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1. 发明授权

US07263160B2 Method and device for examining an object 失效
标题翻译：用于检查物体的方法和装置
公开(公告)号：US07263160B2
公开(公告)日：2007-08-28
申请号：US10545063
申请日：2004-02-03
申请人： Jens-Peter Schlomka , Jörg Sabczynski , Jörn Borgert
发明人： Jens-Peter Schlomka , Jörg Sabczynski , Jörn Borgert
IPC分类号： G01N23/04
CPC分类号： G01V5/0016
摘要： In the field of airport baggage inspection, a multi-level screening procedure is used. When a first level screening system (18) detects a “suspicious region” inside a bag, it is transferred to a next level system (2) where the bag gets rescanned. According to the present invention, a device/method is provided for finding and tracking the suspicious region inside the baggage which allows to reduce the area to be rescanned significantly. For this purpose, the image from the first level system together with the position of the suspicious region within the image is transferred from the first level system to the second level system. On arrival of the bag at the second level (21), a simple X-ray transmission image is measured using an additional source/detector system (6). The two images are then rigidly registered in order to exactly determine the suspicious region in the second level scanner system.
摘要翻译：在机场行李检查领域，采用多层次的筛选程序。当第一级筛选系统（18）检测到袋内的“可疑区域”时，将其转移到下一级系统（2），其中袋被重新扫描。根据本发明，提供了一种用于查找和跟踪行李内的可疑区域的装置/方法，其允许显着减少被重新扫描的区域。为此，来自第一级系统的图像以及图像内的可疑区域的位置被从第一级系统传送到第二级系统。在袋子到达第二级（21）时，使用附加的源/检测器系统（6）测量简单的X射线透射图像。然后刚刚登记两个图像以精确地确定第二级扫描器系统中的可疑区域。

2. 发明授权

US09820672B2 Colon screening by using magnetic particle imaging 有权
公开(公告)号：US09820672B2
公开(公告)日：2017-11-21
申请号：US13883603
申请日：2011-11-07
申请人： Jörn Borgert , Ingo Schmale , Jürgen Erwin Rahmer , Bernhard Gleich , Michael Harald Kuhn
发明人： Jörn Borgert , Ingo Schmale , Jürgen Erwin Rahmer , Bernhard Gleich , Michael Harald Kuhn
IPC分类号： A61B5/05 , A61K49/18
CPC分类号： A61B5/0515 , A61B5/05 , A61K49/1818
摘要： A method for colon screening and collecting data by using Magnetic Particle Imaging wherein an imaging magnetic field is generated with a spatial distribution of the magnetic field strength such that the area of examination in the colon consists of a first sub-area with lower magnetic field strength, where the magnetization of a magnetic particle which was pre-delivered to the colon is not saturated, and a second sub-area with a higher magnetic field strength, where the magnetization of said magnetic particle is saturated. The spatial location of both sub-areas in the area of examination is modified so that the magnetization of said particles changes locally. Signals are acquired and are evaluated to obtain information about the spatial distribution of the signals in the area of examination. The method may be carried out during an entire peristaltic cycle in a colon portion or segment.

