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1. 发明申请

WO1997047353A1 COMPOSITION AND SYSTEM FOR IONTOPHORETIC TRANSDERMAL DELIVERY OF DRUGS 审中-公开
标题翻译：组合物和系统用于药物的绝缘输送
公开(公告)号：WO1997047353A1
公开(公告)日：1997-12-18
申请号：PCT/FI1997000319
申请日：1997-05-27
申请人： NOVAGENT OY , JÄRNSTRÖM, Risto , HIRVONEN, Jouni
发明人： NOVAGENT OY
IPC分类号： A61N01/30
CPC分类号： A61N1/30 , A61K9/0009
摘要： The present invention relates to a pharmaceutical composition for the controlled iontophoretic transdermal delivery of a drug comprising a combination of a drug and an electrically conductive carrier, wherein the administration of the drug to the patient is intended to be enhanced by leading an electrical current from said composition to the patient's skin. According to the invention the electrically conductive carrier is a textile fiber with an ion exchanger group grafted thereto. According to a preferred embodiment the drug is tacrine or its pharmaceutically acceptable salt. The invention further concerns a system for the iontophoretic transdermal delivery of a drug to a patient. In this system, the pharmaceutical composition (22) is attached to the patient's skin and used as one of the poles connected to a source (30) of direct current.
摘要翻译：本发明涉及一种用于受控离子电渗透皮递送药物的药物组合物，其包含药物和导电载体的组合，其中药物给予患者的目的是通过引导来自所述组合到患者的皮肤。根据本发明，导电载体是具有接枝到其上的离子交换剂基团的纺织纤维。根据优选的实施方案，该药物是他克林或其药学上可接受的盐。本发明还涉及用于将药物的离子电渗透皮递送给患者的系统。在该系统中，药物组合物（22）附接到患者的皮肤上并且用作连接到直流源（30）的极中的一个。

2. 发明申请

WO1992022354A1 COMPOSITE FOR PROTECTIVE GARMENT 审中-公开
标题翻译：复合保护服装
公开(公告)号：WO1992022354A1
公开(公告)日：1992-12-23
申请号：PCT/FI1992000182
申请日：1992-06-10
申请人： FINEX OY , JÄRNSTRÖM, Risto
发明人： FINEX OY
IPC分类号： A62D05/00
CPC分类号： B32B5/26 , A62D5/00 , B32B5/16 , B32B2310/0806 , B32B2571/02
摘要： The invention relates to a composite for protective garment, comprising an inner layer (1), an outer layer (3) spaced apart from said inner layer, and at least one intermediate layer (2, 4, 5). According to the invention, the composite contains in particular two intermediate layers (2, 4), both of which are comprised of a fibrous ion exchange material, the layer (2) adjacent to the outer layer containing ion exchange groups in acid form and the layer (4) adjacent to the inner layer containing ion exchange groups in base form. The composite according to the invention may be used for the manufacturing of suits protecting against CW gases and toxic industrial chemicals.
摘要翻译：本发明涉及一种用于防护服的复合材料，包括内层（1），与所述内层间隔开的外层（3）和至少一层中间层（2,4,5）。根据本发明，复合材料特别包含两个中间层（2,4），两个中间层都由纤维离子交换材料组成，邻近外层的层（2）含有酸形式的离子交换基团，层（4）邻近包含基底形式的离子交换基团的内层。根据本发明的复合材料可用于制造防止CW气体和有毒工业化学品的衣服。

3. 发明申请

WO1997027844A1 COMPOSITION FOR TRANSDERMAL DELIVERY OF DRUGS 审中-公开
标题翻译：用于药物转运的组合物
公开(公告)号：WO1997027844A1
公开(公告)日：1997-08-07
申请号：PCT/FI1997000039
申请日：1997-01-27
申请人： NOVAGENT OY , JÄRNSTRÖM, Risto , HIRVONEN, Jouni
发明人： NOVAGENT OY
IPC分类号： A61K09/70
CPC分类号： A61K31/00 , A61K9/70 , A61K47/585
摘要： The present invention relates to a pharmaceutical composition for the controlled transdermal delivery of a drug comprising a combination of a drug and a ion exchanger group grafted to a carrier, and a pharmaceutically acceptable salt that is able to control the release of the drug from the ion exchanger. According to the invention the carrier is a textile fiber. According to a preferred embodiment the drug is tacrine or its pharmaceutically acceptable salt.
摘要翻译：本发明涉及用于受控经皮递送药物的药物组合物，其包括药物和接枝到载体上的离子交换剂基团的组合，以及能够控制药物从离子释放的药学上可接受的盐器。根据本发明，载体是纺织纤维。根据优选的实施方案，该药物是他克林或其药学上可接受的盐。

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