译：用于药物递送装置的药物递送装置和方法
公开(公告)号：WO2012062843A1
公开(公告)日：2012-05-18
申请号：PCT/EP2011/069815
申请日：2011-11-10
申请人： SANOFI-AVENTIS DEUTSCHLAND GMBH , SCHABBACH, Michael , JAY, Graham
发明人： SCHABBACH, Michael , JAY, Graham
IPC分类号： A61M5/20 , A61M5/24
CPC分类号： A61M5/31535 , A61M5/1684 , A61M5/2066 , A61M5/2448 , A61M5/3129 , A61M5/3146 , A61M5/31541 , A61M5/31596 , A61M2005/2485 , A61M2205/3306 , A61M2205/3389 , A61M2205/587 , G06F19/3462
摘要： A drug delivery device (1) is provided comprising a container (4), a first product (13A) and a second product (13B). The device (1) is configured to mix the first product (13A) and the second product (13B) with each other within the container (4) for forming a drug mixture (13A, 13B). The device (1) is further configured for dispensing the drug mixture (13A, 13B). The device (1) comprises a mixing member (20). The device (1) is switchable from a first state, in which the first product (13A) and the second product (13B) are separated, into a second state, in which the first product (13A) and the second product (13B) are mixed. The mixing member (20) is configured to exert a force onto the container (4) in order to move the container (4) to mix the first product (13A) and the second product (13B) with each other. Furthermore, a method for maintaining a predetermined property of a drug mixture (13A, 13B) to be dispensed from a drug delivery device (1) is provided.
摘要翻译：提供了药物输送装置（1），其包括容器（4），第一产品（13A）和第二产品（13B）。装置（1）被构造成在容器（4）内将第一产品（13A）和第二产品（13B）彼此混合以形成药物混合物（13A，13B）。装置（1）还被配置用于分配药物混合物（13A，13B）。装置（1）包括混合构件（20）。装置（1）可从第一产品（13A）和第二产品（13B）分离的第一状态切换到第二状态，其中第一产品（13A）和第二产品（13B）混合混合构件（20）构造成向容器（4）施加力以移动容器（4）以将第一产品（13A）和第二产品（13B）彼此混合。此外，提供了用于保持从药物输送装置（1）分配的药物混合物（13A，13B）的预定特性的方法。

6. 发明申请

WO1993017663A1 PHARMACEUTICAL INHALATION COMPOSITIONS 审中-公开
标题翻译：药物吸入组合物
公开(公告)号：WO1993017663A1
公开(公告)日：1993-09-16
申请号：PCT/GB1993000503
申请日：1993-03-10
申请人： FISONS PLC , BASKEYFIELD, Lewis, James , JAY, Graham, Frederick , WRIGHT, Paul
发明人： FISONS PLC
IPC分类号： A61K09/00
CPC分类号： A61K9/0075
摘要： Non-pressurised pharmaceutical inhalation compositions comprising a therapeutically effective amount of a particulate inhalation medicament having a mass median diameter in the range 0.01 to 15 mu m and a particulate polysaccharide entrapped flavouring agent having a mass median diameter in the range 10 to 200 mu m.
摘要翻译：非加压药物吸入组合物，其包含治疗有效量的质量中值直径在0.01至15μm范围内的颗粒吸入药物和质量中值直径在10至200μm范围内的颗粒状多糖包埋调味剂。

7. 发明授权

US09592342B2 Delivery of two or more medicaments through a single dose selection and dispense interface 有权
标题翻译：通过单剂量选择和分配界面递送两种或更多种药物
公开(公告)号：US09592342B2
公开(公告)日：2017-03-14
申请号：US13375525
申请日：2010-06-01
申请人： Daniel Thomas De Sausmarez Lintell , Malcolm Stanley Boyd , David Martin Leak , Carmen Patricia Keating , David Sanders , Elizabeth Anne Marshall , Jay Graham , Ross Douglas Laurie MacArthur , Michael James Heald , Christopher James Smith , Elliot Lucas Ortiz
发明人： Daniel Thomas De Sausmarez Lintell , Malcolm Stanley Boyd , David Martin Leak , Carmen Patricia Keating , David Sanders , Elizabeth Anne Marshall , Jay Graham , Ross Douglas Laurie MacArthur , Michael James Heald , Christopher James Smith , Elliot Lucas Ortiz
IPC分类号： A61M5/31 , A61M5/24 , A61M5/32 , A61M5/315 , A61M5/178
CPC分类号： A61M5/2448 , A61M5/2455 , A61M5/31551 , A61M5/31561 , A61M5/3294 , A61M2005/1787 , A61M2005/3142
摘要： An injection system for co-delivery of two medicaments (1, 2) having a drug delivery device (7) containing a primary reservoir (11) containing a first medicament (1) and having a secondary reservoir (5, 17, 30) containing a second medicament (2) where the drug delivery device (7) has only one dose setter (12) for the primary reservoir (11) and that automatically determines the dose of the second medicament (2). Both medicaments (1, 2) are delivered through a single dispense interface (3, 16, 21, 31).
摘要翻译：一种用于共同递送具有药物输送装置（2）的两种药物（1,2）的注射系统，所述药物输送装置（7）包含含有第一药剂（1）并具有第二储存器（5,17,30）的主储存器，第二药物（2），其中药物递送装置（7）仅具有用于主储存器（11）的一个剂量设定器（12）并且自动确定第二药剂（2）的剂量。两种药物（1,2）都通过一个分配界面（3,16,21,31）进行输送。

