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    • 6. 发明申请
    • IONTOPHORETIC DEVICE FOR DOSAGING OF AN ACTIVE INGREDIENT
    • 用于计量活性成分的静电装置
    • WO2014027136A1
    • 2014-02-20
    • PCT/FI2013/050782
    • 2013-07-31
    • NOVAGENT OYKONTTURI, KyöstiHIRVONEN, JouniVIITALA, LauriPOHJAKALLIO, Maija
    • KONTTURI, KyöstiHIRVONEN, JouniVIITALA, LauriPOHJAKALLIO, Maija
    • A61N1/30
    • A61N1/325A61M35/00A61N1/30
    • A device based on iontophoresis and intended for transdemal dosing of an active agent, said device comprising - a pair of electrodes (11,12), which can be connected to a direct-current source, and - two chambers (13, 14), separated from each other, the first chamber (13) containing the active agent, each chamber having a porous membrane (15, 16) on the side facing the individual's skin, and - the first chamber (13) being divided in two sections (13a, 13b) in such a manner that the first chamber section ( 13 a) is in contact with the electrode (11) and the second chamber section (13b) is in contact with the membrane (15) coming into contact with an individul's skin, wherein between the chamber sections (13a and 13b) is a membrane (18) selectively permeable either to cations or to anions, - the first chamber section (13a) containing an electrolyte and the second chamber section (13b) containing the ionic active agent, bound to a ion exhanger therein, which in turn preferably comprises fibres and ion exchanging groups bound thereto. The invention is characterized in that - the electrodes (11,12) comprise a porous carbon fibre textile (30) which is mixed with a hydrophobic agent or onto which is fitted a hydrophobic porous, preferably micro-porous membrane (31), and - into the chamber section (13a) comprising the analyte is added a fibre grafted with buffering ion exchanging groups.
    • 一种基于离子电渗疗法并用于递送剂量的活性剂的装置,所述装置包括 - 可连接到直流源的一对电极(11,12),以及 - 两个腔室(13,14), 彼此分离,所述第一室(13)含有活性剂,每个室在面向个人皮肤的一侧上具有多孔膜(15,16),以及 - 第一室(13)被分成两部分(13a ,13b),使得第一室部(13a)与电极(11)接触,第二室部(13b)与与个体皮肤接触的膜(15)接触, 其中在所述室部分(13a和13b)之间是阳离子或阴离子选择性渗透的膜(18), - 含有电解质的第一室部分(13a)和含有离子活性剂的第二室部分(13b) 结合到其中的离子去除器,其又优选地包括fi bres和离子交换基。 本发明的特征在于 - 电极(11,12)包括与疏水剂混合的多孔碳纤维织物(30),或者在其上装配有疏水多孔,优选微孔膜(31),和 - 进入包含分析物的室部分(13a)中加入接枝有缓冲离子交换基团的纤维。
    • 8. 发明申请
    • VEHICLE AXLES WITH VARIABLE TRACK WIDTH
    • 具有可变轨迹宽度的车辆轴
    • WO2012084827A1
    • 2012-06-28
    • PCT/EP2011/073242
    • 2011-12-19
    • VALTRA OY ABHANNUKAINEN, PetriRINTOO, MikkoHIRVONEN, Jouni
    • HANNUKAINEN, PetriRINTOO, MikkoHIRVONEN, Jouni
    • B62D49/00B62D55/00
    • B60B35/125B60B35/1054B60B35/12B60B2900/531B62D49/0678
    • A variable track width vehicle axle has an outer axle casing (12) which supports two drive shafts (13) which are driven at their inner ends by drive means (23) and carry wheel attachment means (13a) at their outer ends. Each drive shaft including first and second parts (13a,13b) which are in screw-threaded engagement with each other so that rotation of one part relative to the other changes the effective length of each shaft and thus the track width of the axle. A clutch means (16) is also provided which in a first position connects the two parts (13a, 13b) of each shaft to prevent relative rotation and in a second position disconnects the two parts of each shaft to allow relative rotation therebetween and rotates one of the screw threaded parts relative to the other part (13b) via the drive means (23) to change the effective length of each drive shaft.
    • 可变轨道宽度车轴具有外轴壳体(12),其支撑两个驱动轴(13),驱动轴在其内端由驱动装置(23)驱动,并在其外端承载轮附接装置(13a)。 每个驱动轴包括彼此螺纹接合的第一和第二部分(13a,13b),使得一个部分相对于另一部分的旋转改变每个轴的有效长度,从而改变轴的轨道宽度。 还设置有离合器装置(16),其在第一位置连接每个轴的两个部分(13a,13b)以防止相对旋转,并且在第二位置中,分离每个轴的两个部分以允许它们之间的相对旋转,并且旋转一个 的螺纹部分经由驱动装置(23)相对于另一部分(13b),以改变每个驱动轴的有效长度。