3. 发明申请

US20130225979A1 COLON SCREENING BY USING MAGNETIC PARTICLE IMAGING 有权
标题翻译：使用磁性粒子成像进行彩色扫描
公开(公告)号：US20130225979A1
公开(公告)日：2013-08-29
申请号：US13883603
申请日：2011-11-07
申请人： Jörn Borgert , Ingo Schmale , Jürgen Erwin Rahmer , Bernhard Gleich , Michael Harald Kuhn
发明人： Jörn Borgert , Ingo Schmale , Jürgen Erwin Rahmer , Bernhard Gleich , Michael Harald Kuhn
IPC分类号： A61B5/05
CPC分类号： A61B5/0515 , A61B5/05 , A61K49/1818
摘要： The present invention relates to a method for colon screening by using Magnetic Particle Imaging comprising the steps of: (a) generating an imaging magnetic field with a spatial distribution of the magnetic field strength such that the area of examination in the colon consists of a first sub-area of the colon with lower magnetic field strength, where the magnetization of a magnetic particle which was pre-delivered to the colon is not saturated, and a second sub-area of the colon with a higher magnetic field strength, where the magnetization of said magnetic particle is saturated; (b) changing the spatial location of both sub-areas in the area of examination so that the magnetization of said particles changes locally; (c) acquiring signals that depend on the magnetization in the area of examination influenced by this change; and (d) evaluating said signals to obtain information about the spatial distribution of the signals in the area of examination. The area of examination in the colon preferably comprises a portion or segment of the colon and steps (a) to (c) may be carried out during an entire peristaltic cycle in said colon portion or segment. The present invention further relates to a corresponding method for collecting data, the use of a magnetic particle for colon screening via Magnetic Particle Imaging, a food stuff or liquid for in vivo diagnostic use comprising a magnetic particle, and a method for preparing a patient for colon screening by using Magnetic Particle Imaging.
摘要翻译：本发明涉及一种通过使用磁性粒子成像进行结肠筛查的方法，包括以下步骤：（a）产生具有磁场强度的空间分布的成像磁场，使得冒号中的检查区域由第一具有较低磁场强度的结肠的子区域，其中预先输送到结肠的磁性颗粒的磁化不饱和，以及具有较高磁场强度的结肠的第二子区域，其中磁化强度的所述磁性颗粒是饱和的; （b）改变检查区域中两个子区域的空间位置，使得所述颗粒的磁化在局部变化; （c）获取取决于受该变化影响的检查区域的磁化强度的信号; 和（d）评估所述信号以获得关于检查区域中的信号的空间分布的信息。结肠检查的区域优选包含结肠的一部分或部分，并且步骤（a）至（c）可以在结肠部分或段中的整个蠕动循环期间进行。本发明还涉及用于收集数据的相应方法，通过磁性粒子成像进行结肠筛选的磁性颗粒的使用，用于包括磁性颗粒的体内诊断用途的食物或液体，以及用于制备患者的方法使用磁粉成像进行结肠筛查。

4. 发明申请

US20060203960A1 Method and device for examining an object 失效
标题翻译：用于检查物体的方法和装置
公开(公告)号：US20060203960A1
公开(公告)日：2006-09-14
申请号：US10545063
申请日：2004-02-03
申请人： Jens-Peter Schlomka , Jörg Sabczynski , Jörn Borgert
发明人： Jens-Peter Schlomka , Jörg Sabczynski , Jörn Borgert
IPC分类号： G01N23/04
CPC分类号： G01V5/0016
摘要： In the field of airport baggage inspection, a multi-level screening procedure is used. When a first level screening system (18) detects a “suspicious region” inside a bag, it is transferred to a next level system (2) where the bag gets rescanned. According to the present invention, a device/method is provided for finding and tracking the suspicious region inside the baggage which allows to reduce the area to be rescanned significantly. For this purpose, the image from the first level system together with the position of the suspicious region within the image is transferred from the first level system to the second level system. On arrival of the bag at the second level (21), a simple X-ray transmission image is measured using an additional source/detector system (6). The two images are then rigidly registered in order to exactly determine the suspicious region in the second level scanner system.
摘要翻译：在机场行李检查领域，采用多层次的筛选程序。当第一级筛选系统（18）检测到袋内的“可疑区域”时，将其转移到下一级系统（2），其中袋被重新扫描。根据本发明，提供了一种用于查找和跟踪行李内的可疑区域的装置/方法，其允许显着减少被重新扫描的区域。为此，来自第一级系统的图像以及图像内的可疑区域的位置被从第一级系统传送到第二级系统。在袋子到达第二级（21）时，使用附加的源/检测器系统（6）测量简单的X射线透射图像。然后刚刚登记两个图像以精确地确定第二级扫描器系统中的可疑区域。