8. 发明申请

US20130226134A1 DRUG DELIVERY DEVICE AND METHOD FOR A DRUG DELIVERY DEVICE 有权
标题翻译：用于药物递送装置的药物递送装置和方法
公开(公告)号：US20130226134A1
公开(公告)日：2013-08-29
申请号：US13883391
申请日：2011-11-10
申请人： Michael Schabbach , Jay Graham
发明人： Michael Schabbach , Jay Graham
IPC分类号： A61M5/315
CPC分类号： A61M5/31535 , A61M5/1684 , A61M5/2066 , A61M5/2448 , A61M5/3129 , A61M5/3146 , A61M5/31541 , A61M5/31596 , A61M2005/2485 , A61M2205/3306 , A61M2205/3389 , A61M2205/587 , G06F19/3462
摘要： A drug delivery device is provided comprising a container, a first product and a second product. The device is configured to mix the first product and the second product with each other within the container for forming a drug mixture. The device is further configured for dispensing the drug mixture. The device comprises a mixing member. The device is switchable from a first state, in which the first product and the second product are separated, into a second state, in which the first product and the second product are mixed. The mixing member is configured to exert a force onto the container in order to move the container to mix the first product and the second product with each other. Furthermore, a method for maintaining a predetermined property of a drug mixture to be dispensed from a drug delivery device is provided.
摘要翻译：提供了药物输送装置，其包括容器，第一产品和第二产品。该装置被配置为将第一产品和第二产品彼此混合在容器内用于形成药物混合物。该装置还被配置用于分配药物混合物。该装置包括混合构件。该装置可从第一产品和第二产品分离的第一状态切换成第二状态，其中混合第一产品和第二产品。混合构件被构造成向容器施加力以移动容器以使第一产品和第二产品彼此混合。此外，提供了用于维持从药物输送装置分配的药物混合物的预定特性的方法。

9. 发明申请

US20120136334A1 Delivery of Two or More Medicaments Through a Single Dose Selection and Dispense Interface 有权
标题翻译：通过单剂量选择和分配接口交付两种或更多种药物
公开(公告)号：US20120136334A1
公开(公告)日：2012-05-31
申请号：US13375525
申请日：2010-06-01
申请人： Daneil Thomas De Sausmarez Lintell , Malcolm Stanley Boyd , David Martin Leak , Carmen Patricia Keating , David Sanders , Elizabeth Anne Marshall , Jay Graham , Ross Douglas Laurie MacArthur , Michael James Heald , Christopher James Smith , Elliot Lucas Ortiz
发明人： Daneil Thomas De Sausmarez Lintell , Malcolm Stanley Boyd , David Martin Leak , Carmen Patricia Keating , David Sanders , Elizabeth Anne Marshall , Jay Graham , Ross Douglas Laurie MacArthur , Michael James Heald , Christopher James Smith , Elliot Lucas Ortiz
IPC分类号： A61M5/31
CPC分类号： A61M5/2448 , A61M5/2455 , A61M5/31551 , A61M5/31561 , A61M5/3294 , A61M2005/1787 , A61M2005/3142
摘要： An injection system for co-delivery of two medicaments (1, 2) having a drug delivery device (7) containing a primary reservoir (11) containing a first medicament (1) and having a secondary reservoir (5, 17, 30) containing a second medicament (2) where the drug delivery device (7) has only one dose setter (12) for the primary reservoir (11) and that automatically determines the dose of the second medicament (2). Both medicaments (1, 2) are delivered through a single dispense interface (3, 16, 21, 31).
摘要翻译：一种用于共同递送具有药物输送装置（2）的两种药物（1,2）的注射系统，所述药物输送装置（7）包含含有第一药剂（1）并具有第二储存器（5,17,30）的主储存器，第二药物（2），其中药物递送装置（7）仅具有用于主储存器（11）的一个剂量设定器（12）并且自动确定第二药剂（2）的剂量。两种药物（1,2）都通过一个分配界面（3,16,21,31）进行输送。

10. 发明授权

US06668429B2 Deep-groove fastener 失效
标题翻译：深沟紧固件
公开(公告)号：US06668429B2
公开(公告)日：2003-12-30
申请号：US10139162
申请日：2002-05-03
申请人： Nobuo Fujisawa , Craig Jay Graham , Wolfgang Eduardo Coronel , Joel William Pfeil
发明人： Nobuo Fujisawa , Craig Jay Graham , Wolfgang Eduardo Coronel , Joel William Pfeil
IPC分类号： A44B2100
CPC分类号： A47C31/023 , Y10T24/309 , Y10T24/32
摘要： The invention is a deep-groove fastener which securely retains a seat cover within the groove of a deeply contoured seat bun. The fastener comprises an elongated body generally concave in cross section and having an interior cavity. A plurality of notched ridges are located on the surface of the interior cavity. The notched ridges serve as fastening elements for engaging loop or other material attached to the underside of a seat cover. Anchor elements are located on the exterior, non-cavity surface of the main body, to aid in anchoring the invention within a foam seat bun. The main body additionally comprises two flange-like sealing legs having a relatively flat bottom surface, to seal the sides of the invention against fouling during the seat bun molding process. Magnetically attractable particles are incorporated into the sealing legs, to hold the invention securely to a magnetized seat bun forming mold.
摘要翻译：本发明是一种深槽紧固件，其将座盖牢固地保持在深刻成型的座圈的槽内。该紧固件包括一个细长的主体，该主体的横截面大体上是凹形的并且具有内部空腔。多个凹口脊位于内腔的表面上。凹槽脊部用作用于接合环或者附接到座盖的下侧的其它材料的紧固元件。锚元件位于主体的外部非空腔表面上，以帮助将本发明锚定在泡沫座un内。主体另外包括两个具有相对平坦的底表面的法兰状密封腿，以在座椅座圈成型过程中密封本发明的两侧以防止结垢。将可吸引的颗粒结合到密封腿中，将本发明牢固地保持在磁化的座圈成型模具上。

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