5. 发明授权

US07907989B2 Imaging system for interventional radiology 有权
标题翻译：介入放射成像系统
公开(公告)号：US07907989B2
公开(公告)日：2011-03-15
申请号：US10560686
申请日：2004-06-09
申请人： Jörn Borgert , Jörg Sabczynski
发明人： Jörn Borgert , Jörg Sabczynski
IPC分类号： A61B5/05 , G06K9/00
CPC分类号： A61B5/06 , A61B5/7207 , A61B8/0833 , A61B8/0841 , A61B8/5276 , A61B34/20 , A61B90/39 , A61B2034/2051 , A61B2090/376
摘要： The invention relates to a system and an imaging method for visualizing areas (2) in a moving environment within the body of a patient (1), wherein the position of one or more markers, which are connected to an interventional device (4), is determined and used to determine the position of the areas (2) and/or of the interventional device (4) in images (6) which are recorded of the areas (2) and of their environment. According to the invention, the markers used are active locators which independently of the method used to record the images (6) generate data or signals for determining their position. Such an imaging method, which preferably uses electromagnetic locators, allows a considerably more robust representation of the visualized areas (2), with elimination of movements, than is possible using passive markers.
摘要翻译：本发明涉及一种用于在患者（1）的身体内的移动环境中可视化区域（2）的系统和成像方法，其中连接到介入装置（4）的一个或多个标记的位置，被确定并用于确定在区域（2）及其环境中记录的图像（6）中的区域（2）和/或介入装置（4）的位置。根据本发明，使用的标记是与用于记录图像（6）生成用于确定其位置的数据或信号的方法无关的有源定位器。优选地使用电磁定位器的这种成像方法允许可视化区域（2）的显着更强大的表示，消除运动，而不是使用被动标记。

6. 发明授权

US07400136B2 Multiscale localization procedure 有权
标题翻译：多尺度定位程序
公开(公告)号：US07400136B2
公开(公告)日：2008-07-15
申请号：US10553771
申请日：2004-04-14
申请人： Jörn Borgert , Volker Rasche
发明人： Jörn Borgert , Volker Rasche
IPC分类号： G01B7/15 , H01F5/00 , G01N27/72
CPC分类号： A61B5/061 , A61B5/06 , A61B6/12 , A61B6/469
摘要： Position measurements are often performed using a localization system with a given fixed capture range and accuracy and resolution. Having a fixed capture range often comes at the cost of decreased accuracy and resolution. At the start, a large capture range is provided where the accuracy and resolution is low. In this large capture area, the target area can be identified and aimed at. With this identification, a smaller capture range is iteratively provided and centered around the region of interest, which leads to an increased accuracy and resolution.
摘要翻译：位置测量通常使用具有给定的固定捕获范围和精度和分辨率的定位系统执行。具有固定的捕获范围通常来自降低精度和分辨率的代价。在开始时，提供了一个大的捕获范围，其精度和分辨率低。在这个大的捕获区域，目标区域可以被识别和瞄准。通过这种识别，迭代地提供较小的捕获范围并以感兴趣的区域为中心，这导致增加的精度和分辨率。

7. 发明申请

US20060251300A1 Imaging system for interventional radiology 有权
标题翻译：介入放射成像系统
公开(公告)号：US20060251300A1
公开(公告)日：2006-11-09
申请号：US10560686
申请日：2004-06-09
申请人： Jörn Borgert , Jörg Sabczynski
发明人： Jörn Borgert , Jörg Sabczynski
IPC分类号： G06K9/00
CPC分类号： A61B5/06 , A61B5/7207 , A61B8/0833 , A61B8/0841 , A61B8/5276 , A61B34/20 , A61B90/39 , A61B2034/2051 , A61B2090/376
摘要： The invention relates to a system and an imaging method for visualizing areas (2) in a moving environment within the body of a patient (1), wherein the position of one or more markers, which are connected to an interventional device (4), is determined and used to determine the position of the areas (2) and/or of the interventional device (4) in images (6) which are recorded of the areas (2) and of their environment. According to the invention, the markers used are active locators which independently of the method used to record the images (6) generate data or signals for determining their position. Such an imaging method, which preferably uses electromagnetic locators, allows a considerably more robust representation of the visualized areas (2), with elimination of movements, than is possible using passive markers.
摘要翻译：本发明涉及一种用于在患者（1）的身体内的移动环境中可视化区域（2）的系统和成像方法，其中连接到介入装置（4）的一个或多个标记的位置，被确定并用于确定在区域（2）及其环境中记录的图像（6）中的区域（2）和/或介入装置（4）的位置。根据本发明，使用的标记是与用于记录图像（6）生成用于确定其位置的数据或信号的方法无关的有源定位器。优选地使用电磁定位器的这种成像方法允许可视化区域（2）的显着更强大的表示，消除运动，而不是使用被动标记。